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光动力学疗法的免疫效应机制研究进展 被引量:8

Immunosuppression Induced by Photodynamic Therapy:a Research Progress
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摘要 光动力学疗法已经在临床上用于治疗许多肿瘤性和非肿瘤性疾病。目前的研究结果表明光动力效应与炎症和免疫反应密切相关,它在疾病的长期控制中发挥着重要作用。该效应对免疫系统的影响非常复杂,它既能促进又能抑制免疫反应,其优势效应的产生与许多因素有关。本文阐述了光动力学疗法对免疫系统的影响,并探讨了它在疾病治疗中的重要意义。 Photodynamie therapy is an approved therapeutic modality for several types of tumors as well as non-malignant diseases.However,ac- cumulating evidence indicates these effects are also mediated by inflammatory and immune responses.It is important for achieving long- term disease control.PDT can not only activate but also suppress the immune response depending on several variables.This review summarizes the influence of PDT on the immune response and discusses its importance in the management of human diseases.
出处 《中国激光医学杂志》 CAS CSCD 2006年第5期330-335,共6页 Chinese Journal of Laser Medicine & Surgery
关键词 光动力学疗法 炎症反应 免疫效应 Photodynamic therapy Inflammatory response Immune response
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