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Korea Institute of Sport Science:Past,Present and Future
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作者 Dong-Sik Chung 《中国体育科技》 CSSCI 北大核心 2009年第1期14-18,共5页
Introduction Korea Institute of Sport Science (KISS,formerly named as Korea Sport Science Institute:KSSI) was established on December 29th,1980 to perform research and provide support for better performance of the na... Introduction Korea Institute of Sport Science (KISS,formerly named as Korea Sport Science Institute:KSSI) was established on December 29th,1980 to perform research and provide support for better performance of the national athletes.KISS had clear objective of supporting scientifi c training of national athletes for successful hosting of 1986 Asian Games and 1988 Olympics,both were to be held in Seoul,Korea. The objective was successfully achieved with strong support from the government. 展开更多
关键词 运动员 体育训练 训练方法 科学训练
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Determination and Evaluation of the Self-Compassion Levels of the Students Studying in the Sport Sciences Faculties of Universities
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作者 Taner Yilmaz Elif Top Mustafa Akil 《Journal of Sports Science》 2016年第1期39-44,共6页
The present study has been conducted in order to determine the self-compassion levels of the students studying in various departments of the faculties of sports sciences and performing sports, and thus to find out whe... The present study has been conducted in order to determine the self-compassion levels of the students studying in various departments of the faculties of sports sciences and performing sports, and thus to find out whether certain variables such as their branch, department and families have an effect on their self-compassion levels. The "Self-compassion Scale" was used as the data collection tool in the study. In the present study, when the self-compassion levels of the students of the faculties of sports sciences were evaluated by various variables, it was found that the self-compassion levels of the students of Mugla University were significantly higher than those of the students of Ankara University, that the self-compassion levels of the students studying in the department of teaching were higher than those of the students studying in the department of coaching, and that the self-compassion levels of the students performing the branch of football were significantly higher than those of the students performing the branch of volleyball. When the students were compared based on the cities they live, it was found that the students living in the province of Mugla had significantly higher levels of self-compassion comparing to the students living in the province Ankara. Consequently, it was determined that the self-compassion levels of the students studying in various departments of the faculties of sports sciences were moderate, and that the differences in the province, department and the sports branch had an effect on the levels of self-compassion. 展开更多
关键词 SELF-COMPASSION EXERCISE physical education students.
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Response to the comment on"Does ischemic preconditioning enhance sports performance more than placebo or no intervention?A systematic review with meta-analysis"
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作者 Hiago L.R.Souza Géssyca T.Oliveira +5 位作者 Anderson Meireles Marcelo P.dos Santos Joao G.Vieira Rhai A.Arriel Stephen D.Patterson Moacir Marocolo 《Journal of Sport and Health Science》 2025年第5期134-135,共2页
We sincerely thank the authors of the commentary1 for their thoughtful analysis and constructive critique of our systematic review on ischemic preconditioning(IPC)and placebo effects in exercise capacity and athletic ... We sincerely thank the authors of the commentary1 for their thoughtful analysis and constructive critique of our systematic review on ischemic preconditioning(IPC)and placebo effects in exercise capacity and athletic performance.2Their attention to methodological details,particularly concerning the inclusion and timing of warm-up protocols across studies,is commendable and contributes meaningfully to the ongoing refinement of IPC research in sports science. 展开更多
关键词 meta analysis sports performance placebo effects PLACEBO ischemic preconditioning systematic review ischemic preconditioning ipc
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Promoting men's health through sports clubs:A systematic rapid realist review
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作者 Anne Timm Aurelie van Hoye +8 位作者 Paul Sharp Tue Helms Andersen Louise Hansen Jane NautrupØstergaard Peter Krustrup Kenneth Cortsen Peter Bindslev Iversen Morten Hulvej Rod Charlotte Demant Klinker 《Journal of Sport and Health Science》 2025年第1期84-96,共13页
