Anacardium occidentale L., Anacardiaceae, is frequently used to treat infections. We evaluated the antimicrobial and antioxidant activity of extracts obtained from aerial parts of the plant in comparison with the extr...Anacardium occidentale L., Anacardiaceae, is frequently used to treat infections. We evaluated the antimicrobial and antioxidant activity of extracts obtained from aerial parts of the plant in comparison with the extract prepared with the flowers. Ethanol extracts of the leaves (EEL), stem bark (EEB), and flowers (EEF) were prepared separately. The antimicrobial activity was evaluated by agar diffusion and broth dilution methods. The minimum bactericidal and fungicidal concentrations were determined against: Streptococcus mutans, Lactobacillus acidophilus, Staphylococcus aureus, MRSA, Enterococcus faecalis, Streptococcus pyogenes, Pseudomonas aeruginosa, Proteus mirabilis, Escherichia coli, Klebsiella pneumoniae, Helicobacter pylori, Salmonella choleraesuis, Candida albicans, and Candida tropicalis. The antioxidant activity of the extracts was evaluated based on their scavenger capacity of 2,2-diphenyl-1-picrylhydrazyle. The phytochemical profile was analyzed by colorimetric methods and by HPLC with UV detection. All extracts exhibited antioxidant and antimicrobial activity. Although, the EEF was the most effective since it inhibited the growth of all 14 microorganisms tested. Anacardic and galic acids were identified in all extracts as well phenolic compounds, triterpenes, flavones and xanthones. In conclusion, the extracts obtained from the aerial parts of A. occidentale, mainly the extract of flowers that was the most effective, are rich in bioactive metabolites that exert a potent antioxidant and antimicrobial effect. Taken together, the results indicate an important biotechnological potential of A. occidentale as a source of compounds with broad-spectrum antimicrobial and of antioxidant activity to be used in the food and cosmetics industry.展开更多
During COVID-19,the repercussions on scholar dynamics,functioning and structure were inevitable,causing an impact on groups that,historically,are minority in relation to the scope of school inclusion policies,such as ...During COVID-19,the repercussions on scholar dynamics,functioning and structure were inevitable,causing an impact on groups that,historically,are minority in relation to the scope of school inclusion policies,such as students diagnosed with autism spectrum disorder(ASD).This scenario is followed by educational phenomena in the face of which School Psychology has collaborated with the advancement of research and knowledge production.This qualitative study,based on Historical-Cultural Psychology and Critical School Psychology,analyzed the role of the school psychologist in monitoring students diagnosed with ASD in the context of regular school during the pandemic.The following procedures were conducted:application of an online questionnaire;and semi-structured interviews with four school psychologists.As a result,three zones of shared meanings were built:the claim for the right to education with support and adaptations;the psychologist as the great savior of inclusion;the non-total inclusion that denounces the structure of injustice by school.The information suggests that professional performance was hampered by different obstacles in the pandemic,such as the difficulty imposed by school,overload of demands,and impasses in the implementation of inclusion historically experienced at school,revealing that the school structure still carries historical consequences of exclusion.These shared meanings have demanded a professional performance with more effort,resistance,and strategies that accept the demands of school inclusion,providing collective mobilization,together with school actors,capable of breaking down barriers,especially those related to capacitist concepts.展开更多
Previous studies have investigated the efficiency in teaching listener and speaker repertoires in children diagnosed with autism spectrum disorder(ASD).Some investigations focused on listener responding by function,fe...Previous studies have investigated the efficiency in teaching listener and speaker repertoires in children diagnosed with autism spectrum disorder(ASD).Some investigations focused on listener responding by function,feature,and class(LRFFC)and intraverbal by function,feature,and class(FFC).For some children,teaching intraverbal FFC was more efficient because it resulted in a better emergence effect of a related untaught repertoire(LRFFC).For other children,teaching LRFFC along with tacting pictures was more efficient,resulting in a better emergence effect of a related untaught repertoire(intraverbal FFC).In these cases,it is not clear whether the tact increased the efficiency of LRFFC training because a comparison with a condition in which tacts were not required was not conducted.This investigation consisted of a replication with two children diagnosed with ASD.Three instructional sequences were compared:teaching LRFFC-probing intraverbal;teaching LRFFC+tacts-probing intraverbal;teaching intraverbal-probing LRFFC.For a child,all sequences were equally efficient because all related untaught repertoires emerged without errors.However,the acquisition of intraverbals during training occurred with variability.In the case of the second child,the most efficient sequence consisted of teaching intraverbals,resulting in the emergence of LRFFC without errors.In both cases of teaching LRFFC,the emergence of related intraverbals was partial and acquisition of the trained repertoires occurred with variability.The case that did not demand tact responses was slightly more efficient.Data were discussed in the sense that the best instructional sequence may vary from learner to learner.展开更多
