Synthetic fertilizers are widely used to address the urgent challenge of ensuring food supplies for a growing world population in the context of climate change. However, their industrial production and use in agricult...Synthetic fertilizers are widely used to address the urgent challenge of ensuring food supplies for a growing world population in the context of climate change. However, their industrial production and use in agriculture have a negative impact on the environment and consequently on human health. While chemical fertilizers may not have to be abandoned in agricultural production systems, limiting their use could help to make agriculture sustainable and resilient to climate change. In Senegal, the level of mineral fertilizers used in market gardening has become alarming in the Niayes area. As a result, microbial biotechnologies have been promoted for biofertilizer production of common bean (Phaseolus vulgaris L.) cultivation. Rhizobial inoculums have thus been used to reduce the rate of chemical nitrogen fertilizers being applied in cropping systems. Several investigations in the laboratory, on experimental stations and in the field have shown a possibility of a significant reduction in the use of nitrogen fertilizers in common bean production. Conventional mineral fertilization use can be reduced from over 120 kg N/ha to 20 kg N/ha. This contributes both to a very significant reduction in the application rate with the same level of yield and to an improvement in the standard of living. In addition, the environmental impact of using chemical fertilizers can be mitigated. This study is a contribution to the promotion of biofertilizers adoption in agricultural systems.展开更多
Purpose: The aim of the study was to investigate the profile of psychoactive substance users in Senegal from 2018 to 2022. Methodology: These were retrospective descriptive studies of patient consultation and hospital...Purpose: The aim of the study was to investigate the profile of psychoactive substance users in Senegal from 2018 to 2022. Methodology: These were retrospective descriptive studies of patient consultation and hospitalization records in the 17 psychiatric and addictology care centers in Senegal from 2018 to 2022. This was an exhaustive survey. All usable consultation and hospitalization registers were included in the study. Non-usable consultation and hospitalization registers were not included. Data were collected from January 1 to December 31 of each respective year. Data were cleaned using Excel before analysis. R software version 4.3.3 was used for analysis. Results: Between 2018 and 2022, 26,029 patients were registered in mental health facilities in Senegal. The Fann Psychiatry Department (CHNU Fann) admitted 23.2% of patients and the Thiaroye National Psychiatric Hospital registered 17.6% of drug users. For the year 2019, we found 8259 and in 2021, we had 6607 patients. The male gender was more represented with 14,750 patients, or 90.9%. The age group [25 - 34] was the majority (7013 patients or 39.5%). The majority of patients (17,425 patients, or 84.6%) were followed as outpatients. The drugs were mainly inhaled (96.7%). The most consumed substance was cannabis with 8847 patients, or 54.2%. Withdrawal was the main reason for treatment, 11,614 patients, or 85.7%. Conclusion: In the light of the results of our study, we can say that the use of psychoactive substances is a real public health and development problem in Senegal. The peaks in psychoactive substance consumption preceded the peaks in psychiatric care centers, so we need to promote information, education and communication on the harmful effects of psychoactive substance consumption among the population in general and young people in particular, in order to safeguard the country’s development.展开更多
Introduction: Stroke may have a negative impact on mental health and behavior. Cognitive disorders are common after stroke. They are rarely assessed in current clinical practice, particularly in our context. They cons...Introduction: Stroke may have a negative impact on mental health and behavior. Cognitive disorders are common after stroke. They are rarely assessed in current clinical practice, particularly in our context. They constitute a real “invisible” handicap. In sub-Saharan Africa, we are not aware of any studies specifically assessing executive functions. These functions are at the heart of all adaptation processes to new or complex situations. This prompted the authors to carry out this study at the Ibrahima Pierre Ndiaye Neuroscience Department of the Fann National University Hospital Centre (Senegal). Objective and Methodology: The aim of this study was to assess and characterize post-stroke alterations in executive functions in our context. We conducted a descriptive cross-sectional study. It took place over a 4-month period from April 1 to August 31, 2021. Patients were matched to controls according to age, gender and educational level. Executive functions were assessed using the Frontal Assessment Battery (FAB). Results: A total of 30 patients with stroke were enrolled. These patients were matched to controls. The mean age of the patients was 46.87 ± 17.65 years. For the control group, it was 39.27 ± 12.33 years. The prevalence of executive function disorders was 20% in post-stroke patients. The majority of executive functions assessed were impaired. Sensitivity to interference and environmental autonomy were the only ones preserved. Conclusion: Impaired executive functions are common after stroke. They should be systematically assessed in all stroke patients to ensure optimal management.展开更多
This study evaluated the molecular characterization of different ecotypes of B. aegyptiaca populations in the four sites: Koily alpha, Labgar, Ranérou and Ballou according to the environment with the aim of devel...This study evaluated the molecular characterization of different ecotypes of B. aegyptiaca populations in the four sites: Koily alpha, Labgar, Ranérou and Ballou according to the environment with the aim of developing protection strategies. We sampled leaves of B. aegyptiaca in each individual from each site to extract and amplify a fragment of mitochondrial DNA including cytochrome b and then carefully preserved. DNA extraction, polymerase chain amplification and sequencing of MT-CYB were performed in 64 individuals. Genetic diversity and structure of B. aegyptiaca were determined using the MEGA, DNasp and Arlequin software. The results showed a high haplotype diversity and low nucleotide diversity, indicating a population expansion linked to an important gene flow. Genetic distances between populations were positively correlated with geographic distance. The importance of having highlighted this genetic differentiation of the B. aegyptiaca species between these sites is to be able to understand the degree of genetic heterogeneity of each and correlate it with adaptability because genetic diversity influences the adaptation of the species.展开更多
Introduction: the left atrial appendage, a dormant embryonic vestige, would play a major role in cardiac hemodynamic changes, volume homeostasis and thrombi formation. It, therefore constitutes a therapeutic target. I...Introduction: the left atrial appendage, a dormant embryonic vestige, would play a major role in cardiac hemodynamic changes, volume homeostasis and thrombi formation. It, therefore constitutes a therapeutic target. Its morphology is extremely variable. Objective: it consisted on determining the morphological variations of the left auricle as well as their interest in the prevention of thrombi in the Senegalese. Material and Method: This study was conducted by dissecting 36 fresh hearts from Senegalese anatomical subjects with a sampling of the left atrial appendage, including specimens with normal morphological appearance. Their morphology was studied using the fresh and frozen plaster molding method. The data obtained were analyzed statistically. Results: the average age of the subjects was 33 years, with a sex ratio of 1.06, the cauliflower shape was dominant with 57% of cases and the cactus shape (4%) was less frequent. The cauliflower shape presented a clear angulation compared to the others without statistically significant differences according to age. Conclusion: This work showed a great morphological variability of the left atrial appendage. It can provide an update on the specificity of Senegalese. Taking these variations into account is important in the safe management of hemodynamic conditions and the improvement of the management of recurrent strokes.展开更多
The aim of the present study was to evaluate the effects of baobab seed washing and origin on the chemical composition of the oil extracted by pressing. Six (6) oil samples were obtained from seeds of three (3) geogra...The aim of the present study was to evaluate the effects of baobab seed washing and origin on the chemical composition of the oil extracted by pressing. Six (6) oil samples were obtained from seeds of three (3) geographical origins. The identification and quantification of fatty acids and the polyphenolic profile were carried out by GC-MS and HPLC-UV, respectively. Analysis of fatty acid methyl esters allowed the identification and quantification of 18 fatty acids. Oils from unwashed seeds were richer in palmitic (C16:0), stearic (C18:0), oleic (C18:1) and arachidic (C20:0) acids. In addition, HPLC-UV analysis at 279 nm shows that oils from unwashed seeds are richer in tyrosol, hydroxytyrosol and caffeic acid. With regard to the polyphenolic profile, gallic acid and quercetin were not detected in these baobab oils. Principal component analysis of fatty acid and phenolic compound content showed that oils from unwashed seeds would best preserve their chemical and associated potential bioactive characteristics.展开更多
