摘要
目的探讨甲基睾丸素对早期妊娠药物流产效果的影响。方法将200例妊娠49d内的妇女随机分为两组———观察组和对照组,观察组采用米非司酮配伍米索前列醇加用甲基睾丸素药物流产,对照组采用米非司酮配伍米索前列醇药物流产,对两组完全流产率、出血量、出血时间、不良反应及月经恢复时间进行比较。结果加用甲基睾丸素的观察组的完全流产率为94%,出血时间为(10.5±4.5)d,分别高于和少于未加甲基睾丸素的对照组,犤87%,(15.6±5.7)d〗,统计学分析P<0.05,观察组的出血量明显少于对照组,两组的副作用及月经恢复时间均无显著性差异(P>0.05)。结论加用甲基睾丸素可改善药流效果,减少出血量,缩短出血时间。
Objective To observe and approach the clinical effects of methyltestosterone on medicinal abortion of early pregnancy with mifepristone and misoprostol. Methods Two hundred women with 49 day's pregnancy were randomly divided into two groups:observation group (100 cases) and control group (100 cases). The observation group was given mifepristone and misoprostol with methyltestosterone, and the control group with mifepristone and misoprostol. Complete abortion rates, bleeding quantity, bleeding time,side-effects and menstruation recovery were observed and compared between the two groups. Results The rate of complete abortion in the observation group (94%) was higher than that in the control group (84%,P<0.05). The average bleeding time in the observation group (10.5±5.7 days, P<0.05) was shorter than that in the control group (15.6±5.7 days, P< 0.05). There was no significant difference in side-effects and menstruation recovery between the two groups (P>0.05).Conclusion Methyltestosterone can improve the effects of mifepristone and misoprostol on medicinal abortion of early pregnancy. In addition, it can reduce the bleeding quantity and shorten the bleeding time.
出处
《中国航天医药杂志》
2004年第3期29-31,共3页
Medical Journal of CASE