Background Health promotion(HP)interventions delivered through sports clubs have demonstrated promising outcomes among men,but less is known about which aspects of the interventions work,for whom,and under what circum... Background Health promotion(HP)interventions delivered through sports clubs have demonstrated promising outcomes among men,but less is known about which aspects of the interventions work,for whom,and under what circumstances.This rapid realist review aimed to understand the contexts,mechanisms,and outcomes of HP interventions for men delivered through sports clubs.Methods A systematic literature search was conducted in February 2023 for studies published after 2013 in MEDLINE,Embase,and SPORTDiscus databases.Included studies:(a)were delivered by or in collaboration with sports clubs,(b)targeted men aged 18+years,and(c)reported 1 or more HP outcomes.A grey literature search was also performed.Studies were included in a realist synthesis based on richness and rigor.Hereafter,context-mechanism-outcome(CMO)configurations were developed.Results We identified and screened 3358 studies,finally including 59 studies describing 22 interventions.Most HP interventions were delivered in high income countries,included Caucasian men aged 35-65 years with overweight/obesity,and used professional sports clubs(mostly football)for recruitment and facilities.Quantitative HP outcomes were reported across 19 interventions.Of these 19 interventions,the majority reported on weight(n=18),physical activity(n=12),mental health(n=10),and diet(n=9).We identified 13 CMOs related to how HP interventions affected men's recruitment,engagement,and health behavior maintenance.Conclusion Our findings show that using sports clubs for HP interventions is effective for engaging men.Recruitment was facilitated by leveraging sports clubs’identity,addressing masculinity-related barriers,improving accessibility,and building trust.Engagement was enhanced through shared identity experiences,safe spaces,inclusive competition,and self-efficacy.However,there's limited evidence on behavior maintenance post-intervention,though involving community stakeholders seemed vital.In general,considerations should be made to avoid perpetuating traditional masculine norms,which may exclude some men and reinforce unhealthy behaviors.These findings can guide intervention development,emphasizing the need to harness men's perspectives in the process. 展开更多
关键词 Community engagement Health promotion MASCULINITY Physical activity Sports clubs
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Does ischemic preconditioning enhance sports performance more than placebo or no intervention?A systematic review with meta-analysis
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作者 Hiago L.R.Souza Géssyca T.Oliveira +5 位作者 Anderson Meireles Marcelo P.dos Santos Joao G.Vieira Rhai A.Arriel Stephen D.Patterson Moacir Marocolo 《Journal of Sport and Health Science》 2025年第2期21-34,共14页
Background:Ischemic preconditioning(IPC)is purported to have beneficial effects on athletic performance,although findings are inconsistent,with some studies reporting placebo effects.The majority of studies have inves... Background:Ischemic preconditioning(IPC)is purported to have beneficial effects on athletic performance,although findings are inconsistent,with some studies reporting placebo effects.The majority of studies have investigated IPC alongside a placebo condition,but without a control condition that was devoid of experimental manipulation,thereby limiting accurate determination of the IPC effects.Therefore,the aims of this study were to assess the impact of the IPC intervention,compared to both placebo and no intervention,on exercise capacity and athletic performance.Methods:A systematic search of PubMed,Embase,SPORTDiscus,Cochrane Library,and Latin American and Caribbean Health Sciences Literature(LILACS)covering records from their inception until July 2023 was conducted.To qualify for inclusion,studies had to apply IPC as an acute intervention,comparing it with placebo and/or control conditions.Outcomes of interest were performance(force,number of repetitions,power,time to exhaustion,and time trial performance),physiological measurements(maximum oxygen consumption,and heart rate),or perceptual measurements(RPE).For each outcome measure,we conducted 3 independent meta-analyses(IPC vs.placebo,IPC vs.control,placebo vs.control)using an inverse-variance random-effects model.The between-treatment effects were quantified by the standardized mean difference(SMD),accompanied by their respective 95%confidence intervals.Additionally,we employed the Grading of Recommendations,Assessment,Development and Evaluation(GRADE)approach to assess the level of certainty in the evidence.Results:Seventy-nine studies were included in the quantitative analysis.Overall,IPC demonstrates a comparable effect to the placebo condition(using a low-pressure tourniquet),irrespective of the subjects'training level(all outcomes presenting p>0.05),except for the outcome of time to exhaustion,which exhibits a small magnitude effect(SMD=0.37;p=0.002).Additionally,the placebo exhibited effects notably greater than the control condition(outcome:number of repetitions;SMD=0.45;p=0.03),suggesting a potential influence of participants'cognitive perception on the outcomes.However,the evidence is of moderate to low certainty,regardless of the comparison or outcome.Conclusion:IPC has significant effects compared to the control intervention,but it did not surpass the placebo condition.Its administration might be influenced by the cognitive perception of the receiving subject,and the efficacy of IPC as an ergogenic strategy for enhancing exercise capacity and athletic performance remains questionable. 展开更多
关键词 DECEPTION Nocebo effects Athletic performance REPERFUSION TOURNIQUETS
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Sport climbing performance determinants and functional testing methods:A systematic review