Until recently,potassium(K)has not received considerable attention because of the general belief that soils contain ample amounts of this element.In addition,low rates of K fertilizer application in agriculture have l...Until recently,potassium(K)has not received considerable attention because of the general belief that soils contain ample amounts of this element.In addition,low rates of K fertilizer application in agriculture have led to rapid depletion of K in the rhizosphere soil in many underdeveloped countries.This results in various negative impacts,including preventing optimum utilization of applied nitrogen and phosphorus fertilizers.To compensate for these losses,massive use of K fertilizers in agriculture has been suggested.Potassium fertilizers are manufactured from rock minerals,particularly sylvite(KCl)and carnallite(KCl·MgCl2·6H2O).Unfortunately,to date,there is no cost-effective technology available for converting rock minerals into potassic fertilizers.Potassium-solubilizing microorganisms(KSMs)can release K from soil/minerals into plant-available forms,which could be a sustainable option.The possibility of using KSMs as efficient biofertilizers to improve crop production has been increasingly highlighted by researchers.In this review,the existing forms of K in soils and their availability and dynamic equilibrium are discussed.In addition,different K fertilizers and their advantages and disadvantages for crops are described.Furthermore,the microorganisms usually reported as K solubilizers,the research progress on KSMs,and future insights on the use of these KSMs in agriculture are reviewed.Screening and analyses of the published literature show that organic acid production is the common mechanism of K solubilization by bacteria and fungi.This review may serve as a proposal for the future research avenues identified here.展开更多
Introduction: Sleep disorders (SD) are common dialysis patients and can impact their quality of life. In previous studies, black ethnicity was associated with higher incidence of SD but a few data are available in Afr...Introduction: Sleep disorders (SD) are common dialysis patients and can impact their quality of life. In previous studies, black ethnicity was associated with higher incidence of SD but a few data are available in African patients. This study aimed to describe prevalence and risk factors of SD among Senegalese dialysis patients. Methods: We performed a cross-sectional study between February 15th and April 30th 2012 including 127 patients (75 males and 52 females) aged 46.8 ± 16.9 (16 - 85 years) and dialysed since >6 months in three dialysis centres. For each patient, we assessed insomnia according to international definition, obstructive sleep apnea syndrome (OSAS) with the Berlin questionnaire, restless leg syndrome (RLS) using abridged version of Cambridge-Hopkins RLS questionnaire, and excessive daytime sleepiness (EDS) with Epworth sleepiness scale. Logistic multivariate regression was used to identify factors associated with different SD. Results: Overall prevalence of SD was 88% comprising: insomnia (64.3%), OSAS (49.1%), RLS (24.1%) and EDS (20.5%). Forty-two patients presented at least two disorders. No difference was noticed in prevalence of SD between genders (p = 0.14). Level of blood pressure were not different across patients with and without SD. Insomnia correlated with anemia, inflammation and EDS. OSAS was associated with age ≥50 years, EDS and neck circumference ≥25 cm. RLS correlated with anemia and EDS. Other parameters such as gender, dialysis vintage, KT/V, obesity, diabetes status and hypoalbuminemia were not associated with the different SD. The majority of patients had not been diagnosed before the survey and none of them was under treatment. Conclusions: Our findings are compatible with high prevalence of sleep disorders reported in other populations. Insomnia and OSAS are the most frequent SD but some patients combined many disorders. Nephrologists should be more aware of these SD in order to detect them early and provide efficient treatment.展开更多
The objective of this study was to develop allometric models for estimating the biomass of Sclerocarya birrea (A.Rich) Hoscht and Boscia senegalensis (Pers.) Lam. ex Poir. The inventory of these ligneous was carried o...The objective of this study was to develop allometric models for estimating the biomass of Sclerocarya birrea (A.Rich) Hoscht and Boscia senegalensis (Pers.) Lam. ex Poir. The inventory of these ligneous was carried out at Widou Thiengoly (North of Senegal). The sample consists of 43 individuals of Boscia senegalensis and 15 individuals of Sclerocarya birrea. The selected individuals were dendrometrically characterized before being cut, compartmentalized (trunk, branches, and twigs) and weighed entirely. Simple regression tests were performed to examine the most explanatory dendrometric parameter (x) for biomass (y) according to two types of models: the linear model (y = ax + b) and the polynomial model of degrees 2 (y = ax<sup>2</sup> + bx + c). The criteria for selection and validity of the models are based firstly on the tests of normality, nullity, heterogeneity and autocorrelation of the residues. The results showed that the most explanatory dendrometric parameter of the biomass was the crown surface for Boscia senegalensis and the 1.30 m diameter for Sclerocarya birrea of all the tests performed, the second-order Polynomial model is the best predictor of above ground biomass for these two species. Thus, the allometric models established to predict the biomass of these two species are: y = 0.0023x<sup>2</sup> + 0.4851x - 0.0519 for Boscia senegalensis and y = 0.35x<sup>2</sup> + 10.35x - 12.90 for S. birrea;with very significant correlation coefficients (R<sup>2</sup>) of 0.85 and 0.94 respectively. These results can be used for a sequestered carbon assessment study and will play a role in monitoring the carbon market in Africa.展开更多
In Senegal, tomato (<i><span style="font-family:Verdana;">Solanum lycopersicum</span></i><span style="font-family:Verdana;"> L.) cultivation is affected by salinity in...In Senegal, tomato (<i><span style="font-family:Verdana;">Solanum lycopersicum</span></i><span style="font-family:Verdana;"> L.) cultivation is affected by salinity in many agro-ecological zones. The selection of salt tolerant varieties would be an alternative solution to enhance the production. Thus, germination and growth are studied under axenic conditions for five varieties of tomato subjected to increasing concentrations of NaCl [0, 35, 70 and 105 mM], and supplemented in an MS/2 medium for 30 days. The results reveal that salt negatively affects the evaluated parameters. The </span><i><span style="font-family:Verdana;">Rodeo</span></i><span style="font-family:Verdana;"> and </span><i><span style="font-family:Verdana;">Lady Nema </span></i><span style="font-family:Verdana;">varieties have the lowest final germination rates (50%) unlike the </span><i><span style="font-family:Verdana;">Mongal</span></i><span style="font-family:Verdana;"> variety (55%). These last two varieties have a decrease of 71.78% and 81.28% in the height of the stem, respectively, in the presence of NaCl at [105 mM] while that of the </span><i><span style="font-family:Verdana;">Rodeo</span></i><span style="font-family:Verdana;"> variety is 70%. The </span><i><span style="font-family:Verdana;">Xewel</span></i><span style="font-family:Verdana;"> variety has the greatest average number of leaves in the presence of [NaCl 35 mM] (4.95 leaves) and [NaCl 70 mM] (4.77 leaves). The </span><i><span style="font-family:Verdana;">Lady Nema</span></i><span style="font-family:Verdana;"> variety records the longest taproot length (2.99 cm) unlike the </span><i><span style="font-family:Verdana;">Rodeo</span></i><span style="font-family:Verdana;"> variety (2.25 cm) at [NaCl 105 mM]. The </span><i><span style="font-family:Verdana;">Ganila</span></i><span style="font-family:Verdana;"> variety reveals the highest number of secondary roots at the concentrations of [0, 35 and 105 mM] of NaCl with, respectively, 44.12, 29.25, and 4.25 roots. The </span><i><span style="font-family:Verdana;">Lady Nema</span></i><span style="font-family:Verdana;"> variety records the highest fresh weight of aerial (0.055 g) and root parts (0.014 g) and the lowest root dry weights (0.0023 g). These results allow to conclude that the </span><i><span style="font-family:Verdana;">Lady Nema </span></i><span style="font-family:Verdana;">and</span><i><span style="font-family:Verdana;"> Mongal</span></i><span style="font-family:Verdana;"> varieties seem more tolerant, </span><i><span style="font-family:Verdana;">Ganila </span></i><span style="font-family:Verdana;">and</span><i><span style="font-family:Verdana;"> Xewel</span></i><span style="font-family:Verdana;"> are moderately tolerant and </span><i><span style="font-family:Verdana;">Rodeo</span></i><span style="font-family:Verdana;"> is more sensitive to the presence of salt.</span>展开更多
