摘要
目的 研究胸腔闭式引流并胸内注射尿激酶治疗结核性胸膜炎的疗效。方法 将收治的 12 9例中量以上积液的结核性胸膜炎病人作为研究对象 ,将患者随机分为 3组 ,A组 4 5例 ,胸腔闭式引流并胸内注射尿激酶治疗 ,B组 4 5例 ,单纯胸腔闭式引流 ,C组 39例反复胸腔穿刺抽水 ;3组患者临床资料无差别 ,具有可比性 ;治疗 1个月和 6个月检查 ,显效为无胸膜肥厚粘连 ,有效为胸膜肥厚粘连 ,无效为胸腔包裹性积液 ;结果进行统计学分析。结果 治疗 1个月和 6个月检查 ,A组显效 4 1例和 4 3例 ,有效 3例和 2例 ,无效 1例和 0例 ;B组显效 31例和 34例 ,有效 10例和9例 ,无效 4例和 2例 ;C组显效 10例和 15例 ,有效 18例和 19例 ,无效 11例和 5例 ;A组较B组 ,B组较C组 ,差异均有有统计学意义。结论 胸腔闭式引流并胸内注射尿激酶促进胸水吸收、防止胸膜肥厚、粘连 ,疗效肯定。
Objective To assess the role of closing drainage and injecting the urokinase to the chest of the patients with tuberculosis pleuritis. Methods One hundred and twenty-nine patients with tuberculosis pleuritis who had moderate and severe pleural effusion,were randomly divided into three groups, group A,45 patients treated with closing drainage and injecting the urokinase to the chest, group B, 45 patients treated with closing drainage only, group C, 39 patients treated with ordinary therapy. Results Evaluating the response after one month and six months, group A,showed obvious effect in 41 and 43,partial 3 and 2,no response 1 and 0 case;group B showed obvious effect in 31 and 34, partial 10 and 9,no response 4 and 2 cases; group C showed obvious effect in 10 and 15,partial 18 and 19,no response 11 and 5 cases. The effect of group A was better than that of B, group B′s effect was better than that of group C. Conclusion The therapy of closing drainage and injecting the urokinase to the chest is a good measure in absorbing the pleural effusion and in preventing the pleural thicking.
出处
《临床荟萃》
CAS
北大核心
2004年第14期797-798,共2页
Clinical Focus
关键词
结核
胸膜
胸腔积液
引流
体检
尿激酶
tuberculosis,pleural
pleural effusion
drainage,postural
urokinase
