摘要
目的 探讨检测血清与腹水血管内皮生长因子 (VEGF)对消化系恶性肿瘤的诊断及良、恶性腹水鉴别诊断的价值。方法 采用酶联免疫吸附法 (ELISA法 )检测 5 8例消化系疾病患者血清与腹水VEGF含量。结果 消化系肿瘤患者血清与腹水中VEGF含量明显高于良性疾病患者 (P <0 .0 1)。联合检测血清与腹水VEGF含量 ,其诊断肿瘤性腹水的敏感性较单独检测腹水VEGF有明显提高 (P <0 .0 5 )。
Objective To approach the diagnostic and differential diagnostic values of serum and ascites VEGF measurement for the alimentary tract malignant tumors with the ascites.Methods The VEGF levels in serum and ascites were measured by ELISA in 58 specimens.Results The serum and ascites VEGF levels in the alimentary tract malignant tumors were significantly higher than those in benign diseases( P <0.01) The sensitivity to diagnose the malignant ascites by combining serum and ascites VEGF was obviously increased compared to ascites VEGF level alone( P <0.05).Conclusion The serum and ascites VEGF levels may contribute to diagnosis of the alimentary tract malignant tumors and the differential diagnosis of the ascites.
出处
《临床内科杂志》
CAS
北大核心
2004年第7期463-464,共2页
Journal of Clinical Internal Medicine
基金
江苏省 1 35重点人才课题资助 (基金编号 :37RC2 0 0 2 0 37)
关键词
血管内皮生长因子
腹水
肿瘤/诊断
Vascular endothelial growth factor
Ascites
Neoplasms/diagnosis
