摘要
研究羟基磷灰石/高密度聚乙烯(HA/HDPE)纳米复合人工听小骨的生物相容性。以目前临床应用的钛合金植入材料为对照,将HA/HDPE纳米复合材料浸提液与L929细胞混合培养后,用流式细胞仪测定其S期的细胞百分比;将两种材料分别植入动物体内,通过组织病理学方法评价其生物相容性。统计学分析两组数据无明显差异,结果表明,HA/HDPE纳米复合人工听小骨具有良好的生物相容性及临床应用前景。
This study was aimed to evaluate the biocompatibility of Hydroxyapatite/High density polyethylene (HA/HDPE) nano-composites artificial ossicle. The percentage of S-period cells were detected by flow cytometry after L929 cells being incubated with extraction of the HA/HDPE nano-composites;the titanium materials for clinical application served as the contrast. In addition, both materials were implanted in animals and the histopathological evaluations were conducted. There were no statistically significant dif...
出处
《生物医学工程学杂志》
EI
CAS
CSCD
北大核心
2008年第3期607-610,共4页
Journal of Biomedical Engineering
基金
863基金资助项目(2003AA302210)
湖南省自然科学基金资助项目(04JJ3083)
