摘要
目的探讨急性单纯胼胝体梗死的临床特点。方法选择2010年1月-2018年12月本院2694例脑梗死患者中,经MRI确诊的16例急性单纯胼胝体梗死患者(单纯胼胝体梗死组)和同时期42例合并有颅内其他部位梗死的复合胼胝体梗死(复合胼胝体梗死组),比较两组的临床资料,包括一般资料、危险因素、临床症状及体征、影像学表现等,分析单纯胼胝体梗死患者临床特点。结果(1)急性单纯胼胝体梗死占同期脑梗死发生率的0.59%(16/2694),主要危险因素是高血压、糖尿病和高脂血症;病变血管以大脑前动脉最多见;临床以肢体瘫痪、认知障碍和精神行为异常为主要表现;(2)与复合胼胝体梗死组相比,单纯胼胝体梗死组中既往有脑梗死病史的占比少(31.3%vs 66.7%,P<0.05);从发病到就诊的时间长(68.3±12.7h vs 16.4±10.2h,P<0.05);肢体单瘫更多见(69.2%vs 28.0%,P<0.05),肢体肌力NIHSS评分低(1.6±0.4 vs 3.6±0.8,P<0.05);大脑中动脉受累的占比少(62.5%vs 90.5%,P<0.05);预后更好(93.8%vs 61.5%,P<0.05)。结论急性单纯胼胝体梗死发生率低,常伴有多种动脉硬化危险因素,以肢体单瘫、认知障碍和精神行为异常为主要表现,预后较好。
Objective To investigate the clinical characteristics of acute simple corpus callosum infarction.Methods From January 2010 to December 2018,2694 patients with cerebral infarction in our hospital,16 patients with acute simple corpus callosum infarction confirmed by MRI(simple corpus callosum infarction group)and 42 patients with complex corpus callosum infarction(compound corpus callosum infarction group)combined with other intracranial infarction at the same time were selected,and the clinical data of the two groups were compared.General data,risk factors,clinical symptoms and signs,imaging manifestations were analyzed in patients with simple corpus callosum infarction.Results①Acute simple corpus callosum infarction accounted for 0.59%(16/2694)of the incidence of cerebral infarction in the same period.The main risk factors were hypertension,diabetes mellitus and hyperlipemia.Arteriae cerebri anterior was the most common vascular lesions.Clinical manifestations were limb paralysis,cognitive impairment and abnormal mental behavior;②Compared with the compound corpus callosum infarction group,the simple corpus callosum infarction group had less history of cerebral infarction(31.3%vs 66.7%,P<0.05);the time from onset to treatment was longer(68.3±12.7 h vs 16.4±10.2 h,P<0.05);single limb paralysis was more common(69.2%vs 28.0%,P<0.05),and the NIHSS score of limb muscle strength was lower(1.6±0.4 vs 3.6±0.8,P<0.05);the proportion of middle cerebral artery involvement was less(62.5%vs 90.5%,P<0.05);the prognosis was better(93.8%vs 61.5%,P<0.05).Conclusion Acute simple corpus callosum infarction has a low incidence,often accompanied by a variety of risk factors for atherosclerosis.The main manifestations of acute simple corpus callosum infarction are limb paralysis,cognitive impairment and abnormal mental behavior.The prognosis is good.
作者
陈竹林
黄光
徐斌
Chen Zhulin;Huang Guang;Xu Bin(Department of Neurology,the Fuxing Hospital,Capital Medical University,Beijing 100038,China)
出处
《脑与神经疾病杂志》
2020年第7期414-418,共5页
Journal of Brain and Nervous Diseases
关键词
胼胝体梗死
单纯
临床分析
Corpus callosum infarction
Simple
Clinical analysis
