Coriolus versicolor has been reported to have biological activities such as anticancer, antibacterial, antibiotics and immunopotentiation. The authors tried to ferment using lactobacilli associated with various biolog...Coriolus versicolor has been reported to have biological activities such as anticancer, antibacterial, antibiotics and immunopotentiation. The authors tried to ferment using lactobacilli associated with various biological functions and expected that fermented extract by lactobacilli will be superior to non-fermented extract in antioxidant activity. C. versicolor was extracted with 70% ethanol and then it was fermented by Lactobacillus acidophilus KCTC3164 and Lactobacillus plantarum KCTC3099, respectively. 1,l-dipheny｜-2-picrylhydrazyl （DPPH） scavenging activity, superoxide dismutase （SOD）-like activity and tetrazolium salt 3-（4,5-dimethylthiazol-2-yl）-2,5-diphenyltetrazolium bromide （MTT） assays were performed. DPPH scavenging activity of fermented extract by L. acidophilus was higher than fermented extract by L. plantarum and antioxidant effect of fermented extract was 20%-30% higher than non-fermented extract. SOD-like activity was represented 18% in fermented extract by L. acidophilus, and was 27% in fermented extract by L. plantarum higher than non-fermented extract. As a result, this study suggests that it may need an efficient protocol for dominant bio-physiological activities such as extract volume or appropriate working volume of cultured cell or mixture condition. The fermented C. versicolor extract should provide with useful antioxidant agent in the human skin.展开更多
The vertebrate limb development serves as an excellent model in morphology,developmental biology,and evolutionary studies owing to its remarkable morphological and functional diversity.Forelimbs and hindlimbs originat...The vertebrate limb development serves as an excellent model in morphology,developmental biology,and evolutionary studies owing to its remarkable morphological and functional diversity.Forelimbs and hindlimbs originate from the lateral plate mesoderm(LPM),located along the embryo’s flank,with the initiation of differential expression of the transcription factors TBX5 for the forelimb and TBX4 and PITX1 for the hindlimb.Initially,limbs emerge as small buds comprising an undifferentiated mesodermal core covered by a layer of ectoderm[1].展开更多
文摘Coriolus versicolor has been reported to have biological activities such as anticancer, antibacterial, antibiotics and immunopotentiation. The authors tried to ferment using lactobacilli associated with various biological functions and expected that fermented extract by lactobacilli will be superior to non-fermented extract in antioxidant activity. C. versicolor was extracted with 70% ethanol and then it was fermented by Lactobacillus acidophilus KCTC3164 and Lactobacillus plantarum KCTC3099, respectively. 1,l-dipheny｜-2-picrylhydrazyl （DPPH） scavenging activity, superoxide dismutase （SOD）-like activity and tetrazolium salt 3-（4,5-dimethylthiazol-2-yl）-2,5-diphenyltetrazolium bromide （MTT） assays were performed. DPPH scavenging activity of fermented extract by L. acidophilus was higher than fermented extract by L. plantarum and antioxidant effect of fermented extract was 20%-30% higher than non-fermented extract. SOD-like activity was represented 18% in fermented extract by L. acidophilus, and was 27% in fermented extract by L. plantarum higher than non-fermented extract. As a result, this study suggests that it may need an efficient protocol for dominant bio-physiological activities such as extract volume or appropriate working volume of cultured cell or mixture condition. The fermented C. versicolor extract should provide with useful antioxidant agent in the human skin.
基金supported by the National Key Research and Development Program(2022YFA1104900 and 2019YFA0801703)the National Natural Science Foundation of China(31871370)。
文摘The vertebrate limb development serves as an excellent model in morphology,developmental biology,and evolutionary studies owing to its remarkable morphological and functional diversity.Forelimbs and hindlimbs originate from the lateral plate mesoderm(LPM),located along the embryo’s flank,with the initiation of differential expression of the transcription factors TBX5 for the forelimb and TBX4 and PITX1 for the hindlimb.Initially,limbs emerge as small buds comprising an undifferentiated mesodermal core covered by a layer of ectoderm[1].
