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Methods for separating the noise produced by the wheels and track during a train pass‑by
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作者 David Thompson Dong Zhao +4 位作者 Giacomo Squicciarini Martin Toward Ester Cierco Erwin Jansen Michael Dittrich 《Railway Engineering Science》 2025年第3期342-358,共17页
Rolling noise is produced by vibration of the wheels and track,induced by their combined surface roughness.It is important to know the relative contributions of the different sources,as this affects noise control stra... Rolling noise is produced by vibration of the wheels and track,induced by their combined surface roughness.It is important to know the relative contributions of the different sources,as this affects noise control strategies as well as acceptance testing of new rolling stock.Three different techniques are described that aim to use pass-by measurements to separate the wheel and track components of rolling noise.One is based on the TWINS model,which is tuned to measured track vibration.The second is based on the advanced transfer path analysis method,which provides an entirely experimental assessment.The third is based on the pass-by analysis method in combination with static vibroacoustic transfer functions which are obtained using a reciprocity method.The development of these methods is described and comparisons between them are presented using the results from three experimental measurement campaigns.These covered a metro train,a regional train and a high-speed train at a range of speeds.The various methods agree reasonably well in terms of overall trends,with moderate agreement in the mid-frequency region,and less consistent results at low and high frequency. 展开更多
关键词 Railway noise Rolling noise Source separation Pass-by tests
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Reply to the note by Li Piani et al. 被引量:1
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作者 T.Li Piani J.Weerheijm L.J.Sluys 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2024年第1期603-606,共4页
In 2017,a ballistic phenomenological model was proposed by the authors of Ref.[1] to numerically simulate the experimental depths of small caliber projectiles impacting walls made of adobe.The opportunity for a new mo... In 2017,a ballistic phenomenological model was proposed by the authors of Ref.[1] to numerically simulate the experimental depths of small caliber projectiles impacting walls made of adobe.The opportunity for a new model in the field revealed from the observation that two older models recently used by the authors of Ref.[2] shared a linear relationship between the penetration depth P and the impacting velocity v_(O). 展开更多
关键词 PENETRATION ADOBE Modeling
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The influence of reflections from the train body and the ground on the sound radiation from a railway rail 被引量:1
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作者 David J.Thompson Dong Zhao +3 位作者 Evangelos Ntotsios Giacomo Squicciarini Ester Cierco Erwin Jansen 《Railway Sciences》 2024年第1期1-17,共17页
Purpose – The vibration of the rails is a significant source of railway rolling noise, often forming the dominantcomponent of noise in the important frequency region between 400 and 2000 Hz. The purpose of the paper ... Purpose – The vibration of the rails is a significant source of railway rolling noise, often forming the dominantcomponent of noise in the important frequency region between 400 and 2000 Hz. The purpose of the paper is toinvestigate the influence of the ground profile and the presence of the train body on the sound radiation fromthe rail.Design/methodology/approach – Two-dimensional boundary element calculations are used, in which therail vibration is the source. The ground profile and various different shapes of train body are introduced in themodel, and