AIM: To evaluate if canine models are appropriate for teaching endoscopy fellows the techniques of endoscopic submucosal dissection (ESD). METHODS: ESD was performed in 10 canine models under general anesthesia, on ar...AIM: To evaluate if canine models are appropriate for teaching endoscopy fellows the techniques of endoscopic submucosal dissection (ESD). METHODS: ESD was performed in 10 canine models under general anesthesia, on artificial lesions of the esophagus or stomach marked with coagulation points. After ESD, each canine model was euthanized and surgical resection of the esophagus or stomach was carried out according to "The Principles of Humane Experimental Technique, Russel and Burch". The ESD specimens were fixed with needles on cork submerged in a formol solution with the esophagus or stomach, and delivered to the pathology department to be analyzed. RESULTS: ESD was completed without complications using the Hook-knife in five esophageal areas, with a procedural duration of 124 ± 19 min, a length of 27.4 ± 2.6 mm and a width of 21 ± 2.4 mm. ESD was also completed without complications using the IT-knife2 in five gastric areas, with a procedural duration of 92.6 ± 19 min, a length of 32 ± 2.5 mm and a width of 18 ± 3.7 mm. CONCLUSION: ESD is feasible in the normal esopha- gus and stomach of canine models, which are appropriate for teaching this technique.展开更多
Introduction: Postpartum mental disorders are psychopathological states that affect women after childbirth. These disorders often negatively impact a child’s mental health and the mother-child bond. The objective of ...Introduction: Postpartum mental disorders are psychopathological states that affect women after childbirth. These disorders often negatively impact a child’s mental health and the mother-child bond. The objective of this work was to determine the frequency of mental disorders during the postpartum period at the University Community Health Center of Konobougou in Mali. Methods: This descriptive cross-sectional study took place from March 1 to July 31, 2022, for four months. Results: The study involved 201 immediate postpartum women at the Konobougou Community and University Health Center. The 20-35 age group accounted for 70.00% of the population;the average age was 24 years ± 5.95 years, with a range of 15 to 45 years. Married women made up 96.00% of the sample. The overall frequency of mental disorders was 15.92%. The mental disorders recorded were postpartum depression (5.47%), anxiety disorders (3.98%), postpartum blues (5.47%), and posttraumatic stress disorder (0.50%). Puerperal psychosis was found in 0.50% of the participants. Conclusion: This study revealed a high prevalence of mental disorders among postpartum women in Konobougou, Mali. During postnatal consultations, health workers should prioritize screening for mental health disorders.展开更多
BACKGROUND Simulated microgravity environment can lead to gastrointestinal motility disturbance.The pathogenesis of gastrointestinal motility disorders is closely related to the stem cell factor(SCF)/c-kit signaling p...BACKGROUND Simulated microgravity environment can lead to gastrointestinal motility disturbance.The pathogenesis of gastrointestinal motility disorders is closely related to the stem cell factor(SCF)/c-kit signaling pathway associated with intestinal flora and Cajal stromal cells.Moreover,intestinal flora can also affect the regulation of SCF/c-kit signaling pathway,thus affecting the expression of Cajal stromal cells.Cajal cells are the pacemakers of gastrointestinal motility.AIM To investigate the effects of Bifidobacterium lactis(B.lactis)BLa80 on the intestinal flora of rats in simulated microgravity and on the gastrointestinal motility-related SCF/c-kit pathway.METHODS The internationally recognized tail suspension animal model was used to simulate the microgravity environment,and 30 rats were randomly divided into control group,tail suspension group and drug administration tail suspension group with 10 rats in each group for a total of 28 days.The tail group was given B.lactis BLa80 by intragastric administration,and the other two groups were given water intragastric administration,the concentration of intragastric administration was 0.1 g/mL,and each rat was 1 mL/day.Hematoxylin&eosin staining was used to observe the histopathological changes in each segment of the intestine of each group,and the expression levels of SCF,c-kit,extracellular signal-regulated kinase(ERK)and p-ERK in the gastric antrum of each group were detected by Western blotting and PCR.The fecal flora and mucosal flora of rats in each group were detected by 16S rRNA.RESULTS Simulated microgravity resulted in severe exfoliation of villi of duodenum,jejunum and ileum in rats,marked damage,increased space between villi,loose arrangement,shortened columnar epithelium of colon,less folds,narrower mucosal thickness,reduced goblet cell number and crypts,and significant improvement after probiotic intervention.Simulated microgravity reduced the expressions of SCF and c-kit,and increased the expressions of ERK and P-ERK in the gastric antrum of rats.However,after probiotic intervention,the expressions of SCF and ckit were increased,while the expressions of ERK and P-ERK were decreased,with statistical significance(P<0.05).In addition,simulated microgravity can reduce the operational taxonomic unit(OTU)of the overall intestinal flora of rats,B.lactis BLa80 can increase the OTU of rats,simulated microgravity can reduce the overall richness and diversity of stool flora of rats,increase the abundance of firmicutes in stool flora of rats,and reduce the abundance of Bacteroides in stool flora of rats,most of which are mainly beneficial bacteria.Simulated microgravity can increase the overall richness and diversity of mucosal flora,increase the abundance of Bacteroides and Desulphurides in the rat mucosal flora,and decrease the abundance of firmicutes,most of which are proteobacteria.After probiotics intervention,the overall Bacteroidetes trend in simulated microgravity rats was increased.CONCLUSION B.lactis BLa80 can ameliorate intestinal mucosal injury,regulate intestinal flora,inhibit ERK expression,and activate the SCF/c-kit signaling pathway,which may have a facilitating effect on gastrointestinal motility in simulated microgravity rats.展开更多
The centroid coordinate serves as a critical control parameter in motion systems,including aircraft,missiles,rockets,and drones,directly influencing their motion dynamics and control performance.Traditional methods fo...The centroid coordinate serves as a critical control parameter in motion systems,including aircraft,missiles,rockets,and drones,directly influencing their motion dynamics and control performance.Traditional methods for centroid measurement often necessitate custom equipment and specialized positioning devices,leading to high costs and limited accuracy.Here,we present a centroid measurement method that integrates 3D scanning technology,enabling accurate measurement of centroid across various types of objects without the need for specialized positioning fixtures.A theoretical framework for centroid measurement was established,which combined the principle of the multi-point weighing method with 3D scanning technology.The measurement accuracy was evaluated using a designed standard component.Experimental results demonstrate that the discrepancies between the theoretical and the measured centroid of a standard component with various materials and complex shapes in the X,Y,and Z directions are 0.003 mm,0.009 mm,and 0.105 mm,respectively,yielding a spatial deviation of 0.106 mm.Qualitative verification was conducted through experimental validation of three distinct types.They confirmed the reliability of the proposed method,which allowed for accurate centroid measurements of various products without requiring positioning fixtures.This advancement significantly broadened the applicability and scope of centroid measurement devices,offering new theoretical insights and methodologies for the measurement of complex parts and systems.展开更多
