期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

Baseline Characteristics and Treatment Patterns of the Patients Recruited to the China Registry of Hepatitis B 被引量：14

原文传递
导出
摘要 Background and Aims: Chronic hepatitis B virus(HBV)in-fection remains a major public health problem globally.Here,we describe the baseline characteristics and treatment pro-files of HBV-infected patients recruited to the China Registry of Hepatitis B.Methods: Inclusion criteria were patients with different stages of chronic HBV infection and complete key data.Exclusion criteria were patients with hepatocellular car-cinoma.The baseline clinical,laboratory and treatment pro-files were analyzed.Results: Finally,40,431 patients were included.The median age was 43 years,with 65.2%being men and 51.3%being positive for hepatitis B e antigen(HBeAg).The most common initial diagnosis was chronic hep-atitis B(81.0%),followed by cirrhosis(9.3%),inactive carrier of hepatitis B surface antigen(HBsAg)(6.7%),and immune tolerant phase of hepatitis B infection(3.0%).Among the 21,228 patients who were on treatment,88.0%,10.0%and 2.0%received nucleos(t)ide analogues(NAs),interferon or combination of NAs and interferon,respectively.The propor-tion of patients who received preferred NAs(entecavir or te-nofovir disoproxil fumarate)had increased from 13.5%in 2003 to 79.7%in 2016.Conclusions: We concluded that middle-aged men accounted for most of the patients with chronic hepatitis B in this cross-sectional study.About half of the patients were HBeAg-positive.NAs were the most com-monly used therapy,and use of the preferred NAs had steadily increased in the past decade.
作者 Shan Shan Hong You Junqi Niu Jia Shang Wen Xie Yuexin Zhang Xun Li Hong Ren Hong Tang Huiguo Ding Xihong Wang Yuemin Nan Xiaoguang Dou Tao Han Lingyi Zhang Xiaoqing Liu Cunliang Deng Jilin Cheng Xiaozhong Wang Qing Xie Shumei Lin Yan Huang Youqing Xu Yong Xiong Wu Li Xuebing Yan Hongxin Piao Wenxiang Huang Qinghua Lu Weijin Gong Shiping Li Xiaoxuan Hu Xiaolan Zhang Shourong Liu Yufang Li Dongliang Yang Hai Li Caixia Yang Mingliang Cheng Liaoyun Zhang Huanwei Zheng Xinhua Luo Feng Lin Lei Wang Guanghua Xu Xiaoyuan Xu Lai Wei Jinlin Hou Zhongping Duan Hui Zhuang Xizhong Yang Yuanyuan Kong Jidong Jia the CR-HepB study group,Beijing,China
机构地区 Liver Research Center Department of Hepatology Department of Infectious Diseases Center of Liver Diseases Department of Infectious Diseases Department of General Surgery Department of Infectious Diseases Center of Infectious Diseases Department of Gastroenterology and Hepatology Center of Infectious Diseases Department of Traditional and Western Medical Hepatology Department of Infectious Diseases Department of Hepatology Department of Hepatology Department of Infectious Diseases Department of Infectious Diseases Department of Gastroenterology Department of Hepatology Department of Infectious Diseases Department of Infectious Diseases Department of Infectious Diseases Department of Digestive System Department of Infectious Diseases Department of Infectious Diseases Department of Infectious Diseases Department of Infectious Diseases Department of Infectious Diseases Department of Hepatology Department of Infectious Diseases Department of Hepatopancreatobiliary Surgery Department of Hepatology Department of Gastroenterology Department of Hepatology Department of Infectious Diseases Department of Infectious Diseases Department of Hepatopancreatobiliary and Splenic Medicine Department of Infectious Diseases Department of Infectious Diseases Department of Infectious Diseases Department of Infectious Diseases Department of Infectious Diseases Department of Infectious Diseases Department of Infectious Diseases Department of Infectious Diseases Department of Infectious Diseases Peking University Hepatology Institute Institute of Hepatology and Department of Infectious Disease Artificial Liver Center Department of Microbiology and Infectious Disease Center The China Foundation of Hepatitis Prevention and Control Center for Clinical Epidemiology and EBM 不详
出处 《Journal of Clinical and Translational Hepatology》 SCIE 2019年第4期322-328,共7页 临床与转化肝病杂志（英文版）
关键词 Hepatitis B TREATMENT REGISTRY
分类号 R51 [医药卫生—内科学]
  • 相关文献

