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加味桂枝芍药知母汤联合穴位注射治疗椎动脉型颈椎病气滞血瘀证的疗效观察 被引量:15

Clinical Observation on Jiawei Guizhi Shaoyao Zhimu Decoction( 加味桂枝芍药知母汤) andAcupoint Injection in Treatment of Cervical Spondylosis of Vertebral Artery Type withQi Stagnation and Blood Stasis Syndrome
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摘要 目的研究加味桂枝芍药知母汤联合穴位注射治疗椎动脉型颈椎病气滞血瘀证的疗效。方法收集所有2018年9月—2019年9月于该院颈肩门诊收治的椎动脉型颈椎病气滞血瘀证患者113例,随机分为对照组(n=56)及观察组(n=57),对照组单纯给予加味桂枝芍药知母汤及基础治疗,观察组给予上述治疗及穴位注射治疗,均治疗4周。对比两组患者治疗前后颈椎病临床评价量表(CASCS)评分、中医证候积分变化;采用全自动血流变快测仪检测两组患者治疗前后高低切血液黏度、血浆黏度及纤维蛋白原水平,对比两组患者治疗效果,研究加味桂枝芍药知母汤联合穴位注射治疗椎动脉型颈椎病气滞血瘀证的疗效。结果治疗前,两组患者CASCS评分差异无统计学意义(P>0.05),治疗后两组患者CASCS评分均高于治疗前,且治疗后观察组CASCS评分高于治疗后对照组评分,差异有统计学意义(P<0.05)。治疗前,两组患者中医证候积分差异无统计学意义(P>0.05),治疗后两组患者眩晕、肢体麻木及头痛积分均低于治疗前,且治疗后观察组眩晕、肢体麻木及头痛积分低于治疗后对照组积分,差异有统计学意义(P<0.05)。治疗前,两组患者高低切血液黏度、血浆黏度及纤维蛋白原水平差异无统计学意义(P>0.05),治疗后两组患者高低切血液黏度、血浆黏度及纤维蛋白原水平均低于治疗前,且治疗后观察组高低切血液黏度、血浆黏度及纤维蛋白原水平低于治疗后对照组,差异有统计学意义(P<0.05)。治疗后,观察组患者疗效的总有效率为91.23%(52/57),明显高于对照组的76.79%(43/56),差异有统计学意义(P<0.05)。结论加味桂枝芍药知母汤联合穴位注射治疗椎动脉型颈椎病气滞血瘀证疗效较好,可活血化瘀,提高患者生活质量,应在临床广泛应用。 Objective To study the curative effect of Jiawei Guizhi Shaoyao Zhimu Decoction(加味桂枝芍药知母汤)combined with acupoint injection on the syndrome of Qi stagnation and blood stasis of cervical spondylosis of vertebral artery type.Methods A total of 113 patients with Qi stagnation and blood stasis syndrome of cervical spondylosis of vertebral artery type admitted to Neck and Shoulder Clinic of our hospital from September 2018 to September 2019 were randomly divided into control group(n=56)and observation group(n=57).The control group was treated with Jiawei Guizhi Shaoyao Zhimu Decoction andbasic treatment,and the observation group was treated with the above treatment and acupoint injection for 4 weeks.The clinical evaluation scale of cervical spondylosis(CASCS)score and TCM syndrome score before and after treatment were compared between the two groups.The blood viscosity,plasma viscosity and fibrinogen level of the two groups before and after treatment were measured by the automatic hemorheology fast measuring instrument,and the treatment effect of the two groups was compared to study the treatment effect of Jiawei Guizhi Shaoyao Zhimu Decoction combined with acupoint injection on cervical spondylosis of vertebral artery type with Qi stagnation.Results There was no significant difference between the two groups before treatment(P>0.05).After treatment,the scores of the two groups were higher than those before treatment,and the scores of the observation group after treatment were higher than those of the control group.The difference was statistically significant(P<0.05).Before treatment,there was no significant difference in TCM syndrome score between the two groups(P>0.05).After treatment,the scores of vertigo,limb numbness and headache in the two groups were lower than those before treatment,and the scores of vertigo,limb numbness and headache in the observation group were lower than those in the control group after treatment,and the difference was statistically significant(P<0.05).Before treatment,there was no significant difference between the two groups in high and low cut blood viscosity,plasma viscosity and fibrinogen level(P>0.05).After treatment,the high and low cut blood viscosity,plasma viscosity and fibrinogen level in the two groups were lower than that before treatment,and after treatment,the high and low cut blood viscosity,plasma viscosity and fibrinogen level in the observation group were lower than that in the control group(P<0.05).After treatment,the total effective rate of the observation group was 91.23%(52/57),significantly higher than 76.79%(43/56)of the control group.The difference was statistically significant(P<0.05).Conclusion Jiawei Guizhi Shaoyao Zhimu Decoction combined with acupoint injection is effective in the treatment of Qi stagnation and blood stasis syndrome of vertebral artery type cervical spondylosis,which can promote blood circulation and blood stasis,improve the quality of life of patients and should be widely used in clinic.
作者 李勃 LI Bo(Tianjin First Central Hospital,Chinese and Western Medicine,Tianjin 300221,China)
出处 《辽宁中医杂志》 CAS 2021年第7期113-116,共4页 Liaoning Journal of Traditional Chinese Medicine
关键词 加味桂枝芍药知母汤 穴位注射 椎动脉型颈椎病 气滞血瘀证 疗效 Jiawei Guizhi Shaoyao Zhimu Decoction(加味桂枝芍药知母汤) acupoint injection cervical spondylosis of vertebral artery type Qi stagnation and blood stasis syndrome curative effect
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