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Strength Developing in Clay-Andesite Brick
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作者 Víctor Julio García Alonso R. Zúñiga-Suárez +3 位作者 Carmen Omaira Márquez Juan G. Pérez Francisco Fernández-Martínez Francisco Hernández-Olivares 《Materials Sciences and Applications》 2016年第8期403-420,共18页
The objective of this work was to develop a more and better understanding of the strength developing in clay-andesite fired brick. The purpose was to improve the quality of the clay bricks that are handmade in the sou... The objective of this work was to develop a more and better understanding of the strength developing in clay-andesite fired brick. The purpose was to improve the quality of the clay bricks that are handmade in the southern region of Ecuador to make them suitable for more widespread use in the local construction industry. To achieve our goal, we first physically, chemically, and mechanically characterized the “clayey” and “sandy” materials used in the fabrication of handmade bricks in the region. Second, the optimal mixture (OM): the optimal proportion between the amounts of “clayey” and “sandy” material was sought. Third, clay bricks were prepared using the OM, baked at 950&deg;C, and characterized. In addition, bricks produced by regional artisans were characterized, and the results were compared with the results obtained for the bricks prepared using the OM. Our data reveal that the optimal mixture is 50% “clayey” material and 50% “sandy” material and that with this mixture, an average improvement in brick quality of 300% can be achieved;thus, the use of the OM makes it possible to expand the use of these bricks in the local construction industry and enables an environmentally friendly production process by reducing the intensive exploitation of regional clay deposits. This improvement is achieved by virtue of the anorthite enrichment that occurs in the solid solution, which results from the evolution of andesine. The anorthite contributes to the formation of a stronger matrix among the different grains of the material. Conditions are favorable for this enrichment process to occur when “sandy” materials with high contents of andesite, which is common in Ecuadorian soils, are used. 展开更多
关键词 ANORTHITE Andesine Andesite Component Fired Bricks Brazilian Test
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Validation of a novel imaging approach using multi-slice CT and cone-beam CT to follow-up on condylar remodeling after bimaxillary surgery 被引量:7
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作者 laura ferreira pinheiro nicolielo jeroen van dessel +5 位作者 eman shaheen carolina letelier marina codari constantinus politis ivo lambrichts reinhilde jacobs 《International Journal of Oral Science》 SCIE CAS CSCD 2017年第3期139-144,共6页
The main goal of this study was to introduce a novel three-dimensional procedure to objectively quantify both inner and outer condylar remodelling on preoperative multi-slice computed tomography (MSCT) and postopera... The main goal of this study was to introduce a novel three-dimensional procedure to objectively quantify both inner and outer condylar remodelling on preoperative multi-slice computed tomography (MSCT) and postoperative cone-beam computed tomography (CBCT) images. Second, the reliability and accuracy of this condylar volume quantification method was assessed. The mandibles of 20 patients (11 female and 9 male) who underwent bimaxillary surgery were semi-automatically extracted from MSCT/CBCT scans and rendered in 3D. The resulting condyles were spatially matched by using an anatomical landmark-based