Emergency department nurses face severe occupational stress leading to anxiety,depression,and burnout,which significantly impair their well-being and patientcare quality.This narrative review examined the role of mind...Emergency department nurses face severe occupational stress leading to anxiety,depression,and burnout,which significantly impair their well-being and patientcare quality.This narrative review examined the role of mindfulness-based stress reduction(MBSR)in addressing these challenges.Rooted in nonjudgmental present-moment awareness,MBSR enhances emotional regulation and reduces psychological distress by fostering adaptive coping strategies.Studies have demonstrated its efficacy in lowering anxiety,depressive symptoms,and emotional exhaustion,while improving workplace well-being,empathy,and job satisfaction.Mechanistically,MBSR improves interoceptive awareness and autonomic balance,as evidenced by physiological markers such as heart rate variability.However,gaps remain in long-term efficacy assessments,personalized interventions,and integration with multidisciplinary approaches.Future research should prioritize tailored biomarker-driven programs,longitudinal studies,and scalable implementation strategies in high-stress clinical settings.This review underscores MBSR’s potential as a sustainable,evidence-based tool to enhance emergency department nurses’mental health and professional performance,advocating for broader adoption and further refinement of its practical applications.展开更多
With the rapid development of wearable electronic skin technology, flexible strain sensors have shown great application prospects in the fields of human motion and physiological signal detection, medical diagnostics, ...With the rapid development of wearable electronic skin technology, flexible strain sensors have shown great application prospects in the fields of human motion and physiological signal detection, medical diagnostics, and human-computer interaction owing to their outstanding sensing performance. This paper reports a strain sensor with synergistic conductive network, consisting of stable carbon nanotube dispersion (CNT) layer and brittle MXene layer by dip-coating and electrostatic self-assembly method, and breathable three-dimensional (3D) flexible substrate of thermoplastic polyurethane (TPU) fibrous membrane prepared through electrospinning technology. The MXene/CNT@PDA-TPU (MC@p-TPU) flexible strain sensor had excellent air permeability, wide operating range (0–450 %), high sensitivity (Gauge Factor, GFmax = 8089.7), ultra-low detection limit (0.05 %), rapid response and recovery times (40 ms/60 ms), and excellent cycle stability and durability (10,000 cycles). Given its superior strain sensing capabilities, this sensor can be applied in physiological signals detection, human motion pattern recognition, and driving exoskeleton robots. In addition, MC@p-TPU fibrous membrane also exhibited excellent photothermal conversion performance and can be used as a wearable photo-heater, which has far-reaching application potential in the photothermal therapy of human joint diseases.展开更多
Efficient lubrication of magnesium alloys is a highly challenging topic in the field of tribology.In this study,magnesium silicate hydroxide(MSH)nanotubes with serpentine structures were synthesized.The tribological b...Efficient lubrication of magnesium alloys is a highly challenging topic in the field of tribology.In this study,magnesium silicate hydroxide(MSH)nanotubes with serpentine structures were synthesized.The tribological behavior of AZ91D magnesium alloy rubbed against GCr15 steel was studied under lubricating oil with surface-modified MSH nanotubes as additives.The effects of the concentration,applied load,and reciprocating frequency on the friction and wear of the AZ91D alloy were studied using an SRV-4 sliding wear tester.Results show a decrease of 18.7–68.5%in friction coefficient,and a reduction of 19.4–54.3%in wear volume of magnesium alloy can be achieved by applying the synthetic serpentine additive under different conditions.A suspension containing 0.3 wt.%MSH was most efficient in reducing wear and friction.High frequency and medium load were more conducive to improving the tribological properties of magnesium alloys.A series of beneficial physical and chemical processes occurring at the AZ91D alloy/steel interface can be used to explain friction and wear reduction based on the characterization of the morphology,chemical composition,chemical state,microstructure,and nanomechanical properties of the worn surface.The synthetic MSH,with serpentine structure and nanotube morphology,possesses excellent adsorbability,high chemical activity,and good self-lubrication and catalytic activity.Therefore,physical polishing,tribochemical reactions,and physicalchemical depositions can occur easily on the sliding contacts.A dense tribolayer with a complex composition and composite structure was formed on the worn surface.Its high hardness,good toughness and plasticity,and prominent lubricity resulted in the improvement of friction and wear,making the synthetic MSH a promising efficient oil additive for magnesium alloys under boundary and mixed lubrication.展开更多
In this work,a heterogeneous structure(HS)with an alternating distribution of coarse and fineαlamella is fabricated in bimodal Ti6242 alloy via insufficient diffusion of alloying elements induced by fast heat-ing tre...In this work,a heterogeneous structure(HS)with an alternating distribution of coarse and fineαlamella is fabricated in bimodal Ti6242 alloy via insufficient diffusion of alloying elements induced by fast heat-ing treatment.Instead of a distinct interface between the primaryα_(p)hase(α_(p))andβ_(t)ransformation microstructure(β_(t))in the equiaxed microstructure(EM),allα_(p)/β_(t)interfaces are eliminated in the HS,and the largeα_(p)phases are replaced by coarseαlamella.Compared to the EM alloy,the heterostruc-tured alloy exhibits a superior strength-ductility combination.The enhanced strength is predominantly attributed to the increased interfaces ofα/βplates and hetero-deformation induced(HDI)strengthening caused by back stress.Meanwhile,good ductility is ascribed to its uniform distribution of coarse and fineαlamella,which effectively inhibits strain localization and generates an extra HDI hardening.This can be evidenced by the accumulated geometrically necessary dislocations(GNDs)induced by strain partitioning of the heterostructure.Significantly,the HDI causes extra<c+a>dislocations piling up in the coarseαlamella,which generates an extra strain hardening to further improve the ductility.Such hetero-interface coordinated deformation mechanism sheds light on a new perspective for tailoring bimodal titanium al-loys with excellent mechanical properties.展开更多
This work investigates the transient performance and stability of CO_(2)/H_(2)O co-electrolysis in an air-free environment using a flat-tube solid oxide electrolysis cell(SOEC)stack.The results showed that the transie...This work investigates the transient performance and stability of CO_(2)/H_(2)O co-electrolysis in an air-free environment using a flat-tube solid oxide electrolysis cell(SOEC)stack.The results showed that the transient behavior of the stack with and without blowing gas into the air electrode is almost the same.With a current density of 0.67 A·cm^(-2)@750℃,the stack operated for over 200 h under co-electrolysis conditions without air blowing,and the voltage drop rate of the stack was approximately 0.203%/100 hours.Microstructure analysis revealed a significant loss of nickel particles and an apparent for-mation of an insulating phase strontium chromate(SrCrO4)on the surface of the current collection layer of the air electrode,which are identified as key factors contributing to the performance degradation of the stack.This study provides a reference for development of efficient fuel preparation technology based on SOEC stack in airless environments.展开更多
The development of new quality productivity has set new requirements for vocational education.Vocational colleges need to integrate ideological and political education into professional courses to cultivate high-quali...The development of new quality productivity has set new requirements for vocational education.Vocational colleges need to integrate ideological and political education into professional courses to cultivate high-quality talents with both technical capabilities and political literacy.This paper analyzes the connotation of new quality productivity and its reshaping of vocational education,explores the challenges faced by the educational mechanism of Curriculumbased Political and Ideological Education(CPIE),and proposes a“three-dimensional synergy”practical pathway.That is,to effectively promote CPIE through three dimensions:the deep integration of cases with professional content,the enhancement of teaching effects using digitization,and the optimization of the course evaluation system.It aims to provide theoretical support and practical references for the reform of ideological and political education in vocational colleges.展开更多
