The rapid growth in available network bandwidth has directly contributed to an exponential increase in mobile data traffic,creating significant challenges for network energy consumption.Also,with the extraordinary gro...The rapid growth in available network bandwidth has directly contributed to an exponential increase in mobile data traffic,creating significant challenges for network energy consumption.Also,with the extraordinary growth of mobile communications,the data traffic has dramatically expanded,which has led to massive grid power consumption and incurred high operating expenditure(OPEX).However,the majority of current network designs struggle to efficientlymanage a massive amount of data using little power,which degrades energy efficiency performance.Thereby,it is necessary to have an efficient mechanism to reduce power consumption when processing large amounts of data in network data centers.Utilizing renewable energy sources to power the Cloud Radio Access Network(C-RAN)greatly reduces the need to purchase energy from the utility grid.In this paper,we propose a bandwidth-aware hybrid energypowered C-RAN that focuses on throughput and energy efficiency(EE)by lowering grid usage,aiming to enhance the EE.This paper examines the energy efficiency,spectral efficiency(SE),and average on-grid energy consumption,dealing with the major challenges of the temporal and spatial nature of traffic and renewable energy generation across various network setups.To assess the effectiveness of the suggested network by changing the transmission bandwidth,a comprehensive simulation has been conducted.The numerical findings support the efficacy of the suggested approach.展开更多
Background:Recent evidence suggests continuous bouts of physical activity(PA)are associated with longevity.We hypothesized the risk of mortality would be lower when the most active minutes of the day were in a continu...Background:Recent evidence suggests continuous bouts of physical activity(PA)are associated with longevity.We hypothesized the risk of mortality would be lower when the most active minutes of the day were in a continuous bout.Methods:PA was assessed using accelerometery in UK Biobank participants.The intensity of the most active continuous(MXCONT)and accumulated(MX)X min of the day,and their ratio(MXRATIO=MXCONT/MX),were determined.MXRATIO indicates how the most active minutes of the day are accumulated,ranging from a single continuous bout through to sporadic accumulation spread across the day.Durations(X)considered ranged from 1 to 20 min.The outcome was mortality.Results:In total,94,541 participants(56.5% female)were included.Over a median(interquartile range)follow-up of 6.9(6.3,7.4)years,2649(2.8%)deaths occurred.Intensity moderated the association between how the most active minutes of the day were accumulated and mortality risk,expressed relative to sporadically accumulated moderate PA.If the most active minutes were of moderate intensity,the risk of mortality was halved for continuous compared to sporadic accumulation,irrespective of duration;if the most active minutes were of vigorous intensity,a continuous bout was associated with the lowest risk for durations under 5 min(e.g.,3 min:hazard ratio(HR)=0.27,95% confidence interval(95%CI):0.21-0.34),while sporadic accumulation was associated with the lowest risk for durations beyond 5 min(HR=0.11,95%CI:0.08-0.15 for the most active 20 min).Conclusion:Optimal PA patterns for reducing mortality differ by intensity and duration.For moderate-intensity PA,a lower mortality risk may be optimized by prioritizing continuous PA for up to 20 min.However,for vigorous-intensity PA,multiple short bouts(<5 min)may be optimal.This suggests tailored PA recommendations may enhance longevity benefits.展开更多
We examine technology ETF and uncertainty index(VIX,GVZ,and OVZ)spillover dynamics and quantile frequency interconnectedness across market states.This study is the first to use quantile-frequency spillover,quadruple w...We examine technology ETF and uncertainty index(VIX,GVZ,and OVZ)spillover dynamics and quantile frequency interconnectedness across market states.This study is the first to use quantile-frequency spillover,quadruple wavelet coherence,and wavelet quantile correlation methodologies to facilitate these analyses.The total connectedness index value is 70%,which is much higher in both the upper and lower quantiles.Under normal market conditions,short-term connectedness significantly exceeds long-term connectedness.Levels of ETF-uncertainty indicator connectedness increase under extreme market conditions;most technology ETFs are net spillover transmitters and uncertainty indices net spillover receivers,indicating the contagion risk of ETF investments.We show that while greater ETF-uncertainty index connectedness may benefit portfolio diversification,large fluctuations in technology EFTs can result in financial instability due to high market volatility.In the long term,the joint effects of uncertainty indices on ETFs are significant,with negative correlations between ETFs and uncertainties at different frequencies,supporting the potential role of uncertainty indices in hedging technology ETF portfolio risks.Dynamic portfolio rebalancing,scenario analysis,and stress testing may help to manage the effects of high connectedness.展开更多