registration procedure. A standardized sphere was created around each condyle, and the condylar bone volume within this selected region of interest was automatically calculated. To investigate the reproducibility of the method, inter- and intra-observer reliability was calculated for assessments made by two experienced radiologists twice five months apart in a set of ten randomly selected patients. To test the accuracy of the bone segmentation, the inner and outer bone structures of one dry mandible, scanned according to the clinical set-up, were compared with the gold standard, micro-CT. Thirty-eight condyles showed a significant (P〈O.05) mean bone volume decrease of 26.4%_ 11.4% (502.9 mm3+ 268.1 mm3). No significant effects of side, sex or age were found. Good to excellent (ICC〉 0.6) intra- and inter-observer reliability was observed for both MSCT and CBCT. Moreover, the bone segmentation accuracy was less than one voxel (0.4 mm) for MSCT (0.3 mm __. 0.2 mm) and CBCT (0.4 mm _ 0.3 mm), thus indicating the clinical potential of this method for objective follow-up in pathological condylar resorption. 展开更多
关键词 condylar resorption Cone-beam computed tomography mandibular condyle multi-slice computed tomography three-dimensional imaging
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Rothe’s Fixed Point Theorem and the Controllability of the Benjamin-Bona-Mahony Equation with Impulses and Delay
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作者 Hugo Leiva Jose L. Sanchez 《Applied Mathematics》 2016年第15期1748-1764,共18页
For many control systems in real life, impulses and delays are intrinsic phenomena that do not modify their controllability. So we conjecture that under certain conditions the abrupt changes and delays as perturbation... For many control systems in real life, impulses and delays are intrinsic phenomena that do not modify their controllability. So we conjecture that under certain conditions the abrupt changes and delays as perturbations of a system do not destroy its controllability. There are many practical examples of impulsive control systems with delays, such as a chemical reactor system, a financial system with two state variables, the amount of money in a market and the savings rate of a central bank, and the growth of a population diffusing throughout its habitat modeled by a reaction-diffusion equation. In this paper we apply the Rothe’s Fixed Point Theorem to prove the interior approximate controllability of the following Benjamin Bona-Mohany(BBM) type equation with impulses and delay where and are constants, Ω is a domain in , ω is an open non-empty subset of Ω , denotes the characteristic function of the set ω , the distributed control , are continuous functions and the nonlinear functions are smooth enough functions satisfying some additional conditions. 展开更多
关键词 Interior Approximate Controllability Benjamin Bona-Mohany Equation with Impulses and Delay Strongly Continuous Semigroup Rothe’s Fixed Point Theorem
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Determination and Analysis of Hot Spot Areas of Deforestation Using Remote Sensing and Geographic Information System Techniques. Case Study: State Sinaloa, México
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作者 Sergio Alberto Monjardin Armenta Carlos Eduardo Pacheco Angulo +3 位作者 Wenseslao Plata Rocha Gabriela Corrales Barraza Rosendo Romero Andrade Jose Carlos Beltran Gonzalez 《Open Journal of Forestry》 2016年第4期295-304,共10页