results are observed in terms of sound power and sound pressure. Comparisons are also made withvibro-acoustic measurements performed with and without a train present.Findings – The sound radiated by the rail in the absence of the train body is strongly attenuated by shieldingdue to the ballast shoulder. When the train body is present, the sound from the vertical rail motion is reflectedback down toward the track where it is partly absorbed by the ballast. Nevertheless, the sound pressure at thetrackside is increased by typically 0–5 dB. For the lateral vibration of the rail, the effects are much smaller. Oncethe sound power is known, the sound pressure with the train present can be approximated reasonably well withsimple line source directivities.Originality/value – Numerical models used to predict the sound radiation from railway rails have generallyneglected the influence of the ground profile and reflections from the underside of the train body on the soundpower and directivity of the rail. These effects are studied in a systematic way including comparisons with measurements. 展开更多
关键词 Rolling noise Sound radiation Railway track Boundary elements Ground reflections DIRECTIVITY
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A two-scale method to include essential behaviour of bolted connections instructures including elevated temperatures
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作者 Qingfeng Xu Hèrm Hofmeyer Johan Maljaars 《Theoretical & Applied Mechanics Letters》 CSCD 2024年第6期496-512,共17页
A two-scale method is proposed to simulate the essential behavior of bolted connections in structures includingelevated temperatures.It is presented,verified,and validated for the structural behavior of two plates,con... A two-scale method is proposed to simulate the essential behavior of bolted connections in structures includingelevated temperatures.It is presented,verified,and validated for the structural behavior of two plates,connectedby a bolt,under a variety of loads and elevated temperatures.The method consists of a global-scale model thatsimulates the structure(here the two plates)by volume finite elements,and in which the bolt is modelled bya spring.The spring properties are provided by a smallscale model,in which the bolt is modelled by volumeelements,and for which the boundary conditions are retrieved from the global-scale model.To ensure the small-scale model to be as computationally efficient as possible,simplifications are discussed regarding the materialmodel and the modelling of the threads.For the latter,this leads to the experimentally validated application ofa non-threaded shank with its stress area.It is shown that a non-linear elastic spring is needed for the bolt inthe global-scale model,so the post-peak behavior of the structure can be described efficiently.All types of boltedconnection failure as given by design standards are simulated by the twoscale method,which is successfullyvalidated(except for net section failure)by experiments,and verified by a detailed system model,which modelsthe structure in full detail.The sensitivity to the size of the part of the plate used in the small-scale modelis also studied.Finally,multi-directional load cases,also for elevated temperatures,are studied with the two-scale method and verified with the detailed system model.As a result,a computationally efficient finite elementmodelling approach is provided for all possible combined load actions(except for nut thread failure and netsection failure)and temperatures.The two-scale method is shown to be insightful,for it contains a functionalseparation of scales,revealing their relationships,and consequently,local small-scale non-convergence can behandled.Not presented in this paper,but the two-scale method can be used in e.g.computationally expensive two-way coupled fire-structure simulations,where it is beneficial for distributed computing and densely packed boltconfigurations with stiffplates,for which a single small-scale model may be representative for several connections. 展开更多