As living standards improve,the energy consumption for regulating indoor temperature keeps increasing.Windows,in particular,enhance indoor brightness but also lead to increased energy loss,especially in sunny weather....As living standards improve,the energy consumption for regulating indoor temperature keeps increasing.Windows,in particular,enhance indoor brightness but also lead to increased energy loss,especially in sunny weather.Developing a product that can maintain indoor brightness while reducing energy consumption is a challenge.We developed a facile,spectrally selective transparent ultrahigh-molecular-weight polyethylene composite film to address this trade-off.It is based on a blend of antimony-doped tin oxide and then spin-coated hydrophobic fumed silica,achieving a high visible light transmittance(>70%)and high shielding rates for ultraviolet(>90%)and near-infrared(>70%).When applied to the acrylic window of containers and placed outside,this film can cause a 10℃ temperature drop compared to a pure polymer film.Moreover,in building energy simulations,the annual energy savings could be between 14.1%~31.9%per year.The development of energy-efficient and eco-friendly transparent films is crucial for reducing energy consumption and promoting sustainability in the window environment.展开更多
Aflatoxin B1(AFB1)is a toxic fungal metabolite that contaminates almonds from cultivation to harvesting.It leads to chronic health problems and significant economic loss to the producers.Therefore,a fast and non-invas...Aflatoxin B1(AFB1)is a toxic fungal metabolite that contaminates almonds from cultivation to harvesting.It leads to chronic health problems and significant economic loss to the producers.Therefore,a fast and non-invasive detection technique is crucial for safeguarding food safety by swiftly identifying and eliminating contaminated almonds from the supply chain.Hyperspectral imaging has been explored as a potential non-destructive technology for detecting AFB1.However,the diverse geometries of almonds present a significant challenge on acquired images,thereby impacting the accuracy of the developed prediction and classification models.This study investigates the effectiveness of short-wave infrared(SwIR)hyperspectral imaging combined with deep learning for detecting AFB1 in almonds of varying geometries.Initially,partial least squares regression(PLSR)and support vector machine(SvM)regression models were evaluated for quantification,while SVM and quadratic discriminant analysis(QDA)classifiers were applied for classification.The results indicated that spectral responses varied with almond thickness,making quantification models unreliable for industrial applications.The Competitive Adaptive Reweighted Sampling(CARS)algorithm was employed to identify key spectral features for developing multi-spectral AFB1 classification models to evaluate the feasibility of high-speed,accurate in-line detection.The deep learning approach significantly outperformed traditional machine learning models,with the pre-trained Inception V3 network achieving a cross-validation accuracy of 84.82%,an F1-score of 0.8522,and an area under curve of 0.893.These findings highlight the superiority of deep learning-based hyperspectral imaging for accurate and reliable AFB1 detection in almonds with diverse shapes and thicknesses.展开更多
The Tasmanian microcontinent,situated along the East Gondwana accretionary margin during the late Neoproterozoic and early Palaeozoic,contains an unequivocal high-pressure metamorphic record comprising key information...The Tasmanian microcontinent,situated along the East Gondwana accretionary margin during the late Neoproterozoic and early Palaeozoic,contains an unequivocal high-pressure metamorphic record comprising key information pertaining to the geodynamics of subduction along the margin.Subduction of the Tasmanian microcontinent is interpreted by some as a response to back-arc basin inversion prior to ophiolite obduction and high-pressure metamorphism during the Cambrian Tyennan Orogeny.However,thermobarometric evidence in support of such a model from rocks once positioned on the subducting continental margin is lacking.Despite occurrences of eclogite-facies mineral assemblages in the strongly deformed Tyennan Region of western Tasmania,garnet-bearing quartzofeldspathic assemblages documented in metasedimentary lithologies from the remote south-west coast of Tasmania have been interpreted as an expression of low-to moderate-pressure metamorphism.We report a strongly overprinted chlorite-quartz-garnet-bearing assemblage from the southern Tyennan Region(Nye Bay)which shows evidence for high-pressure metamorphism.Coarse-grained garnet porphyroblasts contain inclusions of kyanite,muscovite,and rutile,and yield in-situ Lu-Hf dates of c.520 Ma.The cm-scale garnet porphyroblasts are zoned in the major and trace elements,preserving core-rim compositional gradients reflecting garnet growth up-pressure.Aided by mineral equilibria forward modelling,the garnet rim