The capital of Georgia</span><span style="font-family:Verdana;">—Tbilisi has a very convenient location and is a node of the transit corridor. Along with natural-geological conditions, its compl...The capital of Georgia</span><span style="font-family:Verdana;">—Tbilisi has a very convenient location and is a node of the transit corridor. Along with natural-geological conditions, its complexity is due to the rapid demographic growth of the city in a highly “sensitive” area of the geological environment and the pressure of high engineering and agricultural activities. In Tbilisi</span></span><span style="font-family:Verdana;">,</span><span style="font-family:Verdana;"> it is observed almost all type</span><span style="font-family:Verdana;">s</span><span style="font-family:""><span style="font-family:Verdana;"> of geological hazards, including landslide-gravitational, suffosion, debris/mudflows, river </span><span style="font-family:Verdana;">bank erosion and inundation </span></span><span style="font-family:Verdana;">were </span><span style="font-family:Verdana;">caused by groundwater. These hazard</span><span style="font-family:Verdana;">s</span><span style="font-family:Verdana;"> cause</span><span style="font-family:""><span style="font-family:Verdana;"> high damages to the residential houses and other infrastructure facilities. Most importantly and most tragically is that these kind of negative geological events are often accompanied by human casualties. The study discusses the geological processes developed in March 2021 in the corridor of the Vashlij</span><span style="font-family:Verdana;">vari-Lisi road (Machavariani Street). The information obtained from the study,</span><span style="font-family:Verdana;"> reflects the triggering factors of the geological hazards, also damages caused by them, and provides recommendations for short-term and long-term protective measures that should ensure the sustainable operation of the road and other infrastructure facilities.展开更多
During 13-14 June 2015 heavy rainfall in the Riv. Vere basin area and its tributaries caused a drastic increase in the water level and triggered/activated large-scale landslide and debrisflow events. This put the Tskn...During 13-14 June 2015 heavy rainfall in the Riv. Vere basin area and its tributaries caused a drastic increase in the water level and triggered/activated large-scale landslide and debrisflow events. This put the Tskneti-Samadlo and Tsnketi-Akhal- daba motorways out of order. Residential buildings and miscellaneous infrastructural facilities, buildings and structures and Tbilisi Zoo located at the low elevations in the Riv. Vere Gorge were significantly damaged or/and totally destroyed. 23 persons died during the disaster. This study presents the results on an analysis of the landslides/ debrisflows in the riv. Vere catchment and discusses main triggering factors of natural disaster, statistics for the prior period, and geodynamic situation of Akhaldaba “big” landslide developed at the Tskneti-Samadlo road section. It is given recommendations for future activities to reduce landslide/debrisflow hazard in this catchment.展开更多
Abstract: The main purpose of the research was to study a role and place of managers in maintaining staff policy at pharmaceutical companies. It was interesting to see how Georgian pharmaceutical companies are gettin...Abstract: The main purpose of the research was to study a role and place of managers in maintaining staff policy at pharmaceutical companies. It was interesting to see how Georgian pharmaceutical companies are getting new employees at work, what is the priority of the new recruits? What methods are used for selection and recruitment? There were made inquiries by the way of filling applications, which (the applications) were given to the managers ofAversi, PSP, GPC, Pharmadepot and Pharmaceutical House. 50 managers were interviewed totally. It was established that pharmaceutical company management appoints people on the position of pharmacist-managers mainly on the basis of contract (90%). At present, the pharmacist education does not comply with the competence, so 55% of interviewed managers are bachelors, 45% are masters. In order to increase the management's qualifications, pharmaceutical companies are conducting seminars (50%), trainings (30%), and testing (20%). Staff administration in the pharmacies is mainly carried out by the company administration (75%), rarely by managers (25%), but very often the administration takes into consideration the manager's opinion; employees are accepted by testing-interview (70%) or CV (30%). Professional career and experience of the newly employed staff are not highly important (50/50), and the company prefers to educate and share practice to the personnel itself. It is possible to conclude that today the pharmacist-managers of the pharmacies are working in accordance with the contractual fights and obligations signed with the employers and pharmaceutical activities regulated under non-governmental institutes. As a result, it is important to be included special features of pharmaceutical management and the recommendations offered by the World Health Organization and the International Pharmaceutical Federation in the articles of regulatory laws.展开更多
Background:After the outbreak of COVID-19 in Georgia,the number of patients visiting pharmacies has increased.It became relevant to research the importance of Pharmaceutical Care inprevention of COVID-19.The aim of th...Background:After the outbreak of COVID-19 in Georgia,the number of patients visiting pharmacies has increased.It became relevant to research the importance of Pharmaceutical Care inprevention of COVID-19.The aim of the study was to understand the attitudes of patients and physicians regarding the involvement of pharmacists in prevention of COVID-19,after the spring and autumn waves of pandemic;also,what role can pharmacists take in the future and whether they can transfer Good Pharmaceutical Practice(GPP)to Georgia.Study also tried to capture overall attitudes towards involving pharmacists in healthcare projects such as population rapid testing and vaccinations.Methods:522 patients,1289 pharmacists,and 200 physicians were surveyed regarding their attitudes toward pharmaceutical care during COVID-19 pandemic.Results:The study found that 82.2%of surveyed patients who visited pharmacy during pandemic bought medication and COVID-19 preventive items(face mask,disinfectants,etc.).Out of the surveyed participants,66.9%of patients and 77.1%of pharmacists believe that recommendations given by pharmacists play an important role in the prevention of COVID-19.Study also revealed that 76.6%of pharmacists and 79.3%of patients agree with the statement,the pharmacist should be able to decide whether to choose over-the-counter medications for a patient or refer the patient to a physician.91.8%of patients and 78.3%of pharmacists believe that during a pandemic pharmacist should provide patients who visit pharmacies with complaints of flu,cold,and fever with Pharmaceutical Care;which is agreed by 41.7%of physicians.63.1%of patients,52%of pharmacists,and 45%of physicians have a positive attitude towards administering rapid testing of COVID-19 by pharmacists.The desire for pharmacists to be involved in vaccination was expressed most in patients(43.6%),followed by pharmacists(38.7%),and physicians(36.7%).Conclusions:The study showed similar attitudes of patients and pharmacists-Pharmaceutical Care plays an important role in pandemic prevention.The attitude of patients and pharmacists is positive regarding administering Pharmaceutical Care for patients who come in pharmacies with symptoms of flu and cold.Physicians had more cautious attitude towards the issue,indicating that they may see risks of spreading the virus and aggravating patients’conditions.Most patients who participated in the study believe that pharmacists should be involved in pandemic prevention activities-COVID-19 tests and vaccinations.It is recommended that Georgian healthcare system develops projects that support collaboration of medical professionals and bring us closer to Good Pharmacy Practice(GPP).Training of pharmacists along with physicians in scope of pandemic prevention projects should be planned.展开更多