关键词 Two-scale method Finite element model Bolted connection Structural failure Elevated temperatures FIRE
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正面碰撞安全带约束系统开发与试验验证 被引量:44
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作者 张学荣 刘学军 +1 位作者 陈晓东 苏清祖 《汽车工程》 EI CSCD 北大核心 2007年第12期1055-1058,共4页
详细介绍MADYMO安全带及正面碰撞模型的建模流程;并利用此模型,从乘员运动姿态、头胸部伤害响应值和非约束系统效率等方面,对比不同安全带预紧器、限力器模型对乘员的保护效果。计算结果表明,利用预紧器消除安全带的初始松弛量,可显著... 详细介绍MADYMO安全带及正面碰撞模型的建模流程;并利用此模型,从乘员运动姿态、头胸部伤害响应值和非约束系统效率等方面,对比不同安全带预紧器、限力器模型对乘员的保护效果。计算结果表明,利用预紧器消除安全带的初始松弛量,可显著提高乘员的非约束系统效率,并有效降低人体损伤值;在预紧量相同的情况下,锁扣预紧器的非约束系统效率优于卷收器预紧器;利用限力器可减轻胸部载荷。 展开更多
关键词 安全带 约束系统 预紧器 限力器 验证
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肌肉骨骼疾患调查表介绍附调查表 被引量:230
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作者 杨磊 VH. Hildebrandt +7 位作者 余善法 凌瑞杰 何丽华 陈卫红 夏昭林 王建新 李丽萍 王生 《工业卫生与职业病》 CAS CSCD 北大核心 2009年第1期25-31,共7页
关键词 肌肉骨骼疾患 调查表 工作有关疾病 国际劳工组织 职业卫生问题 职业安全卫生 职业人群 颈肩综合征
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正面碰撞不同身材乘员保护约束系统的设计 被引量:10
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作者 张学荣 刘学军 苏清祖 《汽车工程》 EI CSCD 北大核心 2007年第8期669-672,共4页
重点研究对50百分位男性乘员实现最有保护的约束系统,应用到5百分位女性乘员和95百分位男性乘员情况下的保护效果,并针对存在的问题提出可根据乘员的身材调整气囊排气孔的面积、座椅安全带限力器水平的智能约束系统,设计了吸能压溃式转... 重点研究对50百分位男性乘员实现最有保护的约束系统,应用到5百分位女性乘员和95百分位男性乘员情况下的保护效果,并针对存在的问题提出可根据乘员的身材调整气囊排气孔的面积、座椅安全带限力器水平的智能约束系统,设计了吸能压溃式转向柱,对不同身材乘员的保护效果进行了评价。 展开更多
关键词 正面碰撞 乘员身材 约束系统 开发
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交替半身照射消除体内残留白血病细胞的实验研究 被引量:16
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作者 褚建新 A.C.M.Martens +2 位作者 阎影 D.W.VanBekkum A.Hagenbeek 《中国医学科学院学报》 CAS CSCD 北大核心 1993年第1期12-16,共5页
用BN大鼠粒细胞白血病模型(BNML),于白血病强化疗后交替进行半身照射,不用骨髓移植,以代替全身照射移植自身骨髓。结果表明,实验动物能耐受这一新的治疗措施,骨髓造血能自行重建,无1只大鼠死于造血衰竭,而且实验动物生存时间比单用化疗... 用BN大鼠粒细胞白血病模型(BNML),于白血病强化疗后交替进行半身照射,不用骨髓移植,以代替全身照射移植自身骨髓。结果表明,实验动物能耐受这一新的治疗措施,骨髓造血能自行重建,无1只大鼠死于造血衰竭,而且实验动物生存时间比单用化疗动物明显延长。 展开更多
关键词 白血病 交替半身照射 放射疗法
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HPLC/LTQ-FTMS用于白参中的丙二酰基人参皂苷的研究 被引量:6
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作者 孔宏伟 王梅 +3 位作者 Rob van der Heijden Jan van der Greef Thomas Hankemeier 许国旺 《世界科学技术-中医药现代化》 2009年第1期190-194,共5页
在15mM甲酸铵作为流动相添加剂条件下,采用HPLC/LTQ-FTMS实现了白参样品中酸性人参皂苷的优化分离。根据高分辨质谱、多级质谱信息,结合保留规律验证,在白参萃取液中共检测和识别了八种丙二酰基人参皂苷,包括丙二酰基人参皂苷Rg1、Re、R... 在15mM甲酸铵作为流动相添加剂条件下,采用HPLC/LTQ-FTMS实现了白参样品中酸性人参皂苷的优化分离。根据高分辨质谱、多级质谱信息,结合保留规律验证,在白参萃取液中共检测和识别了八种丙二酰基人参皂苷,包括丙二酰基人参皂苷Rg1、Re、Rf、Rb1、Rc、Rb2、Rb3和Rd。 展开更多
关键词 HPLC/LTQ—FTMS 丙二酰基人参皂苷 白参 甲酸铵
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逆转录病毒介导的标志性基因在哺乳类白血病细胞林中的基因转移 被引量:1
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作者 阎影 丁训杰 +2 位作者 ACHMartens DWvanBekkum HagenbeekA 《肿瘤》 CAS CSCD 北大核心 1991年第3期119-122,共4页
白血病微小残留疾病(MRD)做为白血病诱导治疗缓解后的一个特定阶段,患者体内仍残留白血病细胞群体,然而常规方法难于检测和判断体内白血病细胞的数量与分布。急性粒细胞性白血病BN(Brown Norway)大鼠模型(BNML)作为对比性研究人类急性... 白血病微小残留疾病(MRD)做为白血病诱导治疗缓解后的一个特定阶段,患者体内仍残留白血病细胞群体,然而常规方法难于检测和判断体内白血病细胞的数量与分布。急性粒细胞性白血病BN(Brown Norway)大鼠模型(BNML)作为对比性研究人类急性粒细胞白血病的动物模型,对了解急性白血病微小残留疾病的生物学特征提供了重要的帮助。在BNML中采用包括流式细胞仪(FACS)等不同方法检测MRD,费时较多,或者不够敏感。 展开更多
关键词 白血病 逆转录病毒 基因转移
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Dietary Fibres and Whole Grain Products for Improving Health and Reducing Disease Risks 被引量:10
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作者 Jan Willem van der Kamp 《食品科学》 EI CAS CSCD 北大核心 2004年第10期421-422,共2页
关键词 食物纤维 谷类产品 保健 营养
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Connect & Drive:design and evaluation of cooperative adaptive cruise control for congestion reduction 被引量:10
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作者 Jeroen PLOEG Alex F.A.SERRARENS Geert J.HEIJENK 《Journal of Modern Transportation》 2011年第3期207-213,共7页