With the economic and social development of the country,vocational education is playing an increasingly significant role in cultivating highly skilled talents.However,the mechanical drawing courses in vocational colle...With the economic and social development of the country,vocational education is playing an increasingly significant role in cultivating highly skilled talents.However,the mechanical drawing courses in vocational colleges still face numerous challenges in the teaching process,such as outdated textbook content,inadequate practical resources,weak teaching staff,and low student interest.This paper aims to explore these issues and propose corresponding coping strategies.The findings of this study not only provide specific improvement suggestions for vocational colleges but also emphasize the importance of these strategies in enhancing students’comprehensive abilities and promoting the development of vocational education.By addressing these challenges,this paper contributes to the enhancement of teaching quality and the overall advancement of vocational skills education.展开更多
Rich-nickel layered ternary NCM811 has been widely used in the field of electric vehicles ascribed to its high theoretical specific capacity.However,poor cycling stability and rate-performance hindered its further dev...Rich-nickel layered ternary NCM811 has been widely used in the field of electric vehicles ascribed to its high theoretical specific capacity.However,poor cycling stability and rate-performance hindered its further development.Herein,different amounts of nitrogen-doped carbon were wrapped on the surface of NCM811 via a facile rheological phase method by regulating the amount of dopamine hydrochloride.The effects of the coating amounts on the structure and electrochemical performance are investigated.The DFT calculation,XRD,SEM and XPS reveal that an appropriate amount of nitrogen-doped carbon coating could uniformly form a protective layer on the NCM811 surface and the introduced N could anchor Ni atoms to inhibit the Li^(+)/Ni^(2+)mixing,but excessive amount would reduce Ni^(3+)to Ni^(2+)so as to conversely aggravate Li^(+)/Ni^(2+)mixing.Among the samples,the NCM811-CN0.75 sample exhibits the most excellent electrochemical performance,delivering a high-rate capacity of 151.6 mA·h/g at 10C,and long-term cyclability with 82.2%capacity retention after 300 cycles at 5C,exhibiting remarkable rate-performance and cyclability.展开更多
As humanity ventures deeper into space,our challenges become increasingly complex.Space medicine,once confi ned to ensuring the health and safety of astronauts on low-Earth orbit missions,is now tasked with ensuring t...As humanity ventures deeper into space,our challenges become increasingly complex.Space medicine,once confi ned to ensuring the health and safety of astronauts on low-Earth orbit missions,is now tasked with ensuring the health and safety of astronauts embarking on extended missions to the Moon,Mars,and beyond.Th e advancement of space medicine and the conduct of in-orbit medical experiments not only determine the boundaries of human exploration of the cosmos but also provide new insights that can benefi t human health on Earth.展开更多
In this paper,a topology optimization method for coordinated stiffness and strength design is proposed under mass constraints,utilizing the Solid Isotropic Material with Penalization approach.Element densities are reg...In this paper,a topology optimization method for coordinated stiffness and strength design is proposed under mass constraints,utilizing the Solid Isotropic Material with Penalization approach.Element densities are regulated through sensitivity filtering tomitigate numerical instabilities associatedwith stress concentrations.Ap-norm aggregation function is employed to globalize local stress constraints,and a normalization technique linearly weights strain energy and stress,transforming the multi-objective problem into a single-objective formulation.The sensitivity of the objective function with respect to design variables is rigorously derived.Three numerical examples are presented,comparing the optimized structures in terms of strain energy,mass,and stress across five different mathematical models with varying combinations of optimization objectives.The results validate the effectiveness and feasibility of the proposed method for achieving a balanced design between structural stiffness and strength.This approach offers a new perspective for future research on stiffness-strength coordinated structural optimization.展开更多
BACKGROUND Ultrasound classification can be used to determine the severity of adhesive intestinal obstruction and to guide the formulation of treatment plans.AIM To explore the value of ultrasound classification in di...BACKGROUND Ultrasound classification can be used to determine the severity of adhesive intestinal obstruction and to guide the formulation of treatment plans.AIM To explore the value of ultrasound classification in disease judgment and treatment plan formulation for patients with adhesive intestinal obstruction.METHODS The medical records of 120 patients with adhesive intestinal obstruction presenting at Taihe Hospital Affiliated with Hubei Medical College were retrospectively analyzed from January 2022 to January 2024 according to the severity of ultrasound images,divided into simple(mild),complex(moderate),and critical(severe),analyzing the imaging characteristics of patients with different ultrasound classifications,and developing the corresponding treatment plan according to the ultrasound typing results,that is,conservative treatment and surgical treatment,contrast the ultrasound signs of patients in the conservative vs surgical treatment groups,and the value of ultrasound classification in the treatment of adhesive ileus.RESULTS Among the 120 patients,P>0.05,compared with the general data(sex,age,body quality index,time to onset,and history of onset),the proportion of bowel distension and abdominal effusion(P>0.05),and the proportion of adhesion mass and cross-cross in the conservative treatment group,P<0.05.CONCLUSION Ultrasound typing can aid in the clinical evaluation of the severity of adhesive intestinal obstruction and provide an imaging reference for clinicians to develop targeted treatment plans.展开更多
Rationale:Advances in sleep research have introduced medications like lemborexant,a dual orexin receptor antagonist.While effective for regulating sleep,overdoses are a concern,especially in suicide attempts.However,l...Rationale:Advances in sleep research have introduced medications like lemborexant,a dual orexin receptor antagonist.While effective for regulating sleep,overdoses are a concern,especially in suicide attempts.However,limited data exist on lemborexant overdose,prompting this case report to elucidate its clinical course.Patient’s Concern:A 91-year-old Japanese woman with multiple comorbidities,including insomnia and chronic kidney disease,was admitted after ingesting 315 mg of lemborexant in a suicide attempt.Diagnosis:Lemborexant overdose.Interventions:Supportive care with 500 mL of Ringer’s acetate solution at the emergency room.Outcomes:She gradually regained full consciousness with no residual deficits.Due to persistent suicidal ideation,she was transferred to a psychiatric hospital after seven days of supportive care.Lessons:A review of four lemborexant overdose cases managed at our hospital revealed that overdoses primarily induce altered consciousness and are unlikely to cause organ dysfunction.Supportive care is generally sufficient for management.However,given the limited data,further case accumulation is needed to enhance clinical understanding.展开更多
