摘要
目的:研究重叠综合征(OS)与阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者在肺功能上的变化差异及夜间低氧血症的关系。方法选择确诊为重叠综合征(OS)患者25例,确诊为阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者25例,分别查肺功能和血气分析及整夜多导睡眠仪监测。结果①OS组的最低 SaO2%低于单纯OSAHS组(P<0.05),Lat、AHI高于单纯 OSAHS组(P<0.05);②OS组 PaCO2高于单纯 OASHS组(P<0.05),而 PaO2及 SO2低于单纯 OSAHS组(P<0.05);③两组患者FVC%、FEV1%、FEV1/FVC%均低于单纯OSAHS组(P<0.05)。结论 OS患者较单纯OSAHS患者日间肺功能损害更严重,夜间低氧更明显。
Objective To explore the dif erence in pulmonary function between overlap syndrome(OS)and(OSAHS)sleep apnea hypopnea syndrome(OSAHS)patients.Methods 50 patients who were randomly recruited were divided into two groups,which contained 25 overlap syndrome patients and 25 patients OSAHS respectively.To compare the dif erence in polysomnography,pulmonary function tests and blood gas analysis.Results 1)The lowest SaO2 in the OS group were lower than that in the OSAHS group(P<0.05).Lat,AHI in OS group were higher than those in OSAHS group(P<0.05).2)PaCO2 in OS group were higher than that in the OSAHS group(P<0.05)while PaO2,SO2 Were lower than those in OSAHS group(P<0.05).3)FVC%、FEV1%and FEV1/FVC%were lower than those in OSAHS group(P<0.05).The pulmonary function injury in the OS group were more serious than that in OSAHS group.Conclusion Hypoxemia in the night in the OS group were more obvious than that in that in OSAHS.
作者
赵丽
ZHAO Li(Tianjin Medical University,Tianjin 300070,China)
