Background:With the rapid development of modern emerging technologies,the ethical dilemmas and social controversies triggered by scientific and technological activities have become increasingly prominent.How to guide ...Background:With the rapid development of modern emerging technologies,the ethical dilemmas and social controversies triggered by scientific and technological activities have become increasingly prominent.How to guide technology for good and prevent and control technological risks has become an important issue of global concern.Research on science and technology ethics is dedicated to integrating ethical theories into governance practices and constructing ethical models that adapt to the development of the times.Methods:This article systematically reviews the six core approaches of scientific and technological ethics thought,including technological autonomy and political philosophy criticism,responsibility ethics and intergenerational obligations,technological intermediation and the integration of life and the world,ethical principles and normative frameworks,participatory governance and ethical practice innovation,as well as domain-specific ethical norms,thereby constructing an ethical analysis framework applicable to medical technology risks.And cross-analysis was conducted by taking medical events such as gene editing and xenotransplantation as examples.Results:Research shows that a single ethical approach has limitations in addressing complex medical ethical challenges,while the six approaches are complementary and synergistic.By criticizing technological autonomy,establishing a responsibility ethics orientation,setting the bottom line of ethical principles,promoting participatory governance,formulating domain norms,and continuously reflecting on the intermediary nature of technology,a multi-level and dynamically adaptive governance system for scientific and technological ethics can be constructed.Conclusion:The key to addressing contemporary medical ethics challenges lies in the comprehensive application of science and technology ethics theories and the integration of ethical considerations throughout the entire process of scientific and technological research and development.In the future,a governance framework that adapts to the development of new technologies should be established to promote cross-cultural and cross-disciplinary ethical dialogue and public participation,ensuring that scientific and technological innovation always serves the dignity of human life and overall well-being.展开更多
Nanotechnology has revolutionized drug delivery,particularly through nanoformulations of phytoconstituents,enhancing their therapeutic potential.Despite their broad bioactivities,plant-based compounds often suffer fro...Nanotechnology has revolutionized drug delivery,particularly through nanoformulations of phytoconstituents,enhancing their therapeutic potential.Despite their broad bioactivities,plant-based compounds often suffer from poor bioavailability and stability.Nanoformulations address these limitations by improving solubility,targeted delivery,and controlled release.This approach opens new possibilities for treating chronic diseases like cancer,diabetes,and neurodegenerative disorders.This review aims to examine recent advancements in nanotechnology-based formulation strategies designed to enhance the delivery,stability,and therapeutic efficacy of phytochemicals and also discusses regulatory issues,safety concerns,scalability,and cost-effectiveness.Emphasis was placed on nanoformulation techniques employed for key phytoconstituents such as curcumin,resveratrol,epigallocatechin gallate,and quercetin.The most commonly employed nanocarriers included polymeric nanoparticles,solid lipid nanoparticles,and liposomes.These formulations significantly improved the solubility,stability,and controlled release profiles of phytochemicals.In vitro and in vivo studies demonstrated enhanced anti-inflammatory,anticancer,and antioxidant activities.Moreover,surface-modified and targeted nanoparticles showed promise in increasing site-specific targeting and enhancing bioavailability of the encapsulated compounds.Nanoformulations present a promising strategy for overcoming the pharmacokinetic limitations of phytochemicals.Despite encouraging preclinical results,further studies are needed to address issues related to long-term safety,clinical efficacy,and regulatory approval for successful clinical translation.展开更多
Neural machine interface technology is a pioneering approach that aims to address the complex challenges of neurological dysfunctions and disabilities resulting from conditions such as congenital disorders,traumatic i...Neural machine interface technology is a pioneering approach that aims to address the complex challenges of neurological dysfunctions and disabilities resulting from conditions such as congenital disorders,traumatic injuries,and neurological diseases.Neural machine interface technology establishes direct connections with the brain or peripheral nervous system to restore impaired motor,sensory,and cognitive functions,significantly improving patients'quality of life.This review analyzes the chronological development and integration of various neural machine interface technologies,including regenerative peripheral nerve interfaces,targeted muscle and sensory reinnervation,agonist–antagonist myoneural interfaces,and brain–machine interfaces.Recent advancements in flexible electronics and bioengineering have led to the development of more biocompatible and highresolution electrodes,which enhance the performance and longevity of neural machine interface technology.However,significant challenges remain,such as signal interference,fibrous tissue encapsulation,and the need for precise anatomical localization and reconstruction.The integration of advanced signal processing algorithms,particularly those utilizing artificial intelligence and machine learning,has the potential to improve the accuracy and reliability of neural signal interpretation,which will make neural machine interface technologies more intuitive and effective.These technologies have broad,impactful clinical applications,ranging from motor restoration and sensory feedback in prosthetics to neurological disorder treatment and neurorehabilitation.This review suggests that multidisciplinary collaboration will play a critical role in advancing neural machine interface technologies by combining insights from biomedical engineering,clinical surgery,and neuroengineering to develop more sophisticated and reliable interfaces.By addressing existing limitations and exploring new technological frontiers,neural machine interface technologies have the potential to revolutionize neuroprosthetics and neurorehabilitation,promising enhanced mobility,independence,and quality of life for individuals with neurological impairments.By leveraging detailed anatomical knowledge and integrating cutting-edge neuroengineering principles,researchers and clinicians can push the boundaries of what is possible and create increasingly sophisticated and long-lasting prosthetic devices that provide sustained benefits for users.展开更多
