摘要
研究了4种补益中药对大鼠脾淋巴细胞产生TL—2及其作用的影响。结果显示党参、淫羊藿有促进ConA活化的小鼠脾淋巴细胞增殖的作用,麦冬、鸡血藤则无。上述2种中药促进ConA活化的小鼠脾淋巴细胞增殖是由于促进大鼠脾淋巴细胞产生TL—2所致。另一方面,4种中药无明显促进、甚至抑制ConA活化的淋巴细胞对TL—2的反应性。淫羊藿对环磷酰胺(CY;100mg/kg,1次)抑制的大鼠脾淋巴细胞产生IL—2有改善作用。
In this paper,the effects of four reinforcing Chinese herbs on the interleukin—2(IL —2) production and action were investigated.The results showed that both Redix Codonopsis Pilosulae and Herba Epimedii are able to significantly stimulate the proliferetion of ConA—activated murine splenic lymphocytes,Radix Ophiopogonis and Canlis Spatholobi have no such effects.The proliferation stimulating effects of the above two Chinese herbs to ConA—activated murine splentic lymphocytes are due to promotion of IL—2 production.On the other hand,the four reinforcing Chinese herbs have no apparent promoting effect on the responsiveness of ConA—activated murine splenic lymphocytes for IL —2.On the contrary they may inhibit such responsiveness.Herba Epimedii is able to significantly in- crease IL—2 level of cyclophophomidum(CY 100mg/kg)—impaired mice.
出处
《福建中医学院学报》
1993年第4期218-220,共3页
Journal of Fujian College of Traditional Chinese Medicine
关键词
免疫活性
中药
药理学
白细胞介素2
mitogenic factor,lymphocyte/biosyn
immunology competence/drug eff
adjuvant,immunity
Radix Codonopsis Pilosulae/pharm
Radix Ophiopogonis/pharm
Herba Epimedii/pharm
Caulis Spatholobi/pharm