The main objective of this research is to analyze deforestation in State Sinaloa during the period 1990-2014. For this, “deforestationhot-spot areas” were identified, by crossing maps of 1993 and 2011 at a 1:250,000... The main objective of this research is to analyze deforestation in State Sinaloa during the period 1990-2014. For this, “deforestationhot-spot areas” were identified, by crossing maps of 1993 and 2011 at a 1:250,000 scale with knowledge from environmental and forest experts from each region. Landsat images from 1990 and 2014 and Terra Amazon System were used to monitor the most critical hot spot area, applying Linear Spectral Mixture Analysis and Image Segmentation Ground Product. In order to generate the map deforestation year zero (1990), every segmented object of ground product was visually assigned to “Forest” and “No-Forest” categories. Therefore, gains and losses were interpreted for the map deforestation year one (2014). Those products were validated with the help of experts on the subject and applying a confusion matrix. Results obtained indicated that the highest forest loss was located in North-Central Sinaloa (hot spot area number two) by establishing the average annual rate of deforestation of 4741.90 ha/year with an average rate of 0.60%, being higher than the national average rate (0.37%). This result affects directlyon calculation of carbonfluxes at nationallevel. 展开更多
关键词 DEFORESTATION Hot Spot GIS LANDSAT Terra Amazon
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Success and Incoherence of Orthodox Quantum Mechanics 被引量:1
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作者 M. E. Burgos 《Journal of Modern Physics》 2016年第12期1449-1454,共6页
Orthodox quantum mechanics is a highly successful theory despite its serious conceptual flaws. It renounces realism, implies a kind of action-at-a-distance and is incompatible with determinism. Orthodox quantum mechan... Orthodox quantum mechanics is a highly successful theory despite its serious conceptual flaws. It renounces realism, implies a kind of action-at-a-distance and is incompatible with determinism. Orthodox quantum mechanics states that Schr&oumldinger’s equation (a deterministic law) governs spontaneous processes while measurement processes are ruled by probability laws. It is well established that time dependent perturbation theory must be used for solving problems involving time. In order to account for spontaneous processes, this last theory makes use of laws valid only when measurements are performed. This incoherence seems absent from the literature. 展开更多
关键词 Quantum Measurements—Time Dependent Perturbation Theory
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Situational Analysis and Expert Evaluation of the 1000 Days: Nutritional and Health Status in 4 Countries in Latin America
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作者 Andrea Ramírez Sofía Velasco +2 位作者 Oscar Bernal José Fernando Vera-Chamorro Gabriela Olagnero 《Health》 CAS 2016年第5期444-455,共12页
Background: The first 1000 days of life, including pregnancy and the first 2 years of age have been considered essential for an adequate development and growth. Several studies have stated that malnutrition during pre... Background: The first 1000 days of life, including pregnancy and the first 2 years of age have been considered essential for an adequate development and growth. Several studies have stated that malnutrition during pregnancy and not having a normal birth weight have negative impact on childhood and adulthood, and contribute to burden of disease. Adequate information on this matter provides the possibility for making recommendations on health and nutrition policies. Objective: The aim is to describe the nutritional status during the first 1000 days in four countries of Latin America: Colombia, Argentina, Chile and