The mechanisms underlying the pathophysiology of ischemic stroke are complex and multifactorial and include excitotoxicity,oxidative stress,inflammatory responses,and blood–brain barrier disruption.While vascular rec...The mechanisms underlying the pathophysiology of ischemic stroke are complex and multifactorial and include excitotoxicity,oxidative stress,inflammatory responses,and blood–brain barrier disruption.While vascular recanalization treatments such as thrombolysis and mechanical thrombectomy have achieved some success,reperfusion injury remains a significant contributor to the exacerbation of brain injury.This emphasizes the need for developing neuroprotective strategies to mitigate this type of injury.The purpose of this review was to examine the application of nanotechnology in the treatment of ischemic stroke,covering research progress in nanoparticlebased drug delivery,targeted therapy,and antioxidant and anti-inflammatory applications.Nanobased drug delivery systems offer several advantages compared to traditional therapies,including enhanced blood–brain barrier penetration,prolonged drug circulation time,improved drug stability,and targeted delivery.For example,inorganic nanoparticles,such as those based on CeO_(2),have been widely studied for their strong antioxidant capabilities.Biomimetic nanoparticles,such as those coated with cell membranes,have garnered significant attention owing to their excellent biocompatibility and targeting abilities.Nanoparticles can be used to deliver a wide range of neuroprotective agents,such as antioxidants(e.g.,edaravone),anti-inflammatory drugs(e.g.,curcumin),and neurotrophic factors.Nanotechnology significantly enhances the efficacy of these drugs while minimizing adverse reactions.Although nanotechnology has demonstrated great potential in animal studies,its clinical application still faces several challenges,including the long-term safety of nanoparticles,the feasibility of large-scale production,quality control,and the ability to predict therapeutic effects in humans.In summary,nanotechnology holds significant promise for the treatment of ischemic stroke.Future research should focus on further exploring the mechanisms of action of nanoparticles,developing multifunctional nanoparticles,and validating their safety and efficacy through rigorous clinical trials.Moreover,interdisciplinary collaboration is essential for advancing the use of nanotechnology in stroke treatment.展开更多
Subgrade engineering is a fundamental aspect of infrastructure construction in China.As the primary structural element responsible for bearing and distributing traffic loads,the subgrade must not only withstand the su...Subgrade engineering is a fundamental aspect of infrastructure construction in China.As the primary structural element responsible for bearing and distributing traffic loads,the subgrade must not only withstand the substantial pressures exerted by vehicles,trains,and other forms of transportation,but also efficiently transfer these loads to the underlying foundation,ensuring the stability and longevity of the roadway.In recent years,advancements in subgrade engineering technology have propelled the industry towards smarter,greener,and more sustainable practices,particularly in the areas of intelligent monitoring,disaster management,and innovative construction methods.This paper reviews the application and methodologies of intelligent testing equipment,including cone penetration testing(CPT)devices,soil resistivity testers,and intelligent rebound testers,in subgrade engineering.It examines the operating principles,advantages,limitations,and application ranges of these tools in subgrade testing.Additionally,the paper evaluates the practical use of advanced equipment from both domestic and international perspectives,addressing the challenges encountered by various instruments in realworld applications.These devices enable precise,comprehensive testing and evaluation of subgrade conditions at different stages,providing real-time data analysis and intelligent early warnings.This supports effective subgrade health management and maintenance.As intelligent technologies continue to evolve and integrate,these tools will increasingly enhance the accuracy,efficiency,and sustainability of subgrade monitoring.展开更多
This article focuses on the current computer monitoring and control as the research direction,studying the application strategies of artificial intelligence and big data technology in this field.It includes an introdu...This article focuses on the current computer monitoring and control as the research direction,studying the application strategies of artificial intelligence and big data technology in this field.It includes an introduction to artificial intelligence and big data technology,the application strategies of artificial intelligence and big data technology in computer hardware,software,and network monitoring,as well as the application strategies of artificial intelligence and big data technology in computer process,access,and network control.This analysis aims to serve as a reference for the application of artificial intelligence and big data technology in computer monitoring and control,ultimately enhancing the security of computer systems.展开更多
With the acceleration of the intelligent transformation of power systems,the requirements for communication technology are increasingly stringent.The application of 5G mobile communication technology in power communic...With the acceleration of the intelligent transformation of power systems,the requirements for communication technology are increasingly stringent.The application of 5G mobile communication technology in power communication is analyzed.In this study,5G technology features,application principles,and practical strategies are discussed,and methods such as network slicing,customized deployment,edge computing collaborative application,communication equipment integration and upgrading,and multi-technology collaboration and complementation are proposed.It aims to effectively improve the efficiency,reliability,and security of power communication,solve the problem that traditional communication technology is difficult to meet the diversified needs of power business,and achieve the effect of optimizing the power communication network and supporting the intelligent development of the power system.展开更多
The software technology field is facing new talent demands brought by the Information Technology Application Innovation(ITAI)industry.This paper takes Shanwei Institute of Technology as an example to deeply explore th...The software technology field is facing new talent demands brought by the Information Technology Application Innovation(ITAI)industry.This paper takes Shanwei Institute of Technology as an example to deeply explore the construction of a school-enterprise community education model driven by the ITAI industry.It establishes the Kirin Workshop training base to facilitate talent cultivation,integrates the ITAI Application Adaptation Center to enhance technical capabilities,cooperates with Liqi Technology to establish an industrial college for government talent training,adjusts the professional curriculum system,and arranges for students to participate in ITAI vocational skills competitions.The school-enterprise collaborative cultivation mechanism meets the talent needs of the ITAI field,with effective practical results.This paper also points out the shortcomings of the school-enterprise collaborative education model in the ITAI industry and provides optimization methods to explore new paths for industry-education integration and serve the development of regional and national ITAI industries^([1]).展开更多
