摘要
选择了100例正切的食管活检标本进行了组织形态测量。100个受检者中,内镜诊断慢性食管炎者45例,诊断正常者55例。测量结果表明,上皮厚度在慢性食管炎与正常对照组间有明显的不同(P<0.05),基底细胞层厚度在中度食管炎与对照组间也有明显的差异(P<0.05),但是,乳头高度、乳头相对高度和中性白细胞浸润程度在两组间没有区别,因而认为,食管上皮厚度和基底细胞层厚度的改变可以作为用测量方法诊断慢性食管炎和估价食管癌前病变的一个客观指标。
One hundred esophageal endoscopic biopsies were setected &morphometric measurements were performed. Of 100 subjects, 45cases were diagnosed to have chronic esophagitis by endoscopy,and remaining 55 cases were normal. The epithelial thickness wassignificantly different between chronic esophagitis & normalcontrols (P<0.05). The basal cell zone in the group with moderateesophagitis was markedly thicker than that in healthy controls(P<0.05). However, the height of papillae, relative height ofpapillae & the neutrophil infiltation were not different signific- antly between the 2 groups. Thus, it appears that the changes ofepithelial thickeness & the basal cell zone thickness of esophagealmucosa may be an objective evidence for diagnosing chronic esopha-gitis & presuming a precancerous lesion of esophageal cancer.
出处
《临床与实验病理学杂志》
CAS
CSCD
北大核心
1989年第4期205-208,共4页
Chinese Journal of Clinical and Experimental Pathology