Brazil. Methods: The analysis consists of two complementary approaches: 1) An extensive search on published and gray literature and a critical analysis of secondary data bases was conducted in Colombia, Argentina, Chile and Brazil following a standardized methodology in 2013. Maternal and child nutritional status, breast feeding, nutri-tional deficiencies, and dietary habits during the first 1000 days were the variables of interest;2) Information gaps were identified, interviews to local experts from academia, government and hospitals were conducted to fill each of the countries information gap. Data was organized in an online data base called NutriPl@net. Results: Despite the inherent country differences, the nutritional challenges during the first 1000 days are similar. Obesity prevalence is increasing in pregnant women. Under weight remains a problem in all 4 countries, with the highest prevalence in Argentina. Over weight prevalence is highest in Chile and obesity prevalence in Brazil. Micronutrient deficiencies in pregnant women have been described, especially high for folic acid, iron, zinc, vitamins A, B6, B12, C, E and riboflavin. Moreover, in the region, anemia is the most common micronutrient deficiency during pregnancy. Gestational diabetes, hypertension, obesity and pre-eclampsia are major causes of maternal, perinatal and infant morbidity and mortality. Conclusions: In order to understand regional and country-specific needs, it is fundamental to collect standardized information related to the nutrition status during the first 1000 days. The low prevalence of exclusive breastfeeding and micronutrient deficiencies such as iron, zinc and vitamin A as risk factors for morbidity and mortality in children 0 - 2 years old is common and priority issues in the region. Persistence of anemia despite the use of fortified foods and supplementation remains a problem, and no complete data regarding sugar, sodium and fatty acids consumption and changes in the diet and habits before, during and after pregnancy are available. The gaps that are found to justify the need for further studies including population based surveys with standardized methodology that can warrant comparability. 展开更多
关键词 BREASTFEEDING INFANTS Nutrition Pregnancy Latin America
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Morbidity Due to Obesity, Hypertension and Diabetes II Attributable to Non-Breastfeeding and Low Birth Weight during the 1000 Days of Life: Estimation of the Population Attributable Fraction
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作者 Andrea Ramírez Oscar Bernal +1 位作者 Jesús Rodríguez José David Pinzón 《Health》 CAS 2016年第5期386-401,共16页
Introduction: There is evidence that malnutrition during the first 1000 days of life contributes to the development of chronic diseases in adulthood and therefore may produce a lasting impact on the health of the popu... Introduction: There is evidence that malnutrition during the first 1000 days of life contributes to the development of chronic diseases in adulthood and therefore may produce a lasting impact on the health of the population. Colombia, like other middle-income countries suffers the double burden of malnutrition in pregnant women and children under 5 years. Also, chronic diseases have positioned within the leading causes of morbidity and mortality. Objective: The aim is to estimate the burden of disease of noncommunicable chronic diseases-NCD’s (hypertension, obesity, diabetes mellitus II) in adults attributable to nutritional risk factors (no-breastfeeding and low birthweight) in the period of 1000 days in Colombia. Methods: The population attributable fraction