Herbicides are indispensable for safeguarding global crop production,yet their effectiveness is often undermined by extensive environmental losses during application.Using herbicide Diuron as a model compound,we devel...Herbicides are indispensable for safeguarding global crop production,yet their effectiveness is often undermined by extensive environmental losses during application.Using herbicide Diuron as a model compound,we developed hierarchical nanoparticles constructed through host-vip molecular recognition followed by electrostatic coassembly,yielding a formulation that unites high delivery efficiency with enhanced environmental compatibility.Relative to conventional wettable powders,these nanoparticles exhibited temperature-responsive release behavior and significantly enhanced foliar adhesion and deposition,increasing leaf retention by more than 241.7%.They also demonstrated strong resistance to rainfall wash-off and a markedly reduced propensity for groundwater leaching,with leaching losses decreased by approximately 18.6%.Greenhouse and field evaluations further confirmed their superior weed control under practical conditions,achieving control efficacies of up to 70.1%against Abutilon theophrasti and 52.9%against Setaria faberi,compared with 53.7%and 39.1%,respectively,for the commercial formulation at the same application rate.Extensive ecotoxicological assessments encompassing seed germination,zebrafish and earthworm assays,in vitro cellular tests,and in vivo rat studies consistently revealed an improved safety profile compared with commercial and technical formulations.Together,these results highlight hierarchical self-assembled nanoparticles as a promising platform for next-generation herbicide delivery that combines high target utilization with lower environmental impact and greater sustainability.展开更多
Poly(lactic acid)(PLA)has attracted considerable interest as an environmentally friendly and biodegradable polymer.The properties of poly(L-lactic acid)(PLLA)at an air/water interface were studied based on the Langmui...Poly(lactic acid)(PLA)has attracted considerable interest as an environmentally friendly and biodegradable polymer.The properties of poly(L-lactic acid)(PLLA)at an air/water interface were studied based on the Langmuir-Blodgett(LB)film balance and atomic force microscopy(AFM).The surface pressure-area(E-A)isotherm indicated that the surface pressure of PLLA initially increased as the interfacial film was compressed;at Tr=9.0 mN·m^-1,a plateau was observed in the TT--A isotherm,in which the area of the repeat unit was in the approximate range 0.11-0.17 nm^2,The AFM results showed that there is a clear structural transition in the PLLA film during the compression:(i)at the beginning of the plateau,a number of fibrils are present at the air/water interface and(ii)multilayer structures(at least bilayer,i.e.,the underlying layer and top layer consisting of fibrils)is formed in the plateau region.In particular,when Tr=20.0 mN·m^-1,a thin film of PLLA of thickness about 6.0 nm was fabricated.Our findings suggest that the plateau in the PLLA Tr-A isotherm is closely related to a change in the film structure from monolayer to multilayer at the air/water interface.This is significantly different from the behavior of conventional amphiphiles,because the plateau in amphiphiles TT--A isotherm is equivalent to a phase transition of monolayers derived from amphiphiles in a two-dimensional plane.展开更多
基金supported by the University Synergy Innovation Program of Anhui Province(GXXT-2021-059)the National Key Research and Development Program of China(2023YFD1702102)the Major Natural Science Research Project of Anhui Universities(2023AH040143).
文摘Herbicides are indispensable for safeguarding global crop production,yet their effectiveness is often undermined by extensive environmental losses during application.Using herbicide Diuron as a model compound,we developed hierarchical nanoparticles constructed through host-vip molecular recognition followed by electrostatic coassembly,yielding a formulation that unites high delivery efficiency with enhanced environmental compatibility.Relative to conventional wettable powders,these nanoparticles exhibited temperature-responsive release behavior and significantly enhanced foliar adhesion and deposition,increasing leaf retention by more than 241.7%.They also demonstrated strong resistance to rainfall wash-off and a markedly reduced propensity for groundwater leaching,with leaching losses decreased by approximately 18.6%.Greenhouse and field evaluations further confirmed their superior weed control under practical conditions,achieving control efficacies of up to 70.1%against Abutilon theophrasti and 52.9%against Setaria faberi,compared with 53.7%and 39.1%,respectively,for the commercial formulation at the same application rate.Extensive ecotoxicological assessments encompassing seed germination,zebrafish and earthworm assays,in vitro cellular tests,and in vivo rat studies consistently revealed an improved safety profile compared with commercial and technical formulations.Together,these results highlight hierarchical self-assembled nanoparticles as a promising platform for next-generation herbicide delivery that combines high target utilization with lower environmental impact and greater sustainability.
文摘Poly(lactic acid)(PLA)has attracted considerable interest as an environmentally friendly and biodegradable polymer.The properties of poly(L-lactic acid)(PLLA)at an air/water interface were studied based on the Langmuir-Blodgett(LB)film balance and atomic force microscopy(AFM).The surface pressure-area(E-A)isotherm indicated that the surface pressure of PLLA initially increased as the interfacial film was compressed;at Tr=9.0 mN·m^-1,a plateau was observed in the TT--A isotherm,in which the area of the repeat unit was in the approximate range 0.11-0.17 nm^2,The AFM results showed that there is a clear structural transition in the PLLA film during the compression:(i)at the beginning of the plateau,a number of fibrils are present at the air/water interface and(ii)multilayer structures(at least bilayer,i.e.,the underlying layer and top layer consisting of fibrils)is formed in the plateau region.In particular,when Tr=20.0 mN·m^-1,a thin film of PLLA of thickness about 6.0 nm was fabricated.Our findings suggest that the plateau in the PLLA Tr-A isotherm is closely related to a change in the film structure from monolayer to multilayer at the air/water interface.This is significantly different from the behavior of conventional amphiphiles,because the plateau in amphiphiles TT--A isotherm is equivalent to a phase transition of monolayers derived from amphiphiles in a two-dimensional plane.
