Introduction:Inadequate blood pressure(BP)control is a significant challenge.Therapeutic decisions based on home blood pressure monitoring(HBPM)have been shown to lead to better blood pressure control compared to thos...Introduction:Inadequate blood pressure(BP)control is a significant challenge.Therapeutic decisions based on home blood pressure monitoring(HBPM)have been shown to lead to better blood pressure control compared to those based on office blood pressure(OBP)measurements alone.Objectives:To compare,over a five-year period,the annual BP control rates in hypertensive patients who were treated and monitored by the same cardiologists and who periodically used HBPM.Methodology:This was a multicenter study conducted with five cross-sectional analyses at annual intervals,with the first in 2019 and the last in 2023.OBP and HBPM measurements were performed according to current guidelines.Two cutoff points were considered for the analysis of BP control by OBP:<140/90 mmHg and<130/80 mmHg.For HBPM,the cutoff was<130/80 mmHg.Comparisons of quantitative variables between years were established using the t-test or chi-square test.A p-value<0.05 was considered significant.Results:A total of 8,890 individuals with a mean age of 63.3(±14.9)years were included,of whom 65.8%were women.A reduction in mean OBP values was observed between 2019-2020 and 2021-2022.There was also a reduction in the average number of antihypertensive medications used in 2020,with a mean of 1.99 medications taken that year.Compared to 2020,2022 showed an improvement in control rates for OBP<130/80 mmHg(31.5%vs.35.7%;p=0.008)and OBP<140/90 mmHg(58.7%vs.65.7%;p<0.001).Conclusion:Continuous monitoring by the same physician and the use of home measurement tools can lead to better BP control in hypertensive patients.展开更多
Objective: The aim of this study was to evaluate the sleep quality of medical students to identify the main factors that affect sleep patterns. Methods: According to the methodology, 154 students participated in the r...Objective: The aim of this study was to evaluate the sleep quality of medical students to identify the main factors that affect sleep patterns. Methods: According to the methodology, 154 students participated in the research, attending from the first to the sixth year of the course. The Pittsburg Sleep Quality Index questionnaire and the Epworth sleepiness scale were applied. Descriptive statistics techniques were applied and demonstrated in the form of tables and graphs. The comparison of variables was carried out using statistical tests. Results: The results showed that most students do not sleep very well. It was observed that 68.83% of a total of 106 students are bad sleepers. Conclusion: It is concluded that medical students sleep a low number of hours by period, which could interfere in impairment of attention, learning and memory formation, interfering in academic performance. On the other hand, they showed greater daytime sleepiness compared to the general population.展开更多
Objective: This study aimed to carry out a topographical analysis of frontal lobe executive function components in post-stroke patients. Methods: A descriptive, cross-sectional study. The assessment using the WCST (Wi...Objective: This study aimed to carry out a topographical analysis of frontal lobe executive function components in post-stroke patients. Methods: A descriptive, cross-sectional study. The assessment using the WCST (Wisconsin Card Sorting Test) included sixteen patients with a clinical diagnosis of CVA and frontal lobe impairment. Results from the two groups were compared (patients with right frontal lobe impairment and patients with left frontal lobe impairment). Statistical analysis was performed using the program “Statistical Package for Social Sciences” (SPSS) Version 20.0. For comparison between groups was used Mann-Whitney test and considered the alpha level of 0.05 on the statistically significant results. Results: There was no statistically significant difference between the groups, thus showing that executive functions are symmetrically distributed across the frontal lobes. Conclusion: Executive functions are symmetrically organized across the two frontal lobes, since the comparison between the groups did not demonstrate a statistically significant difference for any of the variables of WSCT.展开更多