Road throughput can be increased by driving at small inter-vehicle time gaps. The amplification of velocity disturbances in upstream direction, however, poses limitations to the minimum feasible time gap. This effect ... Road throughput can be increased by driving at small inter-vehicle time gaps. The amplification of velocity disturbances in upstream direction, however, poses limitations to the minimum feasible time gap. This effect is covered by the notion of string stability. String-stable behavior is thus considered an essential requirement for the design of automatic distance control systems, which are needed to allow for safe driving at time gaps well below 1 s. Using wireless inter-vehicle communications to provide real-time information of the preceding vehicle, in addition to the information obtained by common Adaptive Cruise Control (ACC) sensors, appears to significantly decrease the feasible time gap, which is shown by practical experiments with a test fleet consisting of six passenger vehicles. The large-scale deployment of this system, known as Cooperative ACC (CACC), however, poses challenges with respect to the reliability of the wireless communication system. A solution for this scalability problem can be found in decreasing the transmission power and/or beaconing rate, or adapting the communications protocol. Although the main CACC objective is to increase road throughput, the first commercial application of CACC is foreseen to be in truck platooning, since short distance following is expected to yield significant fuel savings in this case. 展开更多
关键词 cooperative adaptive cruise control (CACC) string stability cooperative driving traffic congestion fuel efficiency
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Acoustic measurements of models of military style supersonic nozzle jets 被引量:3
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作者 Ching-Wen Kuo Jérémy Veltin Dennis K.McLaughlin 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2014年第1期23-33,共11页
Modern military aircraft jet engines are designed with variable-geometry nozzles to provide optimal thrust in different operating conditions, depending on the flight envelope. How- ever, acoustic measurements for such... Modern military aircraft jet engines are designed with variable-geometry nozzles to provide optimal thrust in different operating conditions, depending on the flight envelope. How- ever, acoustic measurements for such nozzles are scarce, due to the cost involved in making full- scale measurements and the lack of details about the exact geometries of these nozzles. Thus the present effort at Pennsylvania State University (PSU) in partnership with GE Aviation and the NASA Glenn Research Center is aiming to study and characterize the acoustic field produced by supersonic jets issuing from converging-diverging military style nozzles, and to identify and test promising noise reduction techniques. An equally important objective is to develop methodology for using data obtained from small- and moderate-scale experiments to reliably predict the full-scale engine noise. The experimental results presented show reasonable agreement between small-scale and medium-scale jets, as well as between heated jets and heat-simulated ones. 展开更多
关键词 Aeroacoustics Acoustic noise measurement Jet noise Jets NOZZLE Supersonic flow
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用于设计和评估汽车主动安全及一体化安全系统的开发方法(英文) 被引量:3
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作者 MartijnTIDEMAN ThijsVERSTEEGH +1 位作者 RoyBOURS XuejunLIU 《汽车安全与节能学报》 CAS 2012年第2期116-122,共7页
汽车主动安全和一体化安全系统的开发复杂且费时。荷兰国家应用科学研究院(TNO)发明了一种基于仿真工具和测试设备的无缝结合,用于设计和评估主动安全及一体化安全系统的新方法,以保证开发流程的有效性和高效率。该方法使用的主要工具包... 汽车主动安全和一体化安全系统的开发复杂且费时。荷兰国家应用科学研究院(TNO)发明了一种基于仿真工具和测试设备的无缝结合,用于设计和评估主动安全及一体化安全系统的新方法,以保证开发流程的有效性和高效率。该方法使用的主要工具包括:PreScan软件、VeHIL试验室和MADYMO软件。该方法将真实生活中的事故统计数据和用户需求转换成系统设计,进而预测真实生活的事故发生率和损伤等级。试验结果已被用来验证仿真模型。经过验证的仿真模型,可用于设计和测试系统,预测系统在真实生活中的作用效果,定义最终验证该系统所需的试验矩阵。案例演示了如何将这些工具一起应用于主动安全及一体化安全系统的开发流程中。 展开更多