Terahertz biotechnology has been increasingly applied in various biomedical fields and has especially shown great potential for application in brain sciences.In this article,we review the development of terahertz biot...Terahertz biotechnology has been increasingly applied in various biomedical fields and has especially shown great potential for application in brain sciences.In this article,we review the development of terahertz biotechnology and its applications in the field of neuropsychiatry.Available evidence indicates promising prospects for the use of terahertz spectroscopy and terahertz imaging techniques in the diagnosis of amyloid disease,cerebrovascular disease,glioma,psychiatric disease,traumatic brain injury,and myelin deficit.In vitro and animal experiments have also demonstrated the potential therapeutic value of terahertz technology in some neuropsychiatric diseases.Although the precise underlying mechanism of the interactions between terahertz electromagnetic waves and the biosystem is not yet fully understood,the research progress in this field shows great potential for biomedical noninvasive diagnostic and therapeutic applications.However,the biosafety of terahertz radiation requires further exploration regarding its two-sided efficacy in practical applications.This review demonstrates that terahertz biotechnology has the potential to be a promising method in the field of neuropsychiatry based on its unique advantages.展开更多
Purpose–This study summarizes the overall situation of the resources of the national science and technology innovation platform in the railway industry,including the distribution of platform types,supporting institut...Purpose–This study summarizes the overall situation of the resources of the national science and technology innovation platform in the railway industry,including the distribution of platform types,supporting institutions,construction sites,professional fields,etc.,to provide a reference for the further improvement and optimization of the national science and technology innovation platform system in the railway industry.Design/methodology/approach–Through literature review,field investigation,expert consultation and other methods,this paper systematically investigates and analyzes the development status of the national science and technology innovation platform in the railway industry.Findings–Taking the national science and technology innovation platform of the railway industry as the research object,this paper investigates and analyzes the construction,development and distribution of the national science and technology innovation platform of railway industry over the years.And the National Engineering Research Center of High-speed Railway and Urban Rail Transit System Technology was taken as an example to introduce its operation effect.Originality/value–China Railway has made great development achievements,with the construction and development of national science and technology innovation platform in the railway industry.In recent years,a large number of national science and technology innovation platforms have been built in the railway industry,which play an important role in railway technological innovation,standard setting and commodification,and Railway Sciences provide strong support for railway technology development.展开更多
As the core information infrastructure of modern information warfare,the offensive and defensive confrontations of satellite navigation systems have given rise to navigation warfare,which focuses on seizing control of...As the core information infrastructure of modern information warfare,the offensive and defensive confrontations of satellite navigation systems have given rise to navigation warfare,which focuses on seizing control of navigation resources.Based on the space segment,control segment,and user segment of satellite navigation systems,this paper systematically constructs an offensive-defensive technology system for navigation warfare,and deeply analyzes core measures such as signal enhancement and suppression,autonomous navigation and link jamming,anti-jamming reception,and integrated navigation.It extracts key technologies including adaptive nulling antennas,joint filtering,and multi-dimensional combined jamming,and discusses the technical effectiveness of these technologies by incorporating relevant cases.The advantages of navigation warfare stem from multi-segment coordination and technological inte-gration.In the future,the development directions of navigation warfare will focus on three aspects:enhancing satellite capabilities,tackling core technical challenges,and building a multi-dimensional system.展开更多
In this work,the generation of high signal-to-noise ratio(SNR)single-frequency microwave signal without noise sidebands is demonstrated based on the interaction of integrated all-fiber lasers.The microwave signals are...In this work,the generation of high signal-to-noise ratio(SNR)single-frequency microwave signal without noise sidebands is demonstrated based on the interaction of integrated all-fiber lasers.The microwave signals are generated by the interference between a narrow linewidth Brillouin pump light from a single-frequency laser and the Stokes light generated by it.Firstly,the linewidths of the Stokes lights are compressed to~43 Hz based on the stimulated Brillouin scattering(SBS)effect,which ensures that the frequency noise is as low as possible.And then,the relative intensity noise(RIN)of the first order Stokes light is reduced by 21 dB/Hz based on the noise dynamics principle in cascaded SBS effect.By simultaneously reducing the frequency noise and the intensity noise of the coherent signals,the noise sidebands of microwave signals are completely suppressed.As result,the SNR of the microwave signal is improved from 48 dB to 84 dB at the first-order Brillouin frequency shift of 9.415 GHz.Meanwhile,a microwave signal with a SNR of 70 dB is generated at the second-order Brillouin frequency shift of 18.827 GHz.This kind of microwave signals with narrow linewidth and high SNR can provide higher detection resolution and higher transmission efficiency for applications on radar,satellite communication and so on.展开更多
This paper focuses on the preparation of rare earth oxide products from rare earth chloride solutions during the rare earth extraction and separation processes,as well as the recycling of magnesium chloride solutions....This paper focuses on the preparation of rare earth oxide products from rare earth chloride solutions during the rare earth extraction and separation processes,as well as the recycling of magnesium chloride solutions.It proposes the idea of introducing spray pyrolysis technology into the rare earth extraction and separation processes.This paper briefly describes the development history of chloride spray pyrolysis technology,focusing on the research status and application progress of rare earth chloride solution and magnesium chloride solution spray pyrolysis technology,as well as spray pyrolysis equipment.The paper also analyzes the challenges and technical intricacies associated with applying spray pyrolysis technology to chloride solutions in the rare earth extraction and separation processes.Additionally,it explores future trends and proposes strategies to facilitate the full recycling of acids and bases,streamline the process flow,and enhance the prospects for green and low-carbon rare earth metallurgy.展开更多
