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舒芬太尼加小剂量氯胺酮静脉镇痛观察

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摘要 氯胺酮是非竞争性N-甲基-D-天冬氨酸受体拮抗剂,临床上仅使用麻醉浓度1/5-1/10量,即可明显抑制该受体的活性,产生有效的镇痛作用,并且可增强阿片类药物对神经损害性疼痛的镇痛作用。但是临床上对氯胺酮用于术后镇痛的疗效及与镇痛药的协同作用意见不统一。本研究探讨小剂量氯胺酮对舒芬太尼静脉镇痛效果的影响,并对其安全性、有效性进行评价。
出处 《基层医学论坛》 2008年第26期801-802,共2页 The Medical Forum
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