摘要
An efficient liquid-phase synthesis of isoxazolines through a 1,3-dipolar cycloaddition is described. Soluble polymer-supported acrylate reacted with nitrile oxides generated in-situ, followed by cleavage from the support giving corresponding isoxazolines in high yields and excellent purities.
An efficient liquid-phase synthesis of isoxazolines through a 1,3-dipolar cycloaddition is described. Soluble polymer-supported acrylate reacted with nitrile oxides generated in-situ, followed by cleavage from the support giving corresponding isoxazolines in high yields and excellent purities.
基金
ProjectsupportedbytheNationalNaturalScienceFoundationofChina (No .2 9972 0 37)