摘要
目的比较苯那普利与卡维地洛治疗高血压的疗效和安全性。方法将129例原发性高血压患者随机分为苯那普利组65例(男42例,女23例,年龄55±9岁),用苯那普利5 mg~10mg,po,qd:卡维地洛组64例(男41例,女23例,年龄54±10岁),以卡维地洛10 mg~20 mg,po,Bid,2组疗程均为4wk。结果治疗4wk 后,两组血压下降差别均有非常显著意义(P<0.01);苯那普利组的总有效率为91%,卡维地洛组为92%,两组疗效差别无显著意义(P>0.05)。苯那普利与卡维地洛均无严重不良反应。结论苯那普利与卡维地洛治疗原发性高血压疗效均好。
Objective To compare the efficacy and safety of banazapril and carverdilol in treatingessential hypertension(E.H).Methods Patiems with EH(n=129) were randomly divided into 2 groups.Banazapril group(M42,F23;age 55a±9a)was treated with banazapril 5~10 mg,po,qd for 4wk. carverdilol group(M41,F23;age 54a±10a) was treated with carverdilol 10 mg~20 mg,po,Bid.Result After 4 wk of therapy,both groups showed reduction of blood pressure(P<0.01);The total response rates of banazapriil and caxverdilol were 90% and 92% respectively(P>0.05).The adverse reactione of 2 groups were mild.Conclusion Both banazapril and carverdilol are effective and safe treating EH.
出处
《基层医学论坛》
2003年第5期386-388,共3页
The Medical Forum