摘要
目的对1996至2004年全国出生缺陷监测的联体双胎进行流行病学分析,了解其发生水平、分布特征和影响因素等状况.方法采用分层随机抽样的方法,对全国450多所县级或县级以上医院进行监测,监测对象为孕28周至产后7d的围产儿,包括活产、死胎和死产.结果1996至2004年共监测围产儿数4282536例,发现联体双胎122例,全国平均发生率为0.28/万.其中城镇发生率为0.20/万,农村发生率为0.47/万,农村发生率明显高于城镇;女性联体双胎发生率为0.36/万,男性联体双胎发生率为0.17/万;联体双胎的围产期死亡率为82.6%;产前确诊率53.7%.结论联体双胎是一种围产期死亡率很高的畸形,我国为联体双胎高发国家,且城乡发生率和男女发生率间存在明显差异,应加强围产期管理和提高产前诊断水平.
Objective To understand the trend of incidence of conjoined twins and its epidemiological characteristics in.China during 1996 to 2004 Methods A descriptive epidemiology of conjoined twinning in China from 1996 to 2004 was investigated by uaing data from National Center for Birth Defects Monitoring Program(NCBDMP).Data were collected from more than 400 hopital-based units involved in the program.The monitored subjects were the hospitalized births from 28 weeks gestation to a period within 7 days after delivery.Results 122 conjoined twins were found in 4282536 births with an incidence rate of 0.28 per 10000.Incidence of conjoined twins was 0.20 per 10000 and 0.47 per10000 in the rural and urban areas,respectively,and the statistical significant difference(P<0.05)was observed.,Incidence of conjoined twins was for0.17 per 10000 and 0.36 per 10000 in boys and gils,respectively.Conjoined twins were more common among females than males,the live-bom rate was 41.32%,and the perinatal mortality was 82.6%.53.7%conjoined twins can be disgnosed prenatally.Conclusion The results indicate that the incidence of conjoined twins in China is higher than that in Western countries.It is necessary to improve the prenatal diagnostic techniques and management
作者
唐莹
朱军
周光萱
代礼
王艳萍
梁娟
TANG Ying;ZHU Jun;ZHOU Guang-xuan;DAI Li;WANG Yan-ping;LIANG Juan(National Center for Birth Defects Monitoring,the West China Second Hospital,Sichuan University,Chengdu 610041,China)
出处
《中华预防医学杂志》
CAS
CSCD
北大核心
2007年第S01期146-149,共4页
Chinese Journal of Preventive Medicine
关键词
双生
联体
围产期学
流行病学研究
Twins,conjoined
Perinatology
Epidemiologic studies