Introduction: Diabetes is a public health problem and is exposed to some complications, particularly infectious. The work on this entity remains segmentary in Africa. The objective was to describe the morbi infectious...Introduction: Diabetes is a public health problem and is exposed to some complications, particularly infectious. The work on this entity remains segmentary in Africa. The objective was to describe the morbi infectious mortality of the diabetics at the Medical Clinic II of Abass Ndao Health Center of Dakar. Patients and Methods: This was a cross-sectional, descriptive and analytical study conducted from 01 January 2016 to 31 December 2016. It covered patients with diabetes hospitalized during the study period. Epidemiological data and infectious diseases were evaluated. Results: During the study period, 346 diabetics have respected the inclusion criteria. These were 165 men (47.68%), a sex ratio of 0.91. The mean age was 56.17 years. The age group of [60 - 69 years] accounted for 31.5% and 95.6% of the patients came from the Dakar region. The average age of diabetes was 10.31. Diabetes had been evolving for less than 5 years in 25.15% of patients and inaugural in 11.46%. About 82.36% of our patients had type 2 diabetes. The acute complications of diabetes were ketoacidosis (51.89%), hyperosmolar hyperglycemia (0.58%), and hypoglycemia (1.45%). The mean infections were the skin and soft tissues (54.91%), urogenital infections (16.18%), respiratory infections (14.45%), malaria (3.46), infections of the skin and soft tissues were dominated by the diabetic foot (41.90%). The 125 non-diabetic patients developed 38 infectious pathologies, the main ones being respiratory infections (24.32%), infections of the skin and soft parts (24.32%). HIV infection was observed in 0.28% of diabetics and 8.10% of non-diabetic patients. 93 patients died (15.70%). Fifty-one of them died of infectious diseases (54.8%), 42 non-infectious diseases (45.16%), and subjects aged over 60 years, representing 72.54%. The means of consultation was 30 days. The highest rates of lethality were diabetes (37.41%), acute gastroenteritis (17.64%), and acute pyelonephritis (12.5%). The lethality rates of indeterminate infections and malaria were 10% and 8.33%, respectively. Conclusion: Infection is a significant complication in diabetics not neglectable to diabetes. These discovery patterns call for more early diagnosis and appropriate management to reduce the mortality of diabetics.展开更多
Water contamination by chemical pollutants is increasingly associated with waterborne diseases worldwide. The objective of this study is to assess the chemical health risk associated with drinking water consumption in...Water contamination by chemical pollutants is increasingly associated with waterborne diseases worldwide. The objective of this study is to assess the chemical health risk associated with drinking water consumption in Dakar, Senegal. The methodology adopted in this study is based on the determination of trace metals (Cd, Pb, Fe, Cu and Mn) in human drinking water by flame atomic absorption spectrometry, the estimation of the exposure of populations of the study area on the basis of the quantity of water consumed daily and the determination of the hazard quotient which allows estimating the health risk. The results indicate unacceptable levels of Pb and Cd in the water according to World Health Organization (WHO) guidelines, while the concentrations of Fe, Cu and Mn are below the regulatory values. The hazard quotient (HQ) is in the majority of samples higher than 1 in children and infants for scenario 1 (based on WHO data), reflecting a high risk for this target. In scenario 2 based on consumption data from the populations studied, the HQ is greater than 1 only in heavy consumers. The drinking water consumed by Dakar population presents health risks related to Pb and Cd, particularly for infants, children and heavy consumers, hence the need to strengthen the water treatment system before home consumption.展开更多
Introduction: Lack of dietary diversity is a nutritional problem among poor people in developing countries whose daily diet is usually based on a starch source with one or two additional components. Senegal has food i...Introduction: Lack of dietary diversity is a nutritional problem among poor people in developing countries whose daily diet is usually based on a starch source with one or two additional components. Senegal has food insecure regions such as Kolda and Kedougou despite improved agricultural production. This study aims to investigate the determinants of dietary diversity in the Kolda and Kedougou regions. Methodology: It was a cross-sectional, descriptive and analytic household-level study in two southern regions of Senegal (Kolda and Kedougou) between October and December 2015. This was a three-stage random sample survey. Dietary diversity in women of reproductive age was measured using the Women’s Dietary Diversity Score (WDDS) recommended by Food and Agriculture Organization of the United Nations (FAO). The WDDS is a global qualitative indicator of nutrition, which counts the number of food groups consumed by a person in the 24 hours preceding the survey. The data was collected during an individual interview. Linear regression was used to identify the associated factors of dietary diversity. The free and informed consent of the individuals surveyed and the protection of anonymity were respected. Results: A total of 1926 women were surveyed. The mean of WDDS was 2.9 with a standard deviation of 1.4. The Kedougou department has a better WDDS with 3.3 (±1.2) followed by the Kolda department with a score of 3.2 (±1.3). The higher the household’s welfare score, the better the WDDS with a ßcoefficient of 0.11 [0.09 - 0.13]. Households that are in urban areas have a better score than households in rural areas (0.27 [0.13 - 0.41]). The improvement of knowledge in food diversification, in good culinary practice improves the dietary diversity score in women. Conclusion: The WDDS is low in the southern regions of Senegal. To improve dietary diversification in this area, the practice of good cooking practices, the accessibility of micronutrient-rich foods, and the decision-making power of women in the household should be promoted.展开更多
<strong>Aim:</strong><span><span><span style="font-family:""><span style="font-family:Verdana;"> We endeavored to describe the epidemiological profile of pr...<strong>Aim:</strong><span><span><span style="font-family:""><span style="font-family:Verdana;"> We endeavored to describe the epidemiological profile of prostatic cancer, and to evaluate its diagnostic and therapeutic aspects. </span><b><span style="font-family:Verdana;">Method:</span></b><span style="font-family:Verdana;"> We conducted a descriptive retrospective study on the conformational radiotherapy of prostatic adenocarcinoma at the Dalal Jamm University Hospital, Senegal from June 2018 to December 2019. We included 62 consecutive patients. The average age of the patients was 68.9 years. The average consultation time was 7.6 months. </span><b><span style="font-family:Verdana;">Results:</span></b><span style="font-family:Verdana;"> Symptom manifestation and high PSA triggered the diagnosis of cancer in 74.2% and 25.8% of patients, respectively. Symptoms: pollakiuria (72.3%), bone pain (8%) and erectile dysfunction (4.8%). The digital rectal examination: normal (33.8%), nodular (30.6%), induration (24.1%), and shielding (11.3%). The mean PSA level was 90.6 ng/ml. Histology: adenocarcinoma was the most common (98.6%). The Gleason score: <7 (45.1%), =7 (35.5%), and >7 (19.4%). The majority of patients were in the high-risk group (70.9%) and 7 patients (11.2%) were metastatic at diagnosis. Therapy: first radical prostatectomy (20.9%), first-line curative radiotherapy (67.8%), adjuvant (21%) and palliative radiotherapy in 7 patients (11.2%): patients having received palliative radiotherapy had an estimated decline in symptoms of 80%. Hormone therapy was performed in 88.8% of patients, with average duration of 12.5 months. After a mean follow-up of 15 months, 59 patients were alive, including 45 cases (81.8%) in complete remission;3 patients with metastasis at the first visit (having received palliative ra</span><span><span style="font-family:Verdana;">diotherapy) died. </span><b><span style="font-family:Verdana;">Conclusion:</span></b><span style="font-family:Verdana;"> The collected data show a profile of prostate cancer that is specific to the sub-Saharan context in which the discovery is still late. Also in comparison to developed countries, the therapeutic means</span></span><span style="font-family:Verdana;"> necessary to fight against this cancer are limited, even though three-dimensional conformational radiotherapy remains an effective and essential treatment;this study provided fundamental data in the area of insufficient data/tools.</span></span></span></span>展开更多
The Bangaani area is located in the northwestern part of the Karthala Massif on the island of Grande Comore, about 10 km from the capital Moroni. It is essentially constituted of basalt plateaus outcropping in the for...The Bangaani area is located in the northwestern part of the Karthala Massif on the island of Grande Comore, about 10 km from the capital Moroni. It is essentially constituted of basalt plateaus outcropping in the form of pahoehoe and aa lava flows or in the form of massive vesicular or non vesicular basalt flows. Petrographic analysis of the massive basalts studied shows a porphyritic microlitic texture marked by the successive crystallization of olivines, opaque minerals, clinopyroxenes and plagioclases in a relatively abundant mesostasis. This crystallization sequence is typical of a high pressure environment corresponding to primary alkaline magmas. The geochemical study of major and trace elements shows that the basalts studied are under saturated in silica (47.24%) but rich in alkali (2.26%) and titanium (2.66%). They correspond to intraplate alkaline basalts of type oceanic island basalts (OIB) and present a primary character marked by relatively high contents of magnesium (6.69%), chromium (151.23 ppm), nickel (107.53 ppm) and scandium (27.15 ppm). The REE and multi-element diagrams confirm that the Karthala basalts are alkaline basalts of type OIB by their enrichment in LILE and their depleted character in HREE and HFSE. In terms of isotopic ratios, they are comparable to HIMU and EM I.展开更多