This paper investigates a wireless powered communication network(WPCN)facilitated by an unmanned aerial vehicle(UAV)in Internet of Things(IoT)networks,where multiple IoT devices(IoTDs)gather energy from a terrestrial ...This paper investigates a wireless powered communication network(WPCN)facilitated by an unmanned aerial vehicle(UAV)in Internet of Things(IoT)networks,where multiple IoT devices(IoTDs)gather energy from a terrestrial energy station(ES)during the wireless energy transfer(WET)stage,followed by the UAV collecting data from these powered IoTDs with the time division multiple access(TDMA)protocol in the wireless information transfer(WIT)stage.To overcome the challenges of radio propagation caused by obstructions,we incorporate a reconfigurable intelligent surface(RIS)to enhance the link quality of the ES-IoTDs and IoTDs-UAV.The primary objective is to maximize the average sum rate of all IoTDs by jointly optimizing UAV trajectory,ES transmit power,and RIS phase shifts,along with the time allocation for WET and WIT.To this end,we reformulate the optimization problem as a markov decision process(MDP)and introduce a deep reinforcement learning(DRL)approach for addressing the formulated problem,called the proximal policy optimization(PPO)based energy harvesting with trajectory design and phase shift optimization(PPO-EHTDPS)algorithm.By continuously exploring within the environment,the PPO algorithm refines its policy to optimize the UAV trajectory,the energy phase shifts,ES transmit power,and WET/WIT time allocation.Additionally,a continuous phase shift optimization algorithm is employed to determine the information phase shifts for each IoTD to maximize average sum rate.Finally,numerical results demonstrate that the proposed PPOEHTDPS algorithm can significantly achieve higher average sum rate and show better convergence performance over the benchmark algorithms.展开更多
Rice,as a primary commodity,needs to be increased in production while facing the sustainability challenges of limited land,water resources,and climate change.The demand for rice productivity was not enough to rely onl...Rice,as a primary commodity,needs to be increased in production while facing the sustainability challenges of limited land,water resources,and climate change.The demand for rice productivity was not enough to rely only on the fertile fields’ability;it is necessary to consider the rainfed land potential.Cultivation in rainfed land involves biophysical pressure,lowproduction,and limited access to superior varieties.Participatory rice breeding aimed to identify farmers’trait preferences and develop acceptable lines.A bottom-up approach involved 203 farmers from four rainfed fields in Indonesia,i.e.,Semarang-Central Java,Kulon Progo-Yogyakarta,Tabanan-Bali,andGunungkidul-Yogyakarta.The experiment on February-June 2024 tested six lines(G2,G3,G4,G5,G9,and G10)and four varieties(Situ Bagendit,Gamagora7,Inpari IRNutri Zinc,and Inpago12 Agritan).Farmers’involvement in evaluating the suitability of genotypes involved using Multidimensional Scaling and Importance-Performance Analysis.Breeders added comprehensive analysis in the growing environment with Genotype Environment Interaction,and key attributes of leverage analysis from farmers must be considered.Genotype performance in the Multidimensional Scaling feasibility indicated that yield primary determinants were panicle type,disease resistance,leaf characteristics,and environmental resilience.Importance Performance Analysis verified that G3,G9,G2,and G4 had a preference at the farm level.Genotype Environment Interaction reveals that G3,G4,and G2 were ideal lines with high potential yields,suitability,and adaptability on rainfed land.Participatory rice breeding in rainfed land integrates farmers’assessments and breeders’observations to realize the most preferred genotypes according to the challenges for sustainable agriculture.展开更多
Objective:To evaluate the efficacy and safety of transcutaneous electrical acupoint stimulation(TEAS)for muscle atrophy in patients with immobilization after surgical fixation of foot and ankle fractures.Methods:This ...Objective:To evaluate the efficacy and safety of transcutaneous electrical acupoint stimulation(TEAS)for muscle atrophy in patients with immobilization after surgical fixation of foot and ankle fractures.Methods:This was a two-arm randomized controlled trial wherein 80 patients were recruited and divided into control(n=40)and intervention(n=40)groups.The control group received conventional orthopedic treatment,whereas the intervention group received TEAS and conventional treatment.The intervention group received TEAS 3 times a week for 30 min each time for 8 weeks.The primary out-comes were muscle thickness(MT)and cross-sectional area(CSA)of the rectus femoris and gastroc-nemius muscles,whereas the secondary outcome measure was echo intensity(EI).Data were collected before the fixation operations(baseline assessment)and 4 and 8 weeks after intervention.Results:Compared with baseline,the MT and CSA were reduced in both groups by the end of treatment,whereas EI increased in both groups.At week 4,the reduction in the rectus femoris CSA in the inter-vention group was significantly lower than that in the control group(P=0.02);however,the between-group differences in the MT and EI(all P>0.05)were not significant.No serious adverse events were observed in either group.Conclusion:Our study showed that TEAS can improve muscle atrophy by attenuating the decline in the muscle CSA.Because this was only a pilot trial,subsequent studies will need longer follow-ups and larger sample sizes.展开更多
The increasing challenges of environmental degradation,soil erosion,and climate change have driven interest in sustainable solutions like enhanced weathering(EW)and phytoremediation.Elephant Grass(Cenchrus purpureus),...The increasing challenges of environmental degradation,soil erosion,and climate change have driven interest in sustainable solutions like enhanced weathering(EW)and phytoremediation.Elephant Grass(Cenchrus purpureus),a fast-growing perennial species,shows promise as a bioaccumulator and agent for soil weathering.This study assessed the potential of C.purpureus to improve soil quality through heavy metal(HM)uptake and EW facilitation.A 60-day greenhouse pot experiment at Jackson State University evaluated plant performance in soils amended with metabasalt rock powder at 1:1 and 2:1 rock-to-soil ratios.Biomass,growth,and HM concentrations in roots and shoots were measured via ICP-MS after wet digestion.Soil pH and magnesium(Mg)release were also monitored to assess weathering and carbon drawdown.Results showed that C.purpureus accumulated more HMs in roots at higher amendment levels,while at lower levels,metals like As,Cd,and Cr were more translocated to shoots,enhancing phytoextraction potential.High treatment favored Fe and Al uptake,possibly reducing toxic metal accumulation in edible parts.Notably,C.purpureus contributed to the weathering of 38%of metabasalt rock,leading to a 42%increase in Mg release.With high biomass,HM tolerance,and weathering capacity,C.purpureus offers a sustainable strategy for soil remediation,improved soil health,and potential support for renewable energy systems.展开更多
文摘AIM: To evaluate if canine models are appropriate for teaching endoscopy fellows the techniques of endoscopic submucosal dissection (ESD). METHODS: ESD was performed in 10 canine models under general anesthesia, on artificial lesions of the esophagus or stomach marked with coagulation points. After ESD, each canine model was euthanized and surgical resection of the esophagus or stomach was carried out according to "The Principles of Humane Experimental Technique, Russel and Burch". The ESD specimens were fixed with needles on cork submerged in a formol solution with the esophagus or stomach, and delivered to the pathology department to be analyzed. RESULTS: ESD was completed without complications using the Hook-knife in five esophageal areas, with a procedural duration of 124 ± 19 min, a length of 27.4 ± 2.6 mm and a width of 21 ± 2.4 mm. ESD was also completed without complications using the IT-knife2 in five gastric areas, with a procedural duration of 92.6 ± 19 min, a length of 32 ± 2.5 mm and a width of 18 ± 3.7 mm. CONCLUSION: ESD is feasible in the normal esopha- gus and stomach of canine models, which are appropriate for teaching this technique.