and the number of NCD’s (hypertension, diabetes mellitus II and obesity) cases due to the risk factors (low birthweight and no-breastfeeding) were estimated. Prevalences of NCD’s and risk factors of interest were taken from national health surveys. Effect measures (odds ratios/relative risks) of the associations 1—low birthweight and hypertension, diabetes mellitus II and 2—no-breastfeeding and obesity were obtained after a systematic literature search. Results: It was estimated that not receiving breastfeeding in the 1000 days could contribute up to 29.9% of all cases of obesity, equivalent to about 4,009,779 cases across the country. Low birth weight could contribute up to 2.1% of cases of hypertension in men and to 4.0% of cases in women, equivalent to 103.769 cases across the country. In addition, low birth weight could contribute to 6.3% of diabetes mellitus II cases, which is equivalent to 23.857 cases in the country. Conclusion: In Colombia, risk factors during the first 1000 days like not receiving breastfeeding and having low birth weight could contribute up to 4,113,549 cases of obesity, hypertension and diabetes mellitus II, with important implications for the health of the population and the Colombian health system. 展开更多
关键词 Epidemiologic Measurements BREASTFEEDING Low Birth Weight Chronic Disease Public Health
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Auditory Gain, Quality of Life, and Audiological Benefits in Bone-Anchored Hearing Device Users in Fundación SantaféDe Bogotá, Colombia
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作者 Augusto Peñaranda Juan Manuel Garcia +4 位作者 Maria Leonor Aparicio Felipe Montes Clemencia Barón Roberto C. Jiménez Daniel Peñaranda 《International Journal of Otolaryngology and Head & Neck Surgery》 2016年第2期44-53,共10页
The objective of this study is to determine the auditory gain, quality of life, audiological benefits, in bone-anchored hearing device users (BAHA). It is a retrospective and concurrent evaluation of thirty patients f... The objective of this study is to determine the auditory gain, quality of life, audiological benefits, in bone-anchored hearing device users (BAHA). It is a retrospective and concurrent evaluation of thirty patients fitted unilaterally and seven fitted bilaterally for at least six months. Patients were assessed with audiometric testing and application of Glasgow Benefit Inventory (GBI) and Abbreviated Profile of Hearing Aid Benefit (APHAB). Regarding sound-field pure audiometry results, we found a statistically significant gain in all frequencies using the bone-anchored device. APHAB scores showed statistically significant subjective audiological gains in all subscales except for the aversiveness subscale. GBI mean scores for all items in both groups were all above 3, suggesting quality of life improvement in conductive and mixed hearing loss patients. BP100 users showed a greater clinical gain in the APHAB global score and subscales compared with Divino users. In conclusion the BAHA provides significant auditory gain, subjective audiological benefits and improves quality of life in all BAHA users. This study shows a significant clinical and statistical benefit of BAHA measured by audiometric testing and by the APHAB and GBI questionnaires. 展开更多
关键词 BAHA Quality of Life Audiological Benefits Auditory Gain
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The Nature, Origin and Propagation of the Electric Field: A New Insight to Fundamental Physics
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作者 Narahari V. Joshi 《Journal of Modern Physics》 2016年第10期1132-1137,共6页