Introduction: Chronic respiratory diseases (CRD) are obvious effects of air pollution and the third reason of death in developing countries. In Africa, air pollution from road traffic is one of the main causes of poor...Introduction: Chronic respiratory diseases (CRD) are obvious effects of air pollution and the third reason of death in developing countries. In Africa, air pollution from road traffic is one of the main causes of poor air quality. We set out to systematically review existing published researches on traffic related to air pollution and CRD, particularly asthma and Chronic Obstructive Pulmonary Disease (COPD) in Africa. Methods: A literature search of PubMed, Scholar and LISSA databases, published journals, reference articles, published up to 31 December 2016, has been done by using a research strategy procedure. Texts were reviewed for inclusion. Studies were included if they met the following criteria: 1) the relationship between asthma or COPD with ambient air pollution related to road traffic was studied and 2) the population included people from Africa or lived in Africa. Articles written in English and French were included. Results: Fifty-five articles were selected in this review, of which twenty-seven were on air pollution and CRD in Africa. The proximity of the residence or workplace to the traffic is associated with an increased risk of asthma with a dose-response relationship. The estimated prevalence of COPD varies between 2.7% and 38.5%. Conclusion: There is little research on traffic related to air pollution and CRD in Africa. Strategies to reduce traffic related to air pollution in African cities have been proposed in order to have a healthier ambient air.展开更多
The Sahelian regions have experienced a drought that has made them vulnerable to hydro-climatic conditions. Strategies have been developed to re</span><span style="font-family:Verdana;">duce this...The Sahelian regions have experienced a drought that has made them vulnerable to hydro-climatic conditions. Strategies have been developed to re</span><span style="font-family:Verdana;">duce this vulnerability. The governments of Senegal, Mauritania, Mali and Guinea</span><span style="font-family:Verdana;"> have created the Organization for the development of the Senegal River (OMVS in french) with the aim of realizing large hydraulic installations. This resulted in the construction of the Diama and Manantali dams in the Senegal River Basin. The first aims to stop the saline intrusion, the second to regulate the flow of the river, to allow the irrigation of agricultural perimeters, and to produce electrical energy. The impoundment of the Diama dam has modified the hydraulic behavior of the estuary. The purpose of this study is to carry out </span><span style="font-family:Verdana;">the hydraulic modeling of the estuary of Senegal river downstream of the Diama Dam in transient mode by the HEC-RAS software. Two geometric models were </span><span style="font-family:Verdana;">constructed on the basis of a digital terrain model (DTM) using the Arc-GIS and HEC GeoRAS soft wares after processing the collected topographic data. The first geometric model, of which the areas of Senegal river downstream Diama Dam have been represented by cross-section, is one-dimensional. The </span><span style="font-family:Verdana;">second one is also one dimensional;in this model, the area of the Senegal River </span><span style="font-family:Verdana;">estuary downstream Diama Dam is introduced as water storage zones. The components of these models are the stream sections, lateral links, and storage areas. The flood hydrograph downstream Diama Dam is introduced as conditions at the upstream limits of the models while the tidal is introduced as a downstream condition. After the stability and calibration, the results given by HEC-RAS simulations are the variations of the water levels, the temporal variations of the flow rates for each section, the maximum flow velocities and the propagation times of the flood waves. The analysis and comparisons of these results strongly suggest using HEC-RAS issues as a decision-making tool helping to manage floods during times of crisis.展开更多
Bioactive compounds in plants are associated with the reduction of chronic diseases. The free radical scavenging activity of different extracts of a medicinal plant, </span></span><span style="font...Bioactive compounds in plants are associated with the reduction of chronic diseases. The free radical scavenging activity of different extracts of a medicinal plant, </span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"><i></span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><i><span style="font-family:Verdana;">Sclerocarya</span></i></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"> <i>birrea</i></span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><i><span style="font-family:Verdana;"></i></span></i></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">, has been investigated using the DPPH test, ABTS test and FRAP. Three extracts were prepared from the leaves and bark: hydro-methanolic, hydro-acetonic and aqueous. Phytochemical screening was carried out the standard methods followed by the determination of the polyphenol by Folin-Ciocalteu method. The analysis of variance (ANOVA) with the STATISTICA 7.1 and statistical significance was set at p </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"><</span></span></span><span><span><span style="font-family:""><span style="font-family:Verdana;"> 0.05. Evolution of percent inhibition (PI) as well as the IC</span><sub><span style="font-family:Verdana;">50</span></sub><span style="font-family:Verdana;"> of the extracts w</span></span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">as</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"> obtained using the Origin Pro 8.5 software and Microsoft Excel. The results show that the bark extracts are about twice as rich in polyphenols as the leaves. With DPPH at 1.25 mg/mL, the bark has a PI of 91.04% ± 0.001% while leaves, reach 99.80% ± 0.021%. As for the ABTS test, the bark extract reached its maximum activity at 1.25 mg/m</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">L</span></span></span><span><span><span style="font-family:""><span style="font-family:Verdana;"> with a PI of 99.80% ± 0.003% while leaves extract greater value of PI is 99.75 ± 0.003 at 2.5 mg/mL. With FRAP test at 1.25 mg/mL, the bark has a PI of 79.29% ± 0.005% while leaves, reach 80.33% ± 0.001%. The IC</span><sub><span style="font-family:Verdana;">50</span></sub><span style="font-family:Verdana;"> of the bark and leaf extracts on the smallest DPPH are 0.156 ± 0.001 mg/mL in hydro-methanol, 0.301 ± 0.00 mg/mL in hydro-acetone and 0.407 ± 0.00 mg/mL in aqueous extract. With ABTS test, the best IC</span><sub><span style="font-family:Verdana;">50</span></sub><span style="font-family:Verdana;"> are obtained with hydro-acetone extracts with value of 0.247 ± 0.001 </span><span style="font-family:Verdana;">mg/mL for bark and 0.248 ± 0.0005 mg/mL for leaves while in hydro-methanolic</span><span style="font-family:Verdana;"> and aqueous extracts the best IC</span><sub><span style="font-family:Verdana;">50</span></sub><span style="font-family:Verdana;"> are respectively 0.255 ± 0.00 mg/mL and 0.463 ± 0.00 mg/mL. Using ascorbic acid as our standard, the PI was 94.86% ± 0.008% with an IC</span><sub><span style="font-family:Verdana;">50</span></sub><span style="font-family:Verdana;"> of 0.213 ± 0.00 mg/mL. According to these results, the reducing power of the bark is slightly higher than that of the leaves. We can say that the bark has better activity than the leaves and the alcoholic extracts have given better results than the aqueous extract.展开更多
Introduction: To describe the epidemiologic profile, clinical and paraclinical of diabetics presenting microalbuminuria at Marc Sankale center. Patients and methods: We have done cross-sectional and retrospective stud...Introduction: To describe the epidemiologic profile, clinical and paraclinical of diabetics presenting microalbuminuria at Marc Sankale center. Patients and methods: We have done cross-sectional and retrospective study in a descriptive and analytic view or way. It happened within 6 months. Diabetic patients who performed the nycthemeral urinary albumin dose and mentioned in the file were included. The last study is considered as a positive one from 30 to 299mg/24h: Microalbuminuria. The creatinine has been noted and the clearing of the creatinine is calculated through the formula of Cockcroft and Gault. The statistical analysis of data has been done thanks to software such as excel 2013 and SPSS VER 18.0. Results: 221 patients have been noted with 70% women and 30% men. The age varied between 30 years and 85 years with an average of 56, 62 against 9.97 years. Sixty three (63) patients have microalbuminuria (29%);creatinine has been regularized to 25 patients with 14.8% of cases. Among the microalbuminuria patients having completed the creatinine, 32 patients (42.7%) and 16 (21.3%) are respectively in a state of chronical renal failure, light and moderated. Conclusion: The microalbuminuria is frequent to diabetics. But in our series a starting renal insufficiency could precede that microalbuminuria.展开更多
