探索中国女性高危型人乳头瘤病毒(High-risk human papillomavirus,HR-HPV)感染的自然转归状况,以指导开展正确的健康教育以及HPV感染相关的治疗药物或疫苗的研发。从PubMed,Embase,CNKI,万方等数据库中检索和筛选自建库以来至2024年5...探索中国女性高危型人乳头瘤病毒(High-risk human papillomavirus,HR-HPV)感染的自然转归状况,以指导开展正确的健康教育以及HPV感染相关的治疗药物或疫苗的研发。从PubMed,Embase,CNKI,万方等数据库中检索和筛选自建库以来至2024年5月有关中国女性HR-HPV感染自然消退以及持续感染相关的文章。使用纽卡斯尔-渥太华量(NOS)评估所纳入文献的质量,采用随机效应模型计算HR-HPV感染的自然转阴率(95%CI)以及HR-HPV感染的持续阳性率(95%CI),并分析随访时间与HR-HPV自然转阴率、HR-HPV持续阳性率之间的关联。最后通过漏斗图、Egger′s检验评价发表偏倚,采用敏感性分析评估合并参数值的稳健程度。共纳入54篇文章,涉及HR-HPV持续感染的文章共52篇,HR-HPV感染自然转阴的文章共51篇,NOS量表评分均≥5分共53篇。随访时间为6个月、12个月、24个月、36个月时,中国女性HR-HPV感染自然转阴率分别为0.3033(0.2238,0.3892),0.5174(0.4559,0.5786),0.6538(0.5834,0.7210),0.7608(0.6642,0.8455)。HR-HPV持续阳性率分别为0.6780(0.5897,0.7603),0.4528(0.3930,0.5133),0.2963(0.2319,0.3649),0.2294(0.1378,0.3362)。随着随访时间的延长,在中国高危人乳头瘤病毒(HR-HPV)的自然清除率逐渐增加,持续感染率逐渐下降。到了36个月时,约有22.94%的女性仍呈HR-HPV持续阳性。这一数据对于正确进行健康教育以及指导后续HPV感染相关的治疗药物或疫苗研发具有重要意义。展开更多
The Mae Moh lignite-fired power plant is the only lignite-fired power plant and is the main point source of CO_(2)emissions in Thailand.This power plant uses lignite supplied from the Mae Moh lignite open-pit mine in ...The Mae Moh lignite-fired power plant is the only lignite-fired power plant and is the main point source of CO_(2)emissions in Thailand.This power plant uses lignite supplied from the Mae Moh lignite open-pit mine in the same vicinity.Carbon dioxide sequestration technologies can play a crucial role in reducing carbon emissions in the energy sector,particularly in coal-fired power plants.This case study provides the first assessment of the potential for geological CO_(2)storage in coal seams at the Mae Moh coal mine in northern Thailand based on literature reviews.The Mae Moh Basin is a rift basin with a complex normal fault and contains coal seams at different depths separated by claystones.The geological setting potentially offers favorable conditions for the geological storage of CO_(2)in the coal seams through a combination of physical and chemical trapping mechanisms.The findings suggest that the Mae Moh coal mine is suitable for geological CO_(2)storage,especially in K and Q coal seams.However,leakage risks,storage capacity,and CO_(2)-water-coal reactions could be problematic.Thus,more subsurface studies should be carried out,and more detailed criteria should be considered before CO_(2)sequestration is undertaken in the Mae Moh coal mine.展开更多
Bedding-parallel fibrous calcite veins(BPCVs)are found extensively in sedimentary basins and usually developed in petroleum source rock;however,their origin remains debated.This study investigates the formation of BPC...Bedding-parallel fibrous calcite veins(BPCVs)are found extensively in sedimentary basins and usually developed in petroleum source rock;however,their origin remains debated.This study investigates the formation of BPCVs in the Permian carbonate rocks of the Khao Khwang Formation,central Thailand,through petrographic,geochemical,and isotopic analyses,along with total organic carbon(TOC)content assessment.Five samples,including 9 veins and 5 host rocks,were analyzed.The petrographic obser-vations show that the BPCVs exhibit cone-in-cone structure and beef vein and are classified as unitaxial veins.The geochemical analyses and stable isotope compositions suggest local fluid sources originated from inorganic carbonates and diagenetic formation fluids within the microbial methanogenic zone.The BPCVs have an averageδ13 CVPDB value of 3.04‰±0.30‰and an averageδ18 OVPDB value of 10.75‰±0.62‰,while the host rocks have an averageδ13 CVPDB value of 1.88‰±1.10‰and an averageδ18 OVPDB value of 10.77‰±0.39‰.The mineral compositions and element contents of the host rock and fibrous calcite veins are similar,with a strong negative relationship between calcium and other ele-ments.The rare earth element(REE)distribution patterns from the calcite veins are similar to the host rocks,with positive Ce anomalies and small positive Eu anomalies.Oxygen isotope data suggest vein formation at temperatures between 62℃and 75℃,corresponding to the onset of the oil window.The in-situ U-Pb dating indicates that fibrous calcite veins formed between the Early to Middle Permian period[(260.1±4.5)to(288.9±4.8)Ma)].Microstructural and geochemical evidence suggests that vein initiation resulted from fluid overpressure of a supersaturation of pore fluids within semi-consolidated sediments,with continuous vein dilatation driven by crystallization forces.This study illustrates that the BPCVs of the Khao Khwang Formation highlight significant potential in accurately assessing the evolution of hydrocarbon generation.展开更多