The integration of machine learning(ML)into geohazard assessment has successfully instigated a paradigm shift,leading to the production of models that possess a level of predictive accuracy previously considered unatt...The integration of machine learning(ML)into geohazard assessment has successfully instigated a paradigm shift,leading to the production of models that possess a level of predictive accuracy previously considered unattainable.However,the black-box nature of these systems presents a significant barrier,hindering their operational adoption,regulatory approval,and full scientific validation.This paper provides a systematic review and synthesis of the emerging field of explainable artificial intelligence(XAI)as applied to geohazard science(GeoXAI),a domain that aims to resolve the long-standing trade-off between model performance and interpretability.A rigorous synthesis of 87 foundational studies is used to map the intellectual and methodological contours of this rapidly expanding field.The analysis reveals that current research efforts are concentrated predominantly on landslide and flood assessment.Methodologically,tree-based ensembles and deep learning models dominate the literature,with SHapley Additive exPlanations(SHAP)frequently adopted as the principal post-hoc explanation technique.More importantly,the review further documents how the role of XAI has shifted:rather than being used solely as a tool for interpreting models after training,it is increasingly integrated into the modeling cycle itself.Recent applications include its use in feature selection,adaptive sampling strategies,and model evaluation.The evidence also shows that GeoXAI extends beyond producing feature rankings.It reveals nonlinear thresholds and interaction effects that generate deeper mechanistic insights into hazard processes and mechanisms.Nevertheless,several key challenges remain unresolved within the field.These persistent issues are especially pronounced when considering the crucial necessity for interpretation stability,the demanding scholarly task of reliably distinguishing correlation from causation,and the development of appropriate methods for the treatment of complex spatio-temporal dynamics.展开更多
Liver regeneration(LR)following partial hepatectomy(PH)is a unique and complex physiological response that restores hepatic mass and function through tightly orchestrated cellular and molecular events.Traditionally vi...Liver regeneration(LR)following partial hepatectomy(PH)is a unique and complex physiological response that restores hepatic mass and function through tightly orchestrated cellular and molecular events.Traditionally viewed as a proliferation-driven process,LR is now understood to involve both hepatocyte hyperplasia and hypertrophy,triggered primarily by hemodynamic alterations such as increased portal pressure and shear stress.These promote LR through endothelial–hepatocyte communication via activation of Piezo1-a mechanosensitive ion channel highly expressed in vascular endothelial cells.This channel is considered one of the potential upstream activators of molecular cascades including the interleukin(IL)-6/signal transducer and activator of transcription 3,tumour necrosis factor-alpha/nuclear factor-kappa B,Wnt/β-catenin,Hippo/YAP,transforming growth factor-beta,and Notch pathways,which contribute variably to the proliferation,differentiation,or suppression of hepatic cells.Novel insights into the IL-22 and IL-33 signaling axes,bile acid and glutamine metabolism,and the role of intestinal microbiota are also presented as promising emerging targets.This review synthesizes current insights into the interplay between mechanical cues,key signaling pathways,and metabolic reprogramming that govern early regenerative responses.We explore the mechanisms dictating the balance between hyperplasia and hypertrophy,noting that hypertrophy predominates after minor resections,while proliferation is dominant in larger resections.Polyploidization emerges as a significant adaptive mechanism,contributing to hepatocyte survival and tissue remodeling.The importance of ductular reactions,microvascular adjustments,and extracellular matrix dynamics in lobular architecture remodeling is also highlighted.The study explores the occurrence of ductular reactions in both minor and major resections,particularly within the granulation tissue near dissection areas.The paper also examines structural remodeling in regenerated liver tissue,demonstrating ongoing transformations in hepatocyte morphology and sinusoidal architecture even months after PH,and emphasizing that the termination of liver mass regrowth does not equate to the cessation of LR.展开更多
Bruxism, characterized by involuntary clenching or grinding of teeth, affects approximately 10% - 20% of adults globally and has significant implications for dental and systemic health. Emerging AI-driven diagnostic t...Bruxism, characterized by involuntary clenching or grinding of teeth, affects approximately 10% - 20% of adults globally and has significant implications for dental and systemic health. Emerging AI-driven diagnostic tools have demonstrated a 25% improvement in identifying nocturnal bruxism compared to conventional methods. This study explores the etiology, pathogenesis, and treatment modalities of bruxism, integrating cutting-edge advancements like neuromodulation and personalized medicine. Furthermore, socioeconomic factors and access disparities are analyzed to propose comprehensive strategies for improving patient outcomes. Current management strategies include behavioral therapies, orthodontic appliances, pharmacological interventions, physical therapy, and, in severe cases, surgical options. Emerging technologies, such as artificial intelligence, personalized medicine, and neuromodulation, are highlighted as promising advancements in bruxism diagnosis and treatment. Additionally, the study underscores the socioeconomic and ethical dimensions of bruxism care, advocating for interdisciplinary collaboration, patient education, and equitable access to innovative treatments. This research aims to contribute to improved understanding and management of bruxism, enhancing patient outcomes and quality of life.展开更多
BACKGROUND Living donor liver transplantation(LDLT)is a crucial alternative to deceased donor transplantation,especially in regions with limited access to cadaveric organs.Right lobe graft implantation into the inferi...BACKGROUND Living donor liver transplantation(LDLT)is a crucial alternative to deceased donor transplantation,especially in regions with limited access to cadaveric organs.Right lobe graft implantation into the inferior vena cava(IVC)requires advanced surgical techniques to optimize outcomes and reduce complications.AIM To compare two venous anastomosis techniques—direct polytetrafluoroethylene(PTFE)grafting of V5-V8 veins to the IVC vs triangulation to the right hepatic vein(RHV)—in terms of graft viability and postoperative outcomes.METHODS A retrospective analysis was conducted on 96 patients who underwent LDLT with right lobe grafts between 2014 and 2023.Patients were divided into three groups:(1)No venous outflow reconstruction;(2)PTFE graft direct anastomosis to the IVC;and(3)PTFE graft anastomosis using triangulation to the RHV.Perioperative and postoperative outcomes,including bile duct complications,alanine aminotransferase/aspartate aminotransferase levels,and graft perfusion,were compared across groups.RESULTS Group 3(triangulation to RHV)showed significantly improved venous outflow,fewer complications,and faster normalization of liver function tests.Bile duct complications were highest in group 1(12.8%)and lowest in group 3(7%).Doppler ultrasonography revealed better graft perfusion in group 3 compared to groups 1 and 2.CONCLUSION Triangulation to the RHV improves graft viability,reduces biliary complications,and enhances early postoperative outcomes compared to direct PTFE grafting to the IVC.展开更多
