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Colonoscopy preparation-induced disorders in renal function and electrolytes 被引量:2

Colonoscopy preparation-induced disorders in renal function and electrolytes
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摘要 Colonoscopy and flexible sigmoidoscopy are commonly used mainly for colon cancer screening and detection, but also in several other situations such as inflammatory bowel disease (for diagnosis and follow up) and gastrointestinal hemorrhage. Bowel cleansing preparations mainly include polyethylene glycol and oral sodium phosphate solutions, with the later being most frequently used due to better toleration from patients. Despite their favourable safety profile these agents have been associated with renal function deterioration and electrolyte disorders, some of which were serious or even fatal. The present paper discusses the complications associated with colonoscopy preparation agents. Colonoscopy and flexible sigmoidoscopy are commonly used mainly for colon cancer screening and detection, but also in several other situations such as inflammatory bowel disease (for diagnosis and follow up) and gastrointestinal hemorrhage. Bowel cleansing preparations mainly include polyethylene glycol and oral sodium phosphate solutions, with the later being most frequently used due to better toleration from patients. Despite their favourable safety profile these agents have been associated with renal function deterioration and electrolyte disorders, some of which were serious or even fatal. The present paper discusses the complications associated with colonoscopy preparation agents.
出处 《World Journal of Gastrointestinal Pharmacology and Therapeutics》 CAS 2014年第2期50-54,共5页 世界胃肠药理与治疗学杂志(英文版)(电子版)
关键词 Oral sodium PHOSPHATE HYPERPHOSPHATEMIA HYPOCALCEMIA PHOSPHATE NEPHROPATHY Oral sodium phosphate Hyperphosphatemia Hypocalcemia Phosphate nephropathy
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  • 1Vanner S J,MacDonald P H,Paterson W G,et al.A randomized prospective trial comparing oral sodium phosphate with standard polyethylene glycol-based lavage solution(Golytely)in the preparation of patients for colonoscopy. The American journal of Gastroenterology . 1990
  • 2Stephen M. Cohen M.D.,Steven D. Wexner M.D.,Sander R. Binderow M.D.,Juan J. Nogueras M.D.,Norma Daniel R.N.,Eli D. Ehrenpreis M.D.,Jonathan Jensen M.D.,Gregory F. Bonner M.D.,William B. Ruderman M.D..Prospective, randomized, endoscopic-blinded trial comparing precolonoscopy bowel cleansing methods[J]. Diseases of the Colon & Rectum . 1994 (7)

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