参考文献1

二级参考文献16

  • 1Chinese Society of Hepatology,Chinese Medical Association and Chinese Society of Infectious Diseases,Chinese Medical Association.Guideline on prevention and treatment of chronic hepatitis B in China (2005)[J].Chinese Medical Journal,2007(24):2159-2173. 被引量：46
  • 2European Association for the Study of the Liver.EASL Clinical Practice Guidelines: Management of chronic hepatitis B virus infection[J]. Journal of Hepatology . 2012 (1)
  • 3Xiaofeng Liang,Shengli Bi,Weizhong Yang,Longde Wang,Gang Cui,Fuqiang Cui,Yong Zhang,Jianhua Liu,Xiaohong Gong,Yuansheng Chen,Fuzhen Wang,Hui Zheng,Feng Wang,Jing Guo,Zhiyuan Jia,Jingchen Ma,Huaqing Wang,Huiming Luo,Li Li,Shuigao Jin,Stephen C. Hadler,Yu Wang.Epidemiological serosurvey of Hepatitis B in China—Declining HBV prevalence due to Hepatitis B vaccination[J].Vaccine.2009(47)
  • 4Sang Hoon Ahn,Henry L. Y. Chan,Pei-Jer Chen,Jun Cheng,Mahesh K. Goenka,Jinlin Hou,Seng Gee Lim,Masao Omata,Teerha Piratvisuth,Qing Xie,Hyung Joon Yim,Man-Fung Yuen.Chronic hepatitis B: whom to treat and for how long? Propositions, challenges, and future directions[J].Hepatology International.2010(1)
  • 5Uchenna H. Iloeje,Hwai–I. Yang,Jun Su,Chin–Lan Jen,San–Lin You,Chien–Jen Chen.Predicting Cirrhosis Risk Based on the Level of Circulating Hepatitis B Viral Load[J]. Gastroenterology . 2006 (3)
  • 6Anna S. F. Lok,Brian J. McMahon.??Chronic hepatitis B: Update 2009(J)Hepatology . 2009 (3)
  • 7Yun-Fan Liaw,Jia-Horng Kao,Teerha Piratvisuth,Henry Lik Yuen Chan,Rong-Nan Chien,Chun-Jen Liu,Ed Gane,Stephen Locarnini,Seng-Gee Lim,Kwang-Hyub Han,Deepak Amarapurkar,Graham Cooksley,Wasim Jafri,Rosmawati Mohamed,Jin-Lin Hou,Wan-Long Chuang,Laurentius A.L.Asian-Pacific consensus statement on the management of chronic hepatitis B:a 2012 update. Hepatol Int . 2012
  • 8Chen Chien-Jen,Yang Hwai-I,Su Jun,Jen Chin-Lan,You San-Lin,Lu Sheng-Nan,Huang Guan-Tarn,Iloeje Uchenna H.Risk of hepatocellular carcinoma across a biological gradient of serum hepatitis B virus DNA level. JAMA : the journal of the American Medical Association . 2006
  • 9Chao Jonathan,Chang Ellen,So Samuel.Hepatitis B and liver cancer knowledge and practices among healthcare and public health professionals in China: a cross-sectional study. BMC Public Health . 2010
  • 10Lin-Hong Ning,Jia Hao,Zhong-Li Liao,Yuan-Yuan Zhou,Hong Guo,Xiao-Yan Zhao.??A survey on the current trends in the management of hepatitis B in China(J)European Journal of Gastroenterology & Hepatology . 2012 (8)

共引文献3

同被引文献53

引证文献14

二级引证文献83

Journal of Clinical and Translational Hepatology
2019年 第4期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部