Currently, there are significant investments in the study of distributed generation, including solar energy by the photovoltaic conversion method. Basically, a cell directly converts solar energy to electricity. For t...Currently, there are significant investments in the study of distributed generation, including solar energy by the photovoltaic conversion method. Basically, a cell directly converts solar energy to electricity. For this, static converters are required. However, relevant issues arise in this process: point of maximum efficiency of module generation, strategy of control of the flow of energy to the network. The aim of this work is to monitor the main variables of a photovoltaic system, specifically the voltage and current module and their derivates. The goal is to implement the maximum power tracking technique using Fuzzy logic. In addition, the energy provided by the cell will be employed in an inverter stage that can operate as an active filter, voltage regulator, or generator of reactive and active power. The feasibility of using Fuzzy logic will also be studied. The first stage of this work involves parameterization and simulation of photovoltaic modules. The initial study examines the compatibility of a commercial module and its catalog data with the results of simulation. The simulated I-V characteristics show almost identical results to the catalog data. In sequence, a boost or lift DC-DC converter is employed to emulate variable load for maximum power transfer.展开更多
Nosocomial infections have been common in health services in Brazil.Among them,pneumonia is very highlighted due to the comorbidity that usually affects intensive treatment unit(ITU)patients,and due to the need for en...Nosocomial infections have been common in health services in Brazil.Among them,pneumonia is very highlighted due to the comorbidity that usually affects intensive treatment unit(ITU)patients,and due to the need for endotracheal intubation.The aim of this study was to determine the resistance profile of bacteria isolated from ITU patients with pneumonia in a public hospital in S?o Luis,an important city in the Brazilian pre-Amazon region.Bacteria strains were obtained from tracheal aspiration and collected for diagnosis as well for phenotypic characterization.Standards culture media,such as blood and MacConkey agar,were used to isolate clinical strains.Automatized Vitek 2 method was used to identify strains and disc diffusion method(Kirby-Bauer)was performed to determine the antimicrobial susceptibility profile.During study,eighty-eight patients were diagnosed with pneumonia,caused by more than 20 different bacteria.Among them,P.aeruginosa(28%),Acinetobacter baumannii(20%),Coagulase-negative Staphylococci(19%),Staphylococcus aureus(8%)and Klebsiella pneumoniae(7%)were the most prevalent microorganisms.Regarding to the resistance,antimicrobial susceptibility test showed that majority of Gram-negative bacteria presented resistance to ampicillin.In Gram-positive bacteria there was a high resistance to ampicillin,penicillin,ciprofloxacin,clindamycin and erythromycin.This study showed a high prevalence of bacteria resistance in ITU patients in a public hospital.Although P.aeruginosa was the most frequent pathogen,it was possible to find other pathogens that were not recurrent,such as Enterobacter spp.,Proteus mirabilis and Providencia stuartii.Regarding antimicrobials,the results showed a high resistance to several antimicrobials.展开更多
Punica granatum L.possesses known antimicrobial and anti-inflammatory actions.Preparations of different parts of this plant have been commonly used in the folk medicine to prevent and treat infections;and studies have...Punica granatum L.possesses known antimicrobial and anti-inflammatory actions.Preparations of different parts of this plant have been commonly used in the folk medicine to prevent and treat infections;and studies have supported the use of P.granatum extracts for this purpose.However,little is known of the effects of P.granatum-derived fractions in severe infectious diseases such as sepsis.Here,we investigated the actions of the hexane fraction(HF),rich in lipophilic compounds,obtained from the leaves of this plant,in a murine model of polymicrobial sepsis.Oral pre-treatment with HF increased mortality in septic mice.The same animals presented with lower levels of interleukin-6,nitric oxide and hydrogen peroxide in their peritoneal lavage samples than vehicle mice.HF also increased polymorphonuclear cell accumulation in to the peritoneum of mice with sepsis.Macrophage-derived nitric oxide upon lipopolysaccharide stimuli was markedly reduced by incubation with HF.Diterpenes,triterpenes,phytosterols,vitamin E and ascorbyl palmitate were detected in the HF.These results indicate that P.granatum leaf lipophilic fractions may worsen sepsis outcome.This effect may be associated with its bioactive compounds which act synergistically or not,increasing sepsis mortality in vivo.展开更多
