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经尿道前列腺钬激光剜除术对前列腺增生患者尿动力学参数及生活质量的影响

Effect of Transurethral Holmium Laser Enucleation of Prostate on Urodynamic Parameters and Quality of Life in Patients with Benign Prostatic Hyperplasia
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摘要 目的分析经尿道前列腺钬激光剜除术(HoLEP)对前列腺增生(BPH)患者的影响。方法选取2021年6月—2023年6月东营市人民医院收治的80例BPH患者为研究对象,按随机数字表法将其分为对照组及观察组,每组40例。对照组行经尿道前列腺电切术(TURP)治疗,观察组行HoLEP治疗。对比两组患者的围术期指标、症状严重程度、尿动力学参数、生活质量及并发症发生情况。结果观察组的术中出血量为(38.62±2.59)mL,少于对照组的(62.26±5.37)mL,手术时间为(91.58±7.15)min,长于对照组的(74.63±5.39)min,住院时间为(6.35±1.25)d,短于对照组的(8.21±1.69)d,组间差异有统计学意义(P<0.05)。术后,观察组的国际前列腺症状量表评分为(8.43±1.21)分,低于对照组的(11.35±1.59)分,差异有统计学意义(P<0.05)。术后,观察组的最大尿流率为(24.57±3.46)m L/s,快于对照组的(20.49±2.38)mL/s,残余尿量为(20.34±1.96)mL,少于对照组的(25.60±2.59)mL,膀胱顺应性为(26.38±4.27)mL/cmH_(2)O,高于对照组的(20.49±3.18)mL/cmH_(2)O,组间差异有统计学意义(P<0.05)。术后,观察组的生活质量综合评定问卷中的社会功能、心理功能、躯体功能、物质生活状态评分分别为(78.93±4.65)分、(79.96±4.15)分、(80.49±4.34)分、(82.34±4.49)分,均高于对照组的(70.59±4.21)分、(69.83±3.26)分、(71.36±3.63)分、(73.85±3.52)分,组间差异有统计学意义(P<0.05)。观察组的并发症发生率为5.00%,低于对照组的20.00%,差异有统计学意义(P<0.05)。结论HoLEP具有创伤小、恢复快等优势,可有效减轻BPH患者的症状,改善其尿动力学,提高其生活质量,且并发症少,值得临床推广应用。 Objective To analyze the effect of transurethral holmium laser enucleation of prostate(HoLEP)on patients with benign prostatic hyperplasia(BPH).Methods 80 patients with BPH admitted to Dongying People's Hospital from June 2021 to June 2023 were selected as the research objects and were divided into a control group and an observation group according to random number table method,with 40 cases in each group.The control group received transurethral resection of prostate(TURP)treatment,and the observation group received HoLEP treatment.The perioperative indexes,symptom severity,urodynamic parameters,quality of life and complications were compared between the two groups.Results The intraoperative blood loss in the observation group was(38.62±2.59)mL,less than(62.26±5.37)mL in the control group,the operation time was(91.58±7.15)min,longer than(74.63±5.39)min in the control group,and the hospital stay was(6.35±1.25)d,shorter than(8.21±1.69)d in the control group,and the differences between the groups were statistically significant(P<0.05).After operation,the international prostate symptom score in the observation group was(8.43±1.21)points,which was lower than(11.35±1.59)points in the control group,and the difference was statistically significant(P<0.05).After operation,the maximum urine flow rate in the observation group was(24.57±3.46)mL/s,which was faster than(20.49±2.38)mL/s in the control group,and the post-void residual urine volume was(20.34±1.96)mL,which was less than(25.60±2.59)mL in the control group,the bladder compliance was(26.38±4.27)mL/cmH_(2)O,which was higher than(20.49±3.18)mL/cmH_(2)O in the control group,and the differences between the groups were statistically significant(P<0.05).After operation,the scores of social function,psychological function,physical function and material life of the Generic Quality of Life Inventory-74 in the observation group were(78.93±4.65)points,(79.96±4.15)points,(80.49±4.34)points,(82.34±4.49)points,respectively,which were higher than(70.59±4.21)points,(69.83±3.26)points,(71.36±3.63)points,(73.85±3.52)points in the control group,and the differences between the groups were statistically significant(P<0.05).The incidence of complications in the observation group was 5.00%,which was lower than 20.00%in the control group,and the difference was statistically significant(P<0.05).Conclusion HoLEP has the advantages of less trauma and quick recovery,which can effectively reduce the symptoms of BPH patients,improve their urodynamics,improve their quality of life,and have fewer complications,which is worthy of clinical promotion.
作者 袁智 柳小丽 YUAN Zhi;LIU Xiaoli(Department of Urology,Dongying People's Hospital,Dongying Shandong,257091,China;Department of Hospital Infection Control,Dongying People's Hospital,Dongying Shandong,257091,China)
出处 《反射疗法与康复医学》 2024年第7期137-140,共4页 Reflexology And Rehabilitation Medicine
关键词 前列腺增生 经尿道前列腺钬激光剜除术 尿动力学参数 生活质量 Benign prostatic hyperplasia Transurethral holmium laser enucleation of prostate Urodynamic parameters Quality of life
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