BACKGROUND Obese patients(body mass index≥30 kg/m^(2))undergoing isolated aortic valve replacement(AVR)face increased surgical risks due to comorbidities.Partial upper sternotomy(PUS),a minimally invasive approach,ma...BACKGROUND Obese patients(body mass index≥30 kg/m^(2))undergoing isolated aortic valve replacement(AVR)face increased surgical risks due to comorbidities.Partial upper sternotomy(PUS),a minimally invasive approach,may reduce complications compared to full median sternotomy(FMS).We hypothesize that PUS improves outcomes over FMS in obese patients undergoing AVR.AIM To compare the efficacy and safety of PUS vs FMS in obese patients undergoing isolated AVR.METHODS This systematic review and meta-analysis followed PRISMA guidelines,searching PubMed,EMBASE,and Cochrane databases for observational studies comparing PUS vs FMS in obese patients undergoing AVR.Outcomes were analyzed using odds ratios(OR),mean differences(MD),95%confidence intervals(CI),I^(2)statistic,and Newcastle-Ottawa Scale was used for quality assessment.RESULTS Four observational studies involving 677 patients were analyzed.PUS reduced intensive care unit stay(MD-2.67 days,95%CI:-4.43 to-0.90,P=0.003,I^(2)=78%)but increased cardiopulmonary bypass time(MD 5.62 minutes,95%CI:-0.36 to 11.59,I^(2)=55%).No differences were observed in renal failure(OR 1.13,95%CI:0.63-2.94,I^(2)=0%),atrial fibrillation(OR 0.81,95%CI:0.43-1.54,I^(2)=30%),reexploration(OR 1.09,95%CI:0.48-2.47,I^(2)=0%),postoperative bleeding(OR 1.48,95%CI:0.53-4.15,I^(2)=60%),wound infection(OR 1.23,95%CI:0.70-2.14,I^(2)=0%),hospital stay(MD 0.51 days,95%CI:-4.13 to 5.15,I^(2)=90%),or cross-clamp time(MD 4.03 minutes,95%CI:-0.75 to 8.80,I^(2)=50%).CONCLUSION PUS is safe and effective for obese patients undergoing AVR,reducing intensive care unit stay and enhancing recovery,provided surgical expertise is available.展开更多
The undercurrent research survey explores the roles of nonlocality and strain gradient size dependencies in nonlinear asymmetric buckling of shallow nanoscale arches having dissimilar end conditions through a numerica...The undercurrent research survey explores the roles of nonlocality and strain gradient size dependencies in nonlinear asymmetric buckling of shallow nanoscale arches having dissimilar end conditions through a numerical analysis.The arches,made from a functionally graded graphene nanofiller reinforced composite(FG-GNRC),are subjected to discretional radial concentrated loads along with converting of temperature.To account for the size dependencies,the exploration is carried out stemming from the nonlocal strain gradient theory(NSGT)in the sense of a quasi-2D parabolic shear flexible concept of curved beam.The material properties of the contemplated FG-GNRC sandwich are determined using the modified Halpin-Tsai micromechanics model.Subsequently,an extended isogeometric analysis(XIGA)is manipulated comprising insertion plus multiplication of knots to achieve the demanded lower continuity allocated to the integration between flexural and tangential reflexes.It is perceived that the both softening and stiffening concomitants assigned to the salient concentrated radial loads obtained by the developed NSGT-based XIGA diminish from the first upper limit to the second one,and then likewise from the first lower limit to the second one.Although,by becoming the upsurge in temperature higher,these softening and stiffening concomitants get more remarkable.展开更多
We review recent experimental and theoretical results for the electromagnetic form factors of hyperons(Y)in the timelike region,accessible in the reactions e^(+)e^(-)→YY.Specifically,we focus on the final statesΛΛ...We review recent experimental and theoretical results for the electromagnetic form factors of hyperons(Y)in the timelike region,accessible in the reactions e^(+)e^(-)→YY.Specifically,we focus on the final statesΛΛ,ΛΣ^(0)/Λ,Σ^(0)Λ,■■,andΩΩ.TheΛ_(c)Λ_(c)system is also discussed.展开更多
Objective:To assess the level of nursing students’knowledge about delirium and its associated risk factors.Delirium is a clinical syndrome characterized by alterations in cognition and psychomotor activity.Since deli...Objective:To assess the level of nursing students’knowledge about delirium and its associated risk factors.Delirium is a clinical syndrome characterized by alterations in cognition and psychomotor activity.Since delirium is common among geriatric patients,adequate preparedness of nursing students to assess and manage delirious geriatric patients is necessary to improve potential nurses’quality of care and communication with this group.Limited research work was conducted to address nursing students’knowledge about delirium.Methods:This cross-sectional descriptive study was conducted from October 2022 to February 2023.A convenience sampling was used,and 319 valid questionnaires were obtained from nursing students from six Jordanian governmental and private universities,who were at least in their third academic year.An adopted delirium knowledge scale was used to collect data.Descriptive statistics and an independent t-test were used for data analysis.Results:The mean for general knowledge about delirium was 57.5%.The mean for knowledge of delirium risk factors was 61.8%.Nursing students in their fourth academic year scored significantly higher on both general knowledge and risk knowledge scales than students in the third academic year.Conclusions:Nursing students’knowledge regarding delirium and its risk factors was low.Educational efforts should be maximized for incorporating and addressing the topic of delirium in the undergraduate nursing curriculum.Implications of this study include revising nursing curricula to ensure that students receive enough education on delirium,including its detection,diagnosis,and management.The implications also include giving nursing students the chance to gain experience in caring for delirious patients and providing them with the tools and resources they need to assess and manage delirium.展开更多
Accurate daily suspended sediment load(SSL)prediction is essential for sustainable water resource management,sediment control,and environmental planning.However,SSL prediction is highly complex due to its nonlinear an...Accurate daily suspended sediment load(SSL)prediction is essential for sustainable water resource management,sediment control,and environmental planning.However,SSL prediction is highly complex due to its nonlinear and dynamic nature,making traditional empirical models inadequate.This study proposes a novel hybrid approach,integrating the Adaptive Neuro-Fuzzy Inference System(ANFIS)with the Gradient-Based Optimizer(GBO),to enhance SSL forecasting accuracy.The research compares the performance of ANFIS-GBO with three alternative models:standard ANFIS,ANFIS with Particle Swarm Optimization(ANFIS-PSO),and ANFIS with Grey Wolf Optimization(ANFIS-GWO).Historical SSL and streamflow data from the Bailong River Basin,China,are used to train and validate the models.The input selection process is optimized using the Multivariate Adaptive Regression Splines(MARS)method.Model performance is evaluated using statistical metrics such as Root Mean Square Error(RMSE),Mean Absolute Error(MAE),Mean Absolute Percentage Error(MAPE),Nash Sutcliffe Efficiency(NSE),and Determination Coefficient(R^(2)).Additionally,visual assessments,including scatter plots,Taylor diagrams,and violin plots,provide further insights into model reliability.The results indicate that including historical SSL data improves predictive accuracy,with ANFIS-GBO outperforming the other models.ANFIS-GBO achieves the lowest RMSE and MAE and the highest NSE and R^(2),demonstrating its superior learning ability and adaptability.The findings highlight the effectiveness of nature-inspired optimization algorithms in enhancing sediment load forecasting and contribute to the advancement of AI-based hydrological modeling.Future research should explore the integration of additional environmental and climatic variables to enhance predictive capabilities further.展开更多