文摘探索中国女性高危型人乳头瘤病毒(High-risk human papillomavirus,HR-HPV)感染的自然转归状况,以指导开展正确的健康教育以及HPV感染相关的治疗药物或疫苗的研发。从PubMed,Embase,CNKI,万方等数据库中检索和筛选自建库以来至2024年5月有关中国女性HR-HPV感染自然消退以及持续感染相关的文章。使用纽卡斯尔-渥太华量(NOS)评估所纳入文献的质量,采用随机效应模型计算HR-HPV感染的自然转阴率(95%CI)以及HR-HPV感染的持续阳性率(95%CI),并分析随访时间与HR-HPV自然转阴率、HR-HPV持续阳性率之间的关联。最后通过漏斗图、Egger′s检验评价发表偏倚,采用敏感性分析评估合并参数值的稳健程度。共纳入54篇文章,涉及HR-HPV持续感染的文章共52篇,HR-HPV感染自然转阴的文章共51篇,NOS量表评分均≥5分共53篇。随访时间为6个月、12个月、24个月、36个月时,中国女性HR-HPV感染自然转阴率分别为0.3033(0.2238,0.3892),0.5174(0.4559,0.5786),0.6538(0.5834,0.7210),0.7608(0.6642,0.8455)。HR-HPV持续阳性率分别为0.6780(0.5897,0.7603),0.4528(0.3930,0.5133),0.2963(0.2319,0.3649),0.2294(0.1378,0.3362)。随着随访时间的延长,在中国高危人乳头瘤病毒(HR-HPV)的自然清除率逐渐增加,持续感染率逐渐下降。到了36个月时,约有22.94%的女性仍呈HR-HPV持续阳性。这一数据对于正确进行健康教育以及指导后续HPV感染相关的治疗药物或疫苗研发具有重要意义。
基金financial support from the creation of a teaching-led research platform,the Ratchadaphisek Somphot Endowment Fund,Chulalongkorn University。
文摘The Mae Moh lignite-fired power plant is the only lignite-fired power plant and is the main point source of CO_(2)emissions in Thailand.This power plant uses lignite supplied from the Mae Moh lignite open-pit mine in the same vicinity.Carbon dioxide sequestration technologies can play a crucial role in reducing carbon emissions in the energy sector,particularly in coal-fired power plants.This case study provides the first assessment of the potential for geological CO_(2)storage in coal seams at the Mae Moh coal mine in northern Thailand based on literature reviews.The Mae Moh Basin is a rift basin with a complex normal fault and contains coal seams at different depths separated by claystones.The geological setting potentially offers favorable conditions for the geological storage of CO_(2)in the coal seams through a combination of physical and chemical trapping mechanisms.The findings suggest that the Mae Moh coal mine is suitable for geological CO_(2)storage,especially in K and Q coal seams.However,leakage risks,storage capacity,and CO_(2)-water-coal reactions could be problematic.Thus,more subsurface studies should be carried out,and more detailed criteria should be considered before CO_(2)sequestration is undertaken in the Mae Moh coal mine.
基金supported by the Ratchadaphisek Somphot Endowment Fund(the 90th Anniversary of Chulalongkorn University Fund,GCUGR1125662052Mthe Exchange Faculty Travel Grant,CTG168038)。
文摘Bedding-parallel fibrous calcite veins(BPCVs)are found extensively in sedimentary basins and usually developed in petroleum source rock;however,their origin remains debated.This study investigates the formation of BPCVs in the Permian carbonate rocks of the Khao Khwang Formation,central Thailand,through petrographic,geochemical,and isotopic analyses,along with total organic carbon(TOC)content assessment.Five samples,including 9 veins and 5 host rocks,were analyzed.The petrographic obser-vations show that the BPCVs exhibit cone-in-cone structure and beef vein and are classified as unitaxial veins.The geochemical analyses and stable isotope compositions suggest local fluid sources originated from inorganic carbonates and diagenetic formation fluids within the microbial methanogenic zone.The BPCVs have an averageδ13 CVPDB value of 3.04‰±0.30‰and an averageδ18 OVPDB value of 10.75‰±0.62‰,while the host rocks have an averageδ13 CVPDB value of 1.88‰±1.10‰and an averageδ18 OVPDB value of 10.77‰±0.39‰.The mineral compositions and element contents of the host rock and fibrous calcite veins are similar,with a strong negative relationship between calcium and other ele-ments.The rare earth element(REE)distribution patterns from the calcite veins are similar to the host rocks,with positive Ce anomalies and small positive Eu anomalies.Oxygen isotope data suggest vein formation at temperatures between 62℃and 75℃,corresponding to the onset of the oil window.The in-situ U-Pb dating indicates that fibrous calcite veins formed between the Early to Middle Permian period[(260.1±4.5)to(288.9±4.8)Ma)].Microstructural and geochemical evidence suggests that vein initiation resulted from fluid overpressure of a supersaturation of pore fluids within semi-consolidated sediments,with continuous vein dilatation driven by crystallization forces.This study illustrates that the BPCVs of the Khao Khwang Formation highlight significant potential in accurately assessing the evolution of hydrocarbon generation.