Water is the main limiting factor in the cultivation of tomato (<i>Solanum lyco<span>persicum</span></i><span> L.) in Senegal. Thus, the selection of varieties tolerant to water st</sp...Water is the main limiting factor in the cultivation of tomato (<i>Solanum lyco<span>persicum</span></i><span> L.) in Senegal. Thus, the selection of varieties tolerant to water st</span>ress would be an alternative solution for their production. <i>In vitro </i>germination, growth, total chlorophyll and proline levels were studied in five varieties of tomato subjected to increasing osmotic pressures (0, 5, 10 and 15 kPa) thanks to the PEG-8000 incorporated in an MS/2 medium for 30 days. A strong sen<span>sitivity to water stress for <i>in vitro</i> seed germination in the <i>Rodeo</i> variety (4</span>1%) is recorded at 5 kPa and maintained at 15 kPa (20.83%) while it was only noticed at 15 kPa in the other tomato varieties. The <i>Xewel</i> and <i>Lady Nema</i> varieties obtained the smallest reductions in the number of leaves of vitroplants, with 30.79% and 27.97% at 15 kPa, respectively, and the <i>Rodeo</i> variety recorded a reduction of 35.97%. From 5 kPa, the varieties record reductions in <span>the number of secondary roots of more than 15%. The effect of osmotic pr</span>essures on decreasing the taproot height and length is not significant. The <i>Xewel </i>variety had the highest average fresh (0.483 g) and dry (0.082 g) weights of the aerial part at 15 kPa and the <i>Rodeo</i> variety </span><span style="font-family:"">had </span><span style="font-family:"">the lowest ones (0.308 g and 0.0501 g). The <i>Lady Nema</i> variety had the highest average fresh (0.171 g) and dry (0.039 g) root weights and the <i>Rodeo</i> variety</span><span style="font-family:""> had</span><span style="font-family:""> the lowest ones (0.086 and 0.020 g). The vitroplants of <i>Rodeo </i>variety recorded the highest decreases in total chlorophyll contents at all osmotic pressures and the lowest increase in proline content (53.37%) at 15 kPa. <i>A contrario</i>, the <i>Xewel</i> variety recorded the greatest increase in proline content (116.26%). Ultimately, the vitroplants of <i>Lady Nem</i>a and <i>Xewe</i>l varieties were more tolerant to water stress, the <i>Ganila </i>and<i> Mongal </i>varieties were moderately tolerant and the <i>Rodeo</i> variety was the most sensitive.展开更多
文摘Synthetic fertilizers are widely used to address the urgent challenge of ensuring food supplies for a growing world population in the context of climate change. However, their industrial production and use in agriculture have a negative impact on the environment and consequently on human health. While chemical fertilizers may not have to be abandoned in agricultural production systems, limiting their use could help to make agriculture sustainable and resilient to climate change. In Senegal, the level of mineral fertilizers used in market gardening has become alarming in the Niayes area. As a result, microbial biotechnologies have been promoted for biofertilizer production of common bean (Phaseolus vulgaris L.) cultivation. Rhizobial inoculums have thus been used to reduce the rate of chemical nitrogen fertilizers being applied in cropping systems. Several investigations in the laboratory, on experimental stations and in the field have shown a possibility of a significant reduction in the use of nitrogen fertilizers in common bean production. Conventional mineral fertilization use can be reduced from over 120 kg N/ha to 20 kg N/ha. This contributes both to a very significant reduction in the application rate with the same level of yield and to an improvement in the standard of living. In addition, the environmental impact of using chemical fertilizers can be mitigated. This study is a contribution to the promotion of biofertilizers adoption in agricultural systems.
文摘Purpose: The aim of the study was to investigate the profile of psychoactive substance users in Senegal from 2018 to 2022. Methodology: These were retrospective descriptive studies of patient consultation and hospitalization records in the 17 psychiatric and addictology care centers in Senegal from 2018 to 2022. This was an exhaustive survey. All usable consultation and hospitalization registers were included in the study. Non-usable consultation and hospitalization registers were not included. Data were collected from January 1 to December 31 of each respective year. Data were cleaned using Excel before analysis. R software version 4.3.3 was used for analysis. Results: Between 2018 and 2022, 26,029 patients were registered in mental health facilities in Senegal. The Fann Psychiatry Department (CHNU Fann) admitted 23.2% of patients and the Thiaroye National Psychiatric Hospital registered 17.6% of drug users. For the year 2019, we found 8259 and in 2021, we had 6607 patients. The male gender was more represented with 14,750 patients, or 90.9%. The age group [25 - 34] was the majority (7013 patients or 39.5%). The majority of patients (17,425 patients, or 84.6%) were followed as outpatients. The drugs were mainly inhaled (96.7%). The most consumed substance was cannabis with 8847 patients, or 54.2%. Withdrawal was the main reason for treatment, 11,614 patients, or 85.7%. Conclusion: In the light of the results of our study, we can say that the use of psychoactive substances is a real public health and development problem in Senegal. The peaks in psychoactive substance consumption preceded the peaks in psychiatric care centers, so we need to promote information, education and communication on the harmful effects of psychoactive substance consumption among the population in general and young people in particular, in order to safeguard the country’s development.
文摘Introduction: Stroke may have a negative impact on mental health and behavior. Cognitive disorders are common after stroke. They are rarely assessed in current clinical practice, particularly in our context. They constitute a real “invisible” handicap. In sub-Saharan Africa, we are not aware of any studies specifically assessing executive functions. These functions are at the heart of all adaptation processes to new or complex situations. This prompted the authors to carry out this study at the Ibrahima Pierre Ndiaye Neuroscience Department of the Fann National University Hospital Centre (Senegal). Objective and Methodology: The aim of this study was to assess and characterize post-stroke alterations in executive functions in our context. We conducted a descriptive cross-sectional study. It took place over a 4-month period from April 1 to August 31, 2021. Patients were matched to controls according to age, gender and educational level. Executive functions were assessed using the Frontal Assessment Battery (FAB). Results: A total of 30 patients with stroke were enrolled. These patients were matched to controls. The mean age of the patients was 46.87 ± 17.65 years. For the control group, it was 39.27 ± 12.33 years. The prevalence of executive function disorders was 20% in post-stroke patients. The majority of executive functions assessed were impaired. Sensitivity to interference and environmental autonomy were the only ones preserved. Conclusion: Impaired executive functions are common after stroke. They should be systematically assessed in all stroke patients to ensure optimal management.
文摘This study evaluated the molecular characterization of different ecotypes of B. aegyptiaca populations in the four sites: Koily alpha, Labgar, Ranérou and Ballou according to the environment with the aim of developing protection strategies. We sampled leaves of B. aegyptiaca in each individual from each site to extract and amplify a fragment of mitochondrial DNA including cytochrome b and then carefully preserved. DNA extraction, polymerase chain amplification and sequencing of MT-CYB were performed in 64 individuals. Genetic diversity and structure of B. aegyptiaca were determined using the MEGA, DNasp and Arlequin software. The results showed a high haplotype diversity and low nucleotide diversity, indicating a population expansion linked to an important gene flow. Genetic distances between populations were positively correlated with geographic distance. The importance of having highlighted this genetic differentiation of the B. aegyptiaca species between these sites is to be able to understand the degree of genetic heterogeneity of each and correlate it with adaptability because genetic diversity influences the adaptation of the species.
文摘Introduction: the left atrial appendage, a dormant embryonic vestige, would play a major role in cardiac hemodynamic changes, volume homeostasis and thrombi formation. It, therefore constitutes a therapeutic target. Its morphology is extremely variable. Objective: it consisted on determining the morphological variations of the left auricle as well as their interest in the prevention of thrombi in the Senegalese. Material and Method: This study was conducted by dissecting 36 fresh hearts from Senegalese anatomical subjects with a sampling of the left atrial appendage, including specimens with normal morphological appearance. Their morphology was studied using the fresh and frozen plaster molding method. The data obtained were analyzed statistically. Results: the average age of the subjects was 33 years, with a sex ratio of 1.06, the cauliflower shape was dominant with 57% of cases and the cactus shape (4%) was less frequent. The cauliflower shape presented a clear angulation compared to the others without statistically significant differences according to age. Conclusion: This work showed a great morphological variability of the left atrial appendage. It can provide an update on the specificity of Senegalese. Taking these variations into account is important in the safe management of hemodynamic conditions and the improvement of the management of recurrent strokes.
文摘The aim of the present study was to evaluate the effects of baobab seed washing and origin on the chemical composition of the oil extracted by pressing. Six (6) oil samples were obtained from seeds of three (3) geographical origins. The identification and quantification of fatty acids and the polyphenolic profile were carried out by GC-MS and HPLC-UV, respectively. Analysis of fatty acid methyl esters allowed the identification and quantification of 18 fatty acids. Oils from unwashed seeds were richer in palmitic (C16:0), stearic (C18:0), oleic (C18:1) and arachidic (C20:0) acids. In addition, HPLC-UV analysis at 279 nm shows that oils from unwashed seeds are richer in tyrosol, hydroxytyrosol and caffeic acid. With regard to the polyphenolic profile, gallic acid and quercetin were not detected in these baobab oils. Principal component analysis of fatty acid and phenolic compound content showed that oils from unwashed seeds would best preserve their chemical and associated potential bioactive characteristics.