Water quality is always one of the most important factors in human health. Artificial intelligence models are respected methods for modeling water quality. The evolutionary algorithm (EA) is a new technique for improv...Water quality is always one of the most important factors in human health. Artificial intelligence models are respected methods for modeling water quality. The evolutionary algorithm (EA) is a new technique for improving the performance of artificial intelligence models such as the adaptive neuro fuzzy inference system (ANFIS) and artificial neural networks (ANN). Attempts have been made to make the models more suitable and accurate with the replacement of other training methods that do not suffer from some shortcomings, including a tendency to being trapped in local optima or voluminous computations. This study investigated the applicability of ANFIS with particle swarm optimization (PSO) and ant colony optimization for continuous domains (ACOR) in estimating water quality parameters at three stations along the Zayandehrood River, in Iran. The ANFIS-PSO and ANFIS-ACOR methods were also compared with the classic ANFIS method, which uses least squares and gradient descent as training algorithms. The estimated water quality parameters in this study were electrical conductivity (EC), total dissolved solids (TDS), the sodium adsorption ratio (SAR), carbonate hardness (CH), and total hardness (TH). Correlation analysis was performed using SPSS software to determine the optimal inputs to the models. The analysis showed that ANFIS-PSO was the better model compared with ANFIS-ACOR. It is noteworthy that EA models can improve ANFIS' performance at all three stations for different water quality parameters.展开更多
The article considers the variability of Nenskra and Nakra River basins glaciers’ parameters in the years of 1911-2014. Nenskra and Nakra River basins are located on the southern slope of the Great Caucasus, between ...The article considers the variability of Nenskra and Nakra River basins glaciers’ parameters in the years of 1911-2014. Nenskra and Nakra River basins are located on the southern slope of the Great Caucasus, between the Kharikhra, Shdavleri and Tsalgmili ranges, in Georgia, in particular in the Enguri River basin. In our research we used the catalogue of the glaciers of Georgia compiled by K. Podozerskiy in 1911. We also used the military topographic maps with the scale of 1:25,000 and 1:50,000 drawn up in 1960 (in former Soviet Union), where there are the glaciers mapped in detail and the ends of their ice tongues on the southern slope of Great Caucasus of those times. We also used the remote sensing method, which is the best modern way for the study of the dynamics of glaciers and this method is remarkable by a quick obtaining of results. The spectral images of the Landsat L8 OLI/TIRS (Operational Land Imager and Thermal Infrared Sensor) (USGS) received from the “Landsat” artificial satellite are the necessary materials for our study. We also used the field survey materials of 2014 (GPS data). The latest statistical information is also given about the glaciers located in the individual river basins;their morphological types, exposition and the dynamics are considered according to the individual years.展开更多
The rapid propagation of multidrug resistant bacterial strains is leading to renewed interest in bacteriophage therapy.With challenges in the treatment of bacterial infections,it is essential for people worldwide to u...The rapid propagation of multidrug resistant bacterial strains is leading to renewed interest in bacteriophage therapy.With challenges in the treatment of bacterial infections,it is essential for people worldwide to understand how alternative approaches,such as bacteriophages,could be used to combat antibiotic resistant bacteria.The Eliava Institute展开更多
Phanerozoic geodynamic development of the Tethys ocean revealed at Eurasian active margin is manifested in pre-and post-collision stages.The Phanerozoic crust was already divided into sialic and basaltic crusts and ri...Phanerozoic geodynamic development of the Tethys ocean revealed at Eurasian active margin is manifested in pre-and post-collision stages.The Phanerozoic crust was already divided into sialic and basaltic crusts and rigid upper mantle.The precious and nonferrous metals were redistributed between them.In the sialic crust,precious metals are concentrated: Au,Ag and Pb,in basaltic crust—zinc,the copper mainly rests in the mantle.Phanerozoic plate-tectonics was manifested in the following settings: island arc,inter/backarc and oceanic.Island arc setting correlates with steady-state subduction and controlled by calc-alkaline volcanism.At this stage,the sialic,basaltic crust and mantle material participate in volcanism,whereas the subducted slab plunged in mantle,the metallogenic indicators are Au,Pb,Zn and Cu.The stage of inter/backarc is related to steepening of subducting slab,because mantle diapir incursion provokes the rifting.At the initial stage and at stage of slackening rifting,when the sialic crust is not yet spread out from zone of volcanic activity,mineralization was represented by subalkaline trachydacites,shoshonite and alkali basaltic volcanism(volcanological indicators)and Au and Pb are participated with Zn and Cu in mineralization.The strengthening of steepening with mantle diapir incursion on higher level rifting spread out the sialic crust,volcanism on this stage is tholeiitic and mineralization is represented by zinc-copper-pyrite VMS(Volcanogenic Massive Sulphide)ores.The minor ocean setting is controlled by the most intensive spreading provoked by incursion mantle diapir at highest level,and spread out the basaltic crust as well,and volcanism belongs to ophiolites with dunite-peridotite magmatic activity.The mineralization was represented by copper-pyrite ores and single metallogenic indicator is the copper.The convergence of Eurasian and Afro-Arabian continents and closing of Tethys Ocean resulted in transferring the pre-collision stage in post-collision,characterized by trace elements Sb,W,Mo,Hg,as geochemical and metallogenic indicator of the postcollision setting.展开更多
The given article presents an analytical model developed for a multichannel technical queuing system with time redundancy for operability management, subsystems of reliable periodical control of sudden and gradual fai...The given article presents an analytical model developed for a multichannel technical queuing system with time redundancy for operability management, subsystems of reliable periodical control of sudden and gradual failure detection and a subsystem for system recovery after failure. It is assumed in the model that the failures are governed by the Poisson probability distribution law and the times of reliable control and system recovery after failures are governed by an arbitrary law of probability distribution, in the general case depending on the number of servicers. The paper defines probabilities of accomplishment of certain task volumes by the system within a priori defined time intervals, taking into consideration its reliability characteristics.展开更多