The nature, origin and propagation of the electric field are discussed for the first time on the basis of the presence of vibrating strings in the space and their self-excitation process. It is considered that the ele... The nature, origin and propagation of the electric field are discussed for the first time on the basis of the presence of vibrating strings in the space and their self-excitation process. It is considered that the electron is formed from strings and it has specific vibrational frequency. This excites the strings which are close by with the self-excitation process. This procedure which is continuous in the space according to the symmetry and vibrational energy in the form of waves spreads near the electron (or the charge particle), which behaves and carries energy known as electric field. In fact, the electron does not continuously emit energy in any form but induces (or excites) and organizes energy in a self-sustain vibrational form and extends in three dimensional space. Only on the basis of the presence of strings (vibrational energy), several electromagnetic phenomena have been explained in a consistent way. The vibrational nature of the electric field is also examined with the help of Stark effect and X-ray diffraction approach to support the present view. 展开更多
关键词 Electric Field Strings as Compact Liquid Self Excitation
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老年期抑郁障碍规范治疗的德尔菲法专家共识调查研究 被引量:1
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作者 李志营 国灿灿 +4 位作者 周佳男 刘肇瑞 陈静宁 于欣 孙新宇 《中国医学前沿杂志(电子版)》 北大核心 2025年第3期96-101,共6页
目的 本研究运用德尔菲法构建老年期抑郁障碍(late-life depression,LLD)规范治疗的专家共识,旨在整合专家意见,为老年期抑郁障碍临床治疗提供参考依据,以提升治疗的规范性与有效性。方法 于2024年7—11月遴选全国15个省(自治区、直辖市... 目的 本研究运用德尔菲法构建老年期抑郁障碍(late-life depression,LLD)规范治疗的专家共识,旨在整合专家意见,为老年期抑郁障碍临床治疗提供参考依据,以提升治疗的规范性与有效性。方法 于2024年7—11月遴选全国15个省(自治区、直辖市)31名老年临床精神科专家,进行两轮问卷调查。问卷涵盖老年期抑郁障碍治疗的多方面内容,如治疗原则、药物选择、心理治疗等。运用描述性统计分析方法剖析专家基本信息、意见集中程度,对问卷各项目实施频数分析,从而提炼出规范化治疗的指导意见。结果 两轮共有31名老年临床精神科专家参与,涉及15个省(自治区、直辖市),均为副高及以上职称,平均年龄52岁,平均从业27.9年,其中精神专科医院20名,综合医院精神科10名,其他1名,两轮调查积极系数达96.77%。在老年期抑郁障碍规范治疗方面达成专家共识,如老年期抑郁障碍治疗应安全(100.00%)、有效(83.33%);心理治疗推荐支持治疗(93.33%)、问题解决治疗(83.33%);药物治疗原则应小剂量起始(93.33%)、尽量单一用药(90.00%);如果首选的抗抑郁药物无效,下一步的药物方案调整为现有药物加量(83.33%)或更换不同类型抗抑郁药物(83.33%)。针对不同类型老年期抑郁障碍的药物推荐达成共识,如首发抑郁障碍中推荐舍曲林(100.00%)等。然而,在合并用药时机、特殊治疗方法应用细节等方面仍存在争议。结论 本研究在老年期抑郁障碍的治疗原则,药物选择,合并用药方案及心理治疗的应用等多个存在分歧的领域达成了共识,为进一步深入研究和临床决策提供了有价值的参考和指导。 展开更多
关键词 老年期抑郁障碍 规范治疗 德尔菲法 专家共识
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一种用于精神分裂症的新型阿立哌唑微球长效制剂的药动学、疗效和安全性研究 被引量:1
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作者 李安宁 崔一民 +14 位作者 靳胜春 尚德为 郭剑雄 蔺华利 张明 魏波 万凤 谭云龙 王丽莉 周建初 刘萍 范莲莲 孙菊水 陈斌 王刚 《中国新药杂志》 北大核心 2025年第15期1637-1646,共10页
目的:与传统的微晶剂型相比,基于微球技术的阿立哌唑长效注射剂(long-acting injectable formulation,LAI)旨在提高生物利用度并减少总剂量。本研究旨在评估2种剂型的药动学特征和生物等效性,并评估阿立哌唑微球长效制剂对稳定期精神分... 目的:与传统的微晶剂型相比,基于微球技术的阿立哌唑长效注射剂(long-acting injectable formulation,LAI)旨在提高生物利用度并减少总剂量。本研究旨在评估2种剂型的药动学特征和生物等效性,并评估阿立哌唑微球长效制剂对稳定期精神分裂症患者的疗效和安全性。方法:本研究为一项多中心随机开放标签临床试验,共纳入260例稳定期精神分裂症患者。受试者按2∶2∶1的比例随机分配,分别每4周注射1次微球制剂350 mg(MS 350 mg)或对照制剂400 mg(AM 400 mg)共5次注射;或每6周注射1次500 mg微球制剂(MS 500 mg)共4次注射。主要目的是评估稳态生物等效性(AUC_(0-d28))和血浆浓度的波动程度。采用阳性和阴性症状量表(positive and negative symptom scale,PANSS)评分评估疗效,安全性结果评估包括治疗出现的不良事件(treatment-emergent adverse events,TEAEs)和药物不良反应(adverse drug reactions,ADRs)。结果:MS 350 mg制剂与AM 400 mg制剂具有生物等效性。两组在第1次注射后第12周、第20周和第24周的PANSS评分均较基线显著降低,组间无显著差异。MS 350 mg组血药浓度波动程度较低,表明其药物暴露谱更为稳定。MS 350 mg组的TEAEs(75.7%vs 54.4%)及ADRs(83.5%vs 62.1%)发生率均低于AM 400 mg组。结论:微球制剂与微晶制剂具有生物等效性,可持续改善患者症状,血浆波动更小且安全性更优。这些研究结果支持微球制剂作为精神分裂症长期治疗的可行方案。 展开更多
关键词 阿立哌唑微球 长效注射剂 药动学 疗效 安全性 波动度
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黄芪多糖对舍饲滩羊生产性能、胴体性能及肉品质的影响 被引量:7