This article aims to provide a comprehensive analysis of the role and development prospects of direct satellite-to-phone technology in the global communication landscape.It explores the importance,current development ...This article aims to provide a comprehensive analysis of the role and development prospects of direct satellite-to-phone technology in the global communication landscape.It explores the importance,current development status,key technical challenges,future directions,and countermeasures of this technology from multiple dimensions.The article explains the significance and necessity of direct satellite-to-phone technology in the global communication field,discusses its development background and importance as one of the key technologies in the 6G era,and outlines the research objectives,methodology,and structure of the paper.Additionally,the article reviews and analyzes the development history of direct satellite-to-phone technology on a global scale,discusses the key technical points in achieving this technology,and predicts its potential role and development direction in future communication systems from the perspective of 6G network architecture.It also explores new application scenarios and service models that may emerge from technological advancements,as well as their impact on future communication networks.The development history of direct satellite-to-phone technology and its role in current and future communication networks are emphasized,highlighting its value in promoting global communication infrastructure construction.The article also proposes improvement suggestions for existing issues and points out future research directions.展开更多
This paper focuses on the key issues of tool wear condition monitoring in the field of machining,and deeply discusses the application of digital twin technology in this aspect.This paper expounds the principle and arc...This paper focuses on the key issues of tool wear condition monitoring in the field of machining,and deeply discusses the application of digital twin technology in this aspect.This paper expounds the principle and architecture of digital twin technology,analyzes its specific methods in tool wear data acquisition,modeling,simulation,and real-time monitoring,and shows the significant advantages of this technology in improving the accuracy of tool wear monitoring and realizing predictive maintenance.At the same time,the challenges faced by digital twin technology in tool wear condition monitoring are discussed,and the corresponding development direction is put forward,aiming to provide theoretical reference and practical guidance for optimizing tool management by digital twin technology in the machining industry.展开更多
This paper focuses on the application of artificial intelligence(AI)technology in the reform of college English teaching.By analyzing the current situation of college English teaching and the advantages of AI technolo...This paper focuses on the application of artificial intelligence(AI)technology in the reform of college English teaching.By analyzing the current situation of college English teaching and the advantages of AI technology,it explores how AI technology can be applied in different aspects of college English teaching,such as teaching content delivery,language practice,and assessment.It also discusses the challenges and opportunities brought by AI technology in the teaching reform process and proposes corresponding construction strategies to promote the deep integration of AI technology and college English teaching,aiming to improve the quality and efficiency of college English teaching and develop students’comprehensive English application ability.展开更多
With the continuous development of science and technology,we have already entered the digital age.While big data,artificial intelligence,and digital twin technology provide convenience for various fields of people’s ...With the continuous development of science and technology,we have already entered the digital age.While big data,artificial intelligence,and digital twin technology provide convenience for various fields of people’s lives,they also bring new opportunities for the innovation and development of competitive cheerleading.Especially for the training of aerial techniques in competitive cheerleading,which has high requirements for accuracy,coordination,and safety,the traditional training model has problems such as empiricism and insufficient risk prediction,which directly affect the quality of training.This article discusses the application value and application countermeasures of digital twin technology in the aerial techniques of competitive cheerleading,hoping to provide some reference for relevant personnel.展开更多
The treatment of POME related contamination is complicated due to its high organic contents and complex composition.Membrane technology is a prominent method for removing POME contaminants on account of its efficiency...The treatment of POME related contamination is complicated due to its high organic contents and complex composition.Membrane technology is a prominent method for removing POME contaminants on account of its efficiency in removing suspended particles,organic substances,and contaminants from wastewater,leading to the production of high-quality treated effluent.It is crucial to achieve efficient POME treatment with minimum fouling through membrane advancement to ensure the sustainability for large-scale applications.This article comprehensively analyses the latest advancements in membrane technology for the treatment of POME.A wide range of membrane types including forward osmosis,microfiltration,ultrafiltration,nanofiltration,reverse osmosis,membrane bioreactor,photocatalytic membrane reactor,and their combinations is discussed in terms of the innovative design,treatment efficiencies and antifouling properties.The strategies for antifouling membranes such as self-healing and self-cleaning membranes are discussed.In addition to discussing the obstacles that impede the broad implementation of novel membrane tech nologies in POME treatment,the article concludes by delineating potential avenues for future research and policy considerations.The understanding and insights are expected to enhance the application ofmembrane-basedmethods in order to treat POME more efficiently;this will be instrumental in the reduction of environmental pollution.展开更多
基金supported by the National Key Research and Development Program(Grant No.2024YFA0917200)the Projects of the Chinese Center for Disease Control and Prevention(Grant No.BB2110240093)World Medical History under the Education Innovation Plan of the University of Science and Technology of China(Grant No.2024YCHX07).