The main aim of this article is to prove that the maximal operator σ^k* of the Marcinkiewicz-Fejer means of the two-dimensional Fourier series with respect to Walsh- Kaczmarz system is bounded from the Hardy space H...The main aim of this article is to prove that the maximal operator σ^k* of the Marcinkiewicz-Fejer means of the two-dimensional Fourier series with respect to Walsh- Kaczmarz system is bounded from the Hardy space H2/3 to the space weak-L2/3.展开更多
文摘The capital of Georgia</span><span style="font-family:Verdana;">—Tbilisi has a very convenient location and is a node of the transit corridor. Along with natural-geological conditions, its complexity is due to the rapid demographic growth of the city in a highly “sensitive” area of the geological environment and the pressure of high engineering and agricultural activities. In Tbilisi</span></span><span style="font-family:Verdana;">,</span><span style="font-family:Verdana;"> it is observed almost all type</span><span style="font-family:Verdana;">s</span><span style="font-family:""><span style="font-family:Verdana;"> of geological hazards, including landslide-gravitational, suffosion, debris/mudflows, river </span><span style="font-family:Verdana;">bank erosion and inundation </span></span><span style="font-family:Verdana;">were </span><span style="font-family:Verdana;">caused by groundwater. These hazard</span><span style="font-family:Verdana;">s</span><span style="font-family:Verdana;"> cause</span><span style="font-family:""><span style="font-family:Verdana;"> high damages to the residential houses and other infrastructure facilities. Most importantly and most tragically is that these kind of negative geological events are often accompanied by human casualties. The study discusses the geological processes developed in March 2021 in the corridor of the Vashlij</span><span style="font-family:Verdana;">vari-Lisi road (Machavariani Street). The information obtained from the study,</span><span style="font-family:Verdana;"> reflects the triggering factors of the geological hazards, also damages caused by them, and provides recommendations for short-term and long-term protective measures that should ensure the sustainable operation of the road and other infrastructure facilities.
文摘During 13-14 June 2015 heavy rainfall in the Riv. Vere basin area and its tributaries caused a drastic increase in the water level and triggered/activated large-scale landslide and debrisflow events. This put the Tskneti-Samadlo and Tsnketi-Akhal- daba motorways out of order. Residential buildings and miscellaneous infrastructural facilities, buildings and structures and Tbilisi Zoo located at the low elevations in the Riv. Vere Gorge were significantly damaged or/and totally destroyed. 23 persons died during the disaster. This study presents the results on an analysis of the landslides/ debrisflows in the riv. Vere catchment and discusses main triggering factors of natural disaster, statistics for the prior period, and geodynamic situation of Akhaldaba “big” landslide developed at the Tskneti-Samadlo road section. It is given recommendations for future activities to reduce landslide/debrisflow hazard in this catchment.
文摘Abstract: The main purpose of the research was to study a role and place of managers in maintaining staff policy at pharmaceutical companies. It was interesting to see how Georgian pharmaceutical companies are getting new employees at work, what is the priority of the new recruits? What methods are used for selection and recruitment? There were made inquiries by the way of filling applications, which (the applications) were given to the managers ofAversi, PSP, GPC, Pharmadepot and Pharmaceutical House. 50 managers were interviewed totally. It was established that pharmaceutical company management appoints people on the position of pharmacist-managers mainly on the basis of contract (90%). At present, the pharmacist education does not comply with the competence, so 55% of interviewed managers are bachelors, 45% are masters. In order to increase the management's qualifications, pharmaceutical companies are conducting seminars (50%), trainings (30%), and testing (20%). Staff administration in the pharmacies is mainly carried out by the company administration (75%), rarely by managers (25%), but very often the administration takes into consideration the manager's opinion; employees are accepted by testing-interview (70%) or CV (30%). Professional career and experience of the newly employed staff are not highly important (50/50), and the company prefers to educate and share practice to the personnel itself. It is possible to conclude that today the pharmacist-managers of the pharmacies are working in accordance with the contractual fights and obligations signed with the employers and pharmaceutical activities regulated under non-governmental institutes. As a result, it is important to be included special features of pharmaceutical management and the recommendations offered by the World Health Organization and the International Pharmaceutical Federation in the articles of regulatory laws.
文摘Background:After the outbreak of COVID-19 in Georgia,the number of patients visiting pharmacies has increased.It became relevant to research the importance of Pharmaceutical Care inprevention of COVID-19.The aim of the study was to understand the attitudes of patients and physicians regarding the involvement of pharmacists in prevention of COVID-19,after the spring and autumn waves of pandemic;also,what role can pharmacists take in the future and whether they can transfer Good Pharmaceutical Practice(GPP)to Georgia.Study also tried to capture overall attitudes towards involving pharmacists in healthcare projects such as population rapid testing and vaccinations.Methods:522 patients,1289 pharmacists,and 200 physicians were surveyed regarding their attitudes toward pharmaceutical care during COVID-19 pandemic.Results:The study found that 82.2%of surveyed patients who visited pharmacy during pandemic bought medication and COVID-19 preventive items(face mask,disinfectants,etc.).Out of the surveyed participants,66.9%of patients and 77.1%of pharmacists believe that recommendations given by pharmacists play an important role in the prevention of COVID-19.Study also revealed that 76.6%of pharmacists and 79.3%of patients agree with the statement,the pharmacist should be able to decide whether to choose over-the-counter medications for a patient or refer the patient to a physician.91.8%of patients and 78.3%of pharmacists believe that during a pandemic pharmacist should provide patients who visit pharmacies with complaints of flu,cold,and fever with Pharmaceutical Care;which is agreed by 41.7%of physicians.63.1%of patients,52%of pharmacists,and 45%of physicians have a positive attitude towards administering rapid testing of COVID-19 by pharmacists.The desire for pharmacists to be involved in vaccination was expressed most in patients(43.6%),followed by pharmacists(38.7%),and physicians(36.7%).Conclusions:The study showed similar attitudes of patients and pharmacists-Pharmaceutical Care plays an important role in pandemic prevention.The attitude of patients and pharmacists is positive regarding administering Pharmaceutical Care for patients who come in pharmacies with symptoms of flu and cold.Physicians had more cautious attitude towards the issue,indicating that they may see risks of spreading the virus and aggravating patients’conditions.Most patients who participated in the study believe that pharmacists should be involved in pandemic prevention activities-COVID-19 tests and vaccinations.It is recommended that Georgian healthcare system develops projects that support collaboration of medical professionals and bring us closer to Good Pharmacy Practice(GPP).Training of pharmacists along with physicians in scope of pandemic prevention projects should be planned.