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作者 Sara Faggian Nicola Borasio +8 位作者 Marco Vecchiato Hannes Gatterer Martin Burtscher Francesca Battista Hannes Brunner Giulia Quinto Federica Duregon Andrea Ermolao Daniel Neunhaeuserer 《Journal of Sport and Health Science》 2025年第2期1-20,共20页
Background:Sport climbing is becoming incredibly popular both in the general population and among athletes.No consensus exists regarding evidence-based sport-specific performance evaluation;therefore,this systematic r... Background:Sport climbing is becoming incredibly popular both in the general population and among athletes.No consensus exists regarding evidence-based sport-specific performance evaluation;therefore,this systematic review was aimed at analyzing determinants of sport climbing performance and evaluation methods by comparing climbers of different levels.Methods:PubMed,Scopus,and Web of Science were searched up to December 20,2022.Studies providing the self-reported climbing ability associated with different functional outcomes in groups of climbers of contiguous performance levels were eligible.Results:74 studies were finally included.Various methods have been proposed to evaluate determinants of sport climbing performance.Climbing-specific assessments were able to discriminate climbers of different levels when compared to general functional tests.Test validity resulted high for climbing-specific cardiorespiratory endurance as well as muscular-strength,-endurance,and-power;similarly,reliability was good except for cardiorespiratory endurance.Climbing-specific flexibility assessment resulted in high reliability but moderate validity,whereas balance showed low validity.Considerable conflicting evidence was found regarding anthropometric characteristics.Conclusion:The present analysis identified cardiorespiratory endurance as well as muscular-strength,-endurance,and-power as determinants of sport climbing performance.In contrast,balance,flexibility,and anthropometric characteristics seem to count less.This review also proposes an evidence-based Functional Sport Climbing test battery for asses sing performance determinants,which includes tests that have been identified to be valid,reliable,and feasible.While athletes and coaches should rely on evidence-based and standardized evaluation methods,researchers may design specific large-scale trials as a resource for providing additional,homogenous,and comparable data to improve scientific evidence and professionalism in this popular sport discipline. 展开更多
关键词 ENDURANCE STRENGTH Validity RELIABILITY
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Tree‑Inspired Structurally Graded Aerogel with Synergistic Water,Salt,and Thermal Transport for High‑Salinity Solar‑Powered Evaporation 被引量:2
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作者 Xiaomeng Zhao Heng Zhang +3 位作者 Kit‑Ying Chan Xinyue Huang Yunfei Yang Xi Shen 《Nano-Micro Letters》 SCIE EI CAS CSCD 2024年第11期19-37,共19页
Solar-powered interfacial evaporation is an energy-efficient solution for water scarcity.It requires solar absorbers to facilitate upward water transport and limit the heat to the surface for efficient evaporation.Fur... Solar-powered interfacial evaporation is an energy-efficient solution for water scarcity.It requires solar absorbers to facilitate upward water transport and limit the heat to the surface for efficient evaporation.Furthermore,downward salt ion transport is also desired to prevent salt accumulation.However,achieving simultaneously fast water uptake,downward salt transport,and heat localization is challenging due to highly coupled water,mass,and thermal transport.Here,we develop a structurally graded aerogel inspired by tree transport systems to collectively optimize water,salt,and thermal transport.The arched aerogel features root-like,fan-shaped microchannels for rapid water uptake and downward salt diffusion,and horizontally aligned pores near the surface for heat localization through maximizing solar absorption and minimizing conductive heat loss.These structural characteristics gave rise to consistent evaporation rates of 2.09 kg m^(-2) h^(-1) under one-sun illumination in a 3.5 wt%NaCl solution for 7 days without degradation.Even in a high-salinity solution of 20 wt%NaCl,the evaporation rates maintained stable at 1.94 kg m^(-2) h^(-1) for 8 h without salt crystal formation.This work offers a novel microstructural design to address the complex interplay of water,salt,and thermal transport. 展开更多
关键词 Composite aerogel Graded structure Solar-powered evaporation Thermal insulation Salt rejection
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The Role and the Function of Japan Institute of Sports Sciences and National Training Center in Japan
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作者 Kazuya Kasahara 《中国体育科技》 CSSCI 北大核心 2009年第1期30-32,共3页
Gold Medals in Summer Qlympics Measures A 1) Program to develop junior athletes to top level 2) National Training Center 3) National Coach Academy B 1) Sports medicine and sciences(JISS) 2) Anti-doping 3) To hold inte... Gold Medals in Summer Qlympics Measures A 1) Program to develop junior athletes to top level 2) National Training Center 3) National Coach Academy B 1) Sports medicine and sciences(JISS) 2) Anti-doping 3) To hold international 展开更多
关键词 The Role and the Function of Japan Institute of Sports Sciences and National Training Center in Japan
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Sports Participation and Depressive Symptoms in Youth:Demographic Differences
