摘要
给予1例经多线治疗失败的弥漫大B细胞淋巴瘤患者中药联合特瑞普利单抗注射液治疗:特瑞普利单抗注射液240mg/次静脉输注,结合二陈汤合消瘰丸加减坚持服用。治疗3个月后患者身体状态从PS评分3~4分恢复到0分,经PET-CT检查全身多发肿大淋巴结缩小超过60%,疗效评价PR。第6次应用特瑞普利单抗注射液治疗时,复查甲状腺功能提示:TSH明显高于正常范围,T3、T4略低于正常范围,无特殊临床症状,诊断为继发性甲状腺功能减退,给予左甲状腺素钠片口服治疗后甲状腺功能恢复正常。该病案可为难治性非霍奇金淋巴瘤的临床治疗提供借鉴。
A case of diffuse large B cell lymphoma with multiple-line chemotherapy failure was treated with Chinese medicine combined with Toripalimab Injection:Toripalimab Injection 240 mg/times,intravenous infusion,combined with traditional Chinese medicine Erchendecoction and Xiaolei pill adhere to oral.Three months after treatment,the patient’s physical condition recovered from 3-4 points of PS score to 0 points,and the lymph nodes with multiple enlarged body were reduced by more than 60%after PET-CT examination.The curative effect was evaluated as PR.The reexamination of thyroid function in the sixth treatment with Toripalimab Injection showed that the TSH of thyroid function was significantly higher than the normal range,the T3、T4 was slightly lower than the normal range,there was no special clinical symptoms,and the diagnosis was secondary hypothyroidism.Thyroid function returned to normal after oral treatment with levothyroxine sodium tablets.It can provide a reference for the clinical treatment of refractory non-Hodgkin lymphoma.
作者
顾刚寿
崔淑娟
李成彪
Gu Gangshou;Cui Shujuan;Li Chengbiao(People's Hospital of Wuwei City,Wuwei 733000,China;Liangzhou Hospital of Wuwei City,Wuwei 733000,China)
出处
《亚太传统医药》
2021年第7期84-86,共3页
Asia-Pacific Traditional Medicine
关键词
难治性非霍奇金淋巴瘤
二陈汤
消瘰丸
PD-1抑制剂
特瑞普利单抗
中西医结合
Refractory Non-Hodgkin Lymphoma
Erchen Decoction
Xiao Luo Piu
PD-1Inhibitors
Toripalimab Injection
Integrated Traditional and Western Medicine
