摘要
目的:探讨超声引导下微通道与超微通道经皮肾镜碎石取石术(PCNL)对肾下盏结石患者的疗效及安全性。方法:选择2018年6月至2022年4月我院60例肾下盏结石患者,随机数表法分为对照组和试验组,每组30例。对照组患者给予微通道PCNL治疗,试验组则给予超微通道PCNL治疗。对比两组患者结石清除率、手术及住院时间,并观察两组患者治疗前后肾功能、肾血流动力学指标以及并发症发生情况。结果:两组患者性别、年龄、BMI、结石部位、结石类型、结石大小以及肾积水程度等差异无统计学意义(P>0.05)。与对照组相比,试验组手术时间短[(63.41±5.54)min vs.(76.63±6.81)min;P<0.001],住院时间短[(7.22±1.14)d vs.(8.54±1.43)d;P<0.001],结石清除率高[93.33%vs83.33%,P<0.05]。两组患者β2-MG、Scr、Hcy水平较术前降低,差异显著(P<0.05)。相比对照组,试验组β2-MG、Scr、Hcy水平更低[(4.38±1.01)mg/L vs.(5.59±1.26)mg/L;(96.35±12.43)μmol/L vs.(108.31±19.44)μmol/L;(12.64±6.08)μmol/L vs.(19.34±4.11)μmol/L;P<0.001]。两组患者并发症和临床疗效对比无显著差异(P>0.05)。结论:超微通道PCNL术可有效提高肾下盏结石患者结石清除率,对肾功能和肾血流动力学影响小,且安全性高。
Objective:To investigate the effect of ultrasound-guided percutaneous nephrolithotomy(PCNL)on renal function and safety in patients with subrenal calyx calculi.Methods:A total of 60 patients with subrenal calyx calculi who were treated in our hospital from June 2018 to April 2022 were selected as the research objects,and the patients were randomly divided into the control group(n=30)and the experimental group(n=30)according to different surgical methods,the control group was treated with traditional micro-channel PCNL,and the experimental group was treated with ultramicro-channel PCNL.The stone clearance rate,operation time and hospital stay of the two groups were compared,and the renal function indexes,renal hemodynamics,and complications before and after treatment were observed in the two groups.Results:There were no significant differences in gender,age,BMI,stone location,stone type,stone size,or renal hydronephrosis between two groups.Compared with the control group,the experimental group had shorter operation time[(63.41±5.54)min vs.(76.63±6.81)min,P<0.001],shorter hospitalization time[(7.22±1.14)d vs.(8.54±1.43)d,P<0.001],and higher stone clearance rate[(93.33%)vs.(83.33%),P<0.05].The levels ofβ2-MG,Scr and Hcy in two groups were decreased significantly compared with those before surgery(P<0.05),and the levels ofβ2-MG,Scr and Hcy in experimental group were lower than those in control group[(4.38±1.01)mg/L vs.(5.59±1.26)mg/L;(96.35±12.43)μmol/L vs.(108.31±19.44)μmol/L;(12.64±6.08)μmol/L vs.(19.34±4.11)μmol/L;P<0.001].There were no significant differences in complications and clinical efficacy between the two groups(P>0.05).Conclusion:Ultramicro-channel PCNL can effectively improve the stone clearance rate,improve the renal function index and renal hemodynamics in the clinical treatment of patients with subrenal calyx stones,and has high safety.
作者
卢国汉
吴春风
姚汝贺
李健辉
陈文杰
王亚芳
Lu Guohan;Wu Chunfeng;Yao Ruhe;Li Jianhui;Chen Wenjie;Wang Yafang(Department of Urology,Guangdong Shunde New Rongqi Hospital,Foshan 528010,China)
出处
《微创泌尿外科杂志》
2023年第2期82-86,共5页
Journal of Minimally Invasive Urology
关键词
肾镜取石术
经皮
肾盏
结石
手术后并发症
nephrolithotomy,percutaneous
kidney calices
calculi
postoperative complications
