摘要
流行性感冒病毒和新型冠状病毒感染是重症监护病房(ICU)重症患者发生侵袭性真菌病(IFD)的危险因素。IFD中丝状真菌病占比较高且病死率很高。丝状真菌病的诊治面临诸多挑战,及时发现、尽早治疗是降低病死率的关键因素。本文将就重症患者发生丝状真菌病的最新流行病学数据和危险因素、目前的诊断标准和难点,以及目前国际上多个临床指南推荐的治疗方案展开讨论,以期为重症患者丝状真菌病的诊断和治疗提供一些参考。
Influenza and coronavirus disease 2019 are independent risk factors for the development of invasive fungal disease(IFD)in critically ill patients in the intensive care unit.IFD,particularly mold infections,have a high mortality rate.The diagnosis and treatment of mold infections is challenging,and early detection and timely treatment are crucial in reducing the mortality of IFD.This review will summarize the latest epidemiology and risk factors for the development of mold infections in critically ill patients,current diagnostic criteria and challenges,as well as the treatment strategies recommended by the international clinical guidelines,aiming to provide some references for the diagnosis and treatment of mold infections in critically ill patients in clinical practice.
作者
郑悦
李文雄
Zheng Yue;Li Wenxiong(SICU,Beijing Chaoyang Hospital,Capital Medical University,Beijing 100020,China)
出处
《中华医学杂志》
CAS
CSCD
北大核心
2023年第39期3077-3082,共6页
National Medical Journal of China
基金
首都卫生发展科研专项(首发2020-2-1061)
关键词
重症监护
丝状真菌病
诊治
挑战
Intensive care
Filamentous fungal infection
Diagnosis and treatment
Challenges