文摘Until recently,potassium(K)has not received considerable attention because of the general belief that soils contain ample amounts of this element.In addition,low rates of K fertilizer application in agriculture have led to rapid depletion of K in the rhizosphere soil in many underdeveloped countries.This results in various negative impacts,including preventing optimum utilization of applied nitrogen and phosphorus fertilizers.To compensate for these losses,massive use of K fertilizers in agriculture has been suggested.Potassium fertilizers are manufactured from rock minerals,particularly sylvite(KCl)and carnallite(KCl·MgCl2·6H2O).Unfortunately,to date,there is no cost-effective technology available for converting rock minerals into potassic fertilizers.Potassium-solubilizing microorganisms(KSMs)can release K from soil/minerals into plant-available forms,which could be a sustainable option.The possibility of using KSMs as efficient biofertilizers to improve crop production has been increasingly highlighted by researchers.In this review,the existing forms of K in soils and their availability and dynamic equilibrium are discussed.In addition,different K fertilizers and their advantages and disadvantages for crops are described.Furthermore,the microorganisms usually reported as K solubilizers,the research progress on KSMs,and future insights on the use of these KSMs in agriculture are reviewed.Screening and analyses of the published literature show that organic acid production is the common mechanism of K solubilization by bacteria and fungi.This review may serve as a proposal for the future research avenues identified here.
文摘Introduction: Sleep disorders (SD) are common dialysis patients and can impact their quality of life. In previous studies, black ethnicity was associated with higher incidence of SD but a few data are available in African patients. This study aimed to describe prevalence and risk factors of SD among Senegalese dialysis patients. Methods: We performed a cross-sectional study between February 15th and April 30th 2012 including 127 patients (75 males and 52 females) aged 46.8 ± 16.9 (16 - 85 years) and dialysed since >6 months in three dialysis centres. For each patient, we assessed insomnia according to international definition, obstructive sleep apnea syndrome (OSAS) with the Berlin questionnaire, restless leg syndrome (RLS) using abridged version of Cambridge-Hopkins RLS questionnaire, and excessive daytime sleepiness (EDS) with Epworth sleepiness scale. Logistic multivariate regression was used to identify factors associated with different SD. Results: Overall prevalence of SD was 88% comprising: insomnia (64.3%), OSAS (49.1%), RLS (24.1%) and EDS (20.5%). Forty-two patients presented at least two disorders. No difference was noticed in prevalence of SD between genders (p = 0.14). Level of blood pressure were not different across patients with and without SD. Insomnia correlated with anemia, inflammation and EDS. OSAS was associated with age ≥50 years, EDS and neck circumference ≥25 cm. RLS correlated with anemia and EDS. Other parameters such as gender, dialysis vintage, KT/V, obesity, diabetes status and hypoalbuminemia were not associated with the different SD. The majority of patients had not been diagnosed before the survey and none of them was under treatment. Conclusions: Our findings are compatible with high prevalence of sleep disorders reported in other populations. Insomnia and OSAS are the most frequent SD but some patients combined many disorders. Nephrologists should be more aware of these SD in order to detect them early and provide efficient treatment.
文摘The objective of this study was to develop allometric models for estimating the biomass of Sclerocarya birrea (A.Rich) Hoscht and Boscia senegalensis (Pers.) Lam. ex Poir. The inventory of these ligneous was carried out at Widou Thiengoly (North of Senegal). The sample consists of 43 individuals of Boscia senegalensis and 15 individuals of Sclerocarya birrea. The selected individuals were dendrometrically characterized before being cut, compartmentalized (trunk, branches, and twigs) and weighed entirely. Simple regression tests were performed to examine the most explanatory dendrometric parameter (x) for biomass (y) according to two types of models: the linear model (y = ax + b) and the polynomial model of degrees 2 (y = ax<sup>2</sup> + bx + c). The criteria for selection and validity of the models are based firstly on the tests of normality, nullity, heterogeneity and autocorrelation of the residues. The results showed that the most explanatory dendrometric parameter of the biomass was the crown surface for Boscia senegalensis and the 1.30 m diameter for Sclerocarya birrea of all the tests performed, the second-order Polynomial model is the best predictor of above ground biomass for these two species. Thus, the allometric models established to predict the biomass of these two species are: y = 0.0023x<sup>2</sup> + 0.4851x - 0.0519 for Boscia senegalensis and y = 0.35x<sup>2</sup> + 10.35x - 12.90 for S. birrea;with very significant correlation coefficients (R<sup>2</sup>) of 0.85 and 0.94 respectively. These results can be used for a sequestered carbon assessment study and will play a role in monitoring the carbon market in Africa.
文摘In Senegal, tomato (<i><span style="font-family:Verdana;">Solanum lycopersicum</span></i><span style="font-family:Verdana;"> L.) cultivation is affected by salinity in many agro-ecological zones. The selection of salt tolerant varieties would be an alternative solution to enhance the production. Thus, germination and growth are studied under axenic conditions for five varieties of tomato subjected to increasing concentrations of NaCl [0, 35, 70 and 105 mM], and supplemented in an MS/2 medium for 30 days. The results reveal that salt negatively affects the evaluated parameters. The </span><i><span style="font-family:Verdana;">Rodeo</span></i><span style="font-family:Verdana;"> and </span><i><span style="font-family:Verdana;">Lady Nema </span></i><span style="font-family:Verdana;">varieties have the lowest final germination rates (50%) unlike the </span><i><span style="font-family:Verdana;">Mongal</span></i><span style="font-family:Verdana;"> variety (55%). These last two varieties have a decrease of 71.78% and 81.28% in the height of the stem, respectively, in the presence of NaCl at [105 mM] while that of the </span><i><span style="font-family:Verdana;">Rodeo</span></i><span style="font-family:Verdana;"> variety is 70%. The </span><i><span style="font-family:Verdana;">Xewel</span></i><span style="font-family:Verdana;"> variety has the greatest average number of leaves in the presence of [NaCl 35 mM] (4.95 leaves) and [NaCl 70 mM] (4.77 leaves). The </span><i><span style="font-family:Verdana;">Lady Nema</span></i><span style="font-family:Verdana;"> variety records the longest taproot length (2.99 cm) unlike the </span><i><span style="font-family:Verdana;">Rodeo</span></i><span style="font-family:Verdana;"> variety (2.25 cm) at [NaCl 105 mM]. The </span><i><span style="font-family:Verdana;">Ganila</span></i><span style="font-family:Verdana;"> variety reveals the highest number of secondary roots at the concentrations of [0, 35 and 105 mM] of NaCl with, respectively, 44.12, 29.25, and 4.25 roots. The </span><i><span style="font-family:Verdana;">Lady Nema</span></i><span style="font-family:Verdana;"> variety records the highest fresh weight of aerial (0.055 g) and root parts (0.014 g) and the lowest root dry weights (0.0023 g). These results allow to conclude that the </span><i><span style="font-family:Verdana;">Lady Nema </span></i><span style="font-family:Verdana;">and</span><i><span style="font-family:Verdana;"> Mongal</span></i><span style="font-family:Verdana;"> varieties seem more tolerant, </span><i><span style="font-family:Verdana;">Ganila </span></i><span style="font-family:Verdana;">and</span><i><span style="font-family:Verdana;"> Xewel</span></i><span style="font-family:Verdana;"> are moderately tolerant and </span><i><span style="font-family:Verdana;">Rodeo</span></i><span style="font-family:Verdana;"> is more sensitive to the presence of salt.</span>
文摘Introduction: Diabetes is a public health problem and is exposed to some complications, particularly infectious. The work on this entity remains segmentary in Africa. The objective was to describe the morbi infectious mortality of the diabetics at the Medical Clinic II of Abass Ndao Health Center of Dakar. Patients and Methods: This was a cross-sectional, descriptive and analytical study conducted from 01 January 2016 to 31 December 2016. It covered patients with diabetes hospitalized during the study period. Epidemiological data and infectious diseases were evaluated. Results: During the study period, 346 diabetics have respected the inclusion criteria. These were 165 men (47.68%), a sex ratio of 0.91. The mean age was 56.17 years. The age group of [60 - 69 years] accounted for 31.5% and 95.6% of the patients came from the Dakar region. The average age of diabetes was 10.31. Diabetes had been evolving for less than 5 years in 25.15% of patients and inaugural in 11.46%. About 82.36% of our patients had type 2 diabetes. The acute complications of diabetes were ketoacidosis (51.89%), hyperosmolar hyperglycemia (0.58%), and hypoglycemia (1.45%). The mean infections were the skin and soft tissues (54.91%), urogenital infections (16.18%), respiratory infections (14.45%), malaria (3.46), infections of the skin and soft tissues were dominated by the diabetic foot (41.90%). The 125 non-diabetic patients developed 38 infectious pathologies, the main ones being respiratory infections (24.32%), infections of the skin and soft parts (24.32%). HIV infection was observed in 0.28% of diabetics and 8.10% of non-diabetic patients. 93 patients died (15.70%). Fifty-one of them died of infectious diseases (54.8%), 42 non-infectious diseases (45.16%), and subjects aged over 60 years, representing 72.54%. The means of consultation was 30 days. The highest rates of lethality were diabetes (37.41%), acute gastroenteritis (17.64%), and acute pyelonephritis (12.5%). The lethality rates of indeterminate infections and malaria were 10% and 8.33%, respectively. Conclusion: Infection is a significant complication in diabetics not neglectable to diabetes. These discovery patterns call for more early diagnosis and appropriate management to reduce the mortality of diabetics.