Oxidation of lipids in various products,along with the growth of medically important pathogens,has led to a search for medicinal plants with antioxidant and antimicrobial activities.As a result,the aim of this study w...Oxidation of lipids in various products,along with the growth of medically important pathogens,has led to a search for medicinal plants with antioxidant and antimicrobial activities.As a result,the aim of this study was to evaluate the antioxidant and antibacterial activity of the essential oil of Eucalyptus globulus(EO-Eg).Antioxidant activity was assessed by using the 2,2-diphenyl-1-picrylhydrazyl hydrate(DPPH)assay method.Existing components were identified through gas chromatography-mass spectrometry(GC-MS)analysis.Antibacterial activity and minimum inhibitory concentration(MIC)were assessed by using the broth microdilution method with standard multidrug-resistant bacterial strains.The main EO-Eg compounds identified by GC-MS were isopulegol,citronellal,and citronellol,which are primarily used in the industrial sectors.EO-Eg demonstrated excellent antioxidant activity with an effective concentration(EC50)of 4.48μL/mL owing to the presence of phenolic compounds.Regarding antibacterial activity,the EO-Eg displayed a broad antimicrobial spectrum of antimicrobial activity across the different resistance phenotypes analyzed.The most notable antibacterial activity was observed against Staphylococcus aureus 169 MRSA(MIC=0.0625%).As a result,our findings suggest that EO-Eg has antioxidant and antibacterial potential against hospital-acquired multidrug-resistant pathogens,which may be correlated with its major components.展开更多
The </span><i><span style="font-family:Verdana;">vaquejada</span></i><span style="font-family:Verdana;"> race is a sport with animals which has the greatest soci...The </span><i><span style="font-family:Verdana;">vaquejada</span></i><span style="font-family:Verdana;"> race is a sport with animals which has the greatest socio-economic impact in Brazil and is responsible for generating an intense cultural and economic movement. However, this activity has been the subject of questions about well-being involving the environmental and mental comfort conditions offered to equine and cattle interactions. It is necessary to perform technical evaluations of the cattle involved on the basis of scientific study to better understand the processes of sport and, with this, promote their evolution on good welfare practices in the 21</span><sup><span style="font-family:Verdana;">st</span></sup><span style="font-family:Verdana;"> century. Therefore, to test the hypothesis that the use of the official rules of the </span><i><span style="font-family:Verdana;">vaquejada</span></i><span style="font-family:Verdana;"> where cattle use a protective harness on the tail protects the cattle’s tail from injuries in this region that compromise health. Before, during and after races, a study was developed that aimed to perform a general and radiological clinical evaluation in the proximal coccygeal region in cattle that ran in a modern cattle stall. Forty male bovines were evaluated (average: 2 year-old and 420 kg). Oxen were subjected to clinical and radiological examination before and after racing with official rules. Results of the clinical and radiological evaluations performed by veterinarians, did not observe clinical occurrences before and after the races in the 40 cattle evaluated. The increase in heart and respiratory rates was a reflection of temporary management stressors, as the animals returned to the feeding/rumination/interaction pattern after running in the rest pen. The radiographic findings in the tail, represented by the reduction of the intervertebral space and areas of subcutaneous radiolucency, suggest technical artifacts derived from the manipulation of the tail for proper positioning to perform the tests in the condition of retention in the corral. The partial fracture found by an evaluator showed signs of calcification and was accompanied by swelling in the soft tissue but without pain in the pre-run examination. It is concluded that the modern </span><i><span style="font-family:Verdana;">vaquejada</span></i><span style="font-family:Verdana;"> race, which meets the official rules, is not related to the increase in lesions in the locomotor apparatus or other evaluated tissues, including the tail.展开更多