compositions and the Zr content of Cambrian rutile constrain peak metamorphic conditions of∼17.5-19 kbar and∼780-820℃,equivalent to warm subduction thermal gradients between 410-470℃/GPa.Garnet core compositions and the Ti content of quartz inclusions in the garnet cores constrain the pressures and temperatures for garnet nucleation to∼6-7 kbar and∼560-580℃,corresponding to relatively high prograde thermal gradients between 800-965℃/GPa.The thermal gradients determined from the south-west Tasmanian metamorphic record provide a direct window into the progressive evolution of the thermal state of the Cambrian subduction system,with the physical conditions of garnet nucleation potentially reflecting those of subduction initiation.The corresponding warm thermal gradients provide evidence for subduction initiation driven by the collapse of a pre-orogenic back-arc.This interpretation is consistent with an existing tectonic model for the Tyennan Orogeny which proposes a back-arc basin origin for the protoliths to the western Tasmanian sub-ophiolitic metamorphic sole.展开更多
From a quantum chemistry standpoint,the impact of the structural properties of the compounds on activated carbon’s adsorption ability was specifically investigated.The compounds whose adsorption behavior followed the...From a quantum chemistry standpoint,the impact of the structural properties of the compounds on activated carbon’s adsorption ability was specifically investigated.The compounds whose adsorption behavior followed the Langmuir isotherm model were selected as the research objects.An optimal quantitative structure-activity relationship(QSAR)model was built by using the multiple linear regression(MLR)method,with the saturation adsorption capacity Q_(m) from the Langmuir adsorption isotherm as the response variable and the structural parameters of 50 organic compounds as independent variables.The results show that the optimal model exhibits good stability,reliability and robustness,with a regression coefficient R^(2)of 0.88,an adjusted regression coefficient R_(adj)^(2) of 0.87,an internal validation coefficient q^(2) of 0.81,and an external validation coefficient Q_(ext)^(2) of 0.68.The variables included in the optimal model indicate that the polarity of the molecule,the molecular potential energy,and the stability and bonding strength of the organic compound are the main factors affecting the adsorption on activated carbon.The results provide key information for predicting the adsorption capacity of organic compounds on activated carbon and offer a theoretical reference for adsorption treatment in water environments.展开更多
Device-based measurements are recommended to improve population-based physical activity(PA)surveillance.1,2However,implementation remains challenging due to lack of consensus on analytical methods,and the most widely ...Device-based measurements are recommended to improve population-based physical activity(PA)surveillance.1,2However,implementation remains challenging due to lack of consensus on analytical methods,and the most widely used“generic”(absolute intensity)cut-point approach has limited generalisability to population-level free-living data.Further,current methods generally fail to account for differences in people's physical capacity.展开更多
Ground fissure,as a common geo-hazard,impairs the integrity of the site soil and affects the seismic performance of engineering structures.In this paper,a finite element(FE)model for subway stations in a ground fissur...Ground fissure,as a common geo-hazard,impairs the integrity of the site soil and affects the seismic performance of engineering structures.In this paper,a finite element(FE)model for subway stations in a ground fissure area was developed and validated by using experimental results.Numerical analyses were conducted to investigate the seismic response and failure mode of subway stations in a ground fissure area with different locations.Effects of ground fissure on deformations and internal forces of a station,soil pressures and soil plastic strains were discussed.The results showed that the seismic response of the station was significantly amplified by the ground fissure,and stations in the ground fissure area displayed obvious rocking deformation during earthquakes as compared to those in the area without fissures.It also was found that the soil yielding around the station,the dislocation occurring in the ground fissure area,and the dynamic amplification effect were more significant under vertical ground motion,which weakened the station’s ductility and accelerated its destruction process.展开更多