文摘Anacardium occidentale L., Anacardiaceae, is frequently used to treat infections. We evaluated the antimicrobial and antioxidant activity of extracts obtained from aerial parts of the plant in comparison with the extract prepared with the flowers. Ethanol extracts of the leaves (EEL), stem bark (EEB), and flowers (EEF) were prepared separately. The antimicrobial activity was evaluated by agar diffusion and broth dilution methods. The minimum bactericidal and fungicidal concentrations were determined against: Streptococcus mutans, Lactobacillus acidophilus, Staphylococcus aureus, MRSA, Enterococcus faecalis, Streptococcus pyogenes, Pseudomonas aeruginosa, Proteus mirabilis, Escherichia coli, Klebsiella pneumoniae, Helicobacter pylori, Salmonella choleraesuis, Candida albicans, and Candida tropicalis. The antioxidant activity of the extracts was evaluated based on their scavenger capacity of 2,2-diphenyl-1-picrylhydrazyle. The phytochemical profile was analyzed by colorimetric methods and by HPLC with UV detection. All extracts exhibited antioxidant and antimicrobial activity. Although, the EEF was the most effective since it inhibited the growth of all 14 microorganisms tested. Anacardic and galic acids were identified in all extracts as well phenolic compounds, triterpenes, flavones and xanthones. In conclusion, the extracts obtained from the aerial parts of A. occidentale, mainly the extract of flowers that was the most effective, are rich in bioactive metabolites that exert a potent antioxidant and antimicrobial effect. Taken together, the results indicate an important biotechnological potential of A. occidentale as a source of compounds with broad-spectrum antimicrobial and of antioxidant activity to be used in the food and cosmetics industry.
文摘During COVID-19,the repercussions on scholar dynamics,functioning and structure were inevitable,causing an impact on groups that,historically,are minority in relation to the scope of school inclusion policies,such as students diagnosed with autism spectrum disorder(ASD).This scenario is followed by educational phenomena in the face of which School Psychology has collaborated with the advancement of research and knowledge production.This qualitative study,based on Historical-Cultural Psychology and Critical School Psychology,analyzed the role of the school psychologist in monitoring students diagnosed with ASD in the context of regular school during the pandemic.The following procedures were conducted:application of an online questionnaire;and semi-structured interviews with four school psychologists.As a result,three zones of shared meanings were built:the claim for the right to education with support and adaptations;the psychologist as the great savior of inclusion;the non-total inclusion that denounces the structure of injustice by school.The information suggests that professional performance was hampered by different obstacles in the pandemic,such as the difficulty imposed by school,overload of demands,and impasses in the implementation of inclusion historically experienced at school,revealing that the school structure still carries historical consequences of exclusion.These shared meanings have demanded a professional performance with more effort,resistance,and strategies that accept the demands of school inclusion,providing collective mobilization,together with school actors,capable of breaking down barriers,especially those related to capacitist concepts.
文摘Previous studies have investigated the efficiency in teaching listener and speaker repertoires in children diagnosed with autism spectrum disorder(ASD).Some investigations focused on listener responding by function,feature,and class(LRFFC)and intraverbal by function,feature,and class(FFC).For some children,teaching intraverbal FFC was more efficient because it resulted in a better emergence effect of a related untaught repertoire(LRFFC).For other children,teaching LRFFC along with tacting pictures was more efficient,resulting in a better emergence effect of a related untaught repertoire(intraverbal FFC).In these cases,it is not clear whether the tact increased the efficiency of LRFFC training because a comparison with a condition in which tacts were not required was not conducted.This investigation consisted of a replication with two children diagnosed with ASD.Three instructional sequences were compared:teaching LRFFC-probing intraverbal;teaching LRFFC+tacts-probing intraverbal;teaching intraverbal-probing LRFFC.For a child,all sequences were equally efficient because all related untaught repertoires emerged without errors.However,the acquisition of intraverbals during training occurred with variability.In the case of the second child,the most efficient sequence consisted of teaching intraverbals,resulting in the emergence of LRFFC without errors.In both cases of teaching LRFFC,the emergence of related intraverbals was partial and acquisition of the trained repertoires occurred with variability.The case that did not demand tact responses was slightly more efficient.Data were discussed in the sense that the best instructional sequence may vary from learner to learner.