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作者 Yuanyuan Hao Dongye Lyu +2 位作者 Siyu Zhang Bin Guo Jin Yan 《International Journal of Mental Health Promotion》 2024年第10期865-873,共9页
Background:Youth emerge as an essential period in forming lifelong health and well-being.During adolescence,physical activity(PA)improves cardiovascular health,fitness levels,and the prevention of chronic illnesses,an... Background:Youth emerge as an essential period in forming lifelong health and well-being.During adolescence,physical activity(PA)improves cardiovascular health,fitness levels,and the prevention of chronic illnesses,and the positive effect is also extended to the mental realm,as PA reduces symptoms of anxiety and depression.Therefore,the current study aims to enhance our understanding of the correlation between sports participation and depressive symptoms.Additionally,it seeks to explore how demographics such as gender,age,and race can shape these connections.Methods:The research sample was established by utilising the U.S.Youth Risk Behavior Surveillance(YRBS)2019 cycle,and the eligible samples from this cycle were included in the current study.A self-administered survey evaluated sports participation,categorized as Zero,one,two,three,or more teams.This study included 16,104 participants and conducted self-reported questionnaires on gender,grade,race/ethnicity,and depressive symptoms.The study had a nationally representative population of American students in Grades 10 to 12(aged 14–17 years).Results:A total of 7843 females and 8261 males,distributed across age groups(14 years old,15 years old,16 years old,and 17 years old),with the numbers 3430,4445,4300,and 3929,respectively.Overall,there was a negative correlation between sports participation and feelings of sadness(a symptom of depression)among the subjects.This significant relationship between participating in sports teams and experiencing sadness was dose dependent.Conclusion:Youth with more team sports participation is likely to display lower depression symptoms,and differences in demographic factors such as gender,race,and age are detected.Physical activity research is responsible for attending to social equity issues and fostering inclusiveness,particularly concerning different gender and ethnic groups. 展开更多
关键词 Sport participation DEPRESSIVE YOUTH youth risk behavior surveillance RACE
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Movement analysis in the diagnosis and management of Parkinson’s disease 被引量:1
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作者 Johannes Burtscher Nicolas Bourdillon +5 位作者 Jules MJanssen Daalen Aurélien Patoz Julien FBally Martin Kopp Davide Malatesta Bastiaan RBloem 《Neural Regeneration Research》 SCIE CAS 2025年第2期485-486,共2页
Challenges in the diagnosis and treatment of Parkinson’s disease:Parkinson’s disease(PD)is an increasingly prevalent neurodegenerative disease,at first sight primarily characterized by motor symptoms,although non-mo... Challenges in the diagnosis and treatment of Parkinson’s disease:Parkinson’s disease(PD)is an increasingly prevalent neurodegenerative disease,at first sight primarily characterized by motor symptoms,although non-motor symptoms also constitute a major part of the overall phenotype.Clinically,this disease cannot be diagnosed reliably until a large part of the vulnerable dopaminergic neurons has been irretrievably lost,and the disease progresses inexorably.New biological criteria for PD have been proposed recently and might eventually improve early diagnosis,but they require further validation,and their use will initially be restricted to a research environment(Darweesh et al.,2024). 展开更多
关键词 DIAGNOSIS CLINICAL eventually
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The wearable landscape: Issues pertaining to the validation of the measurement of 24-h physical activity, sedentary, and sleep behavior assessment 被引量:2
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作者 Marco Giurgiu Birte von Haaren-Mack +16 位作者 Janis Fiedler Simon Woll Alexander Burchartz Simon Kolb Sascha Ketelhut Claudia Kubica Carina Nigg Irina Timm Maximiliane Thron Steffen Schmidt Kathrin Wunsch Gerhard Muller Claudio RNigg Alexander Woll Markus Reichert Ulrich Ebner-Priemer Johannes BJ Bussmann 《Journal of Sport and Health Science》 2025年第3期131-139,共9页
The ongoing revolution in information technology is reshaping human life. In the realm of health behavior, wearable technology emerges as a leading digital solution,capturing physical behaviors (i.e., physical activit... The ongoing revolution in information technology is reshaping human life. In the realm of health behavior, wearable technology emerges as a leading digital solution,capturing physical behaviors (i.e., physical activity, sedentary habits, sleep patterns) within the 24-h cycle of daily life. Wearables are applied in research, clinical practice, and as lifestyle devices;most obvious, they promise to be a key element for increasing human physical activity, one of the biggest health challenges nowadays. 展开更多
关键词 increasing human physical activityone lifestyle devicesmost validation studies health behaviorwearable technology revolution information technology wearable technology physical activity physical behaviors iephysical
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Hypoxia Exercise Mediates The miR-27/PPARγ Pathway to Improve Lipid Metabolism in Obese Ratsat Target Genes and Protein Levels