文摘The integration of machine learning(ML)into geohazard assessment has successfully instigated a paradigm shift,leading to the production of models that possess a level of predictive accuracy previously considered unattainable.However,the black-box nature of these systems presents a significant barrier,hindering their operational adoption,regulatory approval,and full scientific validation.This paper provides a systematic review and synthesis of the emerging field of explainable artificial intelligence(XAI)as applied to geohazard science(GeoXAI),a domain that aims to resolve the long-standing trade-off between model performance and interpretability.A rigorous synthesis of 87 foundational studies is used to map the intellectual and methodological contours of this rapidly expanding field.The analysis reveals that current research efforts are concentrated predominantly on landslide and flood assessment.Methodologically,tree-based ensembles and deep learning models dominate the literature,with SHapley Additive exPlanations(SHAP)frequently adopted as the principal post-hoc explanation technique.More importantly,the review further documents how the role of XAI has shifted:rather than being used solely as a tool for interpreting models after training,it is increasingly integrated into the modeling cycle itself.Recent applications include its use in feature selection,adaptive sampling strategies,and model evaluation.The evidence also shows that GeoXAI extends beyond producing feature rankings.It reveals nonlinear thresholds and interaction effects that generate deeper mechanistic insights into hazard processes and mechanisms.Nevertheless,several key challenges remain unresolved within the field.These persistent issues are especially pronounced when considering the crucial necessity for interpretation stability,the demanding scholarly task of reliably distinguishing correlation from causation,and the development of appropriate methods for the treatment of complex spatio-temporal dynamics.
文摘Liver regeneration(LR)following partial hepatectomy(PH)is a unique and complex physiological response that restores hepatic mass and function through tightly orchestrated cellular and molecular events.Traditionally viewed as a proliferation-driven process,LR is now understood to involve both hepatocyte hyperplasia and hypertrophy,triggered primarily by hemodynamic alterations such as increased portal pressure and shear stress.These promote LR through endothelial–hepatocyte communication via activation of Piezo1-a mechanosensitive ion channel highly expressed in vascular endothelial cells.This channel is considered one of the potential upstream activators of molecular cascades including the interleukin(IL)-6/signal transducer and activator of transcription 3,tumour necrosis factor-alpha/nuclear factor-kappa B,Wnt/β-catenin,Hippo/YAP,transforming growth factor-beta,and Notch pathways,which contribute variably to the proliferation,differentiation,or suppression of hepatic cells.Novel insights into the IL-22 and IL-33 signaling axes,bile acid and glutamine metabolism,and the role of intestinal microbiota are also presented as promising emerging targets.This review synthesizes current insights into the interplay between mechanical cues,key signaling pathways,and metabolic reprogramming that govern early regenerative responses.We explore the mechanisms dictating the balance between hyperplasia and hypertrophy,noting that hypertrophy predominates after minor resections,while proliferation is dominant in larger resections.Polyploidization emerges as a significant adaptive mechanism,contributing to hepatocyte survival and tissue remodeling.The importance of ductular reactions,microvascular adjustments,and extracellular matrix dynamics in lobular architecture remodeling is also highlighted.The study explores the occurrence of ductular reactions in both minor and major resections,particularly within the granulation tissue near dissection areas.The paper also examines structural remodeling in regenerated liver tissue,demonstrating ongoing transformations in hepatocyte morphology and sinusoidal architecture even months after PH,and emphasizing that the termination of liver mass regrowth does not equate to the cessation of LR.
文摘Bruxism, characterized by involuntary clenching or grinding of teeth, affects approximately 10% - 20% of adults globally and has significant implications for dental and systemic health. Emerging AI-driven diagnostic tools have demonstrated a 25% improvement in identifying nocturnal bruxism compared to conventional methods. This study explores the etiology, pathogenesis, and treatment modalities of bruxism, integrating cutting-edge advancements like neuromodulation and personalized medicine. Furthermore, socioeconomic factors and access disparities are analyzed to propose comprehensive strategies for improving patient outcomes. Current management strategies include behavioral therapies, orthodontic appliances, pharmacological interventions, physical therapy, and, in severe cases, surgical options. Emerging technologies, such as artificial intelligence, personalized medicine, and neuromodulation, are highlighted as promising advancements in bruxism diagnosis and treatment. Additionally, the study underscores the socioeconomic and ethical dimensions of bruxism care, advocating for interdisciplinary collaboration, patient education, and equitable access to innovative treatments. This research aims to contribute to improved understanding and management of bruxism, enhancing patient outcomes and quality of life.
文摘BACKGROUND Living donor liver transplantation(LDLT)is a crucial alternative to deceased donor transplantation,especially in regions with limited access to cadaveric organs.Right lobe graft implantation into the inferior vena cava(IVC)requires advanced surgical techniques to optimize outcomes and reduce complications.AIM To compare two venous anastomosis techniques—direct polytetrafluoroethylene(PTFE)grafting of V5-V8 veins to the IVC vs triangulation to the right hepatic vein(RHV)—in terms of graft viability and postoperative outcomes.METHODS A retrospective analysis was conducted on 96 patients who underwent LDLT with right lobe grafts between 2014 and 2023.Patients were divided into three groups:(1)No venous outflow reconstruction;(2)PTFE graft direct anastomosis to the IVC;and(3)PTFE graft anastomosis using triangulation to the RHV.Perioperative and postoperative outcomes,including bile duct complications,alanine aminotransferase/aspartate aminotransferase levels,and graft perfusion,were compared across groups.RESULTS Group 3(triangulation to RHV)showed significantly improved venous outflow,fewer complications,and faster normalization of liver function tests.Bile duct complications were highest in group 1(12.8%)and lowest in group 3(7%).Doppler ultrasonography revealed better graft perfusion in group 3 compared to groups 1 and 2.CONCLUSION Triangulation to the RHV improves graft viability,reduces biliary complications,and enhances early postoperative outcomes compared to direct PTFE grafting to the IVC.
