摘要
Objective:Confirming complete neointimal coverage after implantation of drug-eluting stent(DES)is clinically important because incomplete stent coverage is maybe responsible for late thrombosis and sudden cardiac death.Optical coherence tomography(OCT)is a high-resolution(≈10 μm)imaging technique capable of detecting a thin layer of neointimal hyperplasia(NIH)inside DES.Helios stent system(KinheIy Bio-tech Co(Shenzhen).Ltd)is a new generation of sirolimus eluting stents.Methods:Motorized optical coherence tomographic pullback was performed at 9-month follow-up to examine consecutive Helios stent mplantations in 10 patients.NIH thickness inside each strut and NIH area percentage inside each cross-section were measured.Results:In total,2063 struts in 296 mm stented segments were analyzed.Overall,NIH thickness were(95.7±66.62)μm,rates of exposed struts was 60.2% and the average NIH area percentage was 5.0618% ± 5.6625%.Conclusion:Our study suggests that dual antiplatelet therapy after Helios stent implantation must be continued at least 9months after DES implantation.
Objective:Confirming complete neointimal coverage after implantation of drug-eluting stent(DES)is clinically important because incomplete stent coverage is maybe responsible for late thrombosis and sudden cardiac death.Optical coherence tomography(OCT)is a high-resolution(≈10 μm)imaging technique capable of detecting a thin layer of neointimal hyperplasia(NIH)inside DES.Helios stent system(KinheIy Bio-tech Co(Shenzhen).Ltd)is a new generation of sirolimus eluting stents.Methods:Motorized optical coherence tomographic pullback was performed at 9-month follow-up to examine consecutive Helios stent mplantations in 10 patients.NIH thickness inside each strut and NIH area percentage inside each cross-section were measured.Results:In total,2063 struts in 296 mm stented segments were analyzed.Overall,NIH thickness were(95.7±66.62)μm,rates of exposed struts was 60.2% and the average NIH area percentage was 5.0618% ± 5.6625%.Conclusion:Our study suggests that dual antiplatelet therapy after Helios stent implantation must be continued at least 9months after DES implantation.
出处
《心肺血管病杂志》
CAS
2010年第S1期79-80,共2页
Journal of Cardiovascular and Pulmonary Diseases
基金
北京市科委高科技战略主题计划资助项目(D0906006040191)
北京市科技新星计划资助项目(2007A001)
