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^(133)Xe吸入法测定颈内动脉系统脑血栓的脑动脉对二氧化碳反应的能力 被引量:2

Responsibility of Cerebral Artery in Cerebral Thrombosis of Internal Carotid Artery to CO_2 Using ^(133)Xe-inhalation Technique
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摘要 用^(133)Xe吸入法测量20例经CT诊断一侧半球单个缺血病灶患者及10名健康人的脑局部区域血流量(rCBF),同时患者均行三维经颅多普勒超声检查。结果显示病例组缺血半球吸3%CO_2前及吸3%CO_2中的rCBF低于健康人组或病例组中非缺血半球的rCBF。认为病灶半球脑动脉对CO_2扩张反应能力降低,即病灶半球脑血管储备力降低,但非病灶半球及正常对照组脑血管储备力正常,而且脑动脉对CO_2反应能力与脑血栓病情程度及颈内动脉阻塞范围和程度相关。病情重的脑血栓或三维经颅多普勒超声示两侧颈内动脉阴塞及/或狭窄的患者rCBF降低明显。 Using 133Xe-inhalation technique quantitative measurements the regional cerebral blood flow (rCBF) was performed in 20 patients with unilateral ischemic lesion in one hemisphere according to cranial CT scan and in 10 normal subjects. Twenty patients had an Ultrasound Doppler examination of neck vessels half a day after rCBF examination. The results showed that rCBF in ischemic hemisphere before and during 3% CO, stimulation was lower than that in normal subjects or in non-ischemic hemisphere of the patients. It suggests that dilative responsibility to CO, in cerebral artery of stroke hemisphere is reduced. That is to say the cerebrovascular reserve capacity in stroke hemisphere was reduced too, but cerebrovascular reserve capacity in the non-stroke hemisphere and in normal subject of control group was normal. We also found cerebrovascular responsibility to CO, or cerebrovascular reserve capacity correlated with severity of clinical cerebral thrombotic illness and extent and degree of internal carotid artery obstruction. It was poor in severe illness or internal carotid obstruction and/or narrow in both sides of the patient group taken by Ultrasound Doppler examination of neck vessels.
作者 谢惠君 崔毅
机构地区 长海医院神经科
出处 《第二军医大学学报》 CAS CSCD 北大核心 1993年第6期506-510,共5页 Academic Journal of Second Military Medical University
关键词 氙133 颈内动脉 脑动脉储备力 133Xe inhalation regional cerebral blood flow, cerebral thrombosis internal carotid artery cerebral artery reserve capacity
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  • 1郑观成.脑老化与老年痴呆(第1版)[M].上海:上海科学技术文献出版社,1994.155.
  • 2张致峰 谢惠君 等.302名正常人的大脑局部区域血流量[J].第二军医大学学报,1992,13:68-68.

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