文摘BACKGROUND Obese patients(body mass index≥30 kg/m^(2))undergoing isolated aortic valve replacement(AVR)face increased surgical risks due to comorbidities.Partial upper sternotomy(PUS),a minimally invasive approach,may reduce complications compared to full median sternotomy(FMS).We hypothesize that PUS improves outcomes over FMS in obese patients undergoing AVR.AIM To compare the efficacy and safety of PUS vs FMS in obese patients undergoing isolated AVR.METHODS This systematic review and meta-analysis followed PRISMA guidelines,searching PubMed,EMBASE,and Cochrane databases for observational studies comparing PUS vs FMS in obese patients undergoing AVR.Outcomes were analyzed using odds ratios(OR),mean differences(MD),95%confidence intervals(CI),I^(2)statistic,and Newcastle-Ottawa Scale was used for quality assessment.RESULTS Four observational studies involving 677 patients were analyzed.PUS reduced intensive care unit stay(MD-2.67 days,95%CI:-4.43 to-0.90,P=0.003,I^(2)=78%)but increased cardiopulmonary bypass time(MD 5.62 minutes,95%CI:-0.36 to 11.59,I^(2)=55%).No differences were observed in renal failure(OR 1.13,95%CI:0.63-2.94,I^(2)=0%),atrial fibrillation(OR 0.81,95%CI:0.43-1.54,I^(2)=30%),reexploration(OR 1.09,95%CI:0.48-2.47,I^(2)=0%),postoperative bleeding(OR 1.48,95%CI:0.53-4.15,I^(2)=60%),wound infection(OR 1.23,95%CI:0.70-2.14,I^(2)=0%),hospital stay(MD 0.51 days,95%CI:-4.13 to 5.15,I^(2)=90%),or cross-clamp time(MD 4.03 minutes,95%CI:-0.75 to 8.80,I^(2)=50%).CONCLUSION PUS is safe and effective for obese patients undergoing AVR,reducing intensive care unit stay and enhancing recovery,provided surgical expertise is available.
基金supported by projects VEGA 1/0307/23 and APVV-23-0204 of Scientific Grant Agency of the Ministry of Education,Research,Development and Youth of the Slovak Republic.
文摘The undercurrent research survey explores the roles of nonlocality and strain gradient size dependencies in nonlinear asymmetric buckling of shallow nanoscale arches having dissimilar end conditions through a numerical analysis.The arches,made from a functionally graded graphene nanofiller reinforced composite(FG-GNRC),are subjected to discretional radial concentrated loads along with converting of temperature.To account for the size dependencies,the exploration is carried out stemming from the nonlocal strain gradient theory(NSGT)in the sense of a quasi-2D parabolic shear flexible concept of curved beam.The material properties of the contemplated FG-GNRC sandwich are determined using the modified Halpin-Tsai micromechanics model.Subsequently,an extended isogeometric analysis(XIGA)is manipulated comprising insertion plus multiplication of knots to achieve the demanded lower continuity allocated to the integration between flexural and tangential reflexes.It is perceived that the both softening and stiffening concomitants assigned to the salient concentrated radial loads obtained by the developed NSGT-based XIGA diminish from the first upper limit to the second one,and then likewise from the first lower limit to the second one.Although,by becoming the upsurge in temperature higher,these softening and stiffening concomitants get more remarkable.
基金the support from the National Natural Science Foundation of China(NSFC)under Grant Nos.12322502 and 12335002the Joint Large Scale Scientific Facility Funds of the NSFC and Chinese Academy of Sciences(CAS)under Contract No.U1932110+3 种基金the Hunan Provincial Natural Science Foundation under Grant No.2024JJ3004the Fundamental Research Funds for the central universitiessupported by the CAS President’s International Fellowship Initiative(PIFI)(Grant No.2025PD0022)by the MKW NRW under the funding code No.NW21-024-A and by ERC AdG EXOTIC(Grant No.101018170)。
文摘We review recent experimental and theoretical results for the electromagnetic form factors of hyperons(Y)in the timelike region,accessible in the reactions e^(+)e^(-)→YY.Specifically,we focus on the final statesΛΛ,ΛΣ^(0)/Λ,Σ^(0)Λ,■■,andΩΩ.TheΛ_(c)Λ_(c)system is also discussed.
文摘Objective:To assess the level of nursing students’knowledge about delirium and its associated risk factors.Delirium is a clinical syndrome characterized by alterations in cognition and psychomotor activity.Since delirium is common among geriatric patients,adequate preparedness of nursing students to assess and manage delirious geriatric patients is necessary to improve potential nurses’quality of care and communication with this group.Limited research work was conducted to address nursing students’knowledge about delirium.Methods:This cross-sectional descriptive study was conducted from October 2022 to February 2023.A convenience sampling was used,and 319 valid questionnaires were obtained from nursing students from six Jordanian governmental and private universities,who were at least in their third academic year.An adopted delirium knowledge scale was used to collect data.Descriptive statistics and an independent t-test were used for data analysis.Results:The mean for general knowledge about delirium was 57.5%.The mean for knowledge of delirium risk factors was 61.8%.Nursing students in their fourth academic year scored significantly higher on both general knowledge and risk knowledge scales than students in the third academic year.Conclusions:Nursing students’knowledge regarding delirium and its risk factors was low.Educational efforts should be maximized for incorporating and addressing the topic of delirium in the undergraduate nursing curriculum.Implications of this study include revising nursing curricula to ensure that students receive enough education on delirium,including its detection,diagnosis,and management.The implications also include giving nursing students the chance to gain experience in caring for delirious patients and providing them with the tools and resources they need to assess and manage delirium.
基金supported by the National Natural Science Foundation of China(52350410465)the General Projects of Guangdong Natural Science Research Projects(2023A1515011520).
