摘要
目的探讨注射药物信息化管理改善维持性血液透析患者贫血的效果。方法回顾性分析上海交通大学医学院附属第六人民医院血液净化中心注射药物信息化管理(2020年4月在原信息化系统基础上开发)前后6个月维持性血液透析患者血红蛋白、铁蛋白、转铁蛋白饱和度达标率及心血管事件发生率的变化。2019年10月至2020年3月为信息化管理前的对照阶段,2020年4至9月为信息化管理后的研究阶段。结果对照阶段纳入患者285例,男190例,女95例,年龄(62.4±13.2)岁;研究阶段纳入患者278例,男193例,女85例,年龄(62.8±13.2)岁。与对照阶段相比,研究阶段患者血红蛋白[47.8%(797/1668)比40.2%(687/1710),P<0.001]、铁蛋白[39.0%(217/556)比31.2%(178/570),P=0.006]及转铁蛋白饱和度[64.7%(360/556)比58.6%(334/570),P=0.034]达标率均较高。研究阶段心血管事件发生率为11.2%(31/278),低于对照阶段的16.5%(47/285),差异有统计学意义(P=0.043)。结论血液净化中心采用注射药物信息化管理有利于改善维持性血液透析患者贫血状况。
Objective To investigate the effect of information management of intravenous drugs on anemia in maintenance hemodialysis patients.Methods The information management of intravenous drugs was a management system developed by the Hemodialysis Center of Shanghai Jiao Tong University School of Medicine Affiliated Sixth People′s Hospital in April 2020.The parameters six months before and after the use of the information management system were retrospectively collected and compared,including the rate of reaching the standard of hemoglobin,ferritin,transferrin saturation rate and the incidence of cardiovascular events.Specifically,the control stage was from October 2019 to March 2020,which was before the use of information management,and the study stage was from April to September 2020,which was after the use of information management.Results There were 285 patients(190 males and 95 females)included in the control stage,with an average age of(62.4±13.2)years,while 278 patients(193 males and 85 females)were included in the study stage,with an average age of(62.8±13.2)years.Compared with the control stage,the rate of reaching the standard of hemoglobin[47.8%(797/1668)vs 40.2%(687/1710),P<0.001],ferritin[39.0%(217/556)vs 31.2%(178/570),P=0.006],and transferrin saturation[64.7%(360/556)vs 58.6%(334/570),P=0.034]increased in the study stage.The incidence of cardiovascular events in the study stage was 11.2%(31/278),which was significantly lower than that in the control stage[16.5%(47/285)](P=0.043).Conclusion The information management of intravenous drugs in the hemodialysis center may help improve the anemia status in maintenance hemodialysis patients.
作者
盛晓华
俞岗
张妮娜
何俐
尹建永
林文军
王振宏
程东生
吴险峰
汪年松
Sheng Xiaohua;Yu Gang;Zhang Nina;He Li;Yin Jianyong;Lin Wenjun;Wang Zhenhong;Cheng Dongsheng;Wu Xianfeng;Wang Niansong(Department of Nephrology,Shanghai Jiao Tong University School of Medicine Affiliated Sixth People′s Hospital,Shanghai 200233,China)
出处
《中华医学杂志》
CAS
CSCD
北大核心
2023年第14期1055-1059,共5页
National Medical Journal of China
基金
国家自然科学基金(81870504)
上海市领军人才计划(058)
关键词
肾透析
贫血
信息化管理
Renal dialysis
Anemia
Information management