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作者 KONG Wei SHAO Jie +4 位作者 ZHAI Teng CHENG Qian HAN Fang-Zheng QU Yi ZHU Lei 《生物化学与生物物理进展》 北大核心 2025年第6期1386-1400,共15页
Objective To explore the sequential effects of hypoxic exercising on miR-27/PPARγand lipid metabolism targetgene and protein expression levels in the obesity rats’liver.Methods 13-week-old male diet-induced obesity ... Objective To explore the sequential effects of hypoxic exercising on miR-27/PPARγand lipid metabolism targetgene and protein expression levels in the obesity rats’liver.Methods 13-week-old male diet-induced obesity rats were randomlydivided into three groups(n=10):normal oxygen concentration quiet group(N),hypoxia quiet group(H),hypoxic exercise group(HE).Exercise training on the horizontal animal treadmill for 1 h/d,5 d/week for a total of 4 week,and the intensity of horizontaltreadmill training was 20 m/min(hypoxic concentration was 13.6%).Comparison of the weights of perirenal fat and epididymal fat in rats across different groups and calculation of Lee’s index based on body weight and body length of rats in each group were done.And the serum concentrations of total cholesterol(TC),triglyceride(TG),low density lipoprotein cholesterol(LDL-C),high-densitylipoprotein cholesterol(HDL-C)levels were detected.RT-PCR and Western Blot were used to detect the levels of miR-27,PPARγ,CYP7A1 and CD36.Results Hypoxic exercise decreased the expression levels of miR-27 in the obese rats’liver,however,theexpression level of PPARγwas gradually increased.The expression levels of miR-27 in HE group were significantly lower than Ngroup(P<0.05).The expression levels of PPARγmRNA in N group were significantly lower than H group(P<0.05),especially lowerthan HE group(P<0.01).The protein expression of PPARγprotein in N group was significantly lower than that other groups(P<0.01).The expression of lipid metabolism-related genes and proteins increased in the obese rats’liver.The expression of CYP7A1mRNA in N group was significantly lower than H group(P<0.05),especially lower than HE group(P<0.01).The expression ofCYP7A1 protein in the obese rats’liver in N group was extremely lower than H group and HE group(P<0.01).The proteinexpression of CD36 in N group was significantly lower than that in HE group(P<0.05).Hypoxia exercise improved the relatedphysiological and biochemical indexes of lipid metabolism disorder.The perirenal fat weight of obese rats in HE group wasextremely lower than N group and H group(P<0.01),and the perirenal fat weight in N group was significantly higher than H group(P<0.05).The epididymal fat weight in N group was significantly higher than H group(P<0.05),and extremely higher than HEgroup(P<0.01).The Lee’s index in HE group was extremely lower than N group and H group(P<0.01).The serum concentration ofTC in obese rats in HE group was extremely lower than N group and H group(P<0.01).The serum concentration of TG in HE groupwas extremely lower than N group and H group(P<0.01).The serum concentration of LDL-C in N group was extremely higher thanHE group(P<0.01).The serum concentration of HDL-C in N group was extremely lower than H group(P<0.01).Conclusion Hypoxiaand hypoxia exercise may negatively regulate the levels of PPARγby inhibiting miR-27 in the obese rats’liver,thereby affecting theexpression of downstream target genes CYP7A1 and CD36,and promoting cholesterol,fatty acid oxidation and HDL-C transport inthe liver,and ultimately the lipid levels in obese rats were improved.The effect of hypoxia exercise on improving blood lipid isbetter than simple hypoxia intervention. 展开更多
关键词 hypoxia exercise miR-27 peroxisome proliferators-activated receptor gamma obese rat
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Effect of Mindfulness Behavioral Training Combined with Exercise Intervention on Postoperative Functional Recovery and Quality of Life in Elderly Patients with Lumbar Spine Fractures
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作者 Cao Xinhan 《Asia Pacific Journal of Clinical Medical Research》 2025年第1期22-29,共8页
Objective:To investigate the positive eff ect of mindfulness training and exercise therapy on functional recovery and quality of life in elderly patients with fractures of the lower back.Methods:Collection of medical ... Objective:To investigate the positive eff ect of mindfulness training and exercise therapy on functional recovery and quality of life in elderly patients with fractures of the lower back.Methods:Collection of medical records of patients with lumbar vertebral fractures in Suzhou Municipal Hospital(North District),60 patients underwent percutaneous vertebroplasty(PVP/PKP),they were divided into control and experimental groups according to a random number table,30 people per group;In addition to traditional care method,Also intervened with behavioural awareness training and exercise therapy,By comparing the Oswestry dysfunction index score(ODI),visual simulation score(VAS),ability of daily living score(ADL),quality of life score(SF-36),To evaluate the eff ectiveness of the intervention.Results:Before the intervention,the ODI,VAS,ADL,and SF-36 scores were basically the same,with no significant diff erence(P>0.05).After treatment,the ODI and VAS scores of the experimental group and the control group were signifi cantly lower,and the experimental group was significantly lower than the control group(P<0.05);the ADL scores of the experimental group were signifi cantly higher than those of the control group(P<0.05);their SF-36 quality of life scores in all dimensions were signifi cantly higher(P<0.05).Conclusion:Through the rehabilitation treatment method combining mindfulness behavior training and exercise intervention,it can eff ectively promote the functional recovery of osteoporotic lumbar fractures in the elderly,thus reducing their pain and improving their quality of life. 展开更多