文摘Introduction: Postpartum mental disorders are psychopathological states that affect women after childbirth. These disorders often negatively impact a child’s mental health and the mother-child bond. The objective of this work was to determine the frequency of mental disorders during the postpartum period at the University Community Health Center of Konobougou in Mali. Methods: This descriptive cross-sectional study took place from March 1 to July 31, 2022, for four months. Results: The study involved 201 immediate postpartum women at the Konobougou Community and University Health Center. The 20-35 age group accounted for 70.00% of the population;the average age was 24 years ± 5.95 years, with a range of 15 to 45 years. Married women made up 96.00% of the sample. The overall frequency of mental disorders was 15.92%. The mental disorders recorded were postpartum depression (5.47%), anxiety disorders (3.98%), postpartum blues (5.47%), and posttraumatic stress disorder (0.50%). Puerperal psychosis was found in 0.50% of the participants. Conclusion: This study revealed a high prevalence of mental disorders among postpartum women in Konobougou, Mali. During postnatal consultations, health workers should prioritize screening for mental health disorders.
文摘BACKGROUND Simulated microgravity environment can lead to gastrointestinal motility disturbance.The pathogenesis of gastrointestinal motility disorders is closely related to the stem cell factor(SCF)/c-kit signaling pathway associated with intestinal flora and Cajal stromal cells.Moreover,intestinal flora can also affect the regulation of SCF/c-kit signaling pathway,thus affecting the expression of Cajal stromal cells.Cajal cells are the pacemakers of gastrointestinal motility.AIM To investigate the effects of Bifidobacterium lactis(B.lactis)BLa80 on the intestinal flora of rats in simulated microgravity and on the gastrointestinal motility-related SCF/c-kit pathway.METHODS The internationally recognized tail suspension animal model was used to simulate the microgravity environment,and 30 rats were randomly divided into control group,tail suspension group and drug administration tail suspension group with 10 rats in each group for a total of 28 days.The tail group was given B.lactis BLa80 by intragastric administration,and the other two groups were given water intragastric administration,the concentration of intragastric administration was 0.1 g/mL,and each rat was 1 mL/day.Hematoxylin&eosin staining was used to observe the histopathological changes in each segment of the intestine of each group,and the expression levels of SCF,c-kit,extracellular signal-regulated kinase(ERK)and p-ERK in the gastric antrum of each group were detected by Western blotting and PCR.The fecal flora and mucosal flora of rats in each group were detected by 16S rRNA.RESULTS Simulated microgravity resulted in severe exfoliation of villi of duodenum,jejunum and ileum in rats,marked damage,increased space between villi,loose arrangement,shortened columnar epithelium of colon,less folds,narrower mucosal thickness,reduced goblet cell number and crypts,and significant improvement after probiotic intervention.Simulated microgravity reduced the expressions of SCF and c-kit,and increased the expressions of ERK and P-ERK in the gastric antrum of rats.However,after probiotic intervention,the expressions of SCF and ckit were increased,while the expressions of ERK and P-ERK were decreased,with statistical significance(P<0.05).In addition,simulated microgravity can reduce the operational taxonomic unit(OTU)of the overall intestinal flora of rats,B.lactis BLa80 can increase the OTU of rats,simulated microgravity can reduce the overall richness and diversity of stool flora of rats,increase the abundance of firmicutes in stool flora of rats,and reduce the abundance of Bacteroides in stool flora of rats,most of which are mainly beneficial bacteria.Simulated microgravity can increase the overall richness and diversity of mucosal flora,increase the abundance of Bacteroides and Desulphurides in the rat mucosal flora,and decrease the abundance of firmicutes,most of which are proteobacteria.After probiotics intervention,the overall Bacteroidetes trend in simulated microgravity rats was increased.CONCLUSION B.lactis BLa80 can ameliorate intestinal mucosal injury,regulate intestinal flora,inhibit ERK expression,and activate the SCF/c-kit signaling pathway,which may have a facilitating effect on gastrointestinal motility in simulated microgravity rats.
基金supported by National Natural Science Foundation of China(No.52176122).
文摘The centroid coordinate serves as a critical control parameter in motion systems,including aircraft,missiles,rockets,and drones,directly influencing their motion dynamics and control performance.Traditional methods for centroid measurement often necessitate custom equipment and specialized positioning devices,leading to high costs and limited accuracy.Here,we present a centroid measurement method that integrates 3D scanning technology,enabling accurate measurement of centroid across various types of objects without the need for specialized positioning fixtures.A theoretical framework for centroid measurement was established,which combined the principle of the multi-point weighing method with 3D scanning technology.The measurement accuracy was evaluated using a designed standard component.Experimental results demonstrate that the discrepancies between the theoretical and the measured centroid of a standard component with various materials and complex shapes in the X,Y,and Z directions are 0.003 mm,0.009 mm,and 0.105 mm,respectively,yielding a spatial deviation of 0.106 mm.Qualitative verification was conducted through experimental validation of three distinct types.They confirmed the reliability of the proposed method,which allowed for accurate centroid measurements of various products without requiring positioning fixtures.This advancement significantly broadened the applicability and scope of centroid measurement devices,offering new theoretical insights and methodologies for the measurement of complex parts and systems.