Background Higher accelerometer-assessed volume and intensity of physical activity(PA)have been associated with a longer life expectancy but can be difficult to translate into recommended doses of PA.We aimed to:(a)im...Background Higher accelerometer-assessed volume and intensity of physical activity(PA)have been associated with a longer life expectancy but can be difficult to translate into recommended doses of PA.We aimed to:(a)improve interpretability by producing UK Biobank age-referenced centiles for PA volume and intensity;(b)inform public-health messaging by examining how adding recommended quantities of moderate and vigorous PA affect PA volume and intensity.Methods 92,480 UK Biobank participants aged 43-80 years with wrist-worn accelerometer data were included.Average acceleration and intensity gradient were derived as proxies for PA volume and intensity.We generated sex-specific centile curves using Generalized Additive Models for Location Scale and Shape(GAMLSS)and modeled the effect of adding moderate(walking)or vigorous(running)activity on the combined change in the volume and intensity centiles(change in PA profile).Results In men,volume was lower as age increased while intensity was lower after age 55;in women,both volume and intensity were lower as age increased.Adding 150 min of moderate PA weekly(5×30 min walking)increased the PA profile by 4 percentage points.Defining moderate PA as brisk walking approximately doubled the increase(9 percentage points)while 75 min of vigorous PA weekly(5×15 min running)trebled the increase(13 percentage points).Conclusion These UK Biobank reference centiles provide a benchmark for interpretation of accelerometer data.Application of our translational methods demonstrate that meeting PA guidelines through shorter duration vigorous activity is more beneficial to the PA profile(volume and intensity)than longer duration moderate activity.展开更多
Background:Cardiorespiratory fitness(CRF)is a powerful health marker recommended by the American Heart Association as a clinical vital sign.Comparing the predictive validity of objectively measured CRF(the"gold s...Background:Cardiorespiratory fitness(CRF)is a powerful health marker recommended by the American Heart Association as a clinical vital sign.Comparing the predictive validity of objectively measured CRF(the"gold standara")and estimated CRF is clinically relevant because estimated CRF is more feasible.Our objective was to meta-analyze cohort studies to compare the associations of objectively measured,exerciseestimated,and non-exercise-estimated CRF with all-cause and cardiovascular disease(CVD)mortality in adults.Methods:Systematic searches were conducted in 9 databases(MEDLINE,SPORTDiscus,Embase,Scopus,PsycINFO,Web of Science,PubMed,CINAHL,and the Cochrane Library)up to April 11,2024.We included full-text refereed cohort studies published in English that quantified the association(using risk estimates with 95%confidence intervals(95%CIs))of objectively measured,exercise-estimated,and non-exercise-estimated CRF with all-cause and CVD mortality in adults.CRF was expressed as metabolic equivalents(METs)of task.Pooled relative risks(RR)for all-cause and CVD mortality per 1-MET(3.5 mL/kg/min)higher level of CRF were quantified using random-effects models.Results:Forty-two studies representing 35 cohorts and 3,813,484 observations(81%male)(362,771 all-cause and 56,471 CVD deaths)were included.The pooled RRs for all-cause and CVD mortality per higher MET were 0.86(95%CI:0.83-0.88)and 0.84(95%CI:0.80-0.87),respectively.For both all-cause and CVD mortality,there were no statistically significant differences in RR per higher MET between objectively measured(RR range:0.86-0.90)and maximal exercise-estimated(RR range:0.85-0.86),submaximal exercise-estimated(RR range:0.91-0.94),and non-exercise-estimated CRF(RR range:0.81-0.85).Conclusion:Objectively measured and estimated CRF showed similar dose-response associations for all-cause and CVD mortality in adults.Estimated CRF could provide a practical and robust alternative to objectively measured CRF for assessing mortality risk across diverse populations.Our findings underscore the health-related benefits of higher CRF and advocate for its integration into clinical practice to enhance risk stratification.展开更多
文摘The rapid growth in available network bandwidth has directly contributed to an exponential increase in mobile data traffic,creating significant challenges for network energy consumption.Also,with the extraordinary growth of mobile communications,the data traffic has dramatically expanded,which has led to massive grid power consumption and incurred high operating expenditure(OPEX).However,the majority of current network designs struggle to efficientlymanage a massive amount of data using little power,which degrades energy efficiency performance.Thereby,it is necessary to have an efficient mechanism to reduce power consumption when processing large amounts of data in network data centers.Utilizing renewable energy sources to power the Cloud Radio Access Network(C-RAN)greatly reduces the need to purchase energy from the utility grid.In this paper,we propose a bandwidth-aware hybrid energypowered C-RAN that focuses on throughput and energy efficiency(EE)by lowering grid usage,aiming to enhance the EE.This paper examines the energy efficiency,spectral efficiency(SE),and average on-grid energy consumption,dealing with the major challenges of the temporal and spatial nature of traffic and renewable energy generation across various network setups.To assess the effectiveness of the suggested network by changing the transmission bandwidth,a comprehensive simulation has been conducted.The numerical findings support the efficacy of the suggested approach.
