目的:探究一款后生元牙膏对健康人群口腔菌群的影响。方法:纳入30名口腔健康人群,在使用牙膏前(0 d)和使用30天后(30 d)分别采集唾液,测定PLI值和CAT值,并进行16S rDNA测序,分析两组菌群结构及多样性差异。结果:与使用前相比,使用牙膏后...目的:探究一款后生元牙膏对健康人群口腔菌群的影响。方法:纳入30名口腔健康人群,在使用牙膏前(0 d)和使用30天后(30 d)分别采集唾液,测定PLI值和CAT值,并进行16S rDNA测序,分析两组菌群结构及多样性差异。结果:与使用前相比,使用牙膏后的PLI值和CAT值均显著降低(P Capnocytophaga)和孪生球菌属(Gemella)导致。结论:该款后生元牙膏能够有效减少牙菌斑,降低龋病风险,并能够调节口腔微生态。Objective: To investigate the effect of a postbiotic toothpaste on the oral microbiota of healthy people. Methods: A total of 30 oral health individuals were enrolled, and saliva was collected before (0 day) and 30 days after 30 days (30 days) of toothpaste, and PLI and CAT values were measured, and 16S rDNA sequencing was performed to analyze the differences in microbial community structure and diversity between the two groups. Results: Compared with the before use, the PLI value and CAT value were significantly reduced after using toothpaste (P < 0.0001). The dominant bacteria in the oral microbiota were basically the same before and after the use of toothpaste, but there were differences in relative abundance. Compared with the before use, the alpha diversity index Ace and Chao were significantly decreased after using toothpaste (P < 0.0001). The results of PCA analysis showed that the differences in oral microbiota composition before and after toothpaste use were mainly caused by Capnocytophaga and Gemella. Conclusion: This postbiotic toothpaste can effectively reduce dental plaque, reduce the risk of caries, and regulate the oral microecology.展开更多
锰的生物地球化学循环过程与全球尺度的营养元素循环紧密联系,是影响全球生态平衡及气候变化的重要因素之一。锰氧化菌在环境修复领域具有较大的应用潜力,已成为生物环境地球化学循环领域的研究热点之一。本文综述了锰氧化菌的分类、作...锰的生物地球化学循环过程与全球尺度的营养元素循环紧密联系,是影响全球生态平衡及气候变化的重要因素之一。锰氧化菌在环境修复领域具有较大的应用潜力,已成为生物环境地球化学循环领域的研究热点之一。本文综述了锰氧化菌的分类、作用机制、生物锰氧化物矿物特性以及在去除有机污染物方面的研究进展。详细介绍了锰氧化菌的种类,探讨了锰氧化菌的锰氧化机制以及生物锰氧化矿物特性,进一步分析了锰氧化菌在去除有机污染物方面的显著作用和相关进展。最后,对锰氧化菌在环境修复和生物技术领域的应用前景进行了展望。The biogeochemical cycling process of Mn is closely associated with the global-scale nutrient cycling and constitutes one of the crucial factors influencing global ecological balance and climate change. Mn-oxidizing bacteria possess significant potential for application in the domain of environmental remediation and have emerged as a hot research topic in recent years. This article undertakes a review of the classification, mechanism of action, characteristics of biogenic Mn oxides, and research progress in the removal of organic pollutants by Mn-oxidizing bacteria. The types of Mn-oxidizing bacteria are introduced in detail, and the Mn oxidation mechanism of manganese-oxidizing bacteria as well as the characteristics of biogenic Mn oxide minerals are deliberated. Moreover, the significant role and related progress of Mn-oxidizing bacteria in the elimination of organic pollutants are analyzed. Finally, the application prospects of Mn-oxidizing bacteria in environmental remediation and biotechnology are discussed.展开更多
文摘目的:探究一款后生元牙膏对健康人群口腔菌群的影响。方法:纳入30名口腔健康人群,在使用牙膏前(0 d)和使用30天后(30 d)分别采集唾液,测定PLI值和CAT值,并进行16S rDNA测序,分析两组菌群结构及多样性差异。结果:与使用前相比,使用牙膏后的PLI值和CAT值均显著降低(P Capnocytophaga)和孪生球菌属(Gemella)导致。结论:该款后生元牙膏能够有效减少牙菌斑,降低龋病风险,并能够调节口腔微生态。Objective: To investigate the effect of a postbiotic toothpaste on the oral microbiota of healthy people. Methods: A total of 30 oral health individuals were enrolled, and saliva was collected before (0 day) and 30 days after 30 days (30 days) of toothpaste, and PLI and CAT values were measured, and 16S rDNA sequencing was performed to analyze the differences in microbial community structure and diversity between the two groups. Results: Compared with the before use, the PLI value and CAT value were significantly reduced after using toothpaste (P < 0.0001). The dominant bacteria in the oral microbiota were basically the same before and after the use of toothpaste, but there were differences in relative abundance. Compared with the before use, the alpha diversity index Ace and Chao were significantly decreased after using toothpaste (P < 0.0001). The results of PCA analysis showed that the differences in oral microbiota composition before and after toothpaste use were mainly caused by Capnocytophaga and Gemella. Conclusion: This postbiotic toothpaste can effectively reduce dental plaque, reduce the risk of caries, and regulate the oral microecology.
文摘锰的生物地球化学循环过程与全球尺度的营养元素循环紧密联系,是影响全球生态平衡及气候变化的重要因素之一。锰氧化菌在环境修复领域具有较大的应用潜力,已成为生物环境地球化学循环领域的研究热点之一。本文综述了锰氧化菌的分类、作用机制、生物锰氧化物矿物特性以及在去除有机污染物方面的研究进展。详细介绍了锰氧化菌的种类,探讨了锰氧化菌的锰氧化机制以及生物锰氧化矿物特性,进一步分析了锰氧化菌在去除有机污染物方面的显著作用和相关进展。最后,对锰氧化菌在环境修复和生物技术领域的应用前景进行了展望。The biogeochemical cycling process of Mn is closely associated with the global-scale nutrient cycling and constitutes one of the crucial factors influencing global ecological balance and climate change. Mn-oxidizing bacteria possess significant potential for application in the domain of environmental remediation and have emerged as a hot research topic in recent years. This article undertakes a review of the classification, mechanism of action, characteristics of biogenic Mn oxides, and research progress in the removal of organic pollutants by Mn-oxidizing bacteria. The types of Mn-oxidizing bacteria are introduced in detail, and the Mn oxidation mechanism of manganese-oxidizing bacteria as well as the characteristics of biogenic Mn oxide minerals are deliberated. Moreover, the significant role and related progress of Mn-oxidizing bacteria in the elimination of organic pollutants are analyzed. Finally, the application prospects of Mn-oxidizing bacteria in environmental remediation and biotechnology are discussed.
