摘要
目的探讨胃大部切除不同重建术式对胃癌伴2型糖尿病的影响。方法选择术前3组在葡萄糖耐量试验空腹血糖、负荷后2h血糖、糖化血红蛋白比较无统计学差异(P>0.05)的33例本院手术治疗的胃癌合并2型糖尿病患者,分为毕Ⅰ式组13例、毕Ⅱ式组12例、Roux-en-y组8例。术前收集主要临床资料,术后3个月随访口服葡萄糖耐量试验空腹及负荷后血糖值、糖化血红蛋白等。结果术后3个月随访时,毕Ⅱ式组与Roux-en-y组OGTT空腹血糖(χ2=6.472,P=0.005)、OGTT负荷后2h血糖值(χ2=3.431,P=0.041)、糖化血红蛋白(χ2=5.456,P=0.009)均显著降低。结论胃癌合并糖尿病患者在消化道重建术后部分可得缓解,并且采用毕Ⅱ式或Roux-en-y吻合术对胃癌合并糖尿病患者可能更适合。
Objective To investigate the impact on different type of gastrectomy reconstruction in patients with gastric cancer and diabetes.Methods 33 cases of gastric cancer and type 2 diabetes who were undergoing surgical treatment in our hospital were collected and divided into BillrothⅠgroup of 13 cases,Billroth Ⅱ group of 12 cases and Roux-en-y group of 8 cases.Their preoperative clinical data and follow-up after 3 months data was collected.OGTT fasting and challenged blood glucose levels and glycosylated hemoglobin were tested.Results OGTT fasting plasma glucose and challenged glucose after 2 hours,glycosylated hemoglobin were no significant different(P>0.05) before surgery.When in follow-up after 3 months,the number of cases under diabetes standards was significantly reduced(χ2=4.818,P=0.090)in the Billroth Ⅱ group and Roux-en-y group compared with BillrothⅠgroup.The OGTT fasting glucose(χ2=6.472,P=0.005),OGTT challenged 2h glucose value(χ2=3.431,P=0.041) and glycosylated hemoglobin(χ2=5.456,P=0.009) were significantly lower.Conclusion Some of the patients with gastric cancer and diabetes mellitus in the digestive tract reconstruction could be alleviated.Billroth II or Roux-en-y anastomosis for gastric cancer patients with diabetes mellitus may be more suitable.
出处
《江西医药》
CAS
2013年第3期192-194,共3页
Jiangxi Medical Journal
关键词
糖尿病
胃癌
胃大部切除术
空腹血糖
糖化血红蛋白
Diabetes
Gastric cancer
Partial gastric resection
Fasting plasma glucose
Glycosylated hemoglobin