文摘Accurate daily suspended sediment load(SSL)prediction is essential for sustainable water resource management,sediment control,and environmental planning.However,SSL prediction is highly complex due to its nonlinear and dynamic nature,making traditional empirical models inadequate.This study proposes a novel hybrid approach,integrating the Adaptive Neuro-Fuzzy Inference System(ANFIS)with the Gradient-Based Optimizer(GBO),to enhance SSL forecasting accuracy.The research compares the performance of ANFIS-GBO with three alternative models:standard ANFIS,ANFIS with Particle Swarm Optimization(ANFIS-PSO),and ANFIS with Grey Wolf Optimization(ANFIS-GWO).Historical SSL and streamflow data from the Bailong River Basin,China,are used to train and validate the models.The input selection process is optimized using the Multivariate Adaptive Regression Splines(MARS)method.Model performance is evaluated using statistical metrics such as Root Mean Square Error(RMSE),Mean Absolute Error(MAE),Mean Absolute Percentage Error(MAPE),Nash Sutcliffe Efficiency(NSE),and Determination Coefficient(R^(2)).Additionally,visual assessments,including scatter plots,Taylor diagrams,and violin plots,provide further insights into model reliability.The results indicate that including historical SSL data improves predictive accuracy,with ANFIS-GBO outperforming the other models.ANFIS-GBO achieves the lowest RMSE and MAE and the highest NSE and R^(2),demonstrating its superior learning ability and adaptability.The findings highlight the effectiveness of nature-inspired optimization algorithms in enhancing sediment load forecasting and contribute to the advancement of AI-based hydrological modeling.Future research should explore the integration of additional environmental and climatic variables to enhance predictive capabilities further.
文摘Water quality is always one of the most important factors in human health. Artificial intelligence models are respected methods for modeling water quality. The evolutionary algorithm (EA) is a new technique for improving the performance of artificial intelligence models such as the adaptive neuro fuzzy inference system (ANFIS) and artificial neural networks (ANN). Attempts have been made to make the models more suitable and accurate with the replacement of other training methods that do not suffer from some shortcomings, including a tendency to being trapped in local optima or voluminous computations. This study investigated the applicability of ANFIS with particle swarm optimization (PSO) and ant colony optimization for continuous domains (ACOR) in estimating water quality parameters at three stations along the Zayandehrood River, in Iran. The ANFIS-PSO and ANFIS-ACOR methods were also compared with the classic ANFIS method, which uses least squares and gradient descent as training algorithms. The estimated water quality parameters in this study were electrical conductivity (EC), total dissolved solids (TDS), the sodium adsorption ratio (SAR), carbonate hardness (CH), and total hardness (TH). Correlation analysis was performed using SPSS software to determine the optimal inputs to the models. The analysis showed that ANFIS-PSO was the better model compared with ANFIS-ACOR. It is noteworthy that EA models can improve ANFIS' performance at all three stations for different water quality parameters.
文摘The article considers the variability of Nenskra and Nakra River basins glaciers’ parameters in the years of 1911-2014. Nenskra and Nakra River basins are located on the southern slope of the Great Caucasus, between the Kharikhra, Shdavleri and Tsalgmili ranges, in Georgia, in particular in the Enguri River basin. In our research we used the catalogue of the glaciers of Georgia compiled by K. Podozerskiy in 1911. We also used the military topographic maps with the scale of 1:25,000 and 1:50,000 drawn up in 1960 (in former Soviet Union), where there are the glaciers mapped in detail and the ends of their ice tongues on the southern slope of Great Caucasus of those times. We also used the remote sensing method, which is the best modern way for the study of the dynamics of glaciers and this method is remarkable by a quick obtaining of results. The spectral images of the Landsat L8 OLI/TIRS (Operational Land Imager and Thermal Infrared Sensor) (USGS) received from the “Landsat” artificial satellite are the necessary materials for our study. We also used the field survey materials of 2014 (GPS data). The latest statistical information is also given about the glaciers located in the individual river basins;their morphological types, exposition and the dynamics are considered according to the individual years.
文摘The rapid propagation of multidrug resistant bacterial strains is leading to renewed interest in bacteriophage therapy.With challenges in the treatment of bacterial infections,it is essential for people worldwide to understand how alternative approaches,such as bacteriophages,could be used to combat antibiotic resistant bacteria.The Eliava Institute
文摘Phanerozoic geodynamic development of the Tethys ocean revealed at Eurasian active margin is manifested in pre-and post-collision stages.The Phanerozoic crust was already divided into sialic and basaltic crusts and rigid upper mantle.The precious and nonferrous metals were redistributed between them.In the sialic crust,precious metals are concentrated: Au,Ag and Pb,in basaltic crust—zinc,the copper mainly rests in the mantle.Phanerozoic plate-tectonics was manifested in the following settings: island arc,inter/backarc and oceanic.Island arc setting correlates with steady-state subduction and controlled by calc-alkaline volcanism.At this stage,the sialic,basaltic crust and mantle material participate in volcanism,whereas the subducted slab plunged in mantle,the metallogenic indicators are Au,Pb,Zn and Cu.The stage of inter/backarc is related to steepening of subducting slab,because mantle diapir incursion provokes the rifting.At the initial stage and at stage of slackening rifting,when the sialic crust is not yet spread out from zone of volcanic activity,mineralization was represented by subalkaline trachydacites,shoshonite and alkali basaltic volcanism(volcanological indicators)and Au and Pb are participated with Zn and Cu in mineralization.The strengthening of steepening with mantle diapir incursion on higher level rifting spread out the sialic crust,volcanism on this stage is tholeiitic and mineralization is represented by zinc-copper-pyrite VMS(Volcanogenic Massive Sulphide)ores.The minor ocean setting is controlled by the most intensive spreading provoked by incursion mantle diapir at highest level,and spread out the basaltic crust as well,and volcanism belongs to ophiolites with dunite-peridotite magmatic activity.The mineralization was represented by copper-pyrite ores and single metallogenic indicator is the copper.The convergence of Eurasian and Afro-Arabian continents and closing of Tethys Ocean resulted in transferring the pre-collision stage in post-collision,characterized by trace elements Sb,W,Mo,Hg,as geochemical and metallogenic indicator of the postcollision setting.
文摘The given article presents an analytical model developed for a multichannel technical queuing system with time redundancy for operability management, subsystems of reliable periodical control of sudden and gradual failure detection and a subsystem for system recovery after failure. It is assumed in the model that the failures are governed by the Poisson probability distribution law and the times of reliable control and system recovery after failures are governed by an arbitrary law of probability distribution, in the general case depending on the number of servicers. The paper defines probabilities of accomplishment of certain task volumes by the system within a priori defined time intervals, taking into consideration its reliability characteristics.
基金supported by project TMOP-4.2.2.A-11/1/KONV-2012-0051,Shota Rustaveli National Science Foundation grant no.13/06(Geometry of function spaces,interpolation and embedding theorems)
文摘The main aim of this article is to prove that the maximal operator σ^k* of the Marcinkiewicz-Fejer means of the two-dimensional Fourier series with respect to Walsh- Kaczmarz system is bounded from the Hardy space H2/3 to the space weak-L2/3.