Fine-grained sedimentary rocks have become a research focus as important reservoirs and source rocks for tight and shale oil and gas.Laminae development determines the accumulation and production of tight and shale oi...Fine-grained sedimentary rocks have become a research focus as important reservoirs and source rocks for tight and shale oil and gas.Laminae development determines the accumulation and production of tight and shale oil and gas in fine-grained rocks.However,due to the resolution limit of conventional logs,it is challenging to recognize the features of centimeter-scale laminae.To close this gap,complementary studies,including core observation,thin section,X-ray diffraction(XRD),conventional log analysis,and slabs of image logs,were conducted to unravel the centimeter-scale laminae.The laminae recognition models were built using well logs.The fine-grained rocks can be divided into laminated rocks(lamina thickness of<0.01 m),layered rocks(0.01-0.1 m),and massive rocks(no layer or layer spacing of>0.1 m)according to the laminae scale from core observations.According to the mineral superposition assemblages from thin-section observations,the laminated rocks can be further divided into binary,ternary,and multiple structures.The typical mineral components,slabs,and T2spectrum distributions of various lamina types are unraveled.The core can identify the centimeter-millimeter-scale laminae,and the thin section can identify the millimeter-micrometer-scale laminae.Furthermore,they can detect mineral types and their superposition sequence.Conventional logs can identify the meter-scale layers,whereas image logs and related slabs can identify the laminae variations at millimeter-centimeter scales.Therefore,the slab of image logs combined with thin sections can identify laminae assemblage characteristics,including the thickness and vertical assemblage.The identification and classification of lamina structure of various scales on a single well can be predicted using conventional logs,image logs,and slabs combined with thin sections.The layered rocks have better reservoir quality and oil-bearing potential than the massive and laminated rocks.The laminated rocks’binary lamina is better than the ternary and multiple layers due to the high content of felsic minerals.The abovementioned results build the prediction model for multiscale laminae structure using well logs,helping sweet spots prediction in the Permian Lucaogou Formation in the Jimusar Sag and fine-grained sedimentary rocks worldwide.展开更多
Alcohol liver disease(ALD)has become a global threat to human health.It is associated with a wide range of liver diseases including alcohol fatty liver,steatosis,fibrosis and cirrhosis,and finally leads to liver cance...Alcohol liver disease(ALD)has become a global threat to human health.It is associated with a wide range of liver diseases including alcohol fatty liver,steatosis,fibrosis and cirrhosis,and finally leads to liver cancer and even death.Centranthera grandiflora is a traditional Chinese medicinal herb commonly used to treat ALD,but no research about its mechanism is available.This study evaluated the hepatoprotective effect and mechanism of C.grandiflora against alcohol-induced liver injury in mice.We found that the ethanol extracts of C.grandiflora(CgW)alleviated the alcohol-induced liver injury,enhanced the levels of antioxidant enzymes,and reduced the amount of lipid peroxides.CgW also affected cell apoptosis by inhibiting the activity of Bax,cleaved-caspase 3 and cleaved-caspase 9,and increasing the activity of Bcl-2.In conclusion,the results showed that CgW can effectively improve ALD through alleviating oxidative stress and inhibiting cell apoptosis for the first time.This study suggested that C.grandiflora is a promising herbal medicine for ALD treatment.展开更多
To find out the reason of resulting in the crease recovery of a fabric and provide theoretical guidance for designing a new material with good creasing-recovery property,the relationship between the creasing-recovery ...To find out the reason of resulting in the crease recovery of a fabric and provide theoretical guidance for designing a new material with good creasing-recovery property,the relationship between the creasing-recovery force and the crease-recovery angle of a woven fabric was investigated by self-setup experimental device.The results show that the crease-recovery angle of a woven fabric is correlated with the creasing-recovery force of the fabric in a linear relation.Furthermore,it is found that the internal stress is the principal force of affecting the creasing-recovery property of a woven fabric.In addition,the relationship between the tensile property of a woven fabric and the creasing-recovery property of the fabric has also been investigated,showing that the lower relaxation velocity of tensile stress of a fabric is,the better creasing-recovery property of the fabric has.展开更多
China is building a model project of digital government with the fully digitalized electronic invoices(FDEls)at the core.Through the"unified national e-invoice service platform",online invoice collection,aut...China is building a model project of digital government with the fully digitalized electronic invoices(FDEls)at the core.Through the"unified national e-invoice service platform",online invoice collection,automatic quota allocation and direct connection with enterprises can be achieved,which can reduce cost,enhance efficiency and promote digital transformation of enterprises.Relying on the precise supervision system of"data+rules,which covers hundreds of millions of trusted identity subjects,the platform can prevent and control risks in real time and align with international standards.The reform has achieved remarkable results:it has covered 95%of enterprises across the country,saved over RMB100 billion in costs annually,and reduced 30 billion paper invoices.Breakthrough innovations,including reconstructing the traditional invoice ecosystem,building the largest information technology innovation cloud platform and digital identity system,and promoting the internationalization of independent tax algorithms,have provided the Chinese solution for"data-driven tax governance"to the world,and contributed to high-quality development andhigh-levelopeningup.展开更多