文摘Currently, there are significant investments in the study of distributed generation, including solar energy by the photovoltaic conversion method. Basically, a cell directly converts solar energy to electricity. For this, static converters are required. However, relevant issues arise in this process: point of maximum efficiency of module generation, strategy of control of the flow of energy to the network. The aim of this work is to monitor the main variables of a photovoltaic system, specifically the voltage and current module and their derivates. The goal is to implement the maximum power tracking technique using Fuzzy logic. In addition, the energy provided by the cell will be employed in an inverter stage that can operate as an active filter, voltage regulator, or generator of reactive and active power. The feasibility of using Fuzzy logic will also be studied. The first stage of this work involves parameterization and simulation of photovoltaic modules. The initial study examines the compatibility of a commercial module and its catalog data with the results of simulation. The simulated I-V characteristics show almost identical results to the catalog data. In sequence, a boost or lift DC-DC converter is employed to emulate variable load for maximum power transfer.
文摘Nosocomial infections have been common in health services in Brazil.Among them,pneumonia is very highlighted due to the comorbidity that usually affects intensive treatment unit(ITU)patients,and due to the need for endotracheal intubation.The aim of this study was to determine the resistance profile of bacteria isolated from ITU patients with pneumonia in a public hospital in S?o Luis,an important city in the Brazilian pre-Amazon region.Bacteria strains were obtained from tracheal aspiration and collected for diagnosis as well for phenotypic characterization.Standards culture media,such as blood and MacConkey agar,were used to isolate clinical strains.Automatized Vitek 2 method was used to identify strains and disc diffusion method(Kirby-Bauer)was performed to determine the antimicrobial susceptibility profile.During study,eighty-eight patients were diagnosed with pneumonia,caused by more than 20 different bacteria.Among them,P.aeruginosa(28%),Acinetobacter baumannii(20%),Coagulase-negative Staphylococci(19%),Staphylococcus aureus(8%)and Klebsiella pneumoniae(7%)were the most prevalent microorganisms.Regarding to the resistance,antimicrobial susceptibility test showed that majority of Gram-negative bacteria presented resistance to ampicillin.In Gram-positive bacteria there was a high resistance to ampicillin,penicillin,ciprofloxacin,clindamycin and erythromycin.This study showed a high prevalence of bacteria resistance in ITU patients in a public hospital.Although P.aeruginosa was the most frequent pathogen,it was possible to find other pathogens that were not recurrent,such as Enterobacter spp.,Proteus mirabilis and Providencia stuartii.Regarding antimicrobials,the results showed a high resistance to several antimicrobials.
文摘Punica granatum L.possesses known antimicrobial and anti-inflammatory actions.Preparations of different parts of this plant have been commonly used in the folk medicine to prevent and treat infections;and studies have supported the use of P.granatum extracts for this purpose.However,little is known of the effects of P.granatum-derived fractions in severe infectious diseases such as sepsis.Here,we investigated the actions of the hexane fraction(HF),rich in lipophilic compounds,obtained from the leaves of this plant,in a murine model of polymicrobial sepsis.Oral pre-treatment with HF increased mortality in septic mice.The same animals presented with lower levels of interleukin-6,nitric oxide and hydrogen peroxide in their peritoneal lavage samples than vehicle mice.HF also increased polymorphonuclear cell accumulation in to the peritoneum of mice with sepsis.Macrophage-derived nitric oxide upon lipopolysaccharide stimuli was markedly reduced by incubation with HF.Diterpenes,triterpenes,phytosterols,vitamin E and ascorbyl palmitate were detected in the HF.These results indicate that P.granatum leaf lipophilic fractions may worsen sepsis outcome.This effect may be associated with its bioactive compounds which act synergistically or not,increasing sepsis mortality in vivo.
