摘要
本文分析了99例氨苄青霉素静脉输入处方,表明氨苄青霉素在单一输液中应用为多,其中以10%葡萄糖、0.9%氯化钠及5%葡萄糖注射液为常用。探讨了氨苄青霉素在这三种输液中的稳定性,观察存放时间(0—24小时)对效价、pH 值及外观性状的影响。结果表明氨苄青霉素效价随时间延长而逐渐下降, 在10%葡萄糖及5%葡萄糖中效价下降显著;pH 值变化不大;外观性状无变化。据此提示临床应提倡氨苄青霉素与0.9%氯化钠配伍,如必需用葡萄糖输液制剂也应在2小时内快速完成静滴为宜。
It is analyzed in this article that 99 cases of prescriptions of vein transfusion of ampicillum.It shows that ampicillum is often used with alone solution such as 10% G.S,0.9% NaCl and 5% G.S.It is up to 66.7% of the use.The authors have discussed the stability of the ampicillum in the three solutions and observed the effect of store-time (0-24 hours)on efficacy,PH and out-side disposition.It indicates that the efficacy is reduced with the store-time increased,the PH value change is not obvious and out-side disposition has no change.The authors suggest that ampicillum is compatible with 0.9% NaCl in clinical application.If it is necessary to use ampicillum with G.S vein transfusion,the vein transfusion must be finished rapidly within 2 hours.
