摘要
目的 了解长春地区儿童风湿病(JRD)的流行情况及临床特点,提高诊断水平。方法 收集1992 年至2001 年10年间诊治的病历完整的 JRD临床资料,进行回顾分析。结果 10年间共诊治 JRD患者 806 例,以过敏性紫瘢(AP),幼年特发性关节炎(JIA)、儿童系统性红斑狼疮(SLE)、风湿热(RF)、儿童强直性脊柱炎(JAS)和皮肤粘膜淋巴结综合征(MCLS)较为多见;AP、SLE、MCLS和JAS病例数有上升趋势,而RF呈明显下降趋势。抗核抗体(ANA)、抗双链DNA抗体(dsDNA)对SLE的诊断有较高特异性;而抗链球菌溶血素O抗体(ASO)、类风湿因子可在多种疾病出现。SLE、JIA和JAS确诊时平均病程8个月~5年。结论 AP、SLE、JIA、JAS和MCLS为长春地区常见JRD。10年来JRD病谱处于变化之中。JAS、JIA和SLE 诊断困难,应提高认识,加强早期诊断研究,减少致残和致死率。
Objective To evaluate the prevalence and chinical characteristics of juvenilerheumaticdisease (JRD) in Changchun area, to improve the level of diagnosis and therapy in JRD. Methods The clinical features of JRD in 806 children from 1991 to 2001 were analyzed. Results Totally 806 cases were studied. Anaphylactoid purpura (AP)、juvenile idiopathic arthritis (JIA)、systemic lupus erythematosus(SLE)、rheumatic fever (RF)、 ankylosing spondylitis (JAS)、mucocutaneous lymphnode sydrome (MCLS) in them were common. AP、SLE、MCLS and JAS show an increasing trend but rheumatic fever is evidently descending. The serum ANA and dsDNA are important guide to the diagnosis of SLE; ASO and rheumatoid factor are inexact. The average duration from the onset to diagnosis of the disease were 8 months^5years. Conclusion JRD such as AP、SLE、JIA and MCLS in Changchun area were not rare. All kinds of JRD are changing in ten years. They were diagnosed difficultly pediatrians should pay great attention to the diagnosis of JRD in children and give the right therapy to reduce the damage of JRD.
出处
《深圳中西医结合杂志》
2004年第3期168-171,共4页
Shenzhen Journal of Integrated Traditional Chinese and Western Medicine
关键词
儿童
风湿病
特点
Children
Juvenile Rheumatic Disease
Characteristics