关键词 Mindfulness Training Exercise Intervention OSTEOPOROSIS Fracture of Lumbar Vertebrae Functional Recovery Quality of Life
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Role of RNA-binding proteins in exercise-induced mRNA regulation:Unveiling biomarkers and therapeutic targets for schizophrenia
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作者 Yao Lu Jian-Da Kong Lu-Nan Zhao 《World Journal of Psychiatry》 2025年第9期95-110,共16页
This article summarizes recent advances in the understanding of RNA-binding proteins(RBPs),with a focus on their roles in exercise-induced mRNA regulation and their implications for schizophrenia(SZ).RBPs are critical... This article summarizes recent advances in the understanding of RNA-binding proteins(RBPs),with a focus on their roles in exercise-induced mRNA regulation and their implications for schizophrenia(SZ).RBPs are critical regulators of mRNA stability,splicing,transport,translation,and degradation,directly influencing gene expression through sequence-and structure-specific binding.In the nervous system,RBPs sustain synaptic plasticity,neural development,and neuronal homeostasis.Emerging evidence shows that exercise modulates the expression and activity of RBPs,thereby influencing mRNA translation and neurotransmitter signaling,which may underlie its beneficial effects on brain function.Dysregulation of specific RBPs has been identified in SZ,implicating them in disrupted synaptic transmission,impaired plasticity,and neuroinflammation.RBPs involved in memory and emotional regulation show marked dysfunction in SZ patients.Some RBPs have been proposed as potential biomarkers for early diagnosis and treatment monitoring.Moreover,therapeutic modulation of RBPs,through pharmacological or behavioral interventions such as exercise,may restore neuronal function by targeting post-transcriptional gene regulation.Exercise,as a non-invasive modulator of RBP expression,holds promise as an adjunctive strategy in SZ treatment,particularly in early stages.Further research into RBP-mediated pathways may offer novel insights into SZ pathophysiology and inform the development of targeted interventions. 展开更多
关键词 RNA-binding proteins EXERCISE-INDUCED MRNA SCHIZOPHRENIA Biomarkers Therapeutic targets
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NG2 Glia:The Guardians Against Prion‑induced Neurotoxicity Through Prostaglandin E2 Blockade
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作者 Shu Feng Emily Parker +1 位作者 Timon Cheng‑Yi Liu Luodan Yang 《Neuroscience Bulletin》 2025年第3期539-542,共4页
Neuron glia antigen-2(NG2)glia,also known as oligodendrocyte precursor cells(OPCs),are essential for maintaining the normal function and structure of the central nervous system(CNS)due to their supportive role[1].Unde... Neuron glia antigen-2(NG2)glia,also known as oligodendrocyte precursor cells(OPCs),are essential for maintaining the normal function and structure of the central nervous system(CNS)due to their supportive role[1].Under physiological conditions,NG2 glia are involved in myelination by differentiating into oligodendrocytes,which are responsible for forming the myelin sheath around axons[2].In addition,the NG2 glia can directly influence the activity of neuronal circuits by receiving synaptic input from neurons and generating action potentials[3].Under pathological conditions,such as in response to injury or disease,the NG2 glia proliferate and differentiate to replace damaged oligodendrocytes,contributing to the repair and regeneration of myelin[4]. 展开更多
关键词 maintaining normal function structure myelin sheath axons oligodendrocyte precursor cells opcs receiving synaptic input neurons NEUROTOXICITY PRION central nervous system cns due ng glia
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Effect of High-Intensity Interval Training on Muscle Strength Growth in Athletes
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作者 Yang Jiao 《Journal of Contemporary Educational Research》 2025年第10期408-414,共7页
High-intensity interval training(HIIT),a highly efficient and distinctive exercise format,has sparked growing academic interest in sports performance training.This article synthesizes theoretical and applied evidence ... High-intensity interval training(HIIT),a highly efficient and distinctive exercise format,has sparked growing academic interest in sports performance training.This article synthesizes theoretical and applied evidence to analyze mechanisms of HIIT in neuromuscular activation,hormonal responses,muscle fiber adaptation,and metabolic pathway effects.It focuses on its effectiveness in enhancing explosive power,maximum strength,and strength endurance,while also examining the integration of HIIT with traditional resistance training,periodized programming,and personalized prescription.Scientific implementation of HIIT can effectively diversify or even replace conventional strength training,not only offering positive directional changes for strength development but also introducing innovative approaches to sports performance training practices. 展开更多
