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强直性脊柱炎的临床、实验室与放射学关系的探讨 被引量：4

The research of the relationship between clinic,Lab and radiology change of AS
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摘要 目的 :探讨强直性脊柱炎 (AS)临床、实验室及放射学改变之间的关系。方法 :确诊为AS的患者 35例 ,测定其ESR及IgG、IgM、IgA和HLA -B2 7,并同时做骶髂关节平片和CT扫描 ,研究其相互关系。结果 :本组双侧骶髂关节受累者达 10 0 %。HLA -B2 7阳性率 90以上。 35例中 ,10例平片诊断Ⅰ～Ⅱ级 ,CT诊断Ⅱ～Ⅲ级 ;15例平片诊断Ⅱ～Ⅲ级 ,CT诊断Ⅲ～Ⅳ级。AS骶髂关节炎分级越高 ,其临床表现、免疫学指标均加重 ,红细胞沉降率在Ⅱ～Ⅲ级中最快。结论 :AS与HLA -B2 7高度相关。AS患者骶髂关节炎分级基本可反映病情程度。两性AS患者存在差异 ,女性病情轻 ,预后好。 Objective:To study the relationship between the clinic,Lab and radiology change of AS.Method:To assay ESR,IgG,IgM,IgA and HLA-B27,to make sacroiliac articulation X-rays and CT scan on 35 cases diagnosed.And to analyze their interrelation.Result:The percentage of both side sacroiliac articulation affected by AS of 35 cases was as high as 100%.10 cases were graded by X-rays to Ⅰ～Ⅱ guade,but were Ⅱ～Ⅲ grade by CT scan;15 cases were graded to Ⅱ～Ⅲ grade by X-rays,while wereⅢ～Ⅳgrade by CT scan.The higher the ...
作者 刘海燕 肖丽 郭冬梅 艾群 姜国民
机构地区 大连医科大学第二临床学院风湿科 大连医科大学第二临床学院放射科 大连医科大学第二临床学院中医科
出处 《大连医科大学学报》 CAS 2001年第2期102-104,共3页 Journal of Dalian Medical University
关键词 强直性脊柱炎 骶髂关节 CT X线平片 ankylosing spondylitis sacriliac articulation CT X-rays
分类号 R593.23 [医药卫生—内科学]
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参考文献5

  • 1[1]Dawkins RL.Prevalence of AS and radiological abnormalities of the sacroiliac joints in HLA -B27 positive individuals(letter)[J].Rheumatol, 1981,8:1025.
  • 2曾庆馀 蒋明 等.骨性关节炎.风湿病学[M].北京:科学出版社,1996.1368-1387.
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  • 4[4]陈贤.实用放射学[M].北京:人民卫生出版社,1997.1024-1026.
  • 5[6]Kerr R, Resnick D.Radiology of the seronegative spondylo-arthropathies [J].Clinics Rhedm Dis,1985,11:113.The research of the relationship between clinic,Lab andradiology change of AS

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同被引文献96

  • 1陈宇明,邹和建,张炯,徐黎明,关明.应用SYBR GreenI荧光聚合酶链反应检测人类白细胞抗原-B27[J].中华风湿病学杂志,2005,9(2):97-99. 被引量：3
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  • 7Liu S Q, Yu H C, Gong Y Z, et al. Quantitative measurement of HLA- B27 rnRNA in patients with ankylosing spondylitis-correlation with clinical activity[J]. Journal of Rhettmatology, 2006, 33: 1128.
  • 8Niedermarm G, Immunological functions of the proteasome [J]. Curr Top Microbiol Immunol, 2002, 268: 91.
  • 9Wilson A G, Symons J A, McDowell T L, et al. Effects of a polymorphism in the human tumor necrosis factor alpha promotet on transcriptional activation[J]. Proc Natl Acad Sci USA, 1997, 94(7): 3195.
  • 10Vazquez-Del M M, Gareia-Gonzalez A, Muoz-Valle J F, et al. Interleukin lbeta (IL-1beta), IL-10, tumor necrosis factor-alpha, and cellular proliferation index in peripheral blood mononuelear cells in patients with ankylosing spondylitis[J]. J Rheurnatol, 2002, 29(3): 522.

引证文献4

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大连医科大学学报
2001年 第2期

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