基金National Natural Science Foundation of China(Grant No.42002133,42072150)Science Foundation of China University of Petroleum,Beijing(No.2462021YXZZ003)the Strategic Cooperation Technology Projects of CNPC and CUPB(ZLZX2020-01-06)for the financial supports and permissions to publish this paper
文摘Fine-grained sedimentary rocks have become a research focus as important reservoirs and source rocks for tight and shale oil and gas.Laminae development determines the accumulation and production of tight and shale oil and gas in fine-grained rocks.However,due to the resolution limit of conventional logs,it is challenging to recognize the features of centimeter-scale laminae.To close this gap,complementary studies,including core observation,thin section,X-ray diffraction(XRD),conventional log analysis,and slabs of image logs,were conducted to unravel the centimeter-scale laminae.The laminae recognition models were built using well logs.The fine-grained rocks can be divided into laminated rocks(lamina thickness of<0.01 m),layered rocks(0.01-0.1 m),and massive rocks(no layer or layer spacing of>0.1 m)according to the laminae scale from core observations.According to the mineral superposition assemblages from thin-section observations,the laminated rocks can be further divided into binary,ternary,and multiple structures.The typical mineral components,slabs,and T2spectrum distributions of various lamina types are unraveled.The core can identify the centimeter-millimeter-scale laminae,and the thin section can identify the millimeter-micrometer-scale laminae.Furthermore,they can detect mineral types and their superposition sequence.Conventional logs can identify the meter-scale layers,whereas image logs and related slabs can identify the laminae variations at millimeter-centimeter scales.Therefore,the slab of image logs combined with thin sections can identify laminae assemblage characteristics,including the thickness and vertical assemblage.The identification and classification of lamina structure of various scales on a single well can be predicted using conventional logs,image logs,and slabs combined with thin sections.The layered rocks have better reservoir quality and oil-bearing potential than the massive and laminated rocks.The laminated rocks’binary lamina is better than the ternary and multiple layers due to the high content of felsic minerals.The abovementioned results build the prediction model for multiscale laminae structure using well logs,helping sweet spots prediction in the Permian Lucaogou Formation in the Jimusar Sag and fine-grained sedimentary rocks worldwide.
基金supported by the National Science and Technology Major Projects of New Drugs(Nos.2019ZX09301124,2019ZX09201001 and 2019ZX09301-110)the Project Program of the State Key Laboratory of Natural Medicines(No.SKLNMZZCX201821)+3 种基金the Natural Science Foundation of Jiangsu Province,China(No.BK20180569)the Open Project of State Key Laboratory of Natural Medicines(No.SKLNMKF202008)the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD)and the“Double First-Class”University Project(Nos.CPU2018GY13 and CPU2018PZH03)。
文摘Alcohol liver disease(ALD)has become a global threat to human health.It is associated with a wide range of liver diseases including alcohol fatty liver,steatosis,fibrosis and cirrhosis,and finally leads to liver cancer and even death.Centranthera grandiflora is a traditional Chinese medicinal herb commonly used to treat ALD,but no research about its mechanism is available.This study evaluated the hepatoprotective effect and mechanism of C.grandiflora against alcohol-induced liver injury in mice.We found that the ethanol extracts of C.grandiflora(CgW)alleviated the alcohol-induced liver injury,enhanced the levels of antioxidant enzymes,and reduced the amount of lipid peroxides.CgW also affected cell apoptosis by inhibiting the activity of Bax,cleaved-caspase 3 and cleaved-caspase 9,and increasing the activity of Bcl-2.In conclusion,the results showed that CgW can effectively improve ALD through alleviating oxidative stress and inhibiting cell apoptosis for the first time.This study suggested that C.grandiflora is a promising herbal medicine for ALD treatment.
文摘To find out the reason of resulting in the crease recovery of a fabric and provide theoretical guidance for designing a new material with good creasing-recovery property,the relationship between the creasing-recovery force and the crease-recovery angle of a woven fabric was investigated by self-setup experimental device.The results show that the crease-recovery angle of a woven fabric is correlated with the creasing-recovery force of the fabric in a linear relation.Furthermore,it is found that the internal stress is the principal force of affecting the creasing-recovery property of a woven fabric.In addition,the relationship between the tensile property of a woven fabric and the creasing-recovery property of the fabric has also been investigated,showing that the lower relaxation velocity of tensile stress of a fabric is,the better creasing-recovery property of the fabric has.
文摘China is building a model project of digital government with the fully digitalized electronic invoices(FDEls)at the core.Through the"unified national e-invoice service platform",online invoice collection,automatic quota allocation and direct connection with enterprises can be achieved,which can reduce cost,enhance efficiency and promote digital transformation of enterprises.Relying on the precise supervision system of"data+rules,which covers hundreds of millions of trusted identity subjects,the platform can prevent and control risks in real time and align with international standards.The reform has achieved remarkable results:it has covered 95%of enterprises across the country,saved over RMB100 billion in costs annually,and reduced 30 billion paper invoices.Breakthrough innovations,including reconstructing the traditional invoice ecosystem,building the largest information technology innovation cloud platform and digital identity system,and promoting the internationalization of independent tax algorithms,have provided the Chinese solution for"data-driven tax governance"to the world,and contributed to high-quality development andhigh-levelopeningup.