基金funded by UK Research and Innovation(research which commenced between October 1,2020-March 31,2021,Grant ref MC_PC_20029April 1,2021-September 31,2022,Grant ref MC_PC_20058)supported by the National Institute for Health Research(NIHR)Leicester Biomedical Research Centre and NIHR Applied Research CollaborationEast Midlands(ARC-EM)。
文摘Background:Recent evidence suggests continuous bouts of physical activity(PA)are associated with longevity.We hypothesized the risk of mortality would be lower when the most active minutes of the day were in a continuous bout.Methods:PA was assessed using accelerometery in UK Biobank participants.The intensity of the most active continuous(MXCONT)and accumulated(MX)X min of the day,and their ratio(MXRATIO=MXCONT/MX),were determined.MXRATIO indicates how the most active minutes of the day are accumulated,ranging from a single continuous bout through to sporadic accumulation spread across the day.Durations(X)considered ranged from 1 to 20 min.The outcome was mortality.Results:In total,94,541 participants(56.5% female)were included.Over a median(interquartile range)follow-up of 6.9(6.3,7.4)years,2649(2.8%)deaths occurred.Intensity moderated the association between how the most active minutes of the day were accumulated and mortality risk,expressed relative to sporadically accumulated moderate PA.If the most active minutes were of moderate intensity,the risk of mortality was halved for continuous compared to sporadic accumulation,irrespective of duration;if the most active minutes were of vigorous intensity,a continuous bout was associated with the lowest risk for durations under 5 min(e.g.,3 min:hazard ratio(HR)=0.27,95% confidence interval(95%CI):0.21-0.34),while sporadic accumulation was associated with the lowest risk for durations beyond 5 min(HR=0.11,95%CI:0.08-0.15 for the most active 20 min).Conclusion:Optimal PA patterns for reducing mortality differ by intensity and duration.For moderate-intensity PA,a lower mortality risk may be optimized by prioritizing continuous PA for up to 20 min.However,for vigorous-intensity PA,multiple short bouts(<5 min)may be optimal.This suggests tailored PA recommendations may enhance longevity benefits.
基金supported by the Ministry of Education of the Republic of Korea and the National Research Foundation of Korea(NRF-2024S1A5A2A01028034).
文摘We examine technology ETF and uncertainty index(VIX,GVZ,and OVZ)spillover dynamics and quantile frequency interconnectedness across market states.This study is the first to use quantile-frequency spillover,quadruple wavelet coherence,and wavelet quantile correlation methodologies to facilitate these analyses.The total connectedness index value is 70%,which is much higher in both the upper and lower quantiles.Under normal market conditions,short-term connectedness significantly exceeds long-term connectedness.Levels of ETF-uncertainty indicator connectedness increase under extreme market conditions;most technology ETFs are net spillover transmitters and uncertainty indices net spillover receivers,indicating the contagion risk of ETF investments.We show that while greater ETF-uncertainty index connectedness may benefit portfolio diversification,large fluctuations in technology EFTs can result in financial instability due to high market volatility.In the long term,the joint effects of uncertainty indices on ETFs are significant,with negative correlations between ETFs and uncertainties at different frequencies,supporting the potential role of uncertainty indices in hedging technology ETF portfolio risks.Dynamic portfolio rebalancing,scenario analysis,and stress testing may help to manage the effects of high connectedness.