文摘Emergency department nurses face severe occupational stress leading to anxiety,depression,and burnout,which significantly impair their well-being and patientcare quality.This narrative review examined the role of mindfulness-based stress reduction(MBSR)in addressing these challenges.Rooted in nonjudgmental present-moment awareness,MBSR enhances emotional regulation and reduces psychological distress by fostering adaptive coping strategies.Studies have demonstrated its efficacy in lowering anxiety,depressive symptoms,and emotional exhaustion,while improving workplace well-being,empathy,and job satisfaction.Mechanistically,MBSR improves interoceptive awareness and autonomic balance,as evidenced by physiological markers such as heart rate variability.However,gaps remain in long-term efficacy assessments,personalized interventions,and integration with multidisciplinary approaches.Future research should prioritize tailored biomarker-driven programs,longitudinal studies,and scalable implementation strategies in high-stress clinical settings.This review underscores MBSR’s potential as a sustainable,evidence-based tool to enhance emergency department nurses’mental health and professional performance,advocating for broader adoption and further refinement of its practical applications.
基金supported by the National Natural Science Foundation of China(Nos.52373093 and 12072325)the Outstanding Youth Fund of Henan Province(No.242300421062)+1 种基金National Key R&D Program of China(No.2019YFA0706802)the 111 project(No.D18023).
文摘With the rapid development of wearable electronic skin technology, flexible strain sensors have shown great application prospects in the fields of human motion and physiological signal detection, medical diagnostics, and human-computer interaction owing to their outstanding sensing performance. This paper reports a strain sensor with synergistic conductive network, consisting of stable carbon nanotube dispersion (CNT) layer and brittle MXene layer by dip-coating and electrostatic self-assembly method, and breathable three-dimensional (3D) flexible substrate of thermoplastic polyurethane (TPU) fibrous membrane prepared through electrospinning technology. The MXene/CNT@PDA-TPU (MC@p-TPU) flexible strain sensor had excellent air permeability, wide operating range (0–450 %), high sensitivity (Gauge Factor, GFmax = 8089.7), ultra-low detection limit (0.05 %), rapid response and recovery times (40 ms/60 ms), and excellent cycle stability and durability (10,000 cycles). Given its superior strain sensing capabilities, this sensor can be applied in physiological signals detection, human motion pattern recognition, and driving exoskeleton robots. In addition, MC@p-TPU fibrous membrane also exhibited excellent photothermal conversion performance and can be used as a wearable photo-heater, which has far-reaching application potential in the photothermal therapy of human joint diseases.
基金support from the National Natural Science Foundation of China(grant number 52075544)Innovation Funds of Jihua Laboratory(X220971UZ230)+1 种基金Basic and Applied Basic Research Foundation of Guangdong Province(2022A1515110649)Funds from Research Platforms of Guangdong Higher Education Institutes(2022ZDJS038).
文摘Efficient lubrication of magnesium alloys is a highly challenging topic in the field of tribology.In this study,magnesium silicate hydroxide(MSH)nanotubes with serpentine structures were synthesized.The tribological behavior of AZ91D magnesium alloy rubbed against GCr15 steel was studied under lubricating oil with surface-modified MSH nanotubes as additives.The effects of the concentration,applied load,and reciprocating frequency on the friction and wear of the AZ91D alloy were studied using an SRV-4 sliding wear tester.Results show a decrease of 18.7–68.5%in friction coefficient,and a reduction of 19.4–54.3%in wear volume of magnesium alloy can be achieved by applying the synthetic serpentine additive under different conditions.A suspension containing 0.3 wt.%MSH was most efficient in reducing wear and friction.High frequency and medium load were more conducive to improving the tribological properties of magnesium alloys.A series of beneficial physical and chemical processes occurring at the AZ91D alloy/steel interface can be used to explain friction and wear reduction based on the characterization of the morphology,chemical composition,chemical state,microstructure,and nanomechanical properties of the worn surface.The synthetic MSH,with serpentine structure and nanotube morphology,possesses excellent adsorbability,high chemical activity,and good self-lubrication and catalytic activity.Therefore,physical polishing,tribochemical reactions,and physicalchemical depositions can occur easily on the sliding contacts.A dense tribolayer with a complex composition and composite structure was formed on the worn surface.Its high hardness,good toughness and plasticity,and prominent lubricity resulted in the improvement of friction and wear,making the synthetic MSH a promising efficient oil additive for magnesium alloys under boundary and mixed lubrication.
基金financially supported by the National Natural Science Foundation of China(Nos.52161019 and 52271054)the Science and Technology Project of Guizhou Province,China(No.[2023]047)+1 种基金the GuiZhou DIIT Innovation Project(No.[2023]153)the One Hundred Person Project of Guizhou Province,China(No.[2020]6006).
文摘In this work,a heterogeneous structure(HS)with an alternating distribution of coarse and fineαlamella is fabricated in bimodal Ti6242 alloy via insufficient diffusion of alloying elements induced by fast heat-ing treatment.Instead of a distinct interface between the primaryα_(p)hase(α_(p))andβ_(t)ransformation microstructure(β_(t))in the equiaxed microstructure(EM),allα_(p)/β_(t)interfaces are eliminated in the HS,and the largeα_(p)phases are replaced by coarseαlamella.Compared to the EM alloy,the heterostruc-tured alloy exhibits a superior strength-ductility combination.The enhanced strength is predominantly attributed to the increased interfaces ofα/βplates and hetero-deformation induced(HDI)strengthening caused by back stress.Meanwhile,good ductility is ascribed to its uniform distribution of coarse and fineαlamella,which effectively inhibits strain localization and generates an extra HDI hardening.This can be evidenced by the accumulated geometrically necessary dislocations(GNDs)induced by strain partitioning of the heterostructure.Significantly,the HDI causes extra<c+a>dislocations piling up in the coarseαlamella,which generates an extra strain hardening to further improve the ductility.Such hetero-interface coordinated deformation mechanism sheds light on a new perspective for tailoring bimodal titanium al-loys with excellent mechanical properties.
基金co-supported by the National Key R&D Program of China(No.2022YFB4002203)Baima Lake Laboratory Joint Funds of the Zhejiang Provincial Natural Science Foundation of China(No.LBMHY24B060003)Ningbo Key R&D Project(No.2023Z155).
