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氧氟沙星与氟罗沙星治疗下呼吸道感染的疗效与药物经济学分析 被引量:31

Comparison of Cost-effectiveness between Ofloxacin and Fleroxcin in Treatment of Lower Respiratory Infection
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摘要 目的 :比较氧氟沙星与氟罗沙星治疗呼吸道感染两种治疗方案的经济效果。方法 :将 5 8例患者随机分为两组 ,氧氟沙星组 2 8例 ,氟罗沙星组 3 0例分别给予氧氟沙星与氟罗沙星进行治疗 ,用最小成本法进行评价。结果 :氧氟沙星与氟罗沙星治疗下呼吸道感染有效率分别是 85 .71%和 90 .0 0 % ,不良反应发生率分别是 10 .71%和 10 .0 0 % (P >0 .0 5 )。氧氟沙星组的费用C =960 .5 0元 ;氟罗沙星组费用C =2 2 3 1.2 5元 ,敏感度分析结果表明氧氟沙星组的费用较氟罗沙星组低。结论 :氧氟沙星组的成本 Objective:To compare the therapeutic effects and costs between ofloxacin and fleroxacin on patients with lower respiratory infection. Methods:The patients with lower respiratory infection were randomized into two groups: group one received ofloxain, and group two received fleroxcin. Pharmacoeconomy evaluation was performed by minimized cost analysis. Results:The effective rates of group one and group two were 85.71% and 90.00%, the adverse reaction rates were 10.71% and 10.00%(P> 0.05), and the expenditures 960.50 yuan and 2 231.25 yuan, respectively. Conclusion:By the cost-effectiveness analysis ofloxacin is better than that of fleroxcin.
出处 《医药导报》 CAS 2004年第7期507-509,共3页 Herald of Medicine
关键词 氧氟沙星 氟罗沙星 感染 下呼吸道 最小成本分析 Ofloxacin Fleroxcin Lower respiratory infection Minimized cost analysis
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  • 1徐端正.药物经济学及其分析[J].中国新药与临床杂志,2000,19(2):139-142. 被引量:487
  • 2Minguez R, Ramos C, Barrientos S, et al. Postantibioctic effect of ciprofloxacin compared with that of five other guinolones[J]. Chemotherapy, 1991,37(6):420-421.

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