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作者 陈国顺 田斌 +5 位作者 高燕程 李延翠 田文锦 杨文静 吴万成 黄立军 《中国农业科技导报(中英文)》 北大核心 2025年第2期150-157,共8页
为阐明黄芪多糖对滩羊生长性能、屠宰性能和肉品质的影响,选择24只健康、体重相近(22.17±1.21 kg)的50日龄滩羊公羔,随机分为4组进行育肥试验,试验日粮分别设置为基础日粮组(对照组)、基础日粮+0.05%黄芪多糖组(试验Ⅰ组)、基础日... 为阐明黄芪多糖对滩羊生长性能、屠宰性能和肉品质的影响,选择24只健康、体重相近(22.17±1.21 kg)的50日龄滩羊公羔,随机分为4组进行育肥试验,试验日粮分别设置为基础日粮组(对照组)、基础日粮+0.05%黄芪多糖组(试验Ⅰ组)、基础日粮+0.10%黄芪多糖组(试验Ⅱ组)和基础日粮+0.15%黄芪多糖组(试验Ⅲ组)。在试验的第0、10和70天分别称重,在试验期结束时(第70天)屠宰并测定胴体性性能和肉品质。结果显示,与对照组相比,试验Ⅱ组滩羊的末重和平均日增重显著增加,饲料转化率显著降低;试验Ⅱ组的胴体重和屠宰率显著增加;试验Ⅱ组和试验Ⅲ组的熟肉率显著增加;试验Ⅰ组和试验Ⅱ组的背膘厚显著降低,试验Ⅱ组处理的亮度(L^(*))显著降低;试验Ⅱ组和试验Ⅲ组滩羊肌肉的甘氨酸、天冬氨酸和总氨基酸含量显著增加,鲜味氨基酸含量在添加了黄芪多糖处理中显著增加;试验Ⅱ组的单不饱和脂肪酸(monounsaturated fatty acids,MUFA)和多不饱和脂肪酸含量显著增加;试验Ⅱ组和试验Ⅲ组的MUFA/TFA(总脂肪酸,total fatty acids)显著增加。综上所述,日粮中添加0.10%黄芪多糖可以提高滩羊的生长性能,改善胴体性能及肉品质。 展开更多
关键词 黄芪多糖 滩羊 生产性能 羊肉 脂肪酸
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数字农业技术在马铃薯产业中的实践探索 被引量:1
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作者 陈小花 赵维涛 +2 位作者 李继明 姚乔花 赵永萍 《寒旱农业科学》 2025年第3期215-219,共5页
为加快定西市安定区马铃薯产业现代化步伐,介绍了安定区马铃薯产业发展状况,阐述了安定区通过数字农业试点建设将数字农业技术应用于马铃薯产业中所取得的成果。通过分析数字农业技术在定西市安定区经济发展中的良好作用及存在问题,建... 为加快定西市安定区马铃薯产业现代化步伐,介绍了安定区马铃薯产业发展状况,阐述了安定区通过数字农业试点建设将数字农业技术应用于马铃薯产业中所取得的成果。通过分析数字农业技术在定西市安定区经济发展中的良好作用及存在问题,建议强化组织领导、夯实平台数据信息、提高平台使用的覆盖面、完善平台功能、增加试点范围,为同类地区数字农业发展提供参考。 展开更多
关键词 数字农业 马铃薯产业 定西市安定区
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日粮中不同水平蚕豆对育肥猪生长性能、血清生化指标及屠宰性能的影响 被引量:1
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作者 刘彩琴 李丽 +1 位作者 卢国龙 张世军 《中国饲料》 北大核心 2025年第8期137-140,共4页
文章旨在分析日粮中不同水平蚕豆对育肥猪生长性能、血清生化指标及屠宰性能的影响。试验将96头体重相近[(86.56±2.47)kg]的育肥猪随机分为4组,对照组根据GB/T 5915-2020配制常规饲料,其余3组配置含5%、10%、15%蚕豆的等氮饲料,每... 文章旨在分析日粮中不同水平蚕豆对育肥猪生长性能、血清生化指标及屠宰性能的影响。试验将96头体重相近[(86.56±2.47)kg]的育肥猪随机分为4组,对照组根据GB/T 5915-2020配制常规饲料,其余3组配置含5%、10%、15%蚕豆的等氮饲料,每组3个重复,每个重复8头。预饲期7d,正试期35d。结果:与对照组相比,(1)蚕豆添加水平为5%时,生长性能各项指标无显著差异(P>0.05);蚕豆添加水平为15%时,平均日增重显著下降10.74%(P<0.05),料重比显著提高12.53%(P<0.05)。(2)蚕豆添加水平为10%~15%时,血清总蛋白、胆固醇含量显著下降(P<0.05)。(3)蚕豆添加水平为10%~15%时,胴体重、屠宰率、眼肌面积显著下降(P<0.05)。结论:育肥猪日粮中添加5%水平蚕豆,对各项指标均无显著影响(P>0.05)。而添加10%~15%水平蚕豆,降低了育肥猪的生长性能、血清总蛋白、胆固醇含量及屠宰性能。因此,育肥猪日粮中蚕豆的适宜添加水平为5%。 展开更多
关键词 蚕豆 育肥猪 生长性能 血清生化指标 屠宰性能
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1例肾移植术后互隔链格孢菌致肺部感染患者抗感染治疗的药学监护 被引量:1
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作者 张瑞霞 王岩萍 高珊 《中国药房》 北大核心 2025年第4期491-495,共5页
目的为肾移植术后互隔链格孢菌致肺部感染患者治疗方案的选择及药学监护提供参考。方法临床药师参与1例肾移植术后互隔链格孢菌致肺部感染患者的抗感染治疗过程,根据患者的临床表现及实验室检查结果并结合文献,临床药师认为患者可能为... 目的为肾移植术后互隔链格孢菌致肺部感染患者治疗方案的选择及药学监护提供参考。方法临床药师参与1例肾移植术后互隔链格孢菌致肺部感染患者的抗感染治疗过程,根据患者的临床表现及实验室检查结果并结合文献,临床药师认为患者可能为互隔链格孢菌导致的呼吸道过敏后继发肺部感染,不能排除军团菌和腺病毒感染。临床药师建议口服伏立康唑片抗真菌,莫西沙星片抗军团菌,减少他克莫司剂量,停用更昔洛韦;同时还密切监护患者伏立康唑用药期间的血药谷浓度及可能出现的不良反应。结果医生采纳临床药师建议,患者病情平稳后准予出院。结论互隔链格孢菌是免疫抑制患者尤其是同时伴有呼吸道过敏反应时的潜在致病菌,伏立康唑可作为其抗感染治疗的首选方案。临床药师通过调整伏立康唑剂量,延长疗程,监测患者肝功能及视觉功能,关注伏立康唑与免疫抑制剂的相互作用等药学服务手段,保障了患者的用药安全。 展开更多
关键词 互隔链格孢菌 真菌感染 肾移植 药学监护
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清热解郁方治疗双相抑郁火热内郁证的随机双盲对照研究
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作者 尹冬青 贾竑晓 +2 位作者 李雪 郑思思 宁艳哲 《首都医科大学学报》 北大核心 2025年第3期479-486,共8页
目的明确清热解郁方治疗双相抑郁的有效性和安全性。方法本研究采用随机、双盲、中药、西药安慰剂对照设计方法。对符合入组标准的双相抑郁火热内郁证的患者80例,按照1∶1比例,将患者分为试验组(西药模拟片+中药配方颗粒)和对照组(西药... 目的明确清热解郁方治疗双相抑郁的有效性和安全性。方法本研究采用随机、双盲、中药、西药安慰剂对照设计方法。对符合入组标准的双相抑郁火热内郁证的患者80例,按照1∶1比例,将患者分为试验组(西药模拟片+中药配方颗粒)和对照组(西药+中药安慰剂),入组后脱落7例,试验组36例,对照组37。分别于基线期和治疗后第2周、第4周、第8周进行中医火热内郁证积分(Traditional Chinese Medicine Heat Internal Depression Syndrome,TCMIDS)、汉密尔顿抑郁量表-24项(Hamilton Depression Scale-24 Item,HAMD-24)、汉密尔顿焦虑量表(Hamilton Anxiety Scale,HAMA)、33项轻躁狂清单(Hypomania Checklist-33,HCL-33)、Young氏躁狂量表(Young Manic Rating Scale,YMRS)和治疗不良反应量表(Treatment Emergent Symptom Scale,TESS)评分,记录重要体征、不良事件;分别于筛选期和治疗后的第8周进行血常规、肝功能、肾功能、尿常规和心电图检查;中途退出患者的检查项目同第8周。主要治疗效果评价指标为第8周HAMD评分较基线的变化。次要治疗效果评价指标:第8周TCMIDS、HAMA、HCL-33、YMRS评分较基线的变化。结果试验组和对照组不同时点HAMD-24项量表评分较基线均有明显降低,差异有统计学意义(P<0.01),但与对照组相比,试验组在第4周和第8周时HAMD-24项量表评分下降幅度更为明显,差异有统计学意义(P<0.01)。两组TCMIDS评分和HAMD评分不同时点较基线均有明显下降,差异有统计学意义(P<0.01),与对照组相比,试验组在TCMIDS评分、HAMD评分在第4周和第8周量表评分下降幅度更为明显,差异统计学意义(P<0.01)。两组YMRS和HCL-33评分不同时点较基线均有明显下降,差异有统计学意义(P<0.01),但两组之间对比,差异无统计学意义。结论清热解郁方能有效缓解双相抑郁的抑郁和焦虑情绪,且较西药有更多优势,另外对双相情感障碍轻躁狂或躁狂相关症状有一定疗效,且该疗法无转燥风险,安全性较好,不良反应较少。 展开更多