关键词 High-intensity interval training Muscle strength ATHLETES Intervention effect
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Managing lower extremity loading in distance running by altering sagittal plane trunk leaning
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作者 Luca Braun Patrick Mai +6 位作者 Markus Hipper Yannick Denis Janina Helwig Bastian Anedda Burkay Utku Dominic Gehring Steffen Willwacher 《Journal of Sport and Health Science》 2025年第2期35-45,共11页
Background:Trunk lean angle is an underrepre sented biomechanical variable for modulating and redistributing lower extremity joint loading and potentially reducing the risk of running-related overuse injuries.The purp... Background:Trunk lean angle is an underrepre sented biomechanical variable for modulating and redistributing lower extremity joint loading and potentially reducing the risk of running-related overuse injuries.The purpose of this study was to systematically alter the trunk lean angle in distance running using an auditory real-time feedback approach and to derive dose-response relationships between sagittal plane trunk lean angle and lower extremity(cumulative)joint loading to guide overuse load management in clinical practice.Methods:Thirty recreational runners(15 males and 15 females)ran at a constant speed of 2.5 m/s at 5 systematically varied trunk lean conditions on a force-instrumented treadmill while kinematic and kinetic data were captured.Results:A change in trunk lean angle from-2°(extension)to 28°(flexion)resulted in a systematic increase in stance phase angular impulse,cumulative impulse,and peak moment at the hip joint in the sagittal and transversal plane.In contrast,a systematic decrease in these parameters at the knee j oint in the sagittal plane and the hip joint in the frontal plane was found(p<0.001).Linear fitting revealed that with every degree of anterior trunk leaning,the cumulative hip joint extension loading increases by 3.26 Nm·s/kg/1000 m,while simultaneously decreasing knee joint extension loading by 1.08 Nm·s/kg/1000 m.Conclusion:Trunk leaning can reduce knee joint loading and hip joint abduction loading,at the cost of hip joint loading in the sagittal and transversal planes during distance running.Modulating lower extremity joint loading by altering trunk lean angle is an effective strategy to redistribute joint load between/within the knee and hip joints.When implementing anterior trunk leaning in clinical practice,the increased demands on the hip musculature,dynamic stability,and the potential trade-off with running economy should be considered. 展开更多
关键词 Cumulative loading Overuse injuries Trunk orientation Locomotion
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The Effects of Physical Activity on Cognitive Function in People with Mild Cognitive Impairment: A Meta-Analysis
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作者 Jonghwa Lee Youngho Kim Dojin An 《International Journal of Mental Health Promotion》 2025年第3期257-270,共14页
Objectives:The current study aimed to perform a meta-analysis to comprehensively investigate effect of physical activity on cognitive function in people with Mild Cognitive Impairment.The findings of this study can of... Objectives:The current study aimed to perform a meta-analysis to comprehensively investigate effect of physical activity on cognitive function in people with Mild Cognitive Impairment.The findings of this study can offer an important basis for identifying the significance of physical activity as an important factor in designing and implementing strategies to enhance cognitive function in mild cognitive impairment.Methods:21 articles were selected through academic databases(EBSCOhost,PubMed,ScienceDirect,Web of Science),and 20 Montreal Cognitive Assessment(MoCA)data and 15 Mini-Mental State Examination(MMSE)data were obtained.The study was conducted using the meta-analysis.To test the validity of each article included in this study,a funnel plot and Egger’s regression analysis were carried out to check for publication bias.Results:The 95%confidence interval(CI)for the effect size was interpreted as a small effect size if the effect size was between 0.2 and 0.5,a moderate effect size if the effect size was between 0.5 and 0.8,and large if the effect size was greater than 0.8.First,the meta-analysis of MoCA data showed a large effect size of 0.96;second,the meta-analysis of MMSE data indicated a large effect size of 0.93;and third,the meta-analysis of MoCA and MMSE data together indicated a moderate effect size of 0.68.Conclusion:The current study demonstrates the significant effect of physical activity on cognitive function and provides a basis for developing programs to improve cognitive function.People diagnosed with mild cognitive impairment generally experience minimal disruption in daily living activities.However,as the severity of the condition progresses,significant challenges emerge,impacting the individual’s ability to carry out daily tasks.Research has demonstrated that physical activity can enhance cognitive function in individuals with MCI.Consequently,it is recommended that these individuals be motivated to participate in physical activity to optimize their cognitive function and enhance their overall quality of life. 展开更多
关键词 Physical activity mild cognitive impairment(MCI) montreal cognitive assessment(MoCA) mini-