基金financially supported by the Natural Science Foundation of Henan(242300421010)National Natural Science Foundation of China(52403055).
文摘As living standards improve,the energy consumption for regulating indoor temperature keeps increasing.Windows,in particular,enhance indoor brightness but also lead to increased energy loss,especially in sunny weather.Developing a product that can maintain indoor brightness while reducing energy consumption is a challenge.We developed a facile,spectrally selective transparent ultrahigh-molecular-weight polyethylene composite film to address this trade-off.It is based on a blend of antimony-doped tin oxide and then spin-coated hydrophobic fumed silica,achieving a high visible light transmittance(>70%)and high shielding rates for ultraviolet(>90%)and near-infrared(>70%).When applied to the acrylic window of containers and placed outside,this film can cause a 10℃ temperature drop compared to a pure polymer film.Moreover,in building energy simulations,the annual energy savings could be between 14.1%~31.9%per year.The development of energy-efficient and eco-friendly transparent films is crucial for reducing energy consumption and promoting sustainability in the window environment.
基金the Research Training Program International(RTPi)scholarship from Commonwealth Australiathe top-up scholarship provided by SureNut Ltd.SureNut Ltd.for supplying all the almonds used in this study.
文摘Aflatoxin B1(AFB1)is a toxic fungal metabolite that contaminates almonds from cultivation to harvesting.It leads to chronic health problems and significant economic loss to the producers.Therefore,a fast and non-invasive detection technique is crucial for safeguarding food safety by swiftly identifying and eliminating contaminated almonds from the supply chain.Hyperspectral imaging has been explored as a potential non-destructive technology for detecting AFB1.However,the diverse geometries of almonds present a significant challenge on acquired images,thereby impacting the accuracy of the developed prediction and classification models.This study investigates the effectiveness of short-wave infrared(SwIR)hyperspectral imaging combined with deep learning for detecting AFB1 in almonds of varying geometries.Initially,partial least squares regression(PLSR)and support vector machine(SvM)regression models were evaluated for quantification,while SVM and quadratic discriminant analysis(QDA)classifiers were applied for classification.The results indicated that spectral responses varied with almond thickness,making quantification models unreliable for industrial applications.The Competitive Adaptive Reweighted Sampling(CARS)algorithm was employed to identify key spectral features for developing multi-spectral AFB1 classification models to evaluate the feasibility of high-speed,accurate in-line detection.The deep learning approach significantly outperformed traditional machine learning models,with the pre-trained Inception V3 network achieving a cross-validation accuracy of 84.82%,an F1-score of 0.8522,and an area under curve of 0.893.These findings highlight the superiority of deep learning-based hyperspectral imaging for accurate and reliable AFB1 detection in almonds with diverse shapes and thicknesses.
基金supported by Australian Research Council(ARC)grant DP16010437 to MH.LJM is supported by an ARC DECRA Fellowship,DE210101126.