文摘Water contamination by chemical pollutants is increasingly associated with waterborne diseases worldwide. The objective of this study is to assess the chemical health risk associated with drinking water consumption in Dakar, Senegal. The methodology adopted in this study is based on the determination of trace metals (Cd, Pb, Fe, Cu and Mn) in human drinking water by flame atomic absorption spectrometry, the estimation of the exposure of populations of the study area on the basis of the quantity of water consumed daily and the determination of the hazard quotient which allows estimating the health risk. The results indicate unacceptable levels of Pb and Cd in the water according to World Health Organization (WHO) guidelines, while the concentrations of Fe, Cu and Mn are below the regulatory values. The hazard quotient (HQ) is in the majority of samples higher than 1 in children and infants for scenario 1 (based on WHO data), reflecting a high risk for this target. In scenario 2 based on consumption data from the populations studied, the HQ is greater than 1 only in heavy consumers. The drinking water consumed by Dakar population presents health risks related to Pb and Cd, particularly for infants, children and heavy consumers, hence the need to strengthen the water treatment system before home consumption.
文摘Introduction: Lack of dietary diversity is a nutritional problem among poor people in developing countries whose daily diet is usually based on a starch source with one or two additional components. Senegal has food insecure regions such as Kolda and Kedougou despite improved agricultural production. This study aims to investigate the determinants of dietary diversity in the Kolda and Kedougou regions. Methodology: It was a cross-sectional, descriptive and analytic household-level study in two southern regions of Senegal (Kolda and Kedougou) between October and December 2015. This was a three-stage random sample survey. Dietary diversity in women of reproductive age was measured using the Women’s Dietary Diversity Score (WDDS) recommended by Food and Agriculture Organization of the United Nations (FAO). The WDDS is a global qualitative indicator of nutrition, which counts the number of food groups consumed by a person in the 24 hours preceding the survey. The data was collected during an individual interview. Linear regression was used to identify the associated factors of dietary diversity. The free and informed consent of the individuals surveyed and the protection of anonymity were respected. Results: A total of 1926 women were surveyed. The mean of WDDS was 2.9 with a standard deviation of 1.4. The Kedougou department has a better WDDS with 3.3 (±1.2) followed by the Kolda department with a score of 3.2 (±1.3). The higher the household’s welfare score, the better the WDDS with a ßcoefficient of 0.11 [0.09 - 0.13]. Households that are in urban areas have a better score than households in rural areas (0.27 [0.13 - 0.41]). The improvement of knowledge in food diversification, in good culinary practice improves the dietary diversity score in women. Conclusion: The WDDS is low in the southern regions of Senegal. To improve dietary diversification in this area, the practice of good cooking practices, the accessibility of micronutrient-rich foods, and the decision-making power of women in the household should be promoted.
文摘<strong>Aim:</strong><span><span><span style="font-family:""><span style="font-family:Verdana;"> We endeavored to describe the epidemiological profile of prostatic cancer, and to evaluate its diagnostic and therapeutic aspects. </span><b><span style="font-family:Verdana;">Method:</span></b><span style="font-family:Verdana;"> We conducted a descriptive retrospective study on the conformational radiotherapy of prostatic adenocarcinoma at the Dalal Jamm University Hospital, Senegal from June 2018 to December 2019. We included 62 consecutive patients. The average age of the patients was 68.9 years. The average consultation time was 7.6 months. </span><b><span style="font-family:Verdana;">Results:</span></b><span style="font-family:Verdana;"> Symptom manifestation and high PSA triggered the diagnosis of cancer in 74.2% and 25.8% of patients, respectively. Symptoms: pollakiuria (72.3%), bone pain (8%) and erectile dysfunction (4.8%). The digital rectal examination: normal (33.8%), nodular (30.6%), induration (24.1%), and shielding (11.3%). The mean PSA level was 90.6 ng/ml. Histology: adenocarcinoma was the most common (98.6%). The Gleason score: <7 (45.1%), =7 (35.5%), and >7 (19.4%). The majority of patients were in the high-risk group (70.9%) and 7 patients (11.2%) were metastatic at diagnosis. Therapy: first radical prostatectomy (20.9%), first-line curative radiotherapy (67.8%), adjuvant (21%) and palliative radiotherapy in 7 patients (11.2%): patients having received palliative radiotherapy had an estimated decline in symptoms of 80%. Hormone therapy was performed in 88.8% of patients, with average duration of 12.5 months. After a mean follow-up of 15 months, 59 patients were alive, including 45 cases (81.8%) in complete remission;3 patients with metastasis at the first visit (having received palliative ra</span><span><span style="font-family:Verdana;">diotherapy) died. </span><b><span style="font-family:Verdana;">Conclusion:</span></b><span style="font-family:Verdana;"> The collected data show a profile of prostate cancer that is specific to the sub-Saharan context in which the discovery is still late. Also in comparison to developed countries, the therapeutic means</span></span><span style="font-family:Verdana;"> necessary to fight against this cancer are limited, even though three-dimensional conformational radiotherapy remains an effective and essential treatment;this study provided fundamental data in the area of insufficient data/tools.</span></span></span></span>
文摘The Bangaani area is located in the northwestern part of the Karthala Massif on the island of Grande Comore, about 10 km from the capital Moroni. It is essentially constituted of basalt plateaus outcropping in the form of pahoehoe and aa lava flows or in the form of massive vesicular or non vesicular basalt flows. Petrographic analysis of the massive basalts studied shows a porphyritic microlitic texture marked by the successive crystallization of olivines, opaque minerals, clinopyroxenes and plagioclases in a relatively abundant mesostasis. This crystallization sequence is typical of a high pressure environment corresponding to primary alkaline magmas. The geochemical study of major and trace elements shows that the basalts studied are under saturated in silica (47.24%) but rich in alkali (2.26%) and titanium (2.66%). They correspond to intraplate alkaline basalts of type oceanic island basalts (OIB) and present a primary character marked by relatively high contents of magnesium (6.69%), chromium (151.23 ppm), nickel (107.53 ppm) and scandium (27.15 ppm). The REE and multi-element diagrams confirm that the Karthala basalts are alkaline basalts of type OIB by their enrichment in LILE and their depleted character in HREE and HFSE. In terms of isotopic ratios, they are comparable to HIMU and EM I.
文摘Introduction: Chronic respiratory diseases (CRD) are obvious effects of air pollution and the third reason of death in developing countries. In Africa, air pollution from road traffic is one of the main causes of poor air quality. We set out to systematically review existing published researches on traffic related to air pollution and CRD, particularly asthma and Chronic Obstructive Pulmonary Disease (COPD) in Africa. Methods: A literature search of PubMed, Scholar and LISSA databases, published journals, reference articles, published up to 31 December 2016, has been done by using a research strategy procedure. Texts were reviewed for inclusion. Studies were included if they met the following criteria: 1) the relationship between asthma or COPD with ambient air pollution related to road traffic was studied and 2) the population included people from Africa or lived in Africa. Articles written in English and French were included. Results: Fifty-five articles were selected in this review, of which twenty-seven were on air pollution and CRD in Africa. The proximity of the residence or workplace to the traffic is associated with an increased risk of asthma with a dose-response relationship. The estimated prevalence of COPD varies between 2.7% and 38.5%. Conclusion: There is little research on traffic related to air pollution and CRD in Africa. Strategies to reduce traffic related to air pollution in African cities have been proposed in order to have a healthier ambient air.
