摘要
报告43例冠心病患者血中 Lpo、SOD、apo A_1,apo B_(100)和 apo E 的变化,并与正常人作了比较,发现冠心病患者血中 Lpo 明显升高,SOD 活性降低,无活性 SOD 增加,SOD/Lpo 比值减小,apo-B_(100)明显升高,apo-E 减少,apo-B_(100)/apo-A_1比值增大。认为 SOD/Lpo 比值、apo B_(100)/apo A_1比值及 apo E 水平在冠心病的诊断中是具有重要意义的指标。并对冠心病人血中 Lpo 变化与 apo 的关系作了讨论。
The blood Lpo,SOD and apolipoproteins were studied in 43 pateints with coronary artery disease.The results showed that Lpo,apo B_(100) and apo-B_(100)/apo—A_1 rate were significantly higer in CAD than in normal human,but the SOD,apo-E were significantly decreased in CAD than in normal human.It suggested that raised lipid-peroxidation rate and abnormal apolipoproteins ratio are important factors in the Pathogenesis of CAD.
出处
《临床心血管病杂志》
CAS
CSCD
北大核心
1989年第3期129-131,共3页
Journal of Clinical Cardiology