Infrared thermography (IRT) has emerged for evaluation of animal welfare. To test the hypothesis that cattle subjected to vaquejada increased temperature in the eye (CLO) and tail due to physical effort, a research wa...Infrared thermography (IRT) has emerged for evaluation of animal welfare. To test the hypothesis that cattle subjected to vaquejada increased temperature in the eye (CLO) and tail due to physical effort, a research was developed that aimed to measure maximum surface temperature in the CLO and base of tail using IRT. Eighty Nellore cattle were used, which were subjected to physical effort in three periods (morning, afternoon and night). IRT was performed at CLO and base of tail, in rest pen/corral (control) and during the vaquejada (pre- and post-run). Tails’ analysis was divided in 3 points (E1, E2 and E3). ANOVA and Tukey’s test (p < 0.001) were used for analysis. Temperatures were higher in morning and afternoon and different from those at night on control (p < 0.001). During vaquejada with one run, CLO was higher in pre-run, followed by a slight reduction in post-run (p < 0.001). Analyzing temperatures variations at tail, higher temperatures were observed in the morning, followed by the evening and night (p < 0.001), but without differences within the pre- and post-run periods. Temperatures at tail’s points were higher in morning period in cattle with two runs (p < 0.001). Finally, it was concluded that there were no increases in CLO or at tail’s points after vaquejada races. The IRT method was efficient in determining surface temperatures in CLO and tail points in cattle under the same conditions and may be a good noninvasive method for clinical and welfare assessments.展开更多
文摘Introduction:Inadequate blood pressure(BP)control is a significant challenge.Therapeutic decisions based on home blood pressure monitoring(HBPM)have been shown to lead to better blood pressure control compared to those based on office blood pressure(OBP)measurements alone.Objectives:To compare,over a five-year period,the annual BP control rates in hypertensive patients who were treated and monitored by the same cardiologists and who periodically used HBPM.Methodology:This was a multicenter study conducted with five cross-sectional analyses at annual intervals,with the first in 2019 and the last in 2023.OBP and HBPM measurements were performed according to current guidelines.Two cutoff points were considered for the analysis of BP control by OBP:<140/90 mmHg and<130/80 mmHg.For HBPM,the cutoff was<130/80 mmHg.Comparisons of quantitative variables between years were established using the t-test or chi-square test.A p-value<0.05 was considered significant.Results:A total of 8,890 individuals with a mean age of 63.3(±14.9)years were included,of whom 65.8%were women.A reduction in mean OBP values was observed between 2019-2020 and 2021-2022.There was also a reduction in the average number of antihypertensive medications used in 2020,with a mean of 1.99 medications taken that year.Compared to 2020,2022 showed an improvement in control rates for OBP<130/80 mmHg(31.5%vs.35.7%;p=0.008)and OBP<140/90 mmHg(58.7%vs.65.7%;p<0.001).Conclusion:Continuous monitoring by the same physician and the use of home measurement tools can lead to better BP control in hypertensive patients.
文摘Objective: The aim of this study was to evaluate the sleep quality of medical students to identify the main factors that affect sleep patterns. Methods: According to the methodology, 154 students participated in the research, attending from the first to the sixth year of the course. The Pittsburg Sleep Quality Index questionnaire and the Epworth sleepiness scale were applied. Descriptive statistics techniques were applied and demonstrated in the form of tables and graphs. The comparison of variables was carried out using statistical tests. Results: The results showed that most students do not sleep very well. It was observed that 68.83% of a total of 106 students are bad sleepers. Conclusion: It is concluded that medical students sleep a low number of hours by period, which could interfere in impairment of attention, learning and memory formation, interfering in academic performance. On the other hand, they showed greater daytime sleepiness compared to the general population.
文摘Objective: This study aimed to carry out a topographical analysis of frontal lobe executive function components in post-stroke patients. Methods: A descriptive, cross-sectional study. The assessment using the WCST (Wisconsin Card Sorting Test) included sixteen patients with a clinical diagnosis of CVA and frontal lobe impairment. Results from the two groups were compared (patients with right frontal lobe impairment and patients with left frontal lobe impairment). Statistical analysis was performed using the program “Statistical Package for Social Sciences” (SPSS) Version 20.0. For comparison between groups was used Mann-Whitney test and considered the alpha level of 0.05 on the statistically significant results. Results: There was no statistically significant difference between the groups, thus showing that executive functions are symmetrically distributed across the frontal lobes. Conclusion: Executive functions are symmetrically organized across the two frontal lobes, since the comparison between the groups did not demonstrate a statistically significant difference for any of the variables of WSCT.