关键词 汽车安全 主动安全 一体化安全 开发方法 开发工具 真实生活安全
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Geomechanical effects of CO_2 storage in depleted gas reservoirs in the Netherlands:Inferences from feasibility studies and comparison with aquifer storage 被引量:2
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作者 Bogdan Orlic 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2016年第6期846-859,共14页
In this paper,the geomechanical impact of large-scale carbon dioxide(CO) storage in depleted Dutch gas fields is compared with the impact of COstorage in saline aquifers.The geomechanical behaviour of four potential C... In this paper,the geomechanical impact of large-scale carbon dioxide(CO) storage in depleted Dutch gas fields is compared with the impact of COstorage in saline aquifers.The geomechanical behaviour of four potential COstorage sites is examined using flow and geomechanical simulations.Many gas reservoirs in the Netherlands are found in fault blocks,one to a few kilometres wide,laterally bounded by sealing faults.Aquifer depletion or re-pressurization in the lateral direction is seldom an issue because of a lack of active aquifers.Reservoir pressure changes are therefore limited to a gas-bearing fault block,while the induced stress changes affect the gas reservoir and extend 1-3 km away into the surrounding rock.Arguments in favour of COstorage in depleted gas fields are:proven seal quality,availability of field data,no record of seal integrity failure by fault reactivation from the seismically active producing Dutch gas fields,and the potential benefits of restoring the virgin formation pressure and stress state to geomechanical stability.On the other hand,COinjection in saline aquifers causes pressure build-up that exceeds the virgin hydrostatic pressure.Stress perturbations resulting from pressure build-up affect large areas,extending tens of kilometres away from the injection wells.Induced stresses in top seals are.however,small and do not exceed a few tenths of megapascal for a pressure build-up of a few megapascals in the storage formation.Geomechanical effects on top seals are weak,but could be enhanced close to the injection zone by the thermal effects of injection.Uncertainties related to characterisation of large areas affected by pressure build-up are significant,and seal quality and continuity are more difficult to be demonstrated for aquifers than for depleted gas reservoirs that have held hydrocarbons for millions of years. 展开更多
关键词 Carbon dioxide(CO_2) injection CO_2 storage Geomechanics of CO_2 storage Geomechanical modelling
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基于模型控制的未来柴油机开发(英文) 被引量:2
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作者 Hommen G. +9 位作者 Ramachandran S. Ramesh S. Feru E. Seykens X. Willems F. 《汽车技术》 CSCD 北大核心 2017年第9期7-19,共13页
Heavy duty diesel vehicles compliant with current Euro VI/EPA13 emission limits employ aftertreatment systems based on DOC/DPF technology for soot and particulate matter reduction and SCR catalysts with urea dosing fo... Heavy duty diesel vehicles compliant with current Euro VI/EPA13 emission limits employ aftertreatment systems based on DOC/DPF technology for soot and particulate matter reduction and SCR catalysts with urea dosing for NO x reduction. Traditionally, the majority of the control systems used for urea dosing are map based. However, increasing system complexity combined with real-world performance requirements are a strong motivation to switch to a model-based control approach. Firstly, this article describes a model-based design approach for aftertreatment control development. Focus is on urea dosing control for Euro VI level SCR systems. To achieve the legal emissions limits, including in-service conformity over the vehicle lifetime, advanced model-based control strategies enable maximal NO x conversion