文摘Background:With the rapid development of modern emerging technologies,the ethical dilemmas and social controversies triggered by scientific and technological activities have become increasingly prominent.How to guide technology for good and prevent and control technological risks has become an important issue of global concern.Research on science and technology ethics is dedicated to integrating ethical theories into governance practices and constructing ethical models that adapt to the development of the times.Methods:This article systematically reviews the six core approaches of scientific and technological ethics thought,including technological autonomy and political philosophy criticism,responsibility ethics and intergenerational obligations,technological intermediation and the integration of life and the world,ethical principles and normative frameworks,participatory governance and ethical practice innovation,as well as domain-specific ethical norms,thereby constructing an ethical analysis framework applicable to medical technology risks.And cross-analysis was conducted by taking medical events such as gene editing and xenotransplantation as examples.Results:Research shows that a single ethical approach has limitations in addressing complex medical ethical challenges,while the six approaches are complementary and synergistic.By criticizing technological autonomy,establishing a responsibility ethics orientation,setting the bottom line of ethical principles,promoting participatory governance,formulating domain norms,and continuously reflecting on the intermediary nature of technology,a multi-level and dynamically adaptive governance system for scientific and technological ethics can be constructed.Conclusion:The key to addressing contemporary medical ethics challenges lies in the comprehensive application of science and technology ethics theories and the integration of ethical considerations throughout the entire process of scientific and technological research and development.In the future,a governance framework that adapts to the development of new technologies should be established to promote cross-cultural and cross-disciplinary ethical dialogue and public participation,ensuring that scientific and technological innovation always serves the dignity of human life and overall well-being.
文摘Nanotechnology has revolutionized drug delivery,particularly through nanoformulations of phytoconstituents,enhancing their therapeutic potential.Despite their broad bioactivities,plant-based compounds often suffer from poor bioavailability and stability.Nanoformulations address these limitations by improving solubility,targeted delivery,and controlled release.This approach opens new possibilities for treating chronic diseases like cancer,diabetes,and neurodegenerative disorders.This review aims to examine recent advancements in nanotechnology-based formulation strategies designed to enhance the delivery,stability,and therapeutic efficacy of phytochemicals and also discusses regulatory issues,safety concerns,scalability,and cost-effectiveness.Emphasis was placed on nanoformulation techniques employed for key phytoconstituents such as curcumin,resveratrol,epigallocatechin gallate,and quercetin.The most commonly employed nanocarriers included polymeric nanoparticles,solid lipid nanoparticles,and liposomes.These formulations significantly improved the solubility,stability,and controlled release profiles of phytochemicals.In vitro and in vivo studies demonstrated enhanced anti-inflammatory,anticancer,and antioxidant activities.Moreover,surface-modified and targeted nanoparticles showed promise in increasing site-specific targeting and enhancing bioavailability of the encapsulated compounds.Nanoformulations present a promising strategy for overcoming the pharmacokinetic limitations of phytochemicals.Despite encouraging preclinical results,further studies are needed to address issues related to long-term safety,clinical efficacy,and regulatory approval for successful clinical translation.
基金supported in part by the National Natural Science Foundation of China,Nos.81927804(to GL),82260456(to LY),U21A20479(to LY)Science and Technology Planning Project of Shenzhen,No.JCYJ20230807140559047(to LY)+3 种基金Key-Area Research and Development Program of Guangdong Province,No.2020B0909020004(to GL)Guangdong Basic and Applied Research Foundation,No.2023A1515011478(to LY)the Science and Technology Program of Guangdong Province,No.2022A0505090007(to GL)Ministry of Science and Technology,Shenzhen,No.QN2022032013L(to LY)。
文摘Neural machine interface technology is a pioneering approach that aims to address the complex challenges of neurological dysfunctions and disabilities resulting from conditions such as congenital disorders,traumatic injuries,and neurological diseases.Neural machine interface technology establishes direct connections with the brain or peripheral nervous system to restore impaired motor,sensory,and cognitive functions,significantly improving patients'quality of life.This review analyzes the chronological development and integration of various neural machine interface technologies,including regenerative peripheral nerve interfaces,targeted muscle and sensory reinnervation,agonist–antagonist myoneural interfaces,and brain–machine interfaces.Recent advancements in flexible electronics and bioengineering have led to the development of more biocompatible and highresolution electrodes,which enhance the performance and longevity of neural machine interface technology.However,significant challenges remain,such as signal interference,fibrous tissue encapsulation,and the need for precise anatomical localization and reconstruction.The integration of advanced signal processing algorithms,particularly those utilizing artificial intelligence and machine learning,has the potential to improve the accuracy and reliability of neural signal interpretation,which will make neural machine interface technologies more intuitive and effective.These technologies have broad,impactful clinical applications,ranging from motor restoration and sensory feedback in prosthetics to neurological disorder treatment and neurorehabilitation.This review suggests that multidisciplinary collaboration will play a critical role in advancing neural machine interface technologies by combining insights from biomedical engineering,clinical surgery,and neuroengineering to develop more sophisticated and reliable interfaces.By addressing existing limitations and exploring new technological frontiers,neural machine interface technologies have the potential to revolutionize neuroprosthetics and neurorehabilitation,promising enhanced mobility,independence,and quality of life for individuals with neurological impairments.By leveraging detailed anatomical knowledge and integrating cutting-edge neuroengineering principles,researchers and clinicians can push the boundaries of what is possible and create increasingly sophisticated and long-lasting prosthetic devices that provide sustained benefits for users.