文摘This work investigates the transient performance and stability of CO_(2)/H_(2)O co-electrolysis in an air-free environment using a flat-tube solid oxide electrolysis cell(SOEC)stack.The results showed that the transient behavior of the stack with and without blowing gas into the air electrode is almost the same.With a current density of 0.67 A·cm^(-2)@750℃,the stack operated for over 200 h under co-electrolysis conditions without air blowing,and the voltage drop rate of the stack was approximately 0.203%/100 hours.Microstructure analysis revealed a significant loss of nickel particles and an apparent for-mation of an insulating phase strontium chromate(SrCrO4)on the surface of the current collection layer of the air electrode,which are identified as key factors contributing to the performance degradation of the stack.This study provides a reference for development of efficient fuel preparation technology based on SOEC stack in airless environments.
基金supported by the Beijing Municipal Commission of Education(Project Leader:Shang Wang,Project No.ZYJYDJ2024049).
文摘The development of new quality productivity has set new requirements for vocational education.Vocational colleges need to integrate ideological and political education into professional courses to cultivate high-quality talents with both technical capabilities and political literacy.This paper analyzes the connotation of new quality productivity and its reshaping of vocational education,explores the challenges faced by the educational mechanism of Curriculumbased Political and Ideological Education(CPIE),and proposes a“three-dimensional synergy”practical pathway.That is,to effectively promote CPIE through three dimensions:the deep integration of cases with professional content,the enhancement of teaching effects using digitization,and the optimization of the course evaluation system.It aims to provide theoretical support and practical references for the reform of ideological and political education in vocational colleges.
基金support from the Science and Technology Key Project of Beijing Polytechnic(Project Leader:Jinru Ma,No.2024X008-KXZ).
文摘With the economic and social development of the country,vocational education is playing an increasingly significant role in cultivating highly skilled talents.However,the mechanical drawing courses in vocational colleges still face numerous challenges in the teaching process,such as outdated textbook content,inadequate practical resources,weak teaching staff,and low student interest.This paper aims to explore these issues and propose corresponding coping strategies.The findings of this study not only provide specific improvement suggestions for vocational colleges but also emphasize the importance of these strategies in enhancing students’comprehensive abilities and promoting the development of vocational education.By addressing these challenges,this paper contributes to the enhancement of teaching quality and the overall advancement of vocational skills education.
基金Project(2021H0028) supported by the Natural Scienceof Fujian Province,ChinaProject(JAT200455) supported by the Fujian Provincial Young and Middle-aged Teacher Education Project,ChinaProject(fma2023003) supported by the Open Fund of Fujian Provincial Key Laboratory of Functional Materials and Applications,China。
文摘Rich-nickel layered ternary NCM811 has been widely used in the field of electric vehicles ascribed to its high theoretical specific capacity.However,poor cycling stability and rate-performance hindered its further development.Herein,different amounts of nitrogen-doped carbon were wrapped on the surface of NCM811 via a facile rheological phase method by regulating the amount of dopamine hydrochloride.The effects of the coating amounts on the structure and electrochemical performance are investigated.The DFT calculation,XRD,SEM and XPS reveal that an appropriate amount of nitrogen-doped carbon coating could uniformly form a protective layer on the NCM811 surface and the introduced N could anchor Ni atoms to inhibit the Li^(+)/Ni^(2+)mixing,but excessive amount would reduce Ni^(3+)to Ni^(2+)so as to conversely aggravate Li^(+)/Ni^(2+)mixing.Among the samples,the NCM811-CN0.75 sample exhibits the most excellent electrochemical performance,delivering a high-rate capacity of 151.6 mA·h/g at 10C,and long-term cyclability with 82.2%capacity retention after 300 cycles at 5C,exhibiting remarkable rate-performance and cyclability.
基金supported by the National Natural Science Foundation of China(T2192933).
文摘As humanity ventures deeper into space,our challenges become increasingly complex.Space medicine,once confi ned to ensuring the health and safety of astronauts on low-Earth orbit missions,is now tasked with ensuring the health and safety of astronauts embarking on extended missions to the Moon,Mars,and beyond.Th e advancement of space medicine and the conduct of in-orbit medical experiments not only determine the boundaries of human exploration of the cosmos but also provide new insights that can benefi t human health on Earth.
基金funded by National Nature Science Foundation of China(92266203)National Nature Science Foundation of China(52205278)+1 种基金Key Projects of Shijiazhuang Basic Research Program(241791077A)Central Guide Local Science and Technology Development Fund Project of Hebei Province(246Z1022G).
文摘In this paper,a topology optimization method for coordinated stiffness and strength design is proposed under mass constraints,utilizing the Solid Isotropic Material with Penalization approach.Element densities are regulated through sensitivity filtering tomitigate numerical instabilities associatedwith stress concentrations.Ap-norm aggregation function is employed to globalize local stress constraints,and a normalization technique linearly weights strain energy and stress,transforming the multi-objective problem into a single-objective formulation.The sensitivity of the objective function with respect to design variables is rigorously derived.Three numerical examples are presented,comparing the optimized structures in terms of strain energy,mass,and stress across five different mathematical models with varying combinations of optimization objectives.The results validate the effectiveness and feasibility of the proposed method for achieving a balanced design between structural stiffness and strength.This approach offers a new perspective for future research on stiffness-strength coordinated structural optimization.
文摘BACKGROUND Ultrasound classification can be used to determine the severity of adhesive intestinal obstruction and to guide the formulation of treatment plans.AIM To explore the value of ultrasound classification in disease judgment and treatment plan formulation for patients with adhesive intestinal obstruction.METHODS The medical records of 120 patients with adhesive intestinal obstruction presenting at Taihe Hospital Affiliated with Hubei Medical College were retrospectively analyzed from January 2022 to January 2024 according to the severity of ultrasound images,divided into simple(mild),complex(moderate),and critical(severe),analyzing the imaging characteristics of patients with different ultrasound classifications,and developing the corresponding treatment plan according to the ultrasound typing results,that is,conservative treatment and surgical treatment,contrast the ultrasound signs of patients in the conservative vs surgical treatment groups,and the value of ultrasound classification in the treatment of adhesive ileus.RESULTS Among the 120 patients,P>0.05,compared with the general data(sex,age,body quality index,time to onset,and history of onset),the proportion of bowel distension and abdominal effusion(P>0.05),and the proportion of adhesion mass and cross-cross in the conservative treatment group,P<0.05.CONCLUSION Ultrasound typing can aid in the clinical evaluation of the severity of adhesive intestinal obstruction and provide an imaging reference for clinicians to develop targeted treatment plans.