关键词 双相抑郁 双相情感障碍 清热解郁方 随机对照试验 中医
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不同干燥方式对铁皮石斛花营养成分的影响
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作者 刘景玲 李佩钰 +4 位作者 赵萌 左小容 胡秀芳 董娟娥 马亚团 《保鲜与加工》 北大核心 2025年第10期95-104,共10页
为研究不同干燥方式和堆叠厚度对人工栽培铁皮石斛花营养品质的影响,采用8种常用干燥方法对单层和双层堆叠铁皮石斛花进行干燥加工处理。基于主成分分析法,分析检测铁皮石斛花中氨基酸种类和含量、甘露糖含量、粗蛋白含量等指标以探究... 为研究不同干燥方式和堆叠厚度对人工栽培铁皮石斛花营养品质的影响,采用8种常用干燥方法对单层和双层堆叠铁皮石斛花进行干燥加工处理。基于主成分分析法,分析检测铁皮石斛花中氨基酸种类和含量、甘露糖含量、粗蛋白含量等指标以探究其营养品质变化,筛选适宜的铁皮石斛花干燥方法。结果表明:铁皮石斛花中含有17种氨基酸,包括7种必需氨基酸,氨基酸组成和含量与标准蛋白的比例接近,是一种极具开发潜力的植物源蛋白。主成分分析结果显示,单层阴干样品的铁皮石斛花营养品质得分最高;而在热风干燥条件下,40℃单层烘干样品得分最高。综上,铁皮石斛花最适干燥方法是阴干单层,40℃单层干燥是大批量烘干铁皮石斛花的最适方法;相比于单层花,双层花堆叠干燥条件下铁皮石斛花中营养品质相关指标降低,总黄酮含量显著降低。在综合考察不同干燥方式和堆叠厚度对铁皮石斛花营养成分影响的基础上,提出了少量和大批量干燥铁皮石斛花的最佳条件,为其加工开发提供理论依据。 展开更多
关键词 铁皮石斛花 干燥方式 堆叠厚度 营养成分 氨基酸
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老年精神障碍患者“互联网+护理服务”需求问卷的信效度研究
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作者 李金源 张猛 +2 位作者 李智 李玉超 周磊 《护理与康复》 2025年第10期1-8,共8页
目的编制科学、全面的老年精神障碍患者“互联网+护理服务”需求问卷,并检验其信效度。方法以华生关怀理论和马斯洛需求层次理论为指导,采用文献回顾、半结构式访谈法形成问卷的条目池,经专家函询、预调查及项目分析筛选问卷条目,获得... 目的编制科学、全面的老年精神障碍患者“互联网+护理服务”需求问卷,并检验其信效度。方法以华生关怀理论和马斯洛需求层次理论为指导,采用文献回顾、半结构式访谈法形成问卷的条目池,经专家函询、预调查及项目分析筛选问卷条目,获得正式问卷。采用便利抽样法,选取2023年1月~6月天津市安定医院405例康复期老年精神障碍患者进行问卷调查,并进行问卷信效度检验。结果最终形成的问卷包括监测与治疗需求、疾病管理需求、精神与心理需求、健康教育与康复指导需求、社会支持需求5个维度,共33个条目。问卷的Cronbach'sα系数为0.978,Guttman分半信度系数为0.938。内容效度指数为0.935,探索性因子分析共提取5个公因子,累积方差贡献率为84.470%,验证性因子分析结果提示,模型适配理想,因子结构稳定。结论老年精神障碍患者“互联网+护理服务”需求问卷信效度良好,可用于评估老年精神障碍患者的“互联网+护理服务”需求。 展开更多
关键词 老年人 精神障碍 互联网+护理服务 需求
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乳糜血对磷酸酶法检测血清锂浓度的干扰及应对处理措施
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作者 凌四海 何山 +3 位作者 韦美萍 贺静 齐小梅 刘辰庚 《现代检验医学杂志》 2025年第4期199-203,共5页
目的探讨不同程度乳糜血对磷酸酶法检测血清锂(Li)浓度的干扰影响及应对处理措施。方法收集不含锂的重度乳糜血清混合样本,制备乳糜血浓缩液。收集服用碳酸锂、血脂正常的患者混合血清样本用于甘油三酯(TG)干扰实验;同时收集未服用碳酸... 目的探讨不同程度乳糜血对磷酸酶法检测血清锂(Li)浓度的干扰影响及应对处理措施。方法收集不含锂的重度乳糜血清混合样本,制备乳糜血浓缩液。收集服用碳酸锂、血脂正常的患者混合血清样本用于甘油三酯(TG)干扰实验;同时收集未服用碳酸锂的患者血清样本28例,依据TG干扰实验结果,选择对血清锂浓度检测无干扰的最大TG浓度作为稀释的目标浓度,进而计算目标稀释倍数。向每个样本中添加锂溶液,计算真实理论值。样本均分为3组,分别采用直接检测法、生理盐水稀释法及高速离心法(13000r/min,10min)处理,测定血清锂浓度,比较不同处理方法的结果差异。结果TG浓度>4.77mmol/L的乳糜血对磷酸酶法检测血清锂产生干扰。生理盐水稀释法测定值偏差最大(t=10.87,P<0.0001),而高速离心法测定值与真实理论值最接近(t=2.97,P=0.0369),准确度较高。直接检测法虽与高速离心法结果高度相关(r=0.9765,P<0.0001),但仍存在显著均值差异(t=5.37,P<0.0001)。结论TG浓度>4.77mmol/L的乳糜血清样本应避免使用生理盐水稀释法。高速离心法可以有效去除干扰,使测定结果更接近真实理论值,推荐作为优化方法。 展开更多
关键词 乳糜血清 血清锂 磷酸酶法 高速离心 生理盐水稀释
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围产期抑郁发展轨迹的异质性及其相关因素
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作者 王晨 李安宁 +1 位作者 侯金芹 姜海利 《中国心理卫生杂志》 北大核心 2025年第8期720-726,共7页
目的:探索围产期抑郁的发展轨迹异质性及相关因素。方法:于2020年1月-2021年6月在北京妇产医院,对孕中期至产后3个月的孕产妇进行5次抑郁评估,使用爱丁堡产后抑郁量表筛查抑郁症状。同时在入组时收集社会人口学信息、婚姻满意度、社会... 目的:探索围产期抑郁的发展轨迹异质性及相关因素。方法:于2020年1月-2021年6月在北京妇产医院,对孕中期至产后3个月的孕产妇进行5次抑郁评估,使用爱丁堡产后抑郁量表筛查抑郁症状。同时在入组时收集社会人口学信息、婚姻满意度、社会支持度信息。使用潜类别增长模型分析抑郁发展轨迹异质性,并运用logistic回归分析其影响因素。结果:1416例孕妇完成至少3次测评,识别出2个轨迹亚组:其中1023例(72.2%)总体分数较低,抑郁轨迹以抛物线形式进行性上升,称为曲线组;另有393例(27.8%)抑郁轨迹趋于不变,总体得分高,称为直线组。较大年龄、较高婚姻满意度和社会支持度者进入直线组的风险降低(OR=0.96、0.94、0.89);自身及家族抑郁病史者进入直线组风险升高(OR=2.50、6.51)。结论:围产期抑郁症状变化趋势存在个体差异,较大年龄、较高的婚姻满意度和社会支持度降低持续性较高抑郁水平的风险,个人及家族抑郁病史可能增加其风险。 展开更多
关键词 围产期抑郁 轨迹 潜类别增长曲线模型 风险因素
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