基金supported by the National Natural Science Foundation of China,Nos.82301093(to QC)and 22334004(to HY)the Fuzhou University Fund for Testing Precious Equipment,No.2025T038(to QC)。
文摘The mechanisms underlying the pathophysiology of ischemic stroke are complex and multifactorial and include excitotoxicity,oxidative stress,inflammatory responses,and blood–brain barrier disruption.While vascular recanalization treatments such as thrombolysis and mechanical thrombectomy have achieved some success,reperfusion injury remains a significant contributor to the exacerbation of brain injury.This emphasizes the need for developing neuroprotective strategies to mitigate this type of injury.The purpose of this review was to examine the application of nanotechnology in the treatment of ischemic stroke,covering research progress in nanoparticlebased drug delivery,targeted therapy,and antioxidant and anti-inflammatory applications.Nanobased drug delivery systems offer several advantages compared to traditional therapies,including enhanced blood–brain barrier penetration,prolonged drug circulation time,improved drug stability,and targeted delivery.For example,inorganic nanoparticles,such as those based on CeO_(2),have been widely studied for their strong antioxidant capabilities.Biomimetic nanoparticles,such as those coated with cell membranes,have garnered significant attention owing to their excellent biocompatibility and targeting abilities.Nanoparticles can be used to deliver a wide range of neuroprotective agents,such as antioxidants(e.g.,edaravone),anti-inflammatory drugs(e.g.,curcumin),and neurotrophic factors.Nanotechnology significantly enhances the efficacy of these drugs while minimizing adverse reactions.Although nanotechnology has demonstrated great potential in animal studies,its clinical application still faces several challenges,including the long-term safety of nanoparticles,the feasibility of large-scale production,quality control,and the ability to predict therapeutic effects in humans.In summary,nanotechnology holds significant promise for the treatment of ischemic stroke.Future research should focus on further exploring the mechanisms of action of nanoparticles,developing multifunctional nanoparticles,and validating their safety and efficacy through rigorous clinical trials.Moreover,interdisciplinary collaboration is essential for advancing the use of nanotechnology in stroke treatment.
基金supported by the National Natural Science Foundation of China for Distinguished Young Scholars(Grant No.42225206)National Natural Science Foundation of China(42207180,42477209,42302320).
文摘Subgrade engineering is a fundamental aspect of infrastructure construction in China.As the primary structural element responsible for bearing and distributing traffic loads,the subgrade must not only withstand the substantial pressures exerted by vehicles,trains,and other forms of transportation,but also efficiently transfer these loads to the underlying foundation,ensuring the stability and longevity of the roadway.In recent years,advancements in subgrade engineering technology have propelled the industry towards smarter,greener,and more sustainable practices,particularly in the areas of intelligent monitoring,disaster management,and innovative construction methods.This paper reviews the application and methodologies of intelligent testing equipment,including cone penetration testing(CPT)devices,soil resistivity testers,and intelligent rebound testers,in subgrade engineering.It examines the operating principles,advantages,limitations,and application ranges of these tools in subgrade testing.Additionally,the paper evaluates the practical use of advanced equipment from both domestic and international perspectives,addressing the challenges encountered by various instruments in realworld applications.These devices enable precise,comprehensive testing and evaluation of subgrade conditions at different stages,providing real-time data analysis and intelligent early warnings.This supports effective subgrade health management and maintenance.As intelligent technologies continue to evolve and integrate,these tools will increasingly enhance the accuracy,efficiency,and sustainability of subgrade monitoring.
文摘This article focuses on the current computer monitoring and control as the research direction,studying the application strategies of artificial intelligence and big data technology in this field.It includes an introduction to artificial intelligence and big data technology,the application strategies of artificial intelligence and big data technology in computer hardware,software,and network monitoring,as well as the application strategies of artificial intelligence and big data technology in computer process,access,and network control.This analysis aims to serve as a reference for the application of artificial intelligence and big data technology in computer monitoring and control,ultimately enhancing the security of computer systems.
文摘With the acceleration of the intelligent transformation of power systems,the requirements for communication technology are increasingly stringent.The application of 5G mobile communication technology in power communication is analyzed.In this study,5G technology features,application principles,and practical strategies are discussed,and methods such as network slicing,customized deployment,edge computing collaborative application,communication equipment integration and upgrading,and multi-technology collaboration and complementation are proposed.It aims to effectively improve the efficiency,reliability,and security of power communication,solve the problem that traditional communication technology is difficult to meet the diversified needs of power business,and achieve the effect of optimizing the power communication network and supporting the intelligent development of the power system.