文摘Rationale:Advances in sleep research have introduced medications like lemborexant,a dual orexin receptor antagonist.While effective for regulating sleep,overdoses are a concern,especially in suicide attempts.However,limited data exist on lemborexant overdose,prompting this case report to elucidate its clinical course.Patient’s Concern:A 91-year-old Japanese woman with multiple comorbidities,including insomnia and chronic kidney disease,was admitted after ingesting 315 mg of lemborexant in a suicide attempt.Diagnosis:Lemborexant overdose.Interventions:Supportive care with 500 mL of Ringer’s acetate solution at the emergency room.Outcomes:She gradually regained full consciousness with no residual deficits.Due to persistent suicidal ideation,she was transferred to a psychiatric hospital after seven days of supportive care.Lessons:A review of four lemborexant overdose cases managed at our hospital revealed that overdoses primarily induce altered consciousness and are unlikely to cause organ dysfunction.Supportive care is generally sufficient for management.However,given the limited data,further case accumulation is needed to enhance clinical understanding.
文摘This paper investigates a wireless powered communication network(WPCN)facilitated by an unmanned aerial vehicle(UAV)in Internet of Things(IoT)networks,where multiple IoT devices(IoTDs)gather energy from a terrestrial energy station(ES)during the wireless energy transfer(WET)stage,followed by the UAV collecting data from these powered IoTDs with the time division multiple access(TDMA)protocol in the wireless information transfer(WIT)stage.To overcome the challenges of radio propagation caused by obstructions,we incorporate a reconfigurable intelligent surface(RIS)to enhance the link quality of the ES-IoTDs and IoTDs-UAV.The primary objective is to maximize the average sum rate of all IoTDs by jointly optimizing UAV trajectory,ES transmit power,and RIS phase shifts,along with the time allocation for WET and WIT.To this end,we reformulate the optimization problem as a markov decision process(MDP)and introduce a deep reinforcement learning(DRL)approach for addressing the formulated problem,called the proximal policy optimization(PPO)based energy harvesting with trajectory design and phase shift optimization(PPO-EHTDPS)algorithm.By continuously exploring within the environment,the PPO algorithm refines its policy to optimize the UAV trajectory,the energy phase shifts,ES transmit power,and WET/WIT time allocation.Additionally,a continuous phase shift optimization algorithm is employed to determine the information phase shifts for each IoTD to maximize average sum rate.Finally,numerical results demonstrate that the proposed PPOEHTDPS algorithm can significantly achieve higher average sum rate and show better convergence performance over the benchmark algorithms.
基金funded by the Research Organization for Agricultural and Food,the National Research and Innovation Agency(BRIN),and Universitas Gadjah Mada.
文摘Rice,as a primary commodity,needs to be increased in production while facing the sustainability challenges of limited land,water resources,and climate change.The demand for rice productivity was not enough to rely only on the fertile fields’ability;it is necessary to consider the rainfed land potential.Cultivation in rainfed land involves biophysical pressure,lowproduction,and limited access to superior varieties.Participatory rice breeding aimed to identify farmers’trait preferences and develop acceptable lines.A bottom-up approach involved 203 farmers from four rainfed fields in Indonesia,i.e.,Semarang-Central Java,Kulon Progo-Yogyakarta,Tabanan-Bali,andGunungkidul-Yogyakarta.The experiment on February-June 2024 tested six lines(G2,G3,G4,G5,G9,and G10)and four varieties(Situ Bagendit,Gamagora7,Inpari IRNutri Zinc,and Inpago12 Agritan).Farmers’involvement in evaluating the suitability of genotypes involved using Multidimensional Scaling and Importance-Performance Analysis.Breeders added comprehensive analysis in the growing environment with Genotype Environment Interaction,and key attributes of leverage analysis from farmers must be considered.Genotype performance in the Multidimensional Scaling feasibility indicated that yield primary determinants were panicle type,disease resistance,leaf characteristics,and environmental resilience.Importance Performance Analysis verified that G3,G9,G2,and G4 had a preference at the farm level.Genotype Environment Interaction reveals that G3,G4,and G2 were ideal lines with high potential yields,suitability,and adaptability on rainfed land.Participatory rice breeding in rainfed land integrates farmers’assessments and breeders’observations to realize the most preferred genotypes according to the challenges for sustainable agriculture.
基金supported by the funded project(HYZHX M05005)in the field of space medical experiments of manned spaceflight engineering.
文摘Objective:To evaluate the efficacy and safety of transcutaneous electrical acupoint stimulation(TEAS)for muscle atrophy in patients with immobilization after surgical fixation of foot and ankle fractures.Methods:This was a two-arm randomized controlled trial wherein 80 patients were recruited and divided into control(n=40)and intervention(n=40)groups.The control group received conventional orthopedic treatment,whereas the intervention group received TEAS and conventional treatment.The intervention group received TEAS 3 times a week for 30 min each time for 8 weeks.The primary out-comes were muscle thickness(MT)and cross-sectional area(CSA)of the rectus femoris and gastroc-nemius muscles,whereas the secondary outcome measure was echo intensity(EI).Data were collected before the fixation operations(baseline assessment)and 4 and 8 weeks after intervention.Results:Compared with baseline,the MT and CSA were reduced in both groups by the end of treatment,whereas EI increased in both groups.At week 4,the reduction in the rectus femoris CSA in the inter-vention group was significantly lower than that in the control group(P=0.02);however,the between-group differences in the MT and EI(all P>0.05)were not significant.No serious adverse events were observed in either group.Conclusion:Our study showed that TEAS can improve muscle atrophy by attenuating the decline in the muscle CSA.Because this was only a pilot trial,subsequent studies will need longer follow-ups and larger sample sizes.
文摘The increasing challenges of environmental degradation,soil erosion,and climate change have driven interest in sustainable solutions like enhanced weathering(EW)and phytoremediation.Elephant Grass(Cenchrus purpureus),a fast-growing perennial species,shows promise as a bioaccumulator and agent for soil weathering.This study assessed the potential of C.purpureus to improve soil quality through heavy metal(HM)uptake and EW facilitation.A 60-day greenhouse pot experiment at Jackson State University evaluated plant performance in soils amended with metabasalt rock powder at 1:1 and 2:1 rock-to-soil ratios.Biomass,growth,and HM concentrations in roots and shoots were measured via ICP-MS after wet digestion.Soil pH and magnesium(Mg)release were also monitored to assess weathering and carbon drawdown.Results showed that C.purpureus accumulated more HMs in roots at higher amendment levels,while at lower levels,metals like As,Cd,and Cr were more translocated to shoots,enhancing phytoextraction potential.High treatment favored Fe and Al uptake,possibly reducing toxic metal accumulation in edible parts.Notably,C.purpureus contributed to the weathering of 38%of metabasalt rock,leading to a 42%increase in Mg release.With high biomass,HM tolerance,and weathering capacity,C.purpureus offers a sustainable strategy for soil remediation,improved soil health,and potential support for renewable energy systems.