文摘The Tasmanian microcontinent,situated along the East Gondwana accretionary margin during the late Neoproterozoic and early Palaeozoic,contains an unequivocal high-pressure metamorphic record comprising key information pertaining to the geodynamics of subduction along the margin.Subduction of the Tasmanian microcontinent is interpreted by some as a response to back-arc basin inversion prior to ophiolite obduction and high-pressure metamorphism during the Cambrian Tyennan Orogeny.However,thermobarometric evidence in support of such a model from rocks once positioned on the subducting continental margin is lacking.Despite occurrences of eclogite-facies mineral assemblages in the strongly deformed Tyennan Region of western Tasmania,garnet-bearing quartzofeldspathic assemblages documented in metasedimentary lithologies from the remote south-west coast of Tasmania have been interpreted as an expression of low-to moderate-pressure metamorphism.We report a strongly overprinted chlorite-quartz-garnet-bearing assemblage from the southern Tyennan Region(Nye Bay)which shows evidence for high-pressure metamorphism.Coarse-grained garnet porphyroblasts contain inclusions of kyanite,muscovite,and rutile,and yield in-situ Lu-Hf dates of c.520 Ma.The cm-scale garnet porphyroblasts are zoned in the major and trace elements,preserving core-rim compositional gradients reflecting garnet growth up-pressure.Aided by mineral equilibria forward modelling,the garnet rim compositions and the Zr content of Cambrian rutile constrain peak metamorphic conditions of∼17.5-19 kbar and∼780-820℃,equivalent to warm subduction thermal gradients between 410-470℃/GPa.Garnet core compositions and the Ti content of quartz inclusions in the garnet cores constrain the pressures and temperatures for garnet nucleation to∼6-7 kbar and∼560-580℃,corresponding to relatively high prograde thermal gradients between 800-965℃/GPa.The thermal gradients determined from the south-west Tasmanian metamorphic record provide a direct window into the progressive evolution of the thermal state of the Cambrian subduction system,with the physical conditions of garnet nucleation potentially reflecting those of subduction initiation.The corresponding warm thermal gradients provide evidence for subduction initiation driven by the collapse of a pre-orogenic back-arc.This interpretation is consistent with an existing tectonic model for the Tyennan Orogeny which proposes a back-arc basin origin for the protoliths to the western Tasmanian sub-ophiolitic metamorphic sole.
基金National Natural Science Foundation of China(No.21876025)National Key R&D Program of China(No.2023YFC3207204)Shanghai Municipal Education Commission Artificial Intelligence-Enabled Scientific Research Plan,China(No.SMEC-AI-DHUZ-07)。
文摘From a quantum chemistry standpoint,the impact of the structural properties of the compounds on activated carbon’s adsorption ability was specifically investigated.The compounds whose adsorption behavior followed the Langmuir isotherm model were selected as the research objects.An optimal quantitative structure-activity relationship(QSAR)model was built by using the multiple linear regression(MLR)method,with the saturation adsorption capacity Q_(m) from the Langmuir adsorption isotherm as the response variable and the structural parameters of 50 organic compounds as independent variables.The results show that the optimal model exhibits good stability,reliability and robustness,with a regression coefficient R^(2)of 0.88,an adjusted regression coefficient R_(adj)^(2) of 0.87,an internal validation coefficient q^(2) of 0.81,and an external validation coefficient Q_(ext)^(2) of 0.68.The variables included in the optimal model indicate that the polarity of the molecule,the molecular potential energy,and the stability and bonding strength of the organic compound are the main factors affecting the adsorption on activated carbon.The results provide key information for predicting the adsorption capacity of organic compounds on activated carbon and offer a theoretical reference for adsorption treatment in water environments.
文摘Device-based measurements are recommended to improve population-based physical activity(PA)surveillance.1,2However,implementation remains challenging due to lack of consensus on analytical methods,and the most widely used“generic”(absolute intensity)cut-point approach has limited generalisability to population-level free-living data.Further,current methods generally fail to account for differences in people's physical capacity.
基金National Natural Science Foundation of China under Grant No.52108473Project of Shaanxi Engineering Technology Research Center for Urban Geology and Underground Space under Grant No.2025KT-03Key Project of Education Department of Shaanxi Province under Grant No.23JY042。
文摘Ground fissure,as a common geo-hazard,impairs the integrity of the site soil and affects the seismic performance of engineering structures.In this paper,a finite element(FE)model for subway stations in a ground fissure area was developed and validated by using experimental results.Numerical analyses were conducted to investigate the seismic response and failure mode of subway stations in a ground fissure area with different locations.Effects of ground fissure on deformations and internal forces of a station,soil pressures and soil plastic strains were discussed.The results showed that the seismic response of the station was significantly amplified by the ground fissure,and stations in the ground fissure area displayed obvious rocking deformation during earthquakes as compared to those in the area without fissures.It also was found that the soil yielding around the station,the dislocation occurring in the ground fissure area,and the dynamic amplification effect were more significant under vertical ground motion,which weakened the station’s ductility and accelerated its destruction process.
