摘要
目的观察肉芽肿性皮肤病的反射式共聚焦显微镜(Reflectance Confocal Microscopy,RCM)及皮肤镜图像特征,探讨RCM及皮肤镜在诊断此类皮肤病中的应用价值。方法回顾性分析经组织病理确诊的14例肉芽肿性皮肤病的RCM及皮肤镜图像特征;与组织病理改变进行对照分析。结果1.RCM下特征性组织样细胞脂质化或吞噬异物后,一致表现为胞质呈中高折光均质样结构;不同表现是根据体积大小、分布数量及形态的差异而不同;2.皮肤镜下均质的黄红色背景与真皮内上皮样细胞肉芽肿相对应。结论肉芽肿性皮肤病的RCM及皮肤镜图像特征与组织病理有很好的对应关系,并且RCM图像下各种组织细胞具有特异性,联合应用为疾病诊断或鉴别诊断提供重要线索,互为补充,具有较好的临床应用价值。
Objective To observe the image characteristics of granulomatous skin diseasess by reflection confocal microscopy(Reflectance Confocal Microscopy,RCM)and dermoscopy,and to discuss the application value of RCM and dermoscopy in the diagnosis of granulomatous dermatosis.Methods The RCM and dermoscopic image features of 14 cases of granulomatous dermatosis diagnosed by histopathology were analyzed retrospectively.It was compared with histopathological changes.Results 1.The characteristic tissue-like cells in RCM,after lipidization or phagocytosis of foreign bodies,showed a uniform structure of medium and high refraction.The different manifestations were different according to the difference of volume size,distribution quantity and shape.2.A homogeneous yellowred background under dermoscopy corresponded to epithelioid cell granuloma in the dermis.Conclusion The RCM and dermoscopic image features of granulomato-associated skin diseases have a good corresponding relationship with histopathology,and various histopathological cells in RCM images have more specific characteristics.The combined application provides important clues for the diagnosis or differential diagnosis of the disease and complements each other,which has good clinical application value.
作者
向芳
于世荣
陈文静
丁媛
康晓静
XIANG Fang;YU Shirong;CHEN Wenjing;DING Yuan;KANG Xiaojing(Department of Dermatology and Venereology,The People’s Hospital of Xinjiang Uygur Autonomous Region,Xinjiang Clinical Research Center for Dermatology and Venereology,Xinjiang Key Laboratory of Dermatology Research,Urumqi,830001,China)
出处
《新疆医学》
2024年第7期758-761,共4页
Xinjiang Medical Journal
基金
新疆维吾尔自治区自然科学基金(项目编号:2021D01C147)
新疆维吾尔自治区人民医院院内项目(项目编号:20220306)
关键词
反射式共聚焦显微镜
皮肤镜
肉芽肿
筛查
鉴别
reflection confocal microscope
Dermoscope
Granuloma
Screening
identify