基金supported by the Foundation of Shanwei Institute of Technology(swjy23-008).
文摘The software technology field is facing new talent demands brought by the Information Technology Application Innovation(ITAI)industry.This paper takes Shanwei Institute of Technology as an example to deeply explore the construction of a school-enterprise community education model driven by the ITAI industry.It establishes the Kirin Workshop training base to facilitate talent cultivation,integrates the ITAI Application Adaptation Center to enhance technical capabilities,cooperates with Liqi Technology to establish an industrial college for government talent training,adjusts the professional curriculum system,and arranges for students to participate in ITAI vocational skills competitions.The school-enterprise collaborative cultivation mechanism meets the talent needs of the ITAI field,with effective practical results.This paper also points out the shortcomings of the school-enterprise collaborative education model in the ITAI industry and provides optimization methods to explore new paths for industry-education integration and serve the development of regional and national ITAI industries^([1]).
基金supported by grants from the National Key R&D Program of China,No.2017YFC0909200(to DC)the National Natural Science Foundation of China,No.62075225(to HZ)+1 种基金Zhejiang Provincial Medical Health Science and Technology Project,No.2023XY053(to ZP)Zhejiang Provincial Traditional Chinese Medical Science and Technology Project,No.2023ZL703(to ZP).
文摘Terahertz biotechnology has been increasingly applied in various biomedical fields and has especially shown great potential for application in brain sciences.In this article,we review the development of terahertz biotechnology and its applications in the field of neuropsychiatry.Available evidence indicates promising prospects for the use of terahertz spectroscopy and terahertz imaging techniques in the diagnosis of amyloid disease,cerebrovascular disease,glioma,psychiatric disease,traumatic brain injury,and myelin deficit.In vitro and animal experiments have also demonstrated the potential therapeutic value of terahertz technology in some neuropsychiatric diseases.Although the precise underlying mechanism of the interactions between terahertz electromagnetic waves and the biosystem is not yet fully understood,the research progress in this field shows great potential for biomedical noninvasive diagnostic and therapeutic applications.However,the biosafety of terahertz radiation requires further exploration regarding its two-sided efficacy in practical applications.This review demonstrates that terahertz biotechnology has the potential to be a promising method in the field of neuropsychiatry based on its unique advantages.
文摘Purpose–This study summarizes the overall situation of the resources of the national science and technology innovation platform in the railway industry,including the distribution of platform types,supporting institutions,construction sites,professional fields,etc.,to provide a reference for the further improvement and optimization of the national science and technology innovation platform system in the railway industry.Design/methodology/approach–Through literature review,field investigation,expert consultation and other methods,this paper systematically investigates and analyzes the development status of the national science and technology innovation platform in the railway industry.Findings–Taking the national science and technology innovation platform of the railway industry as the research object,this paper investigates and analyzes the construction,development and distribution of the national science and technology innovation platform of railway industry over the years.And the National Engineering Research Center of High-speed Railway and Urban Rail Transit System Technology was taken as an example to introduce its operation effect.Originality/value–China Railway has made great development achievements,with the construction and development of national science and technology innovation platform in the railway industry.In recent years,a large number of national science and technology innovation platforms have been built in the railway industry,which play an important role in railway technological innovation,standard setting and commodification,and Railway Sciences provide strong support for railway technology development.
文摘As the core information infrastructure of modern information warfare,the offensive and defensive confrontations of satellite navigation systems have given rise to navigation warfare,which focuses on seizing control of navigation resources.Based on the space segment,control segment,and user segment of satellite navigation systems,this paper systematically constructs an offensive-defensive technology system for navigation warfare,and deeply analyzes core measures such as signal enhancement and suppression,autonomous navigation and link jamming,anti-jamming reception,and integrated navigation.It extracts key technologies including adaptive nulling antennas,joint filtering,and multi-dimensional combined jamming,and discusses the technical effectiveness of these technologies by incorporating relevant cases.The advantages of navigation warfare stem from multi-segment coordination and technological inte-gration.In the future,the development directions of navigation warfare will focus on three aspects:enhancing satellite capabilities,tackling core technical challenges,and building a multi-dimensional system.
文摘In this work,the generation of high signal-to-noise ratio(SNR)single-frequency microwave signal without noise sidebands is demonstrated based on the interaction of integrated all-fiber lasers.The microwave signals are generated by the interference between a narrow linewidth Brillouin pump light from a single-frequency laser and the Stokes light generated by it.Firstly,the linewidths of the Stokes lights are compressed to~43 Hz based on the stimulated Brillouin scattering(SBS)effect,which ensures that the frequency noise is as low as possible.And then,the relative intensity noise(RIN)of the first order Stokes light is reduced by 21 dB/Hz based on the noise dynamics principle in cascaded SBS effect.By simultaneously reducing the frequency noise and the intensity noise of the coherent signals,the noise sidebands of microwave signals are completely suppressed.As result,the SNR of the microwave signal is improved from 48 dB to 84 dB at the first-order Brillouin frequency shift of 9.415 GHz.Meanwhile,a microwave signal with a SNR of 70 dB is generated at the second-order Brillouin frequency shift of 18.827 GHz.This kind of microwave signals with narrow linewidth and high SNR can provide higher detection resolution and higher transmission efficiency for applications on radar,satellite communication and so on.
