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妊娠期高血压患者对早产儿生长发育及远期生存质量的影响 被引量:1

Effect of pregnancy induced hypertension on growth and long-term quality of life of premature infants
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摘要 目的探讨妊娠期高血压患者对早产儿生长发育及远期生存质量的影响。方法选取阿克苏市第一人民医院2017年1月~2019年1月收治的212例早产儿,根据其孕母是否合并妊娠期高血压分为对照组103例、观察组109例,对照组孕母未合并妊娠期高血压,观察组孕母合并妊娠期高血压。所有早产儿随访至矫正年龄2岁,比较两组早产儿生长发育情况(身长、体重、头围)、生存质量(生长发育迟缓发生率、喂养不耐受发生率)、凝血功能、并发症发生率。结果观察组早产儿出生时、1个月龄体重明显低于对照组(P<0.05);观察组早产儿出生时头围明显小于对照组(P<0.05);观察组早产儿喂养不耐受发生率38.68%显著高于对照组19.42%(P<0.05);观察组早产儿PT、APTT值明显高于对照组(P<0.05),FIB值明显低于对照组(P<0.05);观察组并发症发生率89.65%明显高于对照组74.76%(P<0.05)。结论孕妇合并妊娠期高血压会造成早产儿生长发育迟缓,凝血功能障碍,增加并发症发生风险,降低生存质量。 Objective To investigate the effect of gestational hypertension on growth and long-term quality of life of premature infants.Methods 212 premature infants admitted to our hospital from January 2017 to January 2019 were selected,and were divided into two groups according to the absence or presence of gestational hypertension among their mothers,the control group(n=103)and the observation group(n=109).All preterm infants were followed up to the corrected age of 2 years.The growth and development(length,weight,head circumference),quality of life(incidence of growth retardation,feeding intolerance),coagulation function and complications of the two groups were compared.Results The weight of preterm infants at birth and 1 month of age in the observation group was significantly lower than that of the control group(P<0.05).The head circumference at birth of premature infants in the observation group was significantly lower than that of the control group(P<0.05).The incidence of feeding intolerance in the observation group was significantly higher than that of the control group(38.68%vs 19.42%P<0.05).PT and APTT of preterm infants in the observation group were significantly higher than that of the control group(P<0.05),and FIB was significantly lower than that of the control group(P<0.05).The complication rate in the observation group was significantly higher than that of the control group(89.65%vs 74.76%,P<0.05).Conclusion Gestational hypertension can cause growth retardation and coagulation dysfunction in preterm infants,increase the risk of complications,and reduce quality of life.
作者 古力尼戈尔·阿不力米提 Gurinigal·Abrimiti(Department of Obstetrics,The First People’s Hospital of Aksu,Aksu,Xinjiang 843000,China)
出处 《新疆医学》 2020年第7期696-699,共4页 Xinjiang Medical Journal
关键词 妊娠期高血压 早产儿 生长发育 生存质量 Gestational Hypertension Premature Infants Growth and Development Quality of Life
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