文摘The Sahelian regions have experienced a drought that has made them vulnerable to hydro-climatic conditions. Strategies have been developed to re</span><span style="font-family:Verdana;">duce this vulnerability. The governments of Senegal, Mauritania, Mali and Guinea</span><span style="font-family:Verdana;"> have created the Organization for the development of the Senegal River (OMVS in french) with the aim of realizing large hydraulic installations. This resulted in the construction of the Diama and Manantali dams in the Senegal River Basin. The first aims to stop the saline intrusion, the second to regulate the flow of the river, to allow the irrigation of agricultural perimeters, and to produce electrical energy. The impoundment of the Diama dam has modified the hydraulic behavior of the estuary. The purpose of this study is to carry out </span><span style="font-family:Verdana;">the hydraulic modeling of the estuary of Senegal river downstream of the Diama Dam in transient mode by the HEC-RAS software. Two geometric models were </span><span style="font-family:Verdana;">constructed on the basis of a digital terrain model (DTM) using the Arc-GIS and HEC GeoRAS soft wares after processing the collected topographic data. The first geometric model, of which the areas of Senegal river downstream Diama Dam have been represented by cross-section, is one-dimensional. The </span><span style="font-family:Verdana;">second one is also one dimensional;in this model, the area of the Senegal River </span><span style="font-family:Verdana;">estuary downstream Diama Dam is introduced as water storage zones. The components of these models are the stream sections, lateral links, and storage areas. The flood hydrograph downstream Diama Dam is introduced as conditions at the upstream limits of the models while the tidal is introduced as a downstream condition. After the stability and calibration, the results given by HEC-RAS simulations are the variations of the water levels, the temporal variations of the flow rates for each section, the maximum flow velocities and the propagation times of the flood waves. The analysis and comparisons of these results strongly suggest using HEC-RAS issues as a decision-making tool helping to manage floods during times of crisis.
文摘Bioactive compounds in plants are associated with the reduction of chronic diseases. The free radical scavenging activity of different extracts of a medicinal plant, </span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"><i></span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><i><span style="font-family:Verdana;">Sclerocarya</span></i></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"> <i>birrea</i></span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><i><span style="font-family:Verdana;"></i></span></i></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">, has been investigated using the DPPH test, ABTS test and FRAP. Three extracts were prepared from the leaves and bark: hydro-methanolic, hydro-acetonic and aqueous. Phytochemical screening was carried out the standard methods followed by the determination of the polyphenol by Folin-Ciocalteu method. The analysis of variance (ANOVA) with the STATISTICA 7.1 and statistical significance was set at p </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"><</span></span></span><span><span><span style="font-family:""><span style="font-family:Verdana;"> 0.05. Evolution of percent inhibition (PI) as well as the IC</span><sub><span style="font-family:Verdana;">50</span></sub><span style="font-family:Verdana;"> of the extracts w</span></span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">as</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"> obtained using the Origin Pro 8.5 software and Microsoft Excel. The results show that the bark extracts are about twice as rich in polyphenols as the leaves. With DPPH at 1.25 mg/mL, the bark has a PI of 91.04% ± 0.001% while leaves, reach 99.80% ± 0.021%. As for the ABTS test, the bark extract reached its maximum activity at 1.25 mg/m</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">L</span></span></span><span><span><span style="font-family:""><span style="font-family:Verdana;"> with a PI of 99.80% ± 0.003% while leaves extract greater value of PI is 99.75 ± 0.003 at 2.5 mg/mL. With FRAP test at 1.25 mg/mL, the bark has a PI of 79.29% ± 0.005% while leaves, reach 80.33% ± 0.001%. The IC</span><sub><span style="font-family:Verdana;">50</span></sub><span style="font-family:Verdana;"> of the bark and leaf extracts on the smallest DPPH are 0.156 ± 0.001 mg/mL in hydro-methanol, 0.301 ± 0.00 mg/mL in hydro-acetone and 0.407 ± 0.00 mg/mL in aqueous extract. With ABTS test, the best IC</span><sub><span style="font-family:Verdana;">50</span></sub><span style="font-family:Verdana;"> are obtained with hydro-acetone extracts with value of 0.247 ± 0.001 </span><span style="font-family:Verdana;">mg/mL for bark and 0.248 ± 0.0005 mg/mL for leaves while in hydro-methanolic</span><span style="font-family:Verdana;"> and aqueous extracts the best IC</span><sub><span style="font-family:Verdana;">50</span></sub><span style="font-family:Verdana;"> are respectively 0.255 ± 0.00 mg/mL and 0.463 ± 0.00 mg/mL. Using ascorbic acid as our standard, the PI was 94.86% ± 0.008% with an IC</span><sub><span style="font-family:Verdana;">50</span></sub><span style="font-family:Verdana;"> of 0.213 ± 0.00 mg/mL. According to these results, the reducing power of the bark is slightly higher than that of the leaves. We can say that the bark has better activity than the leaves and the alcoholic extracts have given better results than the aqueous extract.
文摘Introduction: To describe the epidemiologic profile, clinical and paraclinical of diabetics presenting microalbuminuria at Marc Sankale center. Patients and methods: We have done cross-sectional and retrospective study in a descriptive and analytic view or way. It happened within 6 months. Diabetic patients who performed the nycthemeral urinary albumin dose and mentioned in the file were included. The last study is considered as a positive one from 30 to 299mg/24h: Microalbuminuria. The creatinine has been noted and the clearing of the creatinine is calculated through the formula of Cockcroft and Gault. The statistical analysis of data has been done thanks to software such as excel 2013 and SPSS VER 18.0. Results: 221 patients have been noted with 70% women and 30% men. The age varied between 30 years and 85 years with an average of 56, 62 against 9.97 years. Sixty three (63) patients have microalbuminuria (29%);creatinine has been regularized to 25 patients with 14.8% of cases. Among the microalbuminuria patients having completed the creatinine, 32 patients (42.7%) and 16 (21.3%) are respectively in a state of chronical renal failure, light and moderated. Conclusion: The microalbuminuria is frequent to diabetics. But in our series a starting renal insufficiency could precede that microalbuminuria.
文摘Water is the main limiting factor in the cultivation of tomato (<i>Solanum lyco<span>persicum</span></i><span> L.) in Senegal. Thus, the selection of varieties tolerant to water st</span>ress would be an alternative solution for their production. <i>In vitro </i>germination, growth, total chlorophyll and proline levels were studied in five varieties of tomato subjected to increasing osmotic pressures (0, 5, 10 and 15 kPa) thanks to the PEG-8000 incorporated in an MS/2 medium for 30 days. A strong sen<span>sitivity to water stress for <i>in vitro</i> seed germination in the <i>Rodeo</i> variety (4</span>1%) is recorded at 5 kPa and maintained at 15 kPa (20.83%) while it was only noticed at 15 kPa in the other tomato varieties. The <i>Xewel</i> and <i>Lady Nema</i> varieties obtained the smallest reductions in the number of leaves of vitroplants, with 30.79% and 27.97% at 15 kPa, respectively, and the <i>Rodeo</i> variety recorded a reduction of 35.97%. From 5 kPa, the varieties record reductions in <span>the number of secondary roots of more than 15%. The effect of osmotic pr</span>essures on decreasing the taproot height and length is not significant. The <i>Xewel </i>variety had the highest average fresh (0.483 g) and dry (0.082 g) weights of the aerial part at 15 kPa and the <i>Rodeo</i> variety </span><span style="font-family:"">had </span><span style="font-family:"">the lowest ones (0.308 g and 0.0501 g). The <i>Lady Nema</i> variety had the highest average fresh (0.171 g) and dry (0.039 g) root weights and the <i>Rodeo</i> variety</span><span style="font-family:""> had</span><span style="font-family:""> the lowest ones (0.086 and 0.020 g). The vitroplants of <i>Rodeo </i>variety recorded the highest decreases in total chlorophyll contents at all osmotic pressures and the lowest increase in proline content (53.37%) at 15 kPa. <i>A contrario</i>, the <i>Xewel</i> variety recorded the greatest increase in proline content (116.26%). Ultimately, the vitroplants of <i>Lady Nem</i>a and <i>Xewe</i>l varieties were more tolerant to water stress, the <i>Ganila </i>and<i> Mongal </i>varieties were moderately tolerant and the <i>Rodeo</i> variety was the most sensitive.