in combination with minimum ammonia slip, while ensuring robustness against real-life disturbances. Simulation and experimental results of the control system are presented, which demonstrate the performance and robustness properties. Following this model-based approach, a concept study is performed to explore aftertreatment and control technologies to achieve ultra-low NO x emissions as will be imposed by regulatory bodies in the near future. It is shown that aftertreatment concepts with Passive NO x Adsorber and SCR on DPF are most promising. To optimize overall engine-aftertreatment performance, the modelbased control approach is extended towards Integrated Emission Management(IEM). Based on the actual system state, this supervisory controller minimizes operating costs at each instant in time under all operating conditions. This is key for costoptimal and robust performance. 展开更多
关键词 柴油车 环境保护 环境管理 控制系统
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Insights into the radial water jet drilling technology-Application in a quarry 被引量:4
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作者 Thomas Reinsch Bob Paap +2 位作者 Simon Hahn Volker Wittig Sidney van den Berg 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2018年第2期236-248,共13页
In this context, we applied the radial water jet drilling(RJD) technology to drill five horizontal holes into a quarry wall of the Gildehaus quarry close to Bad Bntheim, Germany. For testing the state-of-the-art jetti... In this context, we applied the radial water jet drilling(RJD) technology to drill five horizontal holes into a quarry wall of the Gildehaus quarry close to Bad Bntheim, Germany. For testing the state-of-the-art jetting technology, a jetting experiment was performed to investigate the influence of geological heterogeneity on the jetting performance and the hole geometry, the influence of nozzle geometry and jetting pressure on the rate of penetration, and the possibility of localising the jetting nozzle utilizing acoustic activity. It is observed that the jetted holes can intersect fractures under varying angles, and the jetted holes do not follow a straight path when jetting at ambient surface condition. Cuttings from the jetting process retrieved from the holes can be used to estimate the reservoir rock permeability. Within the quarry, we did not observe a change in the rate of penetration due to jetting pressure variations.Acoustic monitoring was partially successful in estimating the nozzle location. Although the experiments were performed at ambient surface conditions, the results can give recommendations for a downhole application in deep wells. 展开更多
关键词 Acoustic monitoring Drilling performance TRAJECTORY PERMEABILITY Rock properties Radial water jet drilling(RJD)
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Ballistic model for the prediction of penetration depth and residual velocity in adobe:A new interpretation of the ballistic resistance of earthen masonry 被引量:2
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作者 T.Li Piani J.Weerheijm L.J.Sluys 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2018年第5期607-611,共5页
In this paper, a new one-dimensional phenomenological model is developed for the assessment of the ballistic performance of Adobe. Adobe is a masonry largely spread in areas of the world involved in military operation... In this paper, a new one-dimensional phenomenological model is developed for the assessment of the ballistic performance of Adobe. Adobe is a masonry largely spread in areas of the world involved in military operations. Addressing fundamental ballistic parameters such as residual velocity or penetration depth for this building technology is necessary. The model follows the hypotheses for the ballistic response of concrete targets to high velocity impacts, provided with a dominant contribution of shear friction typical of soils. The hypotheses at the basis of the model are consistent with all experimental evidence collected by authors on Adobe. Adobe brick and mortar belong to the material class of concrete,whereas the overall mechanical parameters are determined by the internal soil mixture, including the percentage of fibre reinforcement. Despite its relative simplicity, the model is capable of well predicting ballistic test results currently available in literature for Adobe, including the data of an experimental campaign recently performed by the authors on real Adobe walls in the field. 