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Effect of empowerment-based interventions on self-efficacy and selfcare capacity among patients with sickle cell disease:A randomized controlled trial
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作者 Zohour Ibrahim Rashwan Hasan Abdali Khalil +5 位作者 Leena Mohamed Khonji Gayathripriya Narayanan Marwan Kamal Altheeb Roseben Pradeep Rajeswari Krishnasamy Magda Mohamed Bayoumi 《International Journal of Nursing Sciences》 2025年第1期42-50,共9页
Objective:This study aimed to investigate the effect of empowerment-based interventions on selfefficacy and self-care capacity among adults with sickle cell disease(SCD).Methods:A randomized control trial was conducte... Objective:This study aimed to investigate the effect of empowerment-based interventions on selfefficacy and self-care capacity among adults with sickle cell disease(SCD).Methods:A randomized control trial was conducted[NCT06296654].A total of 76 patients were recruited by using a cluster sampling technique in the two health centers in Bahrain from February to May 2022 and randomly allocated to the intervention group(n=38)or control group(n=38).The intervention group received the empowerment-based intervention implemented through structured small-group discussion sessions,individualized consultations(5A model:assess,advise,agree,assist,and arrange),and follow-up sessions,while the control group received routine health education.The Sickle Cell Self-Efficacy Scale(SCSES)and the Appraisal of the Self-Care Agency Scale-Revised(ASA-R)were measured at baseline and one month after the intervention among two groups of patients.Results:A total of 68 patients completed the study(36 patients in the intervention group and 32 patients in the control group).After the intervention,the score of SCSES in the intervention group was 37.0(35.0,39.8)higher than the control group 28.0(25.2,32.0)(U=-6.121,P<0.001);the score of ASA-R in the intervention group was 61.0(58.3,65.0)higher than the control group 49.0(43.3,53.0)(U=-0.653,P<0.001).Conclusion:Adopting the empowerment-based intervention using the 5As model effectively improves self-efficacy and self-care capacity among patients with SCD. 展开更多
关键词 Activities of daily living Sickle cell disease SELF-EFFICACY SELF-CARE
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Associations of adiposity and device-measured physical activity with cancer incidence: UK Biobank prospective cohort study
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作者 Miguel Adriano Sanchez-Lastra Tessa Strain +4 位作者 Ding Ding Knut Eirik Dalene Borja del Pozo Cruz Ulf Ekelund Jakob Tarp 《Journal of Sport and Health Science》 2025年第3期13-22,共10页
Background:High adiposity and low physical activity are associated with cancer risk.Whether different amounts and intensities of physical activity can mitigate this association is unclear.We aimed to examine the indep... Background:High adiposity and low physical activity are associated with cancer risk.Whether different amounts and intensities of physical activity can mitigate this association is unclear.We aimed to examine the independent and combined associations of adiposity and devicemeasured physical activity levels of different intensities with cancer incidence and mortality.Methods:This prospective cohort study included data from 70,747 UK Biobank participants(mean age=61.6±7.9 years,mean±SD;56.4%women)with wrist-worn accelerometer measurements of physical activity and without chronic diseases or mobility limitations.Physical activity exposures included min per week of light intensity physical activity(LPA),moderate-to-vigorous intensity physical activity(MVPA),and vigorous intensity physical activity(VPA),along with total weekly volume.Body mass index(BMI)was calculated from anthropometric measurements.Participants were categorized into 9 groups based on joint tertiles of physical activity and BMI categories(normal weight,overweight,and obesity).Secondary analyses included adiposity using bio-impedance and waist circumference measurements.The outcome was incidence and death from cancer retrieved from national registries.Associations between adiposity,physical activity,and cancer hazard were calculated as subdistribution hazard ratios.A secondary analysis focused on cancer types strongly associated with physical activity.Results:We observed 2625 events(2572 non-fatal and 53 fatal)during a median follow-up of 6.1 years.Compared with the referent(normal weight and high physical activity),overweight and obesity were associated with a 6%to 36%higher cancer hazard across physical activity intensities.However,high MVPA and VPA(approximately 500 min and 32 min per week in the top tertiles,respectively)attenuated the hazard associated with overweight and obesity.Being normal weight was not associated with a higher cancer hazard regardless of physical activity level.The results were similar,although more pronounced,when modeling cancer types strongly associated with physical activity as the outcome.Conclusion:High MVPA and VPA levels may attenuate the association of overweight and obesity with cancer hazard,but maintaining a normal weight seems comparatively more important than physical activity to reduce the hazard.Maintaining a healthy body weight and engaging in physical activity is needed to minimize risk of some cancer types. 展开更多
关键词 Public health Cancer prevention Cancer mortality ACCELEROMETER OBESITY
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