文摘Oxidation of lipids in various products,along with the growth of medically important pathogens,has led to a search for medicinal plants with antioxidant and antimicrobial activities.As a result,the aim of this study was to evaluate the antioxidant and antibacterial activity of the essential oil of Eucalyptus globulus(EO-Eg).Antioxidant activity was assessed by using the 2,2-diphenyl-1-picrylhydrazyl hydrate(DPPH)assay method.Existing components were identified through gas chromatography-mass spectrometry(GC-MS)analysis.Antibacterial activity and minimum inhibitory concentration(MIC)were assessed by using the broth microdilution method with standard multidrug-resistant bacterial strains.The main EO-Eg compounds identified by GC-MS were isopulegol,citronellal,and citronellol,which are primarily used in the industrial sectors.EO-Eg demonstrated excellent antioxidant activity with an effective concentration(EC50)of 4.48μL/mL owing to the presence of phenolic compounds.Regarding antibacterial activity,the EO-Eg displayed a broad antimicrobial spectrum of antimicrobial activity across the different resistance phenotypes analyzed.The most notable antibacterial activity was observed against Staphylococcus aureus 169 MRSA(MIC=0.0625%).As a result,our findings suggest that EO-Eg has antioxidant and antibacterial potential against hospital-acquired multidrug-resistant pathogens,which may be correlated with its major components.
文摘The </span><i><span style="font-family:Verdana;">vaquejada</span></i><span style="font-family:Verdana;"> race is a sport with animals which has the greatest socio-economic impact in Brazil and is responsible for generating an intense cultural and economic movement. However, this activity has been the subject of questions about well-being involving the environmental and mental comfort conditions offered to equine and cattle interactions. It is necessary to perform technical evaluations of the cattle involved on the basis of scientific study to better understand the processes of sport and, with this, promote their evolution on good welfare practices in the 21</span><sup><span style="font-family:Verdana;">st</span></sup><span style="font-family:Verdana;"> century. Therefore, to test the hypothesis that the use of the official rules of the </span><i><span style="font-family:Verdana;">vaquejada</span></i><span style="font-family:Verdana;"> where cattle use a protective harness on the tail protects the cattle’s tail from injuries in this region that compromise health. Before, during and after races, a study was developed that aimed to perform a general and radiological clinical evaluation in the proximal coccygeal region in cattle that ran in a modern cattle stall. Forty male bovines were evaluated (average: 2 year-old and 420 kg). Oxen were subjected to clinical and radiological examination before and after racing with official rules. Results of the clinical and radiological evaluations performed by veterinarians, did not observe clinical occurrences before and after the races in the 40 cattle evaluated. The increase in heart and respiratory rates was a reflection of temporary management stressors, as the animals returned to the feeding/rumination/interaction pattern after running in the rest pen. The radiographic findings in the tail, represented by the reduction of the intervertebral space and areas of subcutaneous radiolucency, suggest technical artifacts derived from the manipulation of the tail for proper positioning to perform the tests in the condition of retention in the corral. The partial fracture found by an evaluator showed signs of calcification and was accompanied by swelling in the soft tissue but without pain in the pre-run examination. It is concluded that the modern </span><i><span style="font-family:Verdana;">vaquejada</span></i><span style="font-family:Verdana;"> race, which meets the official rules, is not related to the increase in lesions in the locomotor apparatus or other evaluated tissues, including the tail.
文摘Infrared thermography (IRT) has emerged for evaluation of animal welfare. To test the hypothesis that cattle subjected to vaquejada increased temperature in the eye (CLO) and tail due to physical effort, a research was developed that aimed to measure maximum surface temperature in the CLO and base of tail using IRT. Eighty Nellore cattle were used, which were subjected to physical effort in three periods (morning, afternoon and night). IRT was performed at CLO and base of tail, in rest pen/corral (control) and during the vaquejada (pre- and post-run). Tails’ analysis was divided in 3 points (E1, E2 and E3). ANOVA and Tukey’s test (p < 0.001) were used for analysis. Temperatures were higher in morning and afternoon and different from those at night on control (p < 0.001). During vaquejada with one run, CLO was higher in pre-run, followed by a slight reduction in post-run (p < 0.001). Analyzing temperatures variations at tail, higher temperatures were observed in the morning, followed by the evening and night (p < 0.001), but without differences within the pre- and post-run periods. Temperatures at tail’s points were higher in morning period in cattle with two runs (p < 0.001). Finally, it was concluded that there were no increases in CLO or at tail’s points after vaquejada races. The IRT method was efficient in determining surface temperatures in CLO and tail points in cattle under the same conditions and may be a good noninvasive method for clinical and welfare assessments.