展开更多
关键词 Impact PENETRATION Depth Residual velocity ADOBE Wall BRICK MORTAR BALLISTIC
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服用抗氧化剂降低老年人血清脂质过氧化物——随机双盲临床试验 被引量:3
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作者 Matti Tolonen Seppo Sarna +6 位作者 Tuomas Westermarck Markku Halme Ulla-Riitta Nordberg Mirja Keinonen Jaap Schrijver Seppo E.J.Tuominen 杨旭冬 《营养学报》 CAS CSCD 北大核心 1989年第1期35-41,共7页
给某老年人护理院的45位老人服用β-胡萝卜素,维生素B_6,维生素C,维生素E,锌和硒,或者相应的安慰剂作为日常食物的补充,为期一年。开始时,这些老年人的血清脂质过氧化物水平(2.7±0.7μmol/L)高于作为对照组的年轻健康成年人(2.3... 给某老年人护理院的45位老人服用β-胡萝卜素,维生素B_6,维生素C,维生素E,锌和硒,或者相应的安慰剂作为日常食物的补充,为期一年。开始时,这些老年人的血清脂质过氧化物水平(2.7±0.7μmol/L)高于作为对照组的年轻健康成年人(2.3±0.6μmol/L),P<0.01。服药三个月后,老年人的血清脂质过氧化物已降至2.2±0.6μmol/L,并且保持这一低水平直到研究结束,而服安慰剂者血清脂质过氧化物无变化。 血清脂质过氧化物与全血硒浓度呈显著负相关(r=-0.428,P<0.01),但只有在血硒高于200μg/L时才可见血清脂质过氧化物的降低。血清α-维生素E浓度也与血清脂质过氧化物呈负相关,但相关程度(r=-0.273,P<0.76)低于与血硒间的相关。 从生物化学角度看,25%的老年人可观察到维生素B_6缺乏;每天补充2mg维生素B_6彻底治愈了全部的病例。服药组经几项心理学检验有轻微改善,而服用安慰剂的对照组无变化或者恶化。护士报告在服药组中见有临床改善,未见有毒性副作用。老年人服用抗氧化剂从生物化学和临床上都是有益的。 展开更多
关键词 抗氧化剂 血清脂质过氧化物 老年人
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Manipulation of the Bitcoin market:an agent-based study 被引量:1
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作者 Peter Fratrič Giovanni Sileno +1 位作者 Sander Klous Tom van Engers 《Financial Innovation》 2022年第1期1597-1625,共29页
Fraudulent actions of a trader or a group of traders can cause substantial disturbance to the market,both directly influencing the price of an asset or indirectly by misin-forming other market participants.Such behavi... Fraudulent actions of a trader or a group of traders can cause substantial disturbance to the market,both directly influencing the price of an asset or indirectly by misin-forming other market participants.Such behavior can be a source of systemic risk and increasing distrust for the market participants,consequences that call for viable countermeasures.Building on the foundations provided by the extant literature,this study aims to design an agent-based market model capable of reproducing the behavior of the Bitcoin market during the time of an alleged Bitcoin price manipulation that occurred between 2017 and early 2018.The model includes the mechanisms of a limit order book market and several agents associated with different trading strategies,including a fraudulent agent,initialized from empirical data and who performs market manipulation.The model is validated with respect to the Bitcoin price as well as the amount of Bitcoins obtained by the fraudulent agent and the traded volume.Simulation results provide a satisfactory fit to historical data.Several price dips and volume anomalies are explained by the actions of the fraudulent trader,completing the known body of evidence extracted from blockchain activity.The model suggests that the presence of the fraudulent agent was essential to obtain Bitcoin price development in the given time period;without this agent,it would have been very unlikely that the price had reached the heights as it did in late 2017.The insights gained from the model,especially the connection between liquidity and manipulation efficiency,unfold a discussion on how to prevent illicit behavior. 展开更多
关键词 Agent-based modelling Cryptocurrency Market manipulation LIQUIDITY Bitcoin
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