摘要
目的:探讨胺碘酮联合索他洛尔救治快速室上性心律失常的临床疗效。方法:选取2010年8月至2013年10月广州市荔湾区第二人民医院收治的128例快速室上性心律失常患者作为研究对象,随机分为对照组(胺碘酮)和观察组(胺碘酮+索他洛尔),每组各64例。观察两组患者的临床疗效及药物起效时间、治疗后心率、窦性心律复转率等指标。结果:观察组有效率为94%(60/64),高于对照组的80%(51/64);观察组药物起效时间及治疗后心率均显著低于对照组;窦性心律复转率明显高于对照组;上述指标比较,差异均有统计学意义(P<0.05)。结论:胺碘酮联合索他洛尔治疗快速室上性心律失常起效快、效果好。
Objective:To investigate the clinical utility of amiodarone combined with sotalol for rapid supraventricular arrhythmia(RSA).Methods:Between August 2010 and October 2013,we recruited 128 patients with RSA from Second People' s Hospital of Liwan District,Guangzhou.Patients were randomly assigned to be treated with oral amiodarone therapy alone(control group,n =64) or in combination with sotalol(treatment group,n = 64).The efficacy in terms of time of onset,post-treatment heart rate and,the rate of sinus complex transfer were assessed.Results:The effective rate was higher in treatment group(93.75%(60/64) vs.79.69%(51/64)) than control group(P<0.05).The treatment group was associated with a shorter time of onset,a lower level of heart rate and higher rate of sinus rhythm(all P<0.05).Conclusion:Amiodarone combined with sotalol is characterized by an ideal efficacy in patients with RSA.
出处
《广州医学院学报》
2014年第1期22-24,共3页
Academic Journal of Guangzhou Medical College
