摘要
分析1102例晚期血吸虫病(晚血)临床资料,结果表明,巨脾型晚血最多见,占52.2%(575/1102).脾切除仍为治疗巨牌型晚血的主要手段.晚血的乙型肝炎,肺结核及恶性肿瘤的患病率较高,对乙肝疫苗的免疫应答差.脾切除未增加上述疾病的患病率,但可改善晚血患者对乙肝疫苗的免疫应答.
1 102 cases with advanced schistosomiasis(AS) were analysed. The results showed that patients with splenomegaly were the major type of AS (52.2%) and splenectomy was the primary therapeutic measure for these patients.The prevalence rates of HBsAg and HBcAb, the morbidity of pulmonary tuberculosis and malignant diseases among the patients were significantly greater than that of control. Splenectomy did not influence the occurrence of the above mentioned conditions.The conversion rate of anti-HBs in patients with AS after 3 doses of HBV vaccine was significantly lower than that of control. Splenectomy improved the immunologic response to HBV vaccine in the patients.
出处
《中国血吸虫病防治杂志》
CAS
CSCD
1996年第3期133-136,共4页
Chinese Journal of Schistosomiasis Control
关键词
晚期血吸虫病
巨脾
乙型肝炎
肺结核
肿瘤
免疫应答
Advanced schistosomiasis, splenomegaly, HBV, tuberculosis, malignant diseases, immunologic response
