摘要
目的 :测定急性脑血栓形成患者血清白细胞介素 - 10 (IL - 10 )的水平 ,探讨其临床意义。方法 :采用ELISA检测 5 0例病情不同程度脑血栓形成患者血清IL - 10的水平及变化 ,以 30例正常人 (对照组 )作比较。结果 :发病初期脑血栓组血清IL - 10水平显著低于对照组 (P <0 0 1) ,且随脑梗死程度加重而加重 (P <0 0 1) ,(7～ 10 )天后IL - 10水平上升。结论 :脑血栓形成可能与患者血清IL - 10水平低有关。
Objective To study the clinical significance of changes of serum levels of IL-10 in patients with cerebral thrombosis. Methods Serum levels of IL-10 in 50 patients with cerebral thrombosis and 30 controls were measured with ELISA. The IL-10 levels were again determied in randomly selected 30 of the 50 patients on d7-10. Results The serum levels of IL-10 in patients with cerebral thrombosis within 48 hours of the onset of disease were significantly higher than those in controls (P<0.01), and the larger the size of cerebral infarction, the lower the levels of IL-10. However, the levels of IL-10 measured on d7-10 were not much different from those in controls (P>0.05). Conclusion Low levels of IL-10 may play an important role in the initiation of cerebral thrombosis.
出处
《放射免疫学杂志》
CAS
2004年第3期236-238,共3页
Journal of Radioimmanology
