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骨髓间质干细胞定向分化与骨质疏松症的研究进展

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摘要 骨髓间质干细胞具有多向分化潜能,在成年人的骨骼中它主要分化为成骨细胞和脂肪细胞,二者分化比例失衡,脂肪细胞增多,成骨细胞减少,导致骨量的下降,可能是骨质疏松发生发展的重要原因。多种激素和局部性细胞因子在凋控其双向分化过程中起着重要作用,了解它们的作用机理,从而调控其分化方向,将为骨质疏松的防治提供新的思路及方法。
作者 蒋谊 魏启幼
出处 《国外医学(老年医学分册)》 2004年第4期181-184,共4页 Foreign Medical Sciences(Geriatrics)
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