基金supported by the National Institute for Health Research (NIHR) Leicester Biomedical Research Centre and NIHR Applied Research Collaboration East Midlands (ARC EM, (IS-BRC-1215-20010))funded by the National Institute for Health and Care Research Bristol Biomedical Research Centre (IS-BRC-1215-20011)supported by a UKRI research grant (EP/X042464/1)。
文摘Background Higher accelerometer-assessed volume and intensity of physical activity(PA)have been associated with a longer life expectancy but can be difficult to translate into recommended doses of PA.We aimed to:(a)improve interpretability by producing UK Biobank age-referenced centiles for PA volume and intensity;(b)inform public-health messaging by examining how adding recommended quantities of moderate and vigorous PA affect PA volume and intensity.Methods 92,480 UK Biobank participants aged 43-80 years with wrist-worn accelerometer data were included.Average acceleration and intensity gradient were derived as proxies for PA volume and intensity.We generated sex-specific centile curves using Generalized Additive Models for Location Scale and Shape(GAMLSS)and modeled the effect of adding moderate(walking)or vigorous(running)activity on the combined change in the volume and intensity centiles(change in PA profile).Results In men,volume was lower as age increased while intensity was lower after age 55;in women,both volume and intensity were lower as age increased.Adding 150 min of moderate PA weekly(5×30 min walking)increased the PA profile by 4 percentage points.Defining moderate PA as brisk walking approximately doubled the increase(9 percentage points)while 75 min of vigorous PA weekly(5×15 min running)trebled the increase(13 percentage points).Conclusion These UK Biobank reference centiles provide a benchmark for interpretation of accelerometer data.Application of our translational methods demonstrate that meeting PA guidelines through shorter duration vigorous activity is more beneficial to the PA profile(volume and intensity)than longer duration moderate activity.
基金supported by a grant from the European Union's Horizon 2020 research and innovation programme under the Marie Sklodowska Curie(Grant agreement No.101028929)supported by an Investigator Grant from the Medical Research Future Fund(MRF1193862)supported by an Australian Government Research Training Program Scholarship.
文摘Background:Cardiorespiratory fitness(CRF)is a powerful health marker recommended by the American Heart Association as a clinical vital sign.Comparing the predictive validity of objectively measured CRF(the"gold standara")and estimated CRF is clinically relevant because estimated CRF is more feasible.Our objective was to meta-analyze cohort studies to compare the associations of objectively measured,exerciseestimated,and non-exercise-estimated CRF with all-cause and cardiovascular disease(CVD)mortality in adults.Methods:Systematic searches were conducted in 9 databases(MEDLINE,SPORTDiscus,Embase,Scopus,PsycINFO,Web of Science,PubMed,CINAHL,and the Cochrane Library)up to April 11,2024.We included full-text refereed cohort studies published in English that quantified the association(using risk estimates with 95%confidence intervals(95%CIs))of objectively measured,exercise-estimated,and non-exercise-estimated CRF with all-cause and CVD mortality in adults.CRF was expressed as metabolic equivalents(METs)of task.Pooled relative risks(RR)for all-cause and CVD mortality per 1-MET(3.5 mL/kg/min)higher level of CRF were quantified using random-effects models.Results:Forty-two studies representing 35 cohorts and 3,813,484 observations(81%male)(362,771 all-cause and 56,471 CVD deaths)were included.The pooled RRs for all-cause and CVD mortality per higher MET were 0.86(95%CI:0.83-0.88)and 0.84(95%CI:0.80-0.87),respectively.For both all-cause and CVD mortality,there were no statistically significant differences in RR per higher MET between objectively measured(RR range:0.86-0.90)and maximal exercise-estimated(RR range:0.85-0.86),submaximal exercise-estimated(RR range:0.91-0.94),and non-exercise-estimated CRF(RR range:0.81-0.85).Conclusion:Objectively measured and estimated CRF showed similar dose-response associations for all-cause and CVD mortality in adults.Estimated CRF could provide a practical and robust alternative to objectively measured CRF for assessing mortality risk across diverse populations.Our findings underscore the health-related benefits of higher CRF and advocate for its integration into clinical practice to enhance risk stratification.