基金supported by the National Key Research and Development Program of China(2022YFB3504501)the National Natural Science Foundation of China(52274355)。
文摘This paper focuses on the preparation of rare earth oxide products from rare earth chloride solutions during the rare earth extraction and separation processes,as well as the recycling of magnesium chloride solutions.It proposes the idea of introducing spray pyrolysis technology into the rare earth extraction and separation processes.This paper briefly describes the development history of chloride spray pyrolysis technology,focusing on the research status and application progress of rare earth chloride solution and magnesium chloride solution spray pyrolysis technology,as well as spray pyrolysis equipment.The paper also analyzes the challenges and technical intricacies associated with applying spray pyrolysis technology to chloride solutions in the rare earth extraction and separation processes.Additionally,it explores future trends and proposes strategies to facilitate the full recycling of acids and bases,streamline the process flow,and enhance the prospects for green and low-carbon rare earth metallurgy.
文摘This article aims to provide a comprehensive analysis of the role and development prospects of direct satellite-to-phone technology in the global communication landscape.It explores the importance,current development status,key technical challenges,future directions,and countermeasures of this technology from multiple dimensions.The article explains the significance and necessity of direct satellite-to-phone technology in the global communication field,discusses its development background and importance as one of the key technologies in the 6G era,and outlines the research objectives,methodology,and structure of the paper.Additionally,the article reviews and analyzes the development history of direct satellite-to-phone technology on a global scale,discusses the key technical points in achieving this technology,and predicts its potential role and development direction in future communication systems from the perspective of 6G network architecture.It also explores new application scenarios and service models that may emerge from technological advancements,as well as their impact on future communication networks.The development history of direct satellite-to-phone technology and its role in current and future communication networks are emphasized,highlighting its value in promoting global communication infrastructure construction.The article also proposes improvement suggestions for existing issues and points out future research directions.
文摘This paper focuses on the key issues of tool wear condition monitoring in the field of machining,and deeply discusses the application of digital twin technology in this aspect.This paper expounds the principle and architecture of digital twin technology,analyzes its specific methods in tool wear data acquisition,modeling,simulation,and real-time monitoring,and shows the significant advantages of this technology in improving the accuracy of tool wear monitoring and realizing predictive maintenance.At the same time,the challenges faced by digital twin technology in tool wear condition monitoring are discussed,and the corresponding development direction is put forward,aiming to provide theoretical reference and practical guidance for optimizing tool management by digital twin technology in the machining industry.
文摘This paper focuses on the application of artificial intelligence(AI)technology in the reform of college English teaching.By analyzing the current situation of college English teaching and the advantages of AI technology,it explores how AI technology can be applied in different aspects of college English teaching,such as teaching content delivery,language practice,and assessment.It also discusses the challenges and opportunities brought by AI technology in the teaching reform process and proposes corresponding construction strategies to promote the deep integration of AI technology and college English teaching,aiming to improve the quality and efficiency of college English teaching and develop students’comprehensive English application ability.
基金AI-Empowered Practical Course Teaching Project of Zhuhai College of Science and Technology(Project No.:SYSG2025025)。
文摘With the continuous development of science and technology,we have already entered the digital age.While big data,artificial intelligence,and digital twin technology provide convenience for various fields of people’s lives,they also bring new opportunities for the innovation and development of competitive cheerleading.Especially for the training of aerial techniques in competitive cheerleading,which has high requirements for accuracy,coordination,and safety,the traditional training model has problems such as empiricism and insufficient risk prediction,which directly affect the quality of training.This article discusses the application value and application countermeasures of digital twin technology in the aerial techniques of competitive cheerleading,hoping to provide some reference for relevant personnel.
基金financial support from SATREPS project(vote number:R.J130000.7801.4L977)KPM-UTM Grant(vote number:R.J130000.7301.4L997).
文摘The treatment of POME related contamination is complicated due to its high organic contents and complex composition.Membrane technology is a prominent method for removing POME contaminants on account of its efficiency in removing suspended particles,organic substances,and contaminants from wastewater,leading to the production of high-quality treated effluent.It is crucial to achieve efficient POME treatment with minimum fouling through membrane advancement to ensure the sustainability for large-scale applications.This article comprehensively analyses the latest advancements in membrane technology for the treatment of POME.A wide range of membrane types including forward osmosis,microfiltration,ultrafiltration,nanofiltration,reverse osmosis,membrane bioreactor,photocatalytic membrane reactor,and their combinations is discussed in terms of the innovative design,treatment efficiencies and antifouling properties.The strategies for antifouling membranes such as self-healing and self-cleaning membranes are discussed.In addition to discussing the obstacles that impede the broad implementation of novel membrane tech nologies in POME treatment,the article concludes by delineating potential avenues for future research and policy considerations.The understanding and insights are expected to enhance the application ofmembrane-basedmethods in order to treat POME more efficiently;this will be instrumental